Blood-brain barrier transport of H1-antagonist ebastine and its metabolite carebastine

Journal of Drug Targeting

Volumn 8, Issue 6, 2000, Pages 383-393

  Tamai, I ^a   Kido, Y ^a   Yamashita, J ^a   Sai, Y ^a   Tsuji, A ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; Efflux; H1 antagonist; P gp; Transport

Indexed keywords

AMPHOLYTE; CARBON 14; CARBOXYLIC ACID; CAREBASTINE; CYPROHEPTADINE; DRUG METABOLITE; EBASTINE; FEXOFENADINE; GLYCOPROTEIN P; HISTAMINE H1 RECEPTOR ANTAGONIST; MEPYRAMINE; TERFENADINE; TRITIUM; VERAPAMIL; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CAPILLARY ENDOTHELIUM; CATTLE; CELL CULTURE; CELL IMMORTALIZATION; CELL STRAIN K 562; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG LABELING; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG TRANSPORT; ENDOTHELIUM CELL; ERYTHROLEUKEMIA CELL; FIRST PASS EFFECT; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEADY STATE;

EID: 0034452788     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611860008997914     Document Type: Article

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