Activity, stereospecificity, and stereoselectivity of microsomal enzymes in dependence on storage and freezing of rat liver samples

Chirality

Volumn 12, Issue 9, 2000, Pages 649-653

  Skálová, Lenka ^a   Szotáková, Barbora ^a   Wsól, Vladimír ^a   Král, Radim ^a   Baliharová, Vendula ^a   Lamka, Jiří ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

Author keywords

11 dihydrooracin; Biotransformation; Chiral stationary phase; Cytochrome P450; HPLC; Liver handling; Microsomal reduction; Oracin

Indexed keywords

11 DIHYDROORACIN; CYTOCHROME P450; ICE; LIQUID NITROGEN; MICROSOME ENZYME; ORACIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; COOLING; ENZYME ACTIVITY; ENZYME STRUCTURE; FEMALE; FREEZING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; REDUCTION; STEREOCHEMISTRY; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; TIME; TISSUE PREPARATION; TISSUE PRESERVATION;

ALCOHOL OXIDOREDUCTASES; ANIMALS; BIOTRANSFORMATION; CRYOPRESERVATION; CYTOCHROME P-450 ENZYME SYSTEM; ETHANOLAMINES; FEMALE; HUMANS; ISOQUINOLINES; MICROSOMES, LIVER; OXIDATION-REDUCTION; RATS; RATS, WISTAR; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TIME FACTORS;

EID: 0034425173     PISSN: 08990042     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-636X(2000)12:9<649::AID-CHIR1>3.0.CO;2-4     Document Type: Article

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