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Volumn 5, Issue 3-4, 2000, Pages 263-270
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The main metabolic pathway of oracin, a new potential cytostatic drug, in human liver microsomes and cytosol: Stereoselectivity of reoxidation of the principal metabolite 11-dihydrooracin to oracin
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Author keywords
Biotransformation; Chiral; Cytostatics; Man; Oracin; Stereospecificity
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Indexed keywords
11 DIHYDROORACIN;
ALCOHOL DEHYDROGENASE;
CARBONYL REDUCTASE;
CYTOCHROME P450;
CYTOSTATIC AGENT;
DRUG METABOLITE;
HYDROXYSTEROID DEHYDROGENASE;
NICOTINAMIDE ADENINE DINUCLEOTIDE;
ORACIN;
OXIDOREDUCTASE;
REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;
UNCLASSIFIED DRUG;
AEROBIC METABOLISM;
ANAEROBIC METABOLISM;
CHIRALITY;
COENZYME;
CONFERENCE PAPER;
CONTROLLED STUDY;
DRUG METABOLISM;
DRUG STRUCTURE;
DRUG TRANSFORMATION;
ENANTIOMER;
ENZYME MECHANISM;
ENZYME SUBSTRATE;
FEMALE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN TISSUE;
IN VITRO STUDY;
LIVER CYTOSOL;
LIVER MICROSOME;
MALE;
OXIDATION;
PRIORITY JOURNAL;
STEREOCHEMISTRY;
ALCOHOL OXIDOREDUCTASES;
ANTINEOPLASTIC AGENTS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CYTOSOL;
ETHANOLAMINES;
HUMANS;
ISOQUINOLINES;
MICROSOMES, LIVER;
OXIDATION-REDUCTION;
STEREOISOMERISM;
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EID: 0033645931
PISSN: 10242430
EISSN: None
Source Type: Journal
DOI: None Document Type: Conference Paper |
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Times cited : (15)
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References (14)
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