Bacterial interplay at intestinal mucosal surfaces: Implications for vaccine development

Trends in Microbiology

Volumn 8, Issue 10, 2000, Pages 457-464

  Autenrieth, Ingo B ^a   Schmidt, M Alexander ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL PROTEIN; CARRIER PROTEIN; CD18 ANTIGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; HEMOLYSIN; LIVE VACCINE; VACCINE; VIRULENCE FACTOR;

BACTERIAL INFECTION; CELL ACTIVATION; CELL ADHESION; CELL LINE; CYTOTOXICITY; DIARRHEA; EPITHELIUM CELL; ESCHERICHIA COLI; FIMBRIA; GENE EXPRESSION; GENE LOCUS; GENE TRANSFER; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; INTESTINE CELL; INTESTINE MUCOSA; MODEL; MOLECULAR RECOGNITION; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN TRANSPORT; REVIEW; SALMONELLA; SEQUENCE ANALYSIS; SHIGELLA;

BACTERIAL PROTEINS; BACTERIAL VACCINES; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; HUMAN; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; SUPPORT, NON-U.S. GOV'T; VIRULENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SALMONELLA; SHIGELLA; YERSINIA;

EID: 0034307328     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-842X(00)01828-X     Document Type: Review

References (67)

1. Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution
2. Spontaneous deletions and flanking regions of the chromosomal inherited hemolysin determinant of an Escherichia coli O6 strain
3. Pathogenicity islands: bacterial evolution in quantum leaps
4. The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus
5. The virulence plasmid of Yersinia, an antihost genome
6. Type III protein secretion systems in bacterial pathogens of animals and plants
7. Type III secretion machines: bacterial devices for protein delivery into host cells
8. Type III machines of Gram-negative bacteria: delivering the goods
9. From flagellum assembly to virulence: the extended family of type III export chaperones
10. Yop effectors of Yersinia spp. and actin rearrangements
11. Supramolecular structure of the Shigella type III secretion machinery: the needle part is changeable in length and essential for delivery of effectors
12. Type III machines of Gram-negative pathogens: injecting virulence factors into host cells and more
13. Components of the Salmonella flagellar export apparatus and classification of export substrates
14. Diffusely adhering Escherichia coli strains induce attaching and effacing phenotypes and secrete homologues of Esp proteins
15. Enteropathogenic E. coli (EPEC) transfer its receptor for intimate adherence into mammalian cells
16. Agents that inhibit Rho, Rac and Cdc2 do not block formation of actin pedestals in HeLa cells infected with enteropathogenic Escherichia coli
17. Increased levels of intracellular calcium are not required for the formation of attaching and effacing lesions by enteropathogenic and enterohemorrhagic Escherichia coli
18. Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability
19. Secretion of hybrid proteins by the Yersinia Yop export system
20. Delineation and mutational analysis of the Yersinia pseudotuberculosis YopE domains which mediate translocation across bacterial and eukaryotic cellular membranes
21. A mRNA signal for the type III secretion of Yop proteins by Yersinia enterocolitica
22. N-terminal conservation of putative type III secreted effectors of Salmonella typhimurium
23. A conserved amino acid sequence directing intracellular type III secretion by Salmonella typhimurium
24. Yersinia enterocolitica type III secretion: an mRNA signal that couples translation and secretion of YopQ
25. Customized secretion chaperones in pathogenic bacteria
26. Two independent type III mechanisms for YopE in Yersinia enterocolitica
27. Reciprocal secretion of proteins by the bacterial type III machines of plant and animal pathogens suggests universal recognition of mRNA targeting signals
28. The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact dependent membrane disrupting activity
29. The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranes
30. The Escherichia coli haemolysin secretion apparatus: a potential universal antigen delivery system in Gram-negative bacterial vaccine carriers
31. ABC transporters: bacterial exporters revisited five years on
32. Membrane association and multimerization of secreton component pulC
33. The complete general secretory pathway in Gram-negative bacteria
34. Processing of the AIDA-I precursor: removal of AIDA and evidence for the outer membrane anchoring as a b-barrel structure
35. Characterization of the essential transport function of the AIDA-I autotransporter and evidence supporting structural predictions
36. The great escape: structure and function of the autotransporter proteins
37. Gene structure and extracellular secretion of Neisseria gonorrhoea IgA1 protease
38. Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis
39. Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria
40. Molecular and cellular basis of immune protection of mucosal surfaces
41. Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles
42. Epithelial M cells: gateways for mucosal infection and immunization
43. Differential expression of lectin-binding sites defines mouse intestinal M-cells
44. Up-regulation of microsphere transport across the follicle-associated epithelium of Peyer's patch by exposure to Streptococcus pneumoniae R36A
45. Rapid appearance of M cells after microbial challenge is restricted at the periphery of the follicle-associated epithelium of Peyer's patch
46. Penetration of M cells and destruction of Peyer's patches by Yersinia enterocolitica: an ultrastructural and histological study
47. Defense mechanisms in Peyer's patches and mesenteric lymph nodes against Yersinia enterocolitica involve integrins and cytokines
48. Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria
49. Yersinia enterocolitica invasin: a primary role in the initiation of infection
50. Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells
51. M-cell surface b1 integrin expression and invasin-mediated targeting of Yersinia pseudotuberculosis to mouse Peyer's patch M cells
52. Translocation of Yersinia enterocolitica across reconstituted intestinal epithelial monolayers is triggered by Yersinia invasin binding to β1 integrins apically expressed on M-like cells
53. Crystal structure of invasin: a bacterial integrin-binding protein
54. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
55. The lpf fimbrial operon mediates adhesion of Salmonella typhimurium to murine Peyer's patches
56. Intestinal epithelial cells as watchdogs for the natural immune system
57. Yersinia enterocolitica invasin protein triggers differential production of IL-1, IL-8, MCP-1, GM-CSF and TNF-α in epithelial cells: implications for understanding the early cytokine network in Yersinia infection
58. Bacterial perturbation of cytokine networks
59. Organ-specific immune responses associated with infectious diseases
60. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes
61. Delivery of epitopes by the Salmonella type III secretion system for vaccine development
62. A recombinant Salmonella typhimurium vaccine strain is taken up and survives within murine Peyer's patch dendritic cells
63. Cell surface presentation of recombinant (poly-)peptides including functional T-cell epitopes by the AIDA autotransporter system
64. Yersinia enterocolitica invasin protein triggers IL-8 production via activation of Rel p65-p65 homodimers
65. Very late antigen-4-dependent adhesion and costimulation of resting human T cells by the bacterial β1 integrin ligand invasin
66. Efficacy of single-dose live oral cholera vaccine CVD 103-HgR in Noth Jakarta, Indonesia, a cholera-endemic area
67. Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteria