Intranasal Immunization of Mice with CpG DNA Induces Strong Systemic and Mucosal Responses That Are Influenced by Other Mucosal Adjuvants and Antigen Distribution

Molecular Medicine

Volumn 6, Issue 10, 2000, Pages 867-877

  McCluskie, Michael J ^a   Weeratna, Risini D ^a   Davis, Heather L ^a,b,c,d  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d PFIZER INC   (United States)

Author keywords

Hepatitis B Surface Antigen (HBsAg); Mucosal Adjuvant; Mucosal Immune Response; Natural Toxins; Nontoxic Derivatives

Indexed keywords

ANTIGEN; DNA; IMMUNOLOGICAL ADJUVANT; PRIMER DNA;

ANIMAL; ANTIBODY PRODUCTION; ARTICLE; BAGG ALBINO MOUSE; CELLULAR IMMUNITY; CPG ISLAND; DRUG EFFECT; GENETICS; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; MOUSE; MUCOSAL IMMUNITY; NUCLEOTIDE SEQUENCE;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODY FORMATION; ANTIGENS; BASE SEQUENCE; CPG ISLANDS; DNA; DNA PRIMERS; IMMUNITY, CELLULAR; IMMUNITY, MUCOSAL; MICE; MICE, INBRED BALB C;

MLCS; MLOWN;

EID: 0034295582     PISSN: 10761551     EISSN: 15283658     Source Type: Journal    
DOI: 10.1007/BF03401824     Document Type: Article

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