Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCRαβ repertoires and differential distribution in lymphoid tissues

Journal of Immunology

Volumn 165, Issue 5, 2000, Pages 2481-2490

  Apostolou, I ^a   Cumano, A ^a   Gachelin, G ^a   Kourilsky, P ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL SUBPOPULATION; FEMALE; LYMPHOID TISSUE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; T LYMPHOCYTE; THYMUS; TISSUE DISTRIBUTION;

EID: 0034283669     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.5.2481     Document Type: Article

References (48)

1. + thymocytes selected by MHC class I molecules
2. -T cells in mice and humans
3. + cells in the liver of mice
4. Mouse CD1-specific NK1 T cells: Development, specificity, and function
5. + T cells
6. - single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor Vβ family
7. + T cell populations
8. + T cells
9. + T lymphocytes
10. + T cells by CD1-expressing cortical thymocytes
11. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides
12. CD1d-mediated recognition of an α-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
13. Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells
14. + NK31 T lymphocytes
15. CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells
16. Syntheses of biotinylated α-galactosylceramides and their effects on the immune system and CD1 molecules
17. Binding and antigen presentation of cecamide-containing glycolipids by soluble mouse and human CD1d molecules
18. Tissue-specific segregation of CD1d-dependent and CD1d-independent NJ T cells
19. NKT cells are phenotypically and functionally diverse
20. Heterogeneity of NK1.1(+) T cells in the bone marrow: Divergence from the thymus
21. Tissue-specific recognition of mouse CD1 molecules
22. + targets
23. Rapid death and regeneration of NKT cells in anti-CD3ε- or IL-12-treated mice: A major role for bone marrow in NKT cell homeostasis
24. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor β chain vary as a function of the recombined germ-line segments
25. T-cell repertoire diversity and clonal expansions in normal and clinical samples
26. T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: Implications for T cell allelic exclusion and antigen-specific repertoire
27. The immunoscope approach for the analysis of T cell repertoires
28. Quantitative analysis of the T cell repertoire selected by a single peptide-major histocompatibility complex
29. The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments
30. T-cell receptor β-chain expression: Dependence on relatively few variable region genes
31. Size estimate of the αβ TCR repertoire of naive mouse splenocytes
32. Individual variations in the murine T cell response to a specific peptide reflect variability in naive repertoires
33. Differentiation of naive CTL to effector and memory CTL: Correlation of effector function with phenotype and cell division
34. Cutting edge: Activation of NJ T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype
35. Immunization with α-galactosylceramide polarizes CD1-reactive NJ T cells towards Th2 cytokine synthesis
36. Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide
37. The natural killer T (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin IL-12 production by dendritic cells and IL-12 receptor expression on NKT cells
38. + T cells in IL-12-induced immune responses in vivo
39. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors
40. Natural killer like non specific tumor cell lysis mediated by specific ligand activated Vα14 NKT cells
41. - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic NOD/Lt mice by the influence of intedeukin IL-4 and/or IL-10
42. A defect in interleukin 12-induced activation and interferon γ secretion of peripheral natural killer T cells in nonobese diabetic mice suggest new pathogenic mechanisms for insulin-dependent diabetes mellitus
43. + NJ T cells associated with disease development in autoimmune-prone mice
44. + T cells induces monocyte chemoattractant protein-1 in early listeriosis
45. + natural killer T cells by Mycobacterium bovis bacillus Calmette-Guerin
46. + T cells reciprocally regulate acute graft versus host disease
47. +NKT cells
48. + cells originate from multiple pathways