Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs

EMBO Journal

Volumn 19, Issue 17, 2000, Pages 4676-4687

  Yamagata, Tetsuya ^a   Mitani, Kinuko ^a   Oda, Hideaki ^a   Suzuki, Takahiro ^a   Honda, Hiroaki ^a   Asai, Takashi ^a   Maki, Kazuhiro ^a   Nakamoto, Tetsuya ^a   Hirai, Hisamaru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Acetylation; AICD; GATA 3; T cell homing

Indexed keywords

TRANSCRIPTION FACTOR GATA 3;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; GENE CONTROL; GENE DISRUPTION; GENE MUTATION; GENE TARGETING; IMMUNE SYSTEM; LYMPHOID ORGAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0034282480     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.17.4676     Document Type: Article

References (56)

1. The CBP coactivator is histone acetyltransferase
2. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation
3. Regulation of activation of the transcription factor GATA-1 by acetylation
4. Special HATs for special occasions: Linking histone acetylation to chromatin assembly and gene activation
5. Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
6. Nuclear receptor coactivator ACTR is a novel histone acetyltranferase and forms a multimeric activation complex with P/CAF and CBP/p300
7. Autocrine T-cell suicide mediated by APO-1/Fas/CD95
8. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
9. Embryonic expression and cloning of the murine GATA-3 gene
10. Histone acetylation in chromatin structure transcription
11. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
12. Requirement for p56(lck) tyrosine kinase activation in T cell receptor-mediated thymic selection
13. Involvement of transcription factor TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus
14. CREB-binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites
15. Acetylation of general transcription factors by histone acetyltransferases
16. Fas(CD95)/FasL interaction required for programmed cell death after T-cell activation
17. + T cells in mice tolerant to Staphylococcus aureus enterotoxin B
18. Tumour necrosis factor and lymphotoxin: Molecular aspects and role in tissue-specific autoimmunity
19. Transcriptionlinked acetylation by GCN5p of histone H3 and H4 at specific lysines
20. Functional GATA-3 binding sites within murine CD8α upstream regulatory sequences
21. Characterization of cisregulatory elements and nuclear factors conferring Th2-specific expression of the IL-5 gene: A role for a GATA-binding protein
22. Transcriptional regulation of T cell receptor genes
23. Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements
24. p53 Site acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage
25. Antigen-specific development of primary and memory T cells in vivo
26. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity
27. The transcriptional coactivator p300 and CBP are histone acetyltransferase
28. Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis
29. Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism
30. Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment
31. Targeted disruption of the GATA-3 gene causes severe abnormalities in the nerve system and in fetal liver hematopoiesis
32. Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells
33. DNA damage activates p53 through a phosphorylation-acetylation cascade
34. Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts
35. Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements
36. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
37. GATA-3 dominant negative mutant. Functional redundancy of the T cell receptor α and β enhancers
38. Mouse interleukin-2 receptor α gene expression
39. Mouse interleukin-2 receptor α gene expression
40. Histone acetylation transcriptional regulator mechanisms
41. The common γ-chain for multiple cytokine receptors
42. The role of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice
43. Transcription factor GATA-3 is required for development of the T-cell lineage
44. Functional dissection of the murine lck distal promoter
45. Pathways leading to cell death in T cells
46. Elf-1 binds to a critical element in a second CD4 enhancer
47. Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins
48. Triple synergism of human T-lymphotropic virus type 1-encoded tax, GATA-binding protein and AP-1 is required for constitutive expression of the interleukin-5 gene in adult T-cell leukemia cells
49. Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interaction protein Tip60
50. A p300/CBP-associated factor that competes with the adenoviral oncoprotein Ela
51. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
52. Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3
53. Inhibition of allergic inflammation in a murine model of asthma by expressing of a dominant-negative mutant of GATA-3
54. Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activities by interaction with histone acetyltransferase
55. Induction of apoptosis in mature T cells by tumor necrosis factor
56. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells