메뉴 건너뛰기




Volumn 258, Issue 2, 2000, Pages 261-269

Induction of M-phase arrest and apoptosis after HIV-1 Vpr expression through uncoupling of nuclear and centrosomal cycle in HeLa cells

Author keywords

Apoptosis; Cell cycle; Centrosome; HIV; Vpr

Indexed keywords

VIRUS PROTEIN;

EID: 0034255815     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2000.4908     Document Type: Article
Times cited : (46)

References (56)
  • 1
    • 0024990404 scopus 로고
    • Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein
    • Yu X. F., Matsuda M., Essex M., Lee T. H. Open reading frame vpr of simian immunodeficiency virus encodes a virion-associated protein. J. Virol. 64:1990;5688-5693.
    • (1990) J. Virol. , vol.64 , pp. 5688-5693
    • Yu, X.F.1    Matsuda, M.2    Essex, M.3    Lee, T.H.4
  • 2
    • 0025295307 scopus 로고
    • Human immunodeficiency virus vpr product is a virion-associated regulatory protein
    • Cohen E. A., Dehni G., Sodroski J. G., Haseltine W. A. Human immunodeficiency virus vpr product is a virion-associated regulatory protein. J. Virol. 64:1990;3097-3099.
    • (1990) J. Virol. , vol.64 , pp. 3097-3099
    • Cohen, E.A.1    Dehni, G.2    Sodroski, J.G.3    Haseltine, W.A.4
  • 6
    • 0028987472 scopus 로고
    • The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles
    • Kondo E., Mammano F., Cohen E. A., Gottlinger H. G. The p6gag domain of human immunodeficiency virus type 1 is sufficient for the incorporation of Vpr into heterologous viral particles. J. Virol. 69:1995;2759-2764.
    • (1995) J. Virol. , vol.69 , pp. 2759-2764
    • Kondo, E.1    Mammano, F.2    Cohen, E.A.3    Gottlinger, H.G.4
  • 7
    • 0027429412 scopus 로고
    • Incorporation of Vpr into human immunodeficiency virus type 1 virions: Requirement for the p6 region of gag and mutational analysis
    • Paxton W., Connor R. I., Landau N. R. Incorporation of Vpr into human immunodeficiency virus type 1 virions: Requirement for the p6 region of gag and mutational analysis. J. Virol. 67:1993;7229-7237.
    • (1993) J. Virol. , vol.67 , pp. 7229-7237
    • Paxton, W.1    Connor, R.I.2    Landau, N.R.3
  • 8
    • 0028388662 scopus 로고
    • Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles
    • Lavallee C., Yao X. J., Ladha A., Gottlinger H., Haseltine W. A., Cohen E. A. Requirement of the Pr55gag precursor for incorporation of the Vpr product into human immunodeficiency virus type 1 viral particles. J. Virol. 68:1994;1926-1934.
    • (1994) J. Virol. , vol.68 , pp. 1926-1934
    • Lavallee, C.1    Yao, X.J.2    Ladha, A.3    Gottlinger, H.4    Haseltine, W.A.5    Cohen, E.A.6
  • 9
    • 0028800265 scopus 로고
    • A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles
    • Lu Y. L., Bennett R. P., Wills J. W., Gorelick R., Ratner L. A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles. J. Virol. 69:1995;6873-6879.
    • (1995) J. Virol. , vol.69 , pp. 6873-6879
    • Lu, Y.L.1    Bennett, R.P.2    Wills, J.W.3    Gorelick, R.4    Ratner, L.5
  • 10
    • 0028963445 scopus 로고
    • Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation
    • Mahalingam S., Khan S. A., Jabbar M. A., Monken C. E., Collman R. G., Srinivasan A. Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation. Virology. 207:1995;297-302.
    • (1995) Virology , vol.207 , pp. 297-302
    • Mahalingam, S.1    Khan, S.A.2    Jabbar, M.A.3    Monken, C.E.4    Collman, R.G.5    Srinivasan, A.6
  • 15
    • 0025017950 scopus 로고
    • The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages
    • Hattori N., Michaels F., Fargnoli K., Marcon L., Gallo R. C., Franchini G. The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages. Proc. Natl. Acad. Sci. USA. 87:1990;8080-8084.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8080-8084
    • Hattori, N.1    Michaels, F.2    Fargnoli, K.3    Marcon, L.4    Gallo, R.C.5    Franchini, G.6
  • 16
    • 0026655258 scopus 로고
    • Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants
    • Westervelt P., Henkel T., Trowbridge D. B., Orenstein J., Heuser J., Gendelman H. E., Ratner L. Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants. J. Virol. 66:1992;3925-3931.
    • (1992) J. Virol. , vol.66 , pp. 3925-3931
    • Westervelt, P.1    Henkel, T.2    Trowbridge, D.B.3    Orenstein, J.4    Heuser, J.5    Gendelman, H.E.6    Ratner, L.7
  • 17
    • 0027299295 scopus 로고
    • Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages
    • Balotta C., Lusso P., Crowley R., Gallo R. C., Franchini G. Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages. J. Virol. 67:1993;4409-4414.
    • (1993) J. Virol. , vol.67 , pp. 4409-4414
    • Balotta, C.1    Lusso, P.2    Crowley, R.3    Gallo, R.C.4    Franchini, G.5
  • 18
    • 0028297360 scopus 로고
    • Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: Mutational analysis of a primary HIV-1 isolate
    • Balliet J. W., Kolson D. L., Eiger G., Kim F. M., McGann K. A., Srinivasan A., Collman R. Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: Mutational analysis of a primary HIV-1 isolate. Virology. 200:1994;623-631.
    • (1994) Virology , vol.200 , pp. 623-631
    • Balliet, J.W.1    Kolson, D.L.2    Eiger, G.3    Kim, F.M.4    McGann, K.A.5    Srinivasan, A.6    Collman, R.7
  • 19
    • 0028842207 scopus 로고
    • Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
    • Connor R. I., Chen B. K., Choe S., Landau N. R. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology. 206:1995;935-944.
    • (1995) Virology , vol.206 , pp. 935-944
    • Connor, R.I.1    Chen, B.K.2    Choe, S.3    Landau, N.R.4
  • 20
    • 0030572623 scopus 로고    scopus 로고
    • The human immunodeficiency virus type 1 Vpr transactivator: Cooperation with promoter-bound activator domains and binding to TFIIB
    • Agostini I., Navarro J. M., Rey F., Bouhamdan M., Spire B., Vigne R., Sire J. The human immunodeficiency virus type 1 Vpr transactivator: Cooperation with promoter-bound activator domains and binding to TFIIB. J. Mol. Biol. 261:1996;599-606.
    • (1996) J. Mol. Biol. , vol.261 , pp. 599-606
    • Agostini, I.1    Navarro, J.M.2    Rey, F.3    Bouhamdan, M.4    Spire, B.5    Vigne, R.6    Sire, J.7
  • 22
    • 0028790642 scopus 로고
    • Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat
    • Wang L., Mukherjee S., Jia F., Narayan O., Zhao L. J. Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat. J. Biol. Chem. 270:1995;25564-25569.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25564-25569
    • Wang, L.1    Mukherjee, S.2    Jia, F.3    Narayan, O.4    Zhao, L.J.5
  • 23
    • 0028853961 scopus 로고
    • Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
    • He J., Choe S., Walker R., Di Marzio P., Morgan D. O., Landau N. R. Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity. J. Virol. 69:1995;6705-6711.
    • (1995) J. Virol. , vol.69 , pp. 6705-6711
    • He, J.1    Choe, S.2    Walker, R.3    Di Marzio, P.4    Morgan, D.O.5    Landau, N.R.6
  • 24
    • 0029165291 scopus 로고
    • The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle
    • Jowett J. B., Planelles V., Poon B., Shah N. P., Chen M. L., Chen I. S. The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle. J. Virol. 69:1995;6304-6313.
    • (1995) J. Virol. , vol.69 , pp. 6304-6313
    • Jowett, J.B.1    Planelles, V.2    Poon, B.3    Shah, N.P.4    Chen, M.L.5    Chen, I.S.6
  • 25
    • 0028801303 scopus 로고
    • Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B
    • Re F., Braaten D., Franke E. K., Luban J. Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B. J. Virol. 69:1995;6859-6864.
    • (1995) J. Virol. , vol.69 , pp. 6859-6864
    • Re, F.1    Braaten, D.2    Franke, E.K.3    Luban, J.4
  • 26
    • 0028813107 scopus 로고
    • The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection
    • Rogel M. E., Wu L. I., Emerman M. The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection. J. Virol. 69:1995;882-888.
    • (1995) J. Virol. , vol.69 , pp. 882-888
    • Rogel, M.E.1    Wu, L.I.2    Emerman, M.3
  • 27
    • 0029993519 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control
    • Bartz S. R., Rogel M. E., Emerman M. Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control. J. Virol. 70:1996;2324-2331.
    • (1996) J. Virol. , vol.70 , pp. 2324-2331
    • Bartz, S.R.1    Rogel, M.E.2    Emerman, M.3
  • 28
    • 0031950195 scopus 로고    scopus 로고
    • Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells
    • Yao X. J., Mouland A. J., Subbramanian R. A., Forget J., Rougeau N., Bergeron D., Cohen E. A. Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells. J. Virol. 72:1998;4686-4693.
    • (1998) J. Virol. , vol.72 , pp. 4686-4693
    • Yao, X.J.1    Mouland, A.J.2    Subbramanian, R.A.3    Forget, J.4    Rougeau, N.5    Bergeron, D.6    Cohen, E.A.7
  • 29
    • 0003124066 scopus 로고    scopus 로고
    • HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo
    • Goh W. C., Rogel M. E., Kinsey C. M., Michael S. F., Fultz P. N., Nowak M. A., Hahn B. H., Emerman M. HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo. Nature Med. 4:1998;65-71.
    • (1998) Nature Med. , vol.4 , pp. 65-71
    • Goh, W.C.1    Rogel, M.E.2    Kinsey, C.M.3    Michael, S.F.4    Fultz, P.N.5    Nowak, M.A.6    Hahn, B.H.7    Emerman, M.8
  • 30
    • 0030920243 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest
    • Stewart S. A., Poon B., Jowett J. B., Chen I. S. Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest. J. Virol. 71:1997;5579-5592.
    • (1997) J. Virol. , vol.71 , pp. 5579-5592
    • Stewart, S.A.1    Poon, B.2    Jowett, J.B.3    Chen, I.S.4
  • 31
    • 0031575854 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vpr gene product prevents cell proliferation on mouse NIH3T3 cells without the G2 arrest of the cell cycle
    • Nishino Y., Myojin T., Kamata M., Aida Y. Human immunodeficiency virus type 1 Vpr gene product prevents cell proliferation on mouse NIH3T3 cells without the G2 arrest of the cell cycle. Biochem. Biophys. Res. Commun. 232:1997;550-554.
    • (1997) Biochem. Biophys. Res. Commun. , vol.232 , pp. 550-554
    • Nishino, Y.1    Myojin, T.2    Kamata, M.3    Aida, Y.4
  • 32
    • 0029973558 scopus 로고    scopus 로고
    • Transcriptional activation of the syndecan-1 promoter by the Wilms' tumor protein WT1
    • Cook D. M., Hinkes M. T., Bernfield M., Rauscher F. J. III. Transcriptional activation of the syndecan-1 promoter by the Wilms' tumor protein WT1. Oncogene. 13:1996;1789-1799.
    • (1996) Oncogene , vol.13 , pp. 1789-1799
    • Cook, D.M.1    Hinkes, M.T.2    Bernfield, M.3    Rauscher F.J. III4
  • 33
    • 0029048491 scopus 로고
    • Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle
    • Watanabe N., Broome M., Hunter T. Regulation of the human WEE1Hu CDK tyrosine 15-kinase during the cell cycle. EMBO J. 14:1995;1878-1891.
    • (1995) EMBO J. , vol.14 , pp. 1878-1891
    • Watanabe, N.1    Broome, M.2    Hunter, T.3
  • 34
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi A., Gendelman H. E., Koenig S., Folks T., Willey R., Rabson A., Martin M. A. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59:1986;284-291.
    • (1986) J. Virol. , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6    Martin, M.A.7
  • 36
    • 0029063578 scopus 로고
    • Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): Failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1
    • Lusso P., Cocchi F., Balotta C., Markham P. D., Louie A., Farci P., Pal R., Gallo R. C., Reitz M. S. Jr. Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): Failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1. J. Virol. 69:1995;3712-3720.
    • (1995) J. Virol. , vol.69 , pp. 3712-3720
    • Lusso, P.1    Cocchi, F.2    Balotta, C.3    Markham, P.D.4    Louie, A.5    Farci, P.6    Pal, R.7    Gallo, R.C.8    Reitz M.S., Jr.9
  • 37
    • 0029016412 scopus 로고
    • Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors
    • Kumagai A., Dunphy W. G. Control of the Cdc2/cyclin B complex in Xenopus egg extracts arrested at a G2/M checkpoint with DNA synthesis inhibitors. Mol. Biol. Cell. 6:1995;199-213.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 199-213
    • Kumagai, A.1    Dunphy, W.G.2
  • 38
    • 0031930213 scopus 로고    scopus 로고
    • Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome
    • Mack G. J., Rees J., Sandblom O., Balczon R., Fritzler M. J., Rattner J. B. Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome. Arthritis Rheum. 41:1998;551-558.
    • (1998) Arthritis Rheum. , vol.41 , pp. 551-558
    • Mack, G.J.1    Rees, J.2    Sandblom, O.3    Balczon, R.4    Fritzler, M.J.5    Rattner, J.B.6
  • 39
    • 0029671272 scopus 로고    scopus 로고
    • Role of gamma-tubulin in mitosis-specific microtubule nucleation from the Schizosaccharomyces pombe spindle pole body
    • Masuda H., Shibata T. Role of gamma-tubulin in mitosis-specific microtubule nucleation from the Schizosaccharomyces pombe spindle pole body. J. Cell Sci. 109:1996;165-177.
    • (1996) J. Cell Sci. , vol.109 , pp. 165-177
    • Masuda, H.1    Shibata, T.2
  • 40
    • 0022830319 scopus 로고
    • Vectors for expression and amplification of cDNA in mammalian cells: Expression of rat phenylalanine hydroxylase
    • Choo K. H., Filby R. G., Jennings I. G., Peterson G., Fowler K. Vectors for expression and amplification of cDNA in mammalian cells: Expression of rat phenylalanine hydroxylase. DNA. 5:1986;529-537.
    • (1986) DNA , vol.5 , pp. 529-537
    • Choo, K.H.1    Filby, R.G.2    Jennings, I.G.3    Peterson, G.4    Fowler, K.5
  • 41
    • 0028824894 scopus 로고
    • Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr
    • Di Marzio P., Choe S., Ebright M., Knoblauch R., Landau N. R. Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr. J. Virol. 69:1995;7909-7916.
    • (1995) J. Virol. , vol.69 , pp. 7909-7916
    • Di Marzio, P.1    Choe, S.2    Ebright, M.3    Knoblauch, R.4    Landau, N.R.5
  • 42
    • 0030824787 scopus 로고    scopus 로고
    • Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr
    • Mahalingam S., Ayyavoo V., Patel M., Kieber-Emmons T., Weiner D. B. Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr. J. Virol. 71:1997;6339-6347.
    • (1997) J. Virol. , vol.71 , pp. 6339-6347
    • Mahalingam, S.1    Ayyavoo, V.2    Patel, M.3    Kieber-Emmons, T.4    Weiner, D.B.5
  • 43
    • 0027376064 scopus 로고
    • Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions
    • Lu Y. L., Spearman P., Ratner L. Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions. J. Virol. 67:1993;6542-6550.
    • (1993) J. Virol. , vol.67 , pp. 6542-6550
    • Lu, Y.L.1    Spearman, P.2    Ratner, L.3
  • 44
    • 0014250991 scopus 로고
    • The centriole cycle in synchronized HeLa cells
    • Robbins E., Jentzsch G., Micali A. The centriole cycle in synchronized HeLa cells. J. Cell Biol. 36:1968;329-339.
    • (1968) J. Cell Biol. , vol.36 , pp. 329-339
    • Robbins, E.1    Jentzsch, G.2    Micali, A.3
  • 45
    • 0020317988 scopus 로고
    • Centrioles in the cell cycle. I. Epithelial cells
    • Vorobjev I. A., Chentsov Yu S. Centrioles in the cell cycle. I. Epithelial cells. J. Cell Biol. 93:1982;938-949.
    • (1982) J. Cell Biol. , vol.93 , pp. 938-949
    • Vorobjev, I.A.1    Chentsov Yu, S.2
  • 46
    • 0030958826 scopus 로고    scopus 로고
    • Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest
    • Selig L., Benichou S., Rogel M. E., Wu L. I., Vodicka M. A., Sire J., Benarous R., Emerman M. Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest. J. Virol. 71:1997;4842-4846.
    • (1997) J. Virol. , vol.71 , pp. 4842-4846
    • Selig, L.1    Benichou, S.2    Rogel, M.E.3    Wu, L.I.4    Vodicka, M.A.5    Sire, J.6    Benarous, R.7    Emerman, M.8
  • 48
    • 0030951420 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard
    • Poon B., Jowett J. B., Stewart S. A., Armstrong R. W., Rishton G. M., Chen I. S. Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard. J. Virol. 71:1997;3961-3971.
    • (1997) J. Virol. , vol.71 , pp. 3961-3971
    • Poon, B.1    Jowett, J.B.2    Stewart, S.A.3    Armstrong, R.W.4    Rishton, G.M.5    Chen, I.S.6
  • 49
    • 0029027586 scopus 로고
    • Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells
    • Balczon R., Bao L., Zimmer W. E., Brown K., Zinkowski R. P., Brinkley B. R. Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells. J. Cell Biol. 130:1995;105-115.
    • (1995) J. Cell Biol. , vol.130 , pp. 105-115
    • Balczon, R.1    Bao, L.2    Zimmer, W.E.3    Brown, K.4    Zinkowski, R.P.5    Brinkley, B.R.6
  • 51
    • 0033525007 scopus 로고    scopus 로고
    • Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts [see comments]
    • Hinchcliffe E. H., Li C., Thompson E. A., Maller J. L., Sluder G. Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts [see comments]. Science. 283:1999;851-854.
    • (1999) Science , vol.283 , pp. 851-854
    • Hinchcliffe, E.H.1    Li, C.2    Thompson, E.A.3    Maller, J.L.4    Sluder, G.5
  • 52
    • 0033055061 scopus 로고    scopus 로고
    • Cyclin-dependent kinase control of centrosome duplication
    • Lacey K. R., Jackson P. K., Stearns T. Cyclin-dependent kinase control of centrosome duplication. Proc. Natl. Acad. Sci. USA. 96:1999;2817-2822.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2817-2822
    • Lacey, K.R.1    Jackson, P.K.2    Stearns, T.3
  • 53
    • 0029658664 scopus 로고    scopus 로고
    • Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage
    • Minn A. J., Boise L. H., Thompson C. B. Expression of Bcl-xL and loss of p53 can cooperate to overcome a cell cycle checkpoint induced by mitotic spindle damage. Genes Dev. 10:1996;2621-2631.
    • (1996) Genes Dev. , vol.10 , pp. 2621-2631
    • Minn, A.J.1    Boise, L.H.2    Thompson, C.B.3
  • 54
    • 0027410459 scopus 로고
    • Induction of cell differentiation by human immunodeficiency virus 1 vpr
    • Levy D. N., Fernandes L. S., Williams W. V., Weiner D. B. Induction of cell differentiation by human immunodeficiency virus 1 vpr. Cell. 72:1993;541-550.
    • (1993) Cell , vol.72 , pp. 541-550
    • Levy, D.N.1    Fernandes, L.S.2    Williams, W.V.3    Weiner, D.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.