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Journal of Molecular Graphics and Modelling

Volumn 18, Issue 4-5, 2000, Pages

Development and screening of a polyketide virtual library for drug leads against a motilide pharmacophore

(6) Siani, Michael A a Geoffrey Skillman, A b Carreras, Christopher W a Ashley, Gary a Kuntz, Irwin D b Santi, Daniel V a

a KOSAN BIOSCIENCES INC (United States)

b UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Macrolactone; Motilide; Polyketide; Virtual library; Virtual screening

Indexed keywords

GEOMETRY; LIBRARIES; MOLECULAR GRAPHICS; MOLECULES; SILICON; COMBINATORIAL MATHEMATICS; COMPUTER SYSTEMS PROGRAMMING; CONFORMATIONS; CONSTRAINT THEORY; DATABASE SYSTEMS; DRUG PRODUCTS;

VIRTUAL LIBRARIES;

DRUG THERAPY; MOLECULAR DYNAMICS;

6,9 ENOL ETHER ERYTHROMYCIN; ERYTHROMYCIN DERIVATIVE; MOTILIDE; MOTILIN; POLYKETIDE; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CALCULATION; CHEMICAL REACTION; COMBINATORIAL CHEMISTRY; CONFORMATIONAL TRANSITION; DRUG POTENCY; DRUG SCREENING; ENZYME MECHANISM; PHARMACOPHORE; PRIORITY JOURNAL; RECEPTOR BINDING;

MOTILIDE PHARMACOPHORES; POLYKETIDES;

EID: 0034240630 PISSN: 10933263 EISSN: None Source Type: Journal
DOI: 10.1016/S1093-3263(00)00070-X Document Type: Article

Times cited : (10)

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