Synthesis of 9-deoxo-4-deoxy-6,9-epoxyerythromycin derivatives: Novel and acid-stable motilides

Journal of Medicinal Chemistry

Volumn 41, Issue 18, 1998, Pages 3402-3408

  Faghih, Ramin ^a   Lartey, Paul A ^a,b   Nellans, Hugh N ^a   Seif, Louis ^a   Burnell Curty, Cynthia ^a   Klein, Larry L ^a   Thomas, Paul ^a   Petersen, Albert ^a   Borre, Anthony ^a   Pagano, Thomas ^a   Kim, Ki Hwan ^a   Heindel, Matthew ^a   Bennani, Youssef L ^a   Plattner, Jacob J ^a  

^a ABBOTT LABORATORIES   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

9 DEOXO 4'' DEOXY 3' N DESMETHYL 3' ETHYL 6,9 EPOXYEERYTHROMYCIN A; 9 DEOXO 4'' DEOXY 3' N DESMETHYL 3' N ETHANOL 6,9 EPOXYERYTHROMYCIN A; ALEMCINAL; ERYTHROMYCIN DERIVATIVE; MOTILIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; NONHUMAN; RABBIT;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG DESIGN; DRUG STABILITY; DUODENUM; ERYTHROMYCIN; ESCHERICHIA COLI; HYDROGEN-ION CONCENTRATION; MALE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PYLORIC ANTRUM; RABBITS; RECEPTORS, GASTROINTESTINAL HORMONE; RECEPTORS, NEUROPEPTIDE; STAPHYLOCOCCUS AUREUS; STEREOISOMERISM; STREPTOCOCCUS;

EID: 15444352574     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980022k     Document Type: Article

References (23)

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