Airway nitrogen oxide measurements in asthma and other pediatric respiratory diseases

Journal of Pediatrics

Volumn 137, Issue 1, 2000, Pages 14-20

  Hunt, John ^a   Gaston, Benjamin ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; ANTIINFLAMMATORY AGENT; CARBON MONOXIDE; HYDROXYLAMINE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; NITROGEN DERIVATIVE; NITROSO DERIVATIVE; NITROUS OXIDE; PEROXYNITRITE;

ACCURACY; ANATOMICAL VARIATION; ARTICLE; ASTHMA; BREATH ANALYSIS; CHEMOLUMINESCENCE; CONCENTRATION (PARAMETERS); DISEASE COURSE; EXPIRED AIR; HUMAN; LUNG FUNCTION TEST; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; STANDARDIZATION; WHEEZING;

EID: 0034234315     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1067/mpd.2000.107526     Document Type: Article

References (69)

1. Engesaeth V., Bush A., Kay A.B., Hamid Q., Corrigan C.J. Inhaled glucocorticoid therapy of childhood asthma is associated with reduced peripheral blood T cell activation and `Th2-type' cytokine mRNA expression. Pediatrics. 99:1997;695-703.
2. Kay A.B., Corrigan C.J., Frew A.J. The role of cellular immunology in asthma. Eur Respir J Suppl. 13:1991;105.
3. Bousquet J., Chanez P., Lacoste J.Y., Barneon G., Ghavanian N., Enander I. Eosinophilic inflammation in asthma. N Engl J Med. 323:1990;1033-1039.
4. Haahtela T., Jarvinen M., Kava T., Kiviranta K., Koskinen S., Lehtonen K. Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma. N Engl J Med. 325:1991;388-392.
5. Sears, MR, Taylor, DR, Print, CG, Lake, DC, Li, QQ, Flannery, EM1990Regular inhaled beta-agonist treatment in bronchial asthma.Lancet.
6. Spitzer W.O., Suissa S., Ernst P., Horwitz R.I., Habbick B., Cockcroft D. The use of beta-agonists and the risk of death and near death from asthma. N Engl J Med. 326:1992;501-506.
7. Ernst P., Habbick B., Suissa S., Hemmelgarn B., Cockcroft D., Buist A.S. Is the association between inhaled beta-agonist use and life-threatening asthma because of confounding by severity? Am Rev Respir Dis. 148:1993;75-79.
8. Haahtela, T, Jarvinen, M, Kava, T, Kiviranta, K, Koskinen, S, Lehtonen, K1994Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma.N Engl J Med.
9. Barnes P.J. Inhaled glucocorticoids for asthma. N Engl J Med. 332:1995;868-875.
10. Garrett J., Kolbe J., Richards G., Whitlock T., Rea H. Major reduction in asthma morbidity and continued reduction in asthma mortality in New Zealand: What lessons have been learned? Thorax. 50:1995;303-311.
11. National, Asthma, Education, Program, 1997, Expert Panel 2: Guidelines for the diagnosis and management of asthma. Washington (DC): US National Heart, Lung, and Blood Institute;
12. Hashimoto T., Minoguchi K., Kohno Y., Wada K., Ueno K., Kobayashi H. Correlation between respiratory function and airway inflammation in asthma. Int Arch Allergy Immunol. 120:1999;82-85.
13. Beasley R., Roche W.R., Roberts J.A., Holgate S.T. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am Rev Respir Dis. 139:1989;806-817.
14. Doull I.J., Freezer N.J., Holgate S.T. Growth of prepubertal children with mild asthma treated with inhaled beclomethasone dipropionate. Am J Respir Crit Care Med. 151:1995;1715-1719.
15. Klein R.B., Fritz G.K., Yeung A., McQuaid E.L., Mansell A. Spirometric patterns in childhood asthma: peak flow compared with other indices. Pediatr Pulmonol. 20:1995;372-379.
16. Gustafsson L.E., Leone A.M., Persson M.G., Wiklund N.P., Moncada S. Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans. Biochem Biophys Res Commun. 181:1991;852-857.
17. Artlich A., Hagenah J.U., Jonas S., Ahrens P., Gortner L. Exhaled nitric oxide in childhood asthma. Eur J Pediatr. 155:1996;698-701.
18. Nelson B.V., Sears S., Woods J., Ling C.Y., Hunt J., Clapper L.M. Expired nitric oxide as a marker for childhood asthma. J Pediatr. 130:1997;423-427.
19. Baraldi E., Azzolin N.M., Zanconato S., Dario C., Zacchello F. Corticosteroids decrease exhaled nitric oxide in children with acute asthma. J Pediatr. 131:1997;381-385.
20. Byrnes C.A., Dinarevic S., Shinebourne E.A., Barnes P.J., Bush A. Exhaled nitric oxide measurements in normal and asthmatic children. Pediatr Pulmonol. 24:1997;312-318.
21. Nathan C. Nitric oxide as a secretol product of mammalian cells. FASEB J. 6:1992;3051-3064.
22. Kobzik L., Bredt D.S., Lowenstein C.J., Drazen J., Gaston B., Sugarbaker D. Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. Am J Respir Cell Mol Biol. 9:1993;371-377.
23. De Sanctis G.T., MacLean J.A., Hamada K., Mehta S., Scott J.A., Jiao A. Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. J Exp Med. 189:1999;1621-1630.
24. Hamid Q., Springall D.R., Moreno V., Chanez P., Howarth P., Redington A. Induction of nitric oxide synthase in asthma. Lancet. 342:1993;1510-1513.
25. Klebanoff S.J. Reactive nitrogen intermediates and antimicrobial activity: role of nitrite. Free Radic Biol Med. 14:1993;351-360.
26. Koppenol W.H., Moreno J.J., Pryor W.A., Ischiropoulos H., Beckman J.S. Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide. Chem Res Toxicol. 5:1992;834-842.
27. Stamler J.S., Singel D.J., Loscalzo J. Biochemistry of nitric oxide and its redox-activated forms. Science. 258:1992;1898-1902.
28. Gaston B., Reilly J., Drazen J.M., Fackler J., Ramdev P., Arnelle D. Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways. Proc Natl Acad Sci USA. 90:1993;10957-10961.
29. Gow A.J., Luchsinger B.P., Pawloski J.R., Singel D.J., Stamler J.S. The oxyhemoglobin reaction of nitric oxide. Proc Natl Acad Sci USA. 96:1999;9027-9032.
30. Canady R.G., Mills T., Murphy A., Johannesen R., Gaston B. Vital capacity reservoir and online measurement of childhood nitrosopnea are linearly related. Clinical implications. Am J Respir Crit Care Med. 159:1999;311-314.
31. Massaro A.F., Gaston B., Kita D., Fanta C., Stamler J.S., Drazen J.M. Expired nitric oxide levels during treatment of acute asthma. Am J Respir Crit Care Med. 152:1995;800-803.
32. Kharitonov S., Alving K., Barnes P.J. Exhaled and nasal nitric oxide measurements: recommendations. The European Respiratory Society Task Force. Eur Respir J. 10:1997;1683-1693.
33. American Thoracic. Recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. Am J Respir Crit Care Med. 160:0417;210417.
34. Woods J., Sears S., Hunt J., Ling C., Strunc M., Gaston B. Plethysmographic measurement of airway nitric oxide production in cystic fibrosis and asthma [abstract]. Am J Respir Crit Care Med. 151:1995;747.
35. Baraldi E., Carra S., Dario C., Azzolin N., Ongaro R., Marcer G. Effect of natural grass pollen exposure on exhaled nitric oxide in asthmatic children. Am J Respir Crit Care Med. 159:1999;262-266.
36. Alving K., Weitzberg E., Lundberg J.M. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J. 6:1993;1368-1370.
37. Gaston B., Stamler J. Nitrogen oxides. In: Crystal RG, West JB, Barnes P, Weibel ER, editors. The lung: scientific foundations. 2nd ed. Philadelphia: Lippincott-Raven. 1997;239-253.
38. Dupont L.J., Rochette F., Demedts M.G., Verleden G.M. Exhaled nitric oxide correlates with airway hyperresponsiveness in steroid-naive patients with mild asthma. Am J Respir Crit Care Med. 157:1998;894-898.
39. Jatakanon A., Lira S., Kharitonov S.A., Chung K.F., Barnes P.J. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax. 53:1998;91-95.
40. Kanazawa H., Shoji S., Yamada M., Fujii T., Kawaguchi T., Kudoh S. Increased levels of nitric oxide derivatives in induced sputum in patients with asthma. J Allergy Clin Immunol. 99:1997;624-629.
41. Gratziou C., Lignos M., Dassiou M., Roussos C. Influence of atopy on exhaled nitric oxide in patients with stable asthma and rhinitis. Eur Respir J. 14:1999;897-901.
42. Kharitonov S.A., O'Connor B.J., Evans D.J., Barnes P.J. Allergen-induced late asthmatic reactions are associated with elevation of exhaled nitric oxide. Am J Respir Crit Care Med. 151:1995;1894-1899.
43. Guo F.H., Uetani K., Haque S.J., Williams B.R., Dweik R.A., Thunnissen F.B. Interferon gamma and interleukin 4 stimulate prolonged expression of inducible nitric oxide synthase in human airway epithelium through synthesis of soluble mediators. J Clin Invest. 100:1997;829-838.
44. Yates D.H., Kharitonov S.A., Thomas P.S., Barnes P.J. Endogenous nitric oxide is decreased in asthmatic patients by an inhibitor of inducible nitric oxide synthase. Am J Respir Crit Care Med. 154:1996;247-250.
45. Kharitonov S.A., Yates D.H., Barnes P.J. Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med. 153:1996;454-457.
46. Bisgaard H., Loland L., Oj J.A. NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast. Am J Respir Crit Care Med. 160:1999;1227-1231.
47. Grasemann H., Michler E., Wallot M., Ratjen F. Decreased concentration of exhaled nitric oxide (NO) in patients with cystic fibrosis. Pediatr Pulmonol. 24:1997;173-177.
48. Karadag B., James A.J., Gultekin E., Wilson N.M., Bush A. Nasal and lower airway level of nitric oxide in children with primary ciliary dyskinesia. Eur Respir J. 13:1999;1402-1405.
49. Xue C., Botkin S.J., Johns R.A. Localization of endothelial NOS at the basal microtubule membrane in ciliated epithelium of rat lung. J Histochem Cytochem. 44:1996;463-471.
50. Baraldi E., Dario C., Ongaro R., Scollo M., Azzolin N.M., Panza N. Exhaled nitric oxide concentrations during treatment of wheezing exacerbation in infants and young children. Am J Respir Crit Care Med. 159:1999;1284-1288.
51. Rolla G., Brussino L., Bertero M.T., Colagrande P., Converse M., Bucca C. Increased nitric oxide in exhaled air of patients with systemic lupus erythematosus. J Rheumatol. 24:1997;1066-1071.
52. Stewart T.E., Valenza F., Ribeiro S.P., Wener A.D., Volgyesi G., Mullen J.B. Increased nitric oxide in exhaled gas as an early marker of lung inflammation in a model of sepsis. Am J Respir Crit Care Med. 151:1995;713-718.
53. Mehta S., Javeshghani D., Datta P., Levv R.D., Magder S. Porcine endotoxemic shock is associated with increased expired nitric oxide. Crit Care Med. 27:1999;385-393.
54. Kharitonov S.A., Rajakulasingam K., O'Connor B., Durham S.R., Barnes P.J. Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids. J Allergy Clin Immunol. 99:1997;58-64.
55. Baraldi E., Azzolin N.M., Biban P., Zacchello F. Effect of antibiotic therapy on nasal nitric oxide concentration in children with acute sinusitis. Am J Respir Crit Care Med. 155:1997;1680-1683.
56. Mehta S., Lilly C.M., Rollenhagen J.E., Haley K.J., Asano K., Drazen J.M. Acute and chronic effects of allergic airway inflammation on pulmonary nitric oxide production. Am J Physiol. 272:1997;L124-31.
57. Hunt J., Fang K., Malik R., Snyder A., Malhotra N., Mills T. Endogenous airway acidification: implications for asthma pathophysiology. Am J Respir Crit Care Med. 161:2000;694-699.
58. Gaston B., Sears S., Woods J., Hunt J., Ponaman M., McMahon T. Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure. Lancet. 351:1998;1317-1319.
59. Zetterquist W., Pedroletti C., Lundberg J.O., Alving K. Salivary contribution to exhaled nitric oxide. Eur Respir J. 13:1999;327-333.
60. Vosswinkel R., Neidt I., Bothe H. The production and utilization of nitric oxide by a new, denitrifying strain of Pseudomonas aeruginosa. Arch Microbiol. 156:1991;62-69.
61. Hollocher T. The enzymology and occurrence of nitric oxide in the biological nitrogen cycle. In: Lancaster J, editor. Nitric oxide: principles and actions. San Diego: Academic Press. 1996;289-343.
62. Lundberg, JO, Weitzberg, E, Lundberg, JM, Alving, K1994Intragastric nitric oxide production in humans: measurements in expelled air.Gut.
63. Schedin U., Frostell C., Persson M.G., Jakobsson J. Andersson G, Gustafsson LE. Contribution from upper and lower airways to exhaled endogenous nitric oxide in humans. Acta Anaesthesiol Scand. 1995;39.
64. Gerlach H., Rossaim R., Pappert D., Knorr M., Falke K.J. Autoinhalation of nitric oxide after endogenous synthesis in nasopharynx. Lancet. 343:1994;518-519.
65. Schedin U., Norman M., Gustafsson L.E., Herin P., Frostell C. Endogenous nitric oxide in the upper airways of healthy newborn infants. Pediatr Res. 40:1996;148-151.
66. Massaro A.F., Mehta S., Lilly C.M., Kobzik L., Reilly J.J., Drazen J.M. Elevated nitric oxide concentrations in isolated lower airway gas of asthmatic subjects. Am J Respir Crit Care Med. 153:1996;1510-1514.
67. Silkoff, PE, McClean, PA, Slutsky, AS, Furlott, HG, Hoffstein, E, Wakita, S1997Marked flow-dependence of exhaled nitric oxide using a new technique to exclude nasal nitric oxide.Am J Respir Crit Care Med.
68. Hunt J., Byrns R.E., Ignarro L.J., Gaston B. Condensed expirate nitrite as a home marker for acute asthma [letter]. Lancet. 346:1995;1235-1236.
69. Zayasu K., Sekizawa K., Okinaga S., Yamaya M., Ohrui T., Sasaki H. Increased carbon monoxide in exhaled air of asthmatic patients. Am J Respir Crit Care Med. 156:1997;1140-1143.