Immortalization of rat embryo fibroblasts by a 3'-untranslated region

Experimental Cell Research

Volumn 240, Issue 2, 1998, Pages 252-262

  Powell, Andrew J ^a   Gates, Philip B ^a   Wylie, Diana ^a   Velloso, Cristiana P ^a   Brockes, Jeremy P ^b   Jat, Parmjit S ^b  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CELL PROLIFERATION; EMBRYO; FIBROBLAST; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; RAT; RNA SEQUENCE; SENESCENCE;

ANIMALIA; SALAMANDRIDAE;

EID: 0031874521     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.3937     Document Type: Article

References (68)

1. Campisi J. Replicative senescence: An old lives' tail. Cell. 84:1996;497-500.
2. Goldstein S. Replicative senescence: The human fibroblast comes of age. Science. 249:1990;1129-1133.
3. Hayflick L. The limitedin vitrolifetime of human diploid cell strains. Exp. Cell Res. 37:1965;614-636.
4. Hayflick L., Moorhead P. S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25:1961;585-621.
5. Tavassoli M., Shall S. Transcription of the c-myconcogene is altered in spontaneously immortalised rodent fibroblasts. Oncogene. 2:1988;337-345.
6. Gonos E. S., Burns J. S., Mazars G. R., Kobrna A., Riley T. G. W., Barnett S. C., Zafarana G., Ludwig R. L., Ikram Z., Powell A. J., Jat P. S. Rat embryo fibroblasts immortalized with SV40 T antigen undergo senescence upon its inactivation. Mol. Cell. Biol. 16:1996;5127-5138.
7. Ikram Z., Norton T., Jat P. S. The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen. Proc. Natl. Acad. Sci. USA. 91:1994;9448-9452.
8. Gonos E. S., Powell A. J., Jat P. S. Human and rodent fibroblasts: Model systems for studying senescence and immortalisation. Int. J. Oncol. 2:1992;209-213.
9. Curatolo L., Erba E., Morasca L. Culture conditions induce the appearance of immortalized C3H mouse cell lines. In Vitro. 20:1984;597-601.
10. Todaro G. J., Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established cell lines. J. Cell. Biol. 17:1963;299-313.
11. Harvey D. M., Levine A. J. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5:1991;2375-2385.
12. Rittling S. R., Denhardt D. T. p53 mutations in spontaneously immortalized 3T12 but not 3T3 mouse embryo cells. Oncogene. 7:1992;935-942.
13. Smith J. R., Pereira-Smith O. M. Genetic and molecular studies of cellular immortalization. Adv. Cancer Res. 54:1990;63-77.
14. Weinberg R. A. Cancer. 51:1983;1971-1975.
15. Shih C., Weinberg R. A. Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell. 29:1982;161-169.
16. Brockes J. P. Amphibian limb regeneration: Rebuilding a complex structure. Science. 276:1997;81-87.
17. Ferretti P., Brockes J. P. Culture of newt cells from different tissues and their expression of a regeneration-associated antigen. J. Exp. Zool. 247:1988;77-91.
18. Fekete D. M., Brockes J. P. A monoclonal antibody detects a difference in the cellular composition of developing and regenerating limbs of newts. Development. 99:1987;589-602.
19. Kintner C. R., Brockes J. P. Monoclonal antibodies to the cells of a regenerating limb. J. Embryol. Exp. Morphol. 89:1985;37-55.
20. Swirski R. A., Van Den Berg D., Murphy A. J. M., Lambert C. M., Friedberg E. C., Schimke R. T. Improvements in the Epstein-Barr-based shuttle vector system for direct cloning in human tissue culture cells. Methods Companion Methods Enzymol. 4:1992;133-142.
21. Blochlinger K., Duggerlmann H. Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eukaryotic cells. Mol. Cell. Biol. 4:1984;2929-2931.
22. Sambrook J., Fritsch E. F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
23. Ragsdale C. W., Petkovich M., Gates P., Chambon P., Brockes J. P. Identification of a novel retinoic acid receptor in regenerative tissue of the newt. Nature. 341:1989;654-657.
24. Casimir C. M., Gates P. B., Patient R. K., Brockes J. P. Evidence for dedifferentiation and metaplasia in amphibian limb regeneration from the inheritance of DNA methylation. Development. 104:1988;657-668.
25. Sauer B. Manipulation of transgenes by site-specific recombination: Use of Cre recombinase. Methods Enzymol. 225:1993;890-900.
26. Gorman C. M., Merlino G. T., Willingham M. C., Pastan I., Howard B. H. The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl. Acad. Sci. USA. 79:1982;6777-6781.
27. Ziff E. B. Transcription and RNA processing by the DNA tumour viruses. Nature. 287:1980;491-499.
28. Pipas J. M., Peden K. W. C., Nathans D. Mutational analysis of SV40 T antigen: Isolation and characterisation of mutants with deletions in the T-antigen gene. Mol. Cell. Biol. 3:1983;203-213.
29. Ewen M. E., Ludlow J. W., Marsilio E., DeCaprio J. A., Millikan R. C., Cheng S. H., Paucha E., Livingston D. M. An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110RB and a second cellular protein, p120. Cell. 58:1989;257-267.
30. Chen S., Paucha E. Identification of a region of simian virus 40 large T antigen required for cell transformation. J. Virol. 64:1990;3350-3357.
31. Thompson D. L., Kalderon D., Smith A. E., Tevethia M. J. Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing N-terminally truncated large T antigens. Virology. 178:1990;15-34.
32. Marsilio E., Cheng S. H., Schaffhausen B., Paucha E., Livingston D. M. The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence. J. Virol. 65:1991;5647-5652.
33. Kierstead T. D., Tevethia M. J. Association of p53 binding and immortalization of primary C57B1/6 mouse embryo fibroblasts by using simian virus 40 T antigen mutants bearing internal overlapping deletion mutations. J. Virol. 67:1993;1817-1829.
34. Conzen S. D., Cole C. N. The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts. Oncogene. 11:1995;2295-2302.
35. Anderson R. W., Tevethia M. J., Kalderon D., Smith A. E., Tevethia S. S. Fine mapping two distinct antigenic sites on simian virus 40 (SV40) T antigen reactive with SV40-specific cytotoxic T-cell clones by using deletion mutants. J. Virol. 62:1988;285-296.
36. Srinivasan A., McClellan A. J., Vartikar J., Marks I., Cantalupo P., Li Y., Whyte P., Rundell K., Brodsky J. L., Pipas J. M. The amino-terminal transforming region of simian virus 40 large T and small t functions as a J domain. Mol. Cell. Biol. 17:1997;4761-4773.
37. Jat P. S., Sharp P. A. Cell lines established by a temperature-sensitive SV40 large T antigen gene are growth restricted at the nonpermissive temperature. Mol. Cell. Biol. 9:1989;1672-1681.
38. Nomura N., Miyajima N., Sazuka T., Tanaka A., Kawarabayashi Y., Sato S., Nagase T., Seki T., Ishikawa K., Tabata S. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2:1995;37-43.
39. Lane D. P., Crawford L. V. T antigen is bound to a host protein in SV40-transformed cells. Nature. 278:1979;261-263.
40. Linzer D. I., Levine A. J. Characterisation of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell. 17:1979;43-52.
41. DeCaprio J. A., Ludlow J. W., Figge J., Shew J.-Y., Huang C.-M., Lee W.-H., Marsilio E., Paucha E., Livingston D. M. SV40 large T antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell. 54:1988;275-283.
42. Dyson N., Buchkovich K., Whyte P., Harlow E. The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell. 58:1989;249-255.
43. Campbell K. S., Mullane K., Aksoy I. A., Stubdal H., Zalvide J., Pipas J. M., Silver P. A., Roberts T. M., Schaffhausen B. S., DeCaprio J. A. DNAJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication. Genes Dev. 11:1997;1098-1110.
44. Symonds H. S., McCarthy S. A., Chen J., Pipas J. M., Van Dyke T. Use of transgenic mice reveals cell-specific transformation by a Simian virus 40 T-antigen amino-terminal mutant. Mol. Cell. Biol. 13:1993;3255-3265.
45. Yacuik P., Carter M. C., Pipas J. M., Moran E. Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products. Mol. Cell. Biol. 11:1991;2116-2124.
46. Lill N. L., Tevethia M. J., Eckner R., Livingston D. M., Modjtahedi N. p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen. J. Virol. 71:1997;129-137.
47. Porras A., Bennett J., Howe A., Tokos K., Bouck N., Hengein B., Sathyamangalam S., Thimmapaya B., Rundell K. A novel simian virus 40 early-region domain mediates transactivation of the cyclin A promoter by small t antigen and is required for transformation in small t antigen-dependent assays. J. Virol. 70:1996;6902-6908.
48. Lo D. C., Allen F., Brockes J. P. Reversal of muscle differentiation during urodele limb regeneration. Proc. Natl. Acad. Sci. USA. 90:1993;7230-7234.
49. Tanaka E. M., Gann A. A. F., Gates P. B., Brockes J. P. Newt myotubes re-enter the cell cycle by phosphorylation of the retinoblastoma protein. J. Cell Biol. 136:1997;155-165.
50. Decker C. J., Parker R. Diversity of cytoplasmic functions for the 3′ untranslated region of eucaryotic transcripts. Curr. Opin. Cell. Biol. 7:1995;386-392.
51. Brown B. D., Zipkin I. D., Harland R. M. Sequence-specific endonucleolytic cleavage and protection of mRNA inXenopusandDrosophila. Genes Dev. 7:1993;1620-1631.
52. Duret L., Dorkeld F., Gautier C. Strong conservation of non-coding sequences during vertebrates evolution: Potential involvement in post-transcriptional regulation of gene expression. Nucleic Acids Res. 21:1993;2315-2322.
53. Jackson R. J. Cytoplasmic regulation of mRNA function: The importance of the 3′ untranslated region. Cell. 74:1993;9-14.
54. Wilhelm J. E., Vale R. D. RNA on the move: The mRNA localization pathway. J. Cell Biol. 123:1993;269-274.
55. Curtis D., Lehmann R., Zamore P. D. Translational regulation in development. Cell. 81:1995;171-178.
56. Hentze M. W. Translational regulation: Versatile mechanisms for metabolic and developmental control. Curr. Opin. Cell Biol. 7:1995;393-398.
57. Vassalli J.-D., Stutz A. Awakening dormant mRNAs. Curr. Biol. 5:1995;476-479.
58. Dubnau J., Struhl G. RNA recognition and translational regulation by a homeodomain protein. Nature. 379:1996;694-699.
59. Rivera-Pomar R., Niessing D., Schmidt-Ott U., Gehring W. J., Jäckle H. RNA binding and translational suppression by bicoid. Nature. 379:1996;746-749.
60. Ahringer J., Kimble J. Control of the sperm-oocyte switch inCaenorhabditis eleganshermaphrodites by thefem33′ untranslated region. Nature. 349:1991;346-348.
61. Strickland S., Huarte J., Belin D., Vassalli A., Rickles R. J., Vassalli J.-D. Antisense RNA directed against the 3′ noncoding region prevents dormant mRNA activation in mouse oocytes. Science. 241:1988;680-684.
62. Khochbin S., Lawrence J.-J. An antisense RNA involved in p53 mRNA maturation in murine erythroleukemia cells induced to differentiate. EMBO J. 8:1989;4107-4114.
63. Sheets M. D., Fox C. A., Hunt T., Van de Woude G., Wickens M. The 3′-untranslated regions of c-mosand cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. Genes Dev. 8:1994;926-938.
64. Jupe E. R., Liu X. T., Kiehlbauch J. L., McClung J. K., Dell'Orco R. T. The 3′ untranslated region of prohibitin and cellular immortalization. Exp. Cell Res. 224:1996;128-135.
65. Rastinejad F., Blau H. M. Genetic complementation reveals a novel regulatory role for 3′ untranslated regions in growth and differentiation. Cell. 72:1993;903-917.
66. Rastinejad F., Conboy M. J., Rando T. A., Blau H. M. Tumor suppression by RNA from the 3′ untranslated region of α-tropomyosin. Cell. 75:1993;1107-1117.
67. L'Ecuyer T. J., Tompach P. C., Morris E., Fulton A. B. Transdifferentiation of chicken embryonic cells into muscle cells by the 3′ untranslated region of muscle tropomyosin. Proc. Natl. Acad. Sci. USA. 92:1995;7520-7524.
68. Enoch T., Zinn K., Maniatis T. Activation of the human β-interferon gene requires an interferon-inducible factor. Mol. Cell. Biol. 6:1986;801-810.