Selected Th1 and Th2 cytokine mRNA expression by CD4+ T cells isolated from inflamed human gingival tissues

Clinical and Experimental Immunology

Volumn 103, Issue 3, 1996, Pages 422-428

  Fujihashi, K ^a   Yamamoto, M ^a   Hiroi, T ^b   Bamberg, T V ^a   Mcghee, J R ^a   Kiyono, H ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Cytokines gingival; Inflammation; Th1 and Th2; Tissues

Indexed keywords

CD4 ANTIGEN; CYTOKINE; MESSENGER RNA;

ADULT; ARTICLE; CLINICAL ARTICLE; FLOW CYTOMETRY; GINGIVITIS; HELPER CELL; HUMAN; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0029873756     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.1996.tb08297.x     Document Type: Article

References (39)

1. Mosmann TR, Cherwinski H, Bond MW et al. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-57.
2. Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7:145-73.
3. Romagnani S. Human Th1 and Th2 subsets: doubt no more. Immunol Today 1991; 12:256-7.
4. Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994; 12:227-57.
5. Wierenga EA, Snoek M, deGroot C et al. Evidence for compartmentalization of functional subsets of CD2 T lymphocytes in atopic patients. J Immunol 1990; 144:4651-6.
6. Del Prete GK, DeCarli M, Mastromauro C et al. Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production. J Clin Invest 1991; 8:346-50.
7. Parronchi P, Macchia D, Piccinni MP et al. Allergen-and bacterial antigen-specific T cell clones established from atopic donors show a different profile of cytokine production. Proc Natl Acad Sci USA 1991; 88:4538-42.
8. Yamamura M, Uyemura K, Deans RJ et al. Defining protective responses to pathogens: cytokine profiles in leprosy lesions. Science 1991; 254:277-9.
9. Yssel H, Shanafelt MC, Soderberg C et al. Borrelia burgdorferi activates a T helper type 1 like T cell subset in Lyme arthritis. J Exp Med; 174:593-601.
10. Schlaak J, Hermann E, Ringhoffer M et al. Predominance of Th1-type T cells in synovial fluid of patients with Yersinia-induced reactive arthritis. Eur J Immunol 1992; 22:2771-6.
11. Lahesmaa R, Yssel H, Batsford S et al. Yersinia enterocoliticia activates a T helper type 1 like T cell subset in reactive arthritis. J Immunol 1992; 148:3079-85.
12. Socransky SS, Haffajee AD. The bacterial etiology of destructive periodonlal disease: current concepts. J Periodontol 1992; 63:322-31.
13. Williams RC. Periodontal disease. New Eng J Med 1990; 322:373-82.
14. Okada H, Kida T, Yamagami H. Identification and distribution of immunocompetent cells in inflamed gingiva of human chronic periodontitis. Infect Immun 1983; 41:365-74.
15. Taubman MA, Stoufi ED, Ebersole JL et al. Phenotypic studies of cells from periodontal disease tissues. J Periodontal Res 1984; 19:587-90.
16. Seymour GJ. Possible mechanisms involved in the immunoregulation of chronic inflammatory periodontal disease. J Dent Res 1987; 66:2-9.
17. McGhee ML, Ogawa T, Pitts AM et al. Cellular analysis of functional mononuclcar cells from chronically inflamed gingival tissue. Reg Immunol 1989; 2:103-10.
18. Genco RJ, Mashimo PA, Kreggier G et al. Antibody-mediated effects on the periodontium. J Periodontol 1977; 45:330-7.
19. Mackler BE, Frostad KB, Robertson PB et al. Immunoglobulin bearing lymphocytes and plasma cells in human periodontal disease. J Periodontol Res 1977; 12:37-45.
20. Ogawa T, Tarkowski A, McGhee ML et al. Analysis of human IgG and IgA subclass antibody-secreting cells from localized chronic inflammatory tissue. J Immunol 1989; 142:1150-8.
21. Kono Y, Beagley KW, Fujinashi K et al. Cytokine regulation of localized inflammation. Induction of activated B cells and IL-6 mediated polyclonal IgG and IgA synthesis in inflamed human gingiva. J Immunol 1991; 146:1812-21.
22. Matsuki Y, Yamamoto T, Hara K. Detection of inflammatory cytokine messenger RNA (mRNA)-expressing cells in human inflamed gingiva by combined in situ hybridization and immunohistochemistry. Immunology 1992; 76:42-47.
23. Gemmell E, Seymour GJ. Interleukin-1, interleukin-6 and transforming growth factor-β production by human gingival mononuclear cells following stimulation with Porphyromonas gingivalis and Fusobacterium nucleatum. J Periodont Res 1993; 28:122-9.
24. Fujihashi K, Beagley KW, Kono Y et al. Gingival mononuclear cells from chronic inflammatory periodontal tissues produce interleukin (IL)-5 and IL-6 but not IL-2 and IL-4. Amer J Pathol 1993; 142:1239-50.
25. Lundqvist C, Baranov V, Teglund S et al. Cytokine profile and ultrastructure of intraepithelial γδ T cells in chronically inflamed human gingiva suggest a cytotoxic effector function. J Immunol 1994; 153:2302-12.
26. Brenner CA, Tam AW, Nelson PA et al. Message amplification phenotyping (MAPPing): a technique to simultaneously measure multiple mRNAs from small numbers of cells. Biotechniques 1989; 7:1096-103.
27. Yamamoto M, Fujihashi K, Beagley KW et al. Cytokine synthesis by intestinal intraepithelial lymphocytes. Both γ/δ T cell receptor-positive and α/b T cell receptor-positive T cells in the G1 phase of cell cycle produce IFN-γ and IL-5. J Immunol 1993; 150:106-14.
28. Chomczynski P, Sacchi N. Single-step method of RNA isolation of acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-9.
29. Stoufi ED, Taubman MA, Ebersole JL et al. Phenotype analyses of mononuclear cells recovered from healthy and diseased human periodontal tissues. J Clin Immunol 1987; 7:235-45.
30. Lundqvist C, Hammarström ML. T-cell receptor γδ-expressing intraepithelial lymphocytes are present in normal and chronically inflamed human gingiva. Immunology 1993; 79:38-45.
31. Becker S. Interferons as modulators of human monocyte macrophage differentiation. I. Interferon-gamma increases HLA-DR expression and inhibits phagocytosis of zymosan. J Immunol 1984; 132:1249-54.
32. Mangan DF, Robertson B, Wahl SW. IL-4 enhances programmed cell death (apoptosis) in stimulated human monocytes. J Immunol 1992; 148:1812-6.
33. Zurawski G, deVries JE. Interleukin-13, an interleukin-4-like cytokine that acts on monocytes and B cells, but not on T cells. Immunol Today 1994; 15:19-26.
34. Punnonen J, Aversa G, Cocks BG et al. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 1993; 90: 3730-4.
35. Minty A, Chalon P, Derocq JM et al. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 1993; 362:248-50.
36. Moore KW, O'Garra A, de Waal Malefyt R et al. Interleukin 10. Annu Rev Immunol 1993; 11:165-90.
37. Taga K, Tosato G. IL-10inhibits human Tcell proliferation and IL-2 production. J Immunol 1992; 148:1143-8.
38. Del Prete GF, De Carli M, Almerigogna F et al. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 1993; 150:353-60.
39. de Waal Malefyt R, Abrams J, Bennett B et al. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991; 174:1209-20.