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Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 361, Issue 5, 2000, Pages 555-564

Cloning, expression, functional coupling and pharmacological characterization of the rat dopamine D4 receptor

(6) Gazi, Lucien a Schoeffter, Philippe a Nunn, Caroline a Croskery, Kim a Hoyer, Daniel a Feuerbach, Dominik a

a NOVARTIS PHARMA AG (Switzerland)

Author keywords

35S GTP S; cAMP; Dopamine; Extracellular acidification; Rat brain; Rat dopamine D4 receptor; Signal transduction

Indexed keywords

1,2,3,4,4A,5,10,10A OCTAHYDRO 6 HYDROXY 1 METHYL 3 [(2 PYRIDYLTHIO)METHYL]BENZO[G]QUINOLINE; 2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 2 PHENYL 4 [4 (2 PYRIMIDINYL) 1 PIPERAZINYLMETHYL]IMIDAZOLE; 3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; APOMORPHINE; CLOZAPINE; DOPAMINE; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; FORSKOLIN; HALOPERIDOL; N (1 BENZYL 4 PIPERIDINYL) N (3 ISOPROPOXY 2 PYRIDINYL) N METHYLAMINE; PD 168077; PERTUSSIS TOXIN; QUINPIROLE; RACLOPRIDE; SPIPERONE; UNCLASSIFIED DRUG;

ACIDIFICATION; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; CHINESE HAMSTER; CONCENTRATION RESPONSE; DRUG RECEPTOR BINDING; LUNG FIBROBLAST; MOLECULAR CLONING; NONHUMAN; RAT; RECEPTOR AFFINITY; RETINA; SECOND MESSENGER; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; BINDING, COMPETITIVE; CALCIUM; CELLS, CULTURED; CLONING, MOLECULAR; CRICETINAE; CYCLIC AMP; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DOPAMINE; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; DRUG INTERACTIONS; FORSKOLIN; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; INOSITOL PHOSPHATES; NUCLEAR PROTEINS; PERTUSSIS TOXIN; RATS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; SERUM RESPONSE FACTOR; SPIPERONE; SULFUR RADIOISOTOPES; TRANSFECTION; TRITIUM; VIRULENCE FACTORS, BORDETELLA;

EID: 0034117368 PISSN: 00281298 EISSN: None Source Type: Journal
DOI: 10.1007/s002100000236 Document Type: Article

Times cited : (21)

References (38)

1
- 0027931519
- 4 receptor repeat: Analysis of different native and mutant forms of the human and rat genes
- 4 receptor repeat: analysis of different native and mutant forms of the human and rat genes. Mol Pharmacol 46:364-373
- (1994) Mol Pharmacol , vol.46 , pp. 364-373
- Asghari, V.¹ Schoots, O.² Van Kats, S.³ Ohara, K.⁴ Jovanovic, V.⁵ Guan, H.C.⁶ Bunzow, J.R.⁷ Petronis, A.⁸ Van Tol, H.H.M.⁹

2
- 0028238523
- 4 receptors
- 4 receptors. J Neurochem 63:62-65
- (1994) J Neurochem , vol.63 , pp. 62-65
- Chabert, C.¹ Cavegn, C.² Bernard, A.³ Mills, A.⁴

3
- 0028364257
- D4 dopamine receptor-mediated signaling events determined in transfected chinese hamster ovary cells
- Chio CL, Drong RF, Riley DT, Gill GS, Slightom JL, Huff RM (1994) D4 dopamine receptor-mediated signaling events determined in transfected Chinese hamster ovary cells. J Biol Chem 269:11813-11819
- (1994) J Biol Chem , vol.269 , pp. 11813-11819
- Chio, C.L.¹ Drong, R.F.² Riley, D.T.³ Gill, G.S.⁴ Slightom, J.L.⁵ Huff, R.M.⁶

4
- 0027102748
- 4 receptors coupled to adenylate cyclase
- 4 receptors coupled to adenylate cyclase. Proc Natl Acad Sci USA 89:12093-12097
- (1992) Proc Natl Acad Sci USA , vol.89 , pp. 12093-12097
- Cohen, A.¹ Todd, R.² Harmon, S.³ O'Malley, K.⁴

5
- 0032773336
- 44 receptors expressed in Chinese hamster ovary cells
- 44 receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 127: 1135-1144
- (1999) Br J Pharmacol , vol.127 , pp. 1135-1144
- Coldwell, M.C.¹ Boyfield, I.² Brown, A.M.³ Stemp, G.⁴ Middlemiss, D.N.⁵

6
- 0031128072
- 4 dopamine receptor in rat brain with sequence-specific antibodies
- 4 dopamine receptor in rat brain with sequence-specific antibodies. Brain Res Mol Brain Res 45:1-12
- (1997) Brain Res Mol Brain Res , vol.45 , pp. 1-12
- Defagot, M.C.¹ Malchiodi, E.L.² Villar, M.J.³ Antonelli, M.C.⁴

7
- 0031024896
- Establishment and characterization of conditionally immortalized stromal cell lines from a temperature-sensitive T-Ag transgenic mouse
- Feuerbach D, Loetscher E, Buerki K, Sampath TK, Feyen JH (1997) Establishment and characterization of conditionally immortalized stromal cell lines from a temperature-sensitive T-Ag transgenic mouse. J Bone Miner Res 12:179-190
- (1997) J Bone Miner Res , vol.12 , pp. 179-190
- Feuerbach, D.¹ Loetscher, E.² Buerki, K.³ Sampath, T.K.⁴ Feyen, J.H.⁵

8
- 0029976759
- 2long dopamine receptors expressed in recombinant cells
- 2long dopamine receptors expressed in recombinant cells. Br J Pharmacol 118:1544-1550
- (1996) Br J Pharmacol , vol.118 , pp. 1544-1550
- Gardner, B.¹ Hall, D.A.² Strange, P.G.³

9
- 0030613814
- 2(short) dopamine receptors determined in ligand binding and functional assays
- 2(short) dopamine receptors determined in ligand binding and functional assays. J Neurochem 69:2589-2598
- (1997) J Neurochem , vol.69 , pp. 2589-2598
- Gardner, B.¹ Hall, D.A.² Strange, P.G.³

10
- 7144264386
- 4-4 receptor
- 4-4 receptor. Br J Pharmacol 124:889-896
- (1998) Br J Pharmacol , vol.124 , pp. 889-896
- Gazi, L.¹ Bobirnac, M.² Danzeisen, M.³ Schüpbach, E.⁴ Bruinvels, A.⁵ Geisse, S.⁶ Hoyer, D.⁷ Tricklebank, M.⁸ Schoeffter, P.⁹

11
- 0033020790
- 4.4 receptors expressed in HEK293 cells
- 4.4 receptors expressed in HEK293 cells. Eur J Pharmacol 372:R9-R10
- (1999) Eur J Pharmacol , vol.372
- Gazi, L.¹ Sommer, B.² Nozulak, J.³ Schoeffter, P.⁴

12
- 0032701195
- 4-4 receptors expressed in CHO cells
- 4-4 receptors expressed in CHO cells. Br J Pharmacol 128:613-620
- (1999) Br J Pharmacol , vol.128 , pp. 613-620
- Gazi, L.¹ Bobirnac, M.² Danzeisen, M.³ Schüpbach, E.⁴ Langenegger, D.⁵ Sommer, B.⁶ Tricklebank, M.⁷ Schoeffter, P.⁸

13
- 0030961684
- Substituted [(4-phenylpiperazinyl)-methyl]benzamides: Selective dopamine D4 agonists
- Glase SA, Akunne HC, Georgic LM, Heffner TG, MacKenzie RG, Manley PJ, Pugsley TA, Wise LD (1997) Substituted [(4-phenylpiperazinyl)-methyl]benzamides: selective dopamine D4 agonists. J Med Chem 40:1771-1772
- (1997) J Med Chem , vol.40 , pp. 1771-1772
- Glase, S.A.¹ Akunne, H.C.² Georgic, L.M.³ Heffner, T.G.⁴ MacKenzie, R.G.⁵ Manley, P.J.⁶ Pugsley, T.A.⁷ Wise, L.D.⁸

14
- 0027936755
- A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
- Han J, Lee JD, Bibbs L, Ulevitch RJ (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811
- (1994) Science , vol.265 , pp. 808-811
- Han, J.¹ Lee, J.D.² Bibbs, L.³ Ulevitch, R.J.⁴

15
- 0024997935
- pp54 Microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine
- Kyriakis JM, Avruch J (1990) pp54 microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine. J Biol Chem 265:17355-17363
- (1990) J Biol Chem , vol.265 , pp. 17355-17363
- Kyriakis, J.M.¹ Avruch, J.²

16
- 0029658699
- D2-type dopamine receptors in postmortem human brain sections from normal and schizophrenic subjects
- Lahti RA, Roberts RC, Conley RR, Cochrane EV, Mutin A, Tamminga CA (1996) D2-type dopamine receptors in postmortem human brain sections from normal and schizophrenic subjects. Neuroreport 7:1945-1948
- (1996) Neuroreport , vol.7 , pp. 1945-1948
- Lahti, R.A.¹ Roberts, R.C.² Conley, R.R.³ Cochrane, E.V.⁴ Mutin, A.⁵ Tamminga, C.A.⁶

17
- 0029044125
- 4 dopamine receptors determined in transfected cell lines
- 4 dopamine receptors determined in transfected cell lines. Clin Neuropharmacol 18:S25-S33
- (1995) Clin Neuropharmacol , vol.18
- Lajisness, M.E.¹ Chio, C.L.² Huff, R.M.³

18
- 0027314352
- 4 (DRD4) gene
- 4 (DRD4) gene. Hum Mol Genet 2:767-773
- (1993) Hum Mol Genet , vol.2 , pp. 767-773
- Lichter, J.B.¹ Barr, C.L.² Kennedy, J.L.³ Van, T.H.⁴ Kidd, K.K.⁵ Livak, K.J.⁶

19
- 0029863250
- 2 receptors
- 2 receptors. J Neural Transm 103:17-30
- (1996) J Neural Transm , vol.103 , pp. 17-30
- Markstein, R.¹ Gull, P.² Rüdeberg, C.³ Urwyler, S.⁴ Jaton, A.⁵ Kalkman, H.⁶ Dixon, A.⁷ Hoyer, D.⁸

20
- 0028872649
- Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
- Marshall CJ (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185
- (1995) Cell , vol.80 , pp. 179-185
- Marshall, C.J.¹

21
- 0028965905
- 4 dopamine receptors in postmortem striatum from patients with schizophrenia
- 4 dopamine receptors in postmortem striatum from patients with schizophrenia. J Neurosci 15:2186-2191
- (1995) J Neurosci , vol.15 , pp. 2186-2191
- Murray, A.M.¹ Hyde, T.M.² Knable, M.B.³ Herman, M.M.⁴ Bigelow, L.B.⁵ Carter, J.M.⁶ Weinberger, D.R.⁷ Kleinman, J.E.⁸

22
- 0030610721
- 4.4 receptors: Actions of antiparkinsonian and antipsychotic agents
- 4.4 receptors: actions of antiparkinsonian and antipsychotic agents. J Pharmacol Exp Ther 282:181-191
- (1997) J Pharmacol Exp Ther , vol.282 , pp. 181-191
- Newman-Tancredi, A.¹ Audinot, V.² Chaput, C.³ Verrièle, L.⁴ Millan, M.J.⁵

23
- 0026810697
- 4 receptor: Sequence, gene structure, and demonstration of expression in the cardiovascular system
- 4 receptor: sequence, gene structure, and demonstration of expression in the cardiovascular system. New Biologist 4:137-146
- (1992) New Biologist , vol.4 , pp. 137-146
- O'Malley, K.L.¹ Harmon, S.² Tang, L.³ Todd, R.D.⁴

24
- 9844254480
- Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor
- Patel S, Freedman S, Chapman KL, Emms F, Fletcher AE, Knowles M, Marwood R, Mcallister G, Myers J, Curtis N, Kulagowski JJ, Leeson PD, Ridgill M, Graham M, Matheson S, Rathbone D, Watt AP, Bristow LJ, Rupniak NM, Baskin E, Lynch JJ, Ragan CI (1997) Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor. J Pharmacol Exp Ther 283:636-647
- (1997) J Pharmacol Exp Ther , vol.283 , pp. 636-647
- Patel, S.¹ Freedman, S.² Chapman, K.L.³ Emms, F.⁴ Fletcher, A.E.⁵ Knowles, M.⁶ Marwood, R.⁷ Mcallister, G.⁸ Myers, J.⁹ Curtis, N.¹⁰ Kulagowski, J.J.¹¹ Leeson, P.D.¹² Ridgill, M.¹³ Graham, M.¹⁴ Matheson, S.¹⁵ Rathbone, D.¹⁶ Watt, A.P.¹⁷ Bristow, L.J.¹⁸ Rupniak, N.M.¹⁹ Baskin, E.²⁰ Lynch, J.J.²¹ Ragan, C.I.²² more..

25
- 0030610861
- 1B/D receptor ligands: An answer from GTPγS binding studies with stably transfected C6-glial cell lines
- 1B/D receptor ligands: an answer from GTPγS binding studies with stably transfected C6-glial cell lines. Neuropharmacology 36:499-512
- (1997) Neuropharmacology , vol.36 , pp. 499-512
- Pauwels, P.J.¹ Tardif, S.² Palmier, C.³ Wurch, T.⁴ Colpaert, F.C.⁵

26
- 0029665512
- The importance of dopamine D4 receptors in the action and development of antipsychotic agents
- Reynolds GP (1996) The importance of dopamine D4 receptors in the action and development of antipsychotic agents. Drugs 51:7-11
- (1996) Drugs , vol.51 , pp. 7-11
- Reynolds, G.P.¹

27
- 0029078512
- 4 receptors in drug-treated schizophrenia
- 4 receptors in drug-treated schizophrenia. Eur J Pharmacol 281:R5-R6
- (1995) Eur J Pharmacol , vol.281
- Reynolds, G.P.¹ Mason, S.L.²

28
- 0025801402
- 3H]cAMP in cell monolayers, cell suspensions, and tissue slices
- 3H]cAMP in cell monolayers, cell suspensions, and tissue slices. Methods Enzymol 195:22-28
- (1991) Methods Enzymol , vol.195 , pp. 22-28
- Salomon, Y.¹

29
- 0030941646
- 4 receptor
- 4 receptor. Eur J Pharmacol 322:283-286
- (1997) Eur J Pharmacol , vol.322 , pp. 283-286
- Schlachter, S.K.¹ Poel, T.J.² Lawson, C.F.³ Dinh, D.M.⁴ Lajiness, M.E.⁵ Romero, A.G.⁶ Rees, S.A.⁷ Duncan, J.N.⁸ Smith, M.W.⁹

30
- 0028809985
- 125I]epidepride
- 125I]epidepride. Eur J Pharmacol 286:R3-R5
- (1995) Eur J Pharmacol , vol.286
- Seeman, P.¹ Guan, H.C.² Van, T.H.³

31
- 0030950434
- 3H]benzquinoline
- 3H]benzquinoline. Synapse 25:137-146
- (1997) Synapse , vol.25 , pp. 137-146
- Seeman, P.¹ Guan, H.C.² Nobrega, J.³ Jiwa, D.⁴ Markstein, R.⁵ Balk, J.H.⁶ Picetti, R.⁷ Borrelli, E.⁸ Van Tol, H.H.M.⁹

32
- 0033010348
- 4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia
- 4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia. Mol Psychiatry 4:235-246
- (1999) Mol Psychiatry , vol.4 , pp. 235-246
- Sharma, A.¹ Kramer, M.L.² Wick, P.F.³ Liu, D.⁴ Chari, S.⁵ Shim, S.⁶ Tan, W.⁷ Ouellette, D.⁸ Nagata, M.⁹ DuRand, C.J.¹⁰ Kotb, M.¹¹ Deth, R.C.¹²

33
- 0028978359
- 3H]raclopride binding in postmortem caudate nucleus of subjects with schizophrenia or major depression
- 3H]raclopride binding in postmortem caudate nucleus of subjects with schizophrenia or major depression. Brain Res 681:109-116
- (1995) Brain Res , vol.681 , pp. 109-116
- Sumiyoshi, T.¹ Stockmeier, C.A.² Overholser, J.C.³ Thompson, P.A.⁴ Meltzer, H.Y.⁵

34
- 0030743501
- 4 receptor
- 4 receptor. J Pharmacol Exp Ther 282: 1011-1019
- (1997) J Pharmacol Exp Ther , vol.282 , pp. 1011-1019
- Tallman, J.F.¹ Primus, R.J.² Brodbeck, R.³ Cornfield, L.⁴ Meade, R.⁵ Woodruff, K.⁶ Ross, P.⁷ Thurkauf, A.⁸ Gallagher, D.W.⁹

35
- 0028147691
- 4 dopamine receptors in fibroblast and dopaminergic cell lines
- 4 dopamine receptors in fibroblast and dopaminergic cell lines. J Pharmacol Exp Ther 268:495-502
- (1994) J Pharmacol Exp Ther , vol.268 , pp. 495-502
- Tang, L.¹ Todd, R.D.² Heller, A.³ O'Malley, K.L.⁴

36
- 0026427253
- 4 receptor with high affinity for the antipsychotic clozapine
- 4 receptor with high affinity for the antipsychotic clozapine. Nature 350:610-614
- (1991) Nature , vol.350 , pp. 610-614
- Van Tol, H.H.¹ Bunzow, J.R.² Guan, H.C.³ Sunahara, R.K.⁴ Seeman, P.⁵ Niznik, H.B.⁶ Civelli, O.⁷

37
- 0026651968
- 4 receptor variants in the human population
- 4 receptor variants in the human population. Nature 358:149-152
- (1992) Nature , vol.358 , pp. 149-152
- Van Tol, H.H.¹ Wu, C.M.² Guan, H.C.³ Ohara, K.⁴ Bunzow, J.R.⁵ Civelli, O.⁶ Kennedy, J.⁷ Seeman, P.⁸ Niznik, H.B.⁹ Jovanovic, V.¹⁰

38
- 0030611164
- αt2) to inhibit forskolin-stimulated cAMP accumulation
- αt2) to inhibit forskolin-stimulated cAMP accumulation. J Biol Chem 272:16599-16602
- (1997) J Biol Chem , vol.272 , pp. 16599-16602
- Yamaguchi, I.¹ Harmon, S.K.² Todd, R.D.³ O'Malley, K.L.⁴

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