메뉴 건너뛰기




Volumn 69, Issue 6, 1997, Pages 2589-2598

Agonist action at D(2(short)) dopamine receptors determined in ligand binding and functional assays

Author keywords

Agonist action; Cyclic AMP accumulation; Dopamine D2 receptor; G protein; Ligand binding; Ternary complex; 35S Guanosine 5' O (3 thiotriphosphate) binding

Indexed keywords

APOMORPHINE; BROMOCRIPTINE; CYCLIC AMP; DIHYDROERGOCRISTINE; DOPAMINE; DOPAMINE 2 RECEPTOR; DOPAMINE 2 RECEPTOR STIMULATING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE TRIPHOSPHATE; PRECLAMOL; PROPYLNORAPOMORPHINE; QUINPIROLE; DOPAMINE RECEPTOR STIMULATING AGENT; LIGAND; SPIPERONE;

EID: 0030613814     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69062589.x     Document Type: Article
Times cited : (37)

References (30)
  • 1
    • 0021712818 scopus 로고
    • Catecholamine-stimulated guanosine 5′-O-(3-thiotriphosphate) binding to stimulatory GTP binding protein of adenylyl cyclase: Kinetic analysis in reconstituted phospholipid vesicles
    • Asano T. and Ross E. M. (1984) Catecholamine-stimulated guanosine 5′-O-(3-thiotriphosphate) binding to stimulatory GTP binding protein of adenylyl cyclase: kinetic analysis in reconstituted phospholipid vesicles. Biochemistry 23, 5467-5471.
    • (1984) Biochemistry , vol.23 , pp. 5467-5471
    • Asano, T.1    Ross, E.M.2
  • 2
    • 0027534185 scopus 로고
    • Differences in the ligand binding properties of the long and short versions of the D2 dopamine receptor
    • Castro S. and Strange P. G. (1993) Differences in the ligand binding properties of the long and short versions of the D2 dopamine receptor. J. Neurochem. 60, 372-375.
    • (1993) J. Neurochem. , vol.60 , pp. 372-375
    • Castro, S.1    Strange, P.G.2
  • 3
    • 0028012102 scopus 로고
    • Activation of heterologously expressed D3 dopamine receptors: Comparison with D2 dopamine receptors
    • Chio C. L., Lajiness M. E., and Huff R. M. (1994) Activation of heterologously expressed D3 dopamine receptors: comparison with D2 dopamine receptors. Mol. Pharmacol. 54, 51-60.
    • (1994) Mol. Pharmacol. , vol.54 , pp. 51-60
    • Chio, C.L.1    Lajiness, M.E.2    Huff, R.M.3
  • 5
    • 0019137579 scopus 로고
    • A ternary complex model explains the agonist specific binding properties of the adenylyl cyclase coupled β-adrenergic receptor
    • De Lean A., Stadel J. M., and Lefkowitz R. J. (1980) A ternary complex model explains the agonist specific binding properties of the adenylyl cyclase coupled β-adrenergic receptor. J. Biol. Chem. 255, 7108-7117.
    • (1980) J. Biol. Chem. , vol.255 , pp. 7108-7117
    • De Lean, A.1    Stadel, J.M.2    Lefkowitz, R.J.3
  • 6
    • 0029976759 scopus 로고    scopus 로고
    • 35S]GTPγS binding via human D2short and D2long dopamine receptors expressed in recombinant cells
    • 35S]GTPγS binding via human D2short and D2long dopamine receptors expressed in recombinant cells. Br. J. Pharmacol. 118, 1544-1550.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1544-1550
    • Gardner, B.R.1    Hall, D.A.2    Strange, P.G.3
  • 7
    • 0023062991 scopus 로고
    • G-proteins: Transducers of receptor generated signals
    • Gilman A. G. (1987) G-proteins: transducers of receptor generated signals. Annu. Rev. Biochem. 56, 615-649.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 8
    • 0029148651 scopus 로고
    • Relationship between inhibition of cyclic AMP production in Chinese hamster ovary cells expressing the rat D2(444) receptor and antagonist/agonist binding ratios
    • Harley E. A., Middlemiss D. M., and Ragan C. I. (1995) Relationship between inhibition of cyclic AMP production in Chinese hamster ovary cells expressing the rat D2(444) receptor and antagonist/agonist binding ratios. Br. J. Pharmacol 115, 1307-1313.
    • (1995) Br. J. Pharmacol , vol.115 , pp. 1307-1313
    • Harley, E.A.1    Middlemiss, D.M.2    Ragan, C.I.3
  • 10
    • 0026695537 scopus 로고
    • Structural subtypes of the dopamine D2 receptor are functionally distinct: Expression of the cloned D2A and D2B subtypes in a heterologous cell line
    • Hayes G., Biden T. J., Selbie L. A., and Shine J. (1992) Structural subtypes of the dopamine D2 receptor are functionally distinct: expression of the cloned D2A and D2B subtypes in a heterologous cell line. Mol. Endocrinol. 6, 920-926.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 920-926
    • Hayes, G.1    Biden, T.J.2    Selbie, L.A.3    Shine, J.4
  • 11
    • 0027424642 scopus 로고
    • The disaggregation theory of signal transduction revisited: Further evidence that G-protems are multimeric and disaggregate to monomers when activated
    • Jahangeer S. and Rodbell M. (1993) The disaggregation theory of signal transduction revisited: further evidence that G-protems are multimeric and disaggregate to monomers when activated. Proc. Natl. Acad. Sci. USA 90, 8782-8786.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8782-8786
    • Jahangeer, S.1    Rodbell, M.2
  • 13
    • 0027049395 scopus 로고
    • Intrinsic activity determinations at the dopamine D2 guanine nucleotide binding protein coupled receptor. Utilisation of receptor state binding affinities
    • Lahti R. A., Figur L. M., Piercey M. F., Ruppel P. L., and Evans D. L. (1992) Intrinsic activity determinations at the dopamine D2 guanine nucleotide binding protein coupled receptor. Utilisation of receptor state binding affinities. Mol. Pharmacol. 42, 432-438.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 432-438
    • Lahti, R.A.1    Figur, L.M.2    Piercey, M.F.3    Ruppel, P.L.4    Evans, D.L.5
  • 14
    • 0023017887 scopus 로고
    • Assessment of a ternary model for the binding of agonists to neurohumoral receptors
    • Lee T. W. T., Sole M. J., and Wells J. W. (1986) Assessment of a ternary model for the binding of agonists to neurohumoral receptors. Biochemistry 25, 7009-7020.
    • (1986) Biochemistry , vol.25 , pp. 7009-7020
    • Lee, T.W.T.1    Sole, M.J.2    Wells, J.W.3
  • 15
    • 0027297275 scopus 로고
    • Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins
    • Lefkowitz R. J., Cotecchia S., Samama P., and Costa T. (1993) Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends Pharmacol. Sci. 14, 303-307.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 303-307
    • Lefkowitz, R.J.1    Cotecchia, S.2    Samama, P.3    Costa, T.4
  • 16
    • 0023893103 scopus 로고
    • Mechanisms of agonist and antagonist binding to α2 adrenergic receptors: Evidence for a precoupled receptor-guanine nucleotide protein complex
    • Neubig R. R., Gantzos R. D., and Thomsen W. J. (1988) Mechanisms of agonist and antagonist binding to α2 adrenergic receptors: evidence for a precoupled receptor-guanine nucleotide protein complex. Biochemistry 27, 2374-2384.
    • (1988) Biochemistry , vol.27 , pp. 2374-2384
    • Neubig, R.R.1    Gantzos, R.D.2    Thomsen, W.J.3
  • 18
    • 0029665131 scopus 로고    scopus 로고
    • D2 receptor agonists and partial agonists: Relationship between receptor binding measures and functional activity
    • O'Boyle K.M. and Lawlor M. (1996) D2 receptor agonists and partial agonists: relationship between receptor binding measures and functional activity. Biochem. Soc. Trans. 24, 183-188.
    • (1996) Biochem. Soc. Trans. , vol.24 , pp. 183-188
    • O'Boyle, K.M.1    Lawlor, M.2
  • 19
    • 0024709982 scopus 로고
    • Signal sorting and amplification through G protein coupled receptors
    • Ross E. M. (1989) Signal sorting and amplification through G protein coupled receptors. Neuron 3, 141-152.
    • (1989) Neuron , vol.3 , pp. 141-152
    • Ross, E.M.1
  • 20
    • 0016374975 scopus 로고
    • A highly sensitive adenylate cyclase assay
    • Salomon Y., Londos C., and Rodbell M. (1974) A highly sensitive adenylate cyclase assay. Anal. Biochem. 58, 541-548.
    • (1974) Anal. Biochem. , vol.58 , pp. 541-548
    • Salomon, Y.1    Londos, C.2    Rodbell, M.3
  • 22
    • 0020597636 scopus 로고
    • Interaction of ergot alkaloids with anterior pituitary D2 dopamine receptors
    • Sibley D. R. and Creese I. (1983) Interaction of ergot alkaloids with anterior pituitary D2 dopamine receptors. Mol. Pharmacol. 23, 585-593.
    • (1983) Mol. Pharmacol. , vol.23 , pp. 585-593
    • Sibley, D.R.1    Creese, I.2
  • 23
    • 1842291805 scopus 로고
    • Molecular biology of dopamine receptors
    • Sibley D. R. and Monsma F. J. (1992) Molecular biology of dopamine receptors. Trends Pharmacol. Sci. 15, 264-270.
    • (1992) Trends Pharmacol. Sci. , vol.15 , pp. 264-270
    • Sibley, D.R.1    Monsma, F.J.2
  • 24
    • 0027583723 scopus 로고
    • 3H histamine in guinea pig cerebral cortex; mechanistic basis for multiple states of affinity
    • 3H histamine in guinea pig cerebral cortex; mechanistic basis for multiple states of affinity. Mol. Pharmacol. 43, 583-594.
    • (1993) Mol. Pharmacol. , vol.43 , pp. 583-594
    • Sinkins, W.G.1    Wells, J.A.2
  • 25
    • 0028856362 scopus 로고
    • 3H]lisuride labels free receptor and receptor coupled to G protein
    • 3H]lisuride labels free receptor and receptor coupled to G protein. J. Neurochem. 65, 1909-1916.
    • (1995) J. Neurochem. , vol.65 , pp. 1909-1916
    • Sundaram, H.1    Turner, J.D.2    Strange, P.G.3
  • 26
    • 0024596455 scopus 로고
    • Mechanisms of signal transduction at the D2 dopamine receptor
    • Vallar L. and Meldolesi J. (1989) Mechanisms of signal transduction at the D2 dopamine receptor. Trends Pharmacol. Sci. 10, 74-77.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 74-77
    • Vallar, L.1    Meldolesi, J.2
  • 27
    • 0028337644 scopus 로고
    • Deletion analysis of the m4 muscarinic receptor. Molecular determinants for activation of but not coupling to guanine nucleotide binding regulatory protein regulate receptor internalisation
    • Van Koppen C. J., Sell H., Lenz W., and Jakobs K. H. (1994) Deletion analysis of the m4 muscarinic receptor. Molecular determinants for activation of but not coupling to guanine nucleotide binding regulatory protein regulate receptor internalisation. Eur. J. Biochem. 222, 525-531.
    • (1994) Eur. J. Biochem. , vol.222 , pp. 525-531
    • Van Koppen, C.J.1    Sell, H.2    Lenz, W.3    Jakobs, K.H.4
  • 28
    • 0023668517 scopus 로고
    • Alkylation of the bovine anterior pituitary D2 dopamine receptor: Inconsistency with the predictions of the ternary complex model
    • Wreggett K. A. (1987) Alkylation of the bovine anterior pituitary D2 dopamine receptor: inconsistency with the predictions of the ternary complex model. Biochem. Biophys. Res. Commun. 147, 1070-1076.
    • (1987) Biochem. Biophys. Res. Commun. , vol.147 , pp. 1070-1076
    • Wreggett, K.A.1
  • 29
    • 0021697164 scopus 로고
    • The ternary complex model: Its properties and applications to ligand interactions with the D2 dopamine receptor of the anterior pituitary gland
    • Wreggett K. A. and De Lean A. (1984) The ternary complex model: its properties and applications to ligand interactions with the D2 dopamine receptor of the anterior pituitary gland. Mol. Pharmacol. 26, 214-227.
    • (1984) Mol. Pharmacol. , vol.26 , pp. 214-227
    • Wreggett, K.A.1    De Lean, A.2
  • 30
    • 0029083945 scopus 로고
    • Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors
    • Wreggett K. A. and Wells J. A. (1995) Cooperativity manifest in the binding properties of purified cardiac muscarinic receptors. J. Biol. Chem. 270, 22488-22499.
    • (1995) J. Biol. Chem. , vol.270 , pp. 22488-22499
    • Wreggett, K.A.1    Wells, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.