메뉴 건너뛰기




Volumn 14, Issue 4, 2000, Pages 327-332

Mechanisms of alcoholic liver injury

Author keywords

Cytokines; Ethanol; Growth factors; Kupffer cells; Stellate cells

Indexed keywords

CYTOKINE; ENDOTOXIN; NEOMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; PHOSPHATASE; PROTEASOME; PROTEIN KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SATURATED FATTY ACID; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UBIQUITIN;

EID: 0034103739     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/2000/801735     Document Type: Review
Times cited : (46)

References (67)
  • 1
    • 0029123422 scopus 로고
    • Cellular signals in alcohol-induced liver injury: A review
    • Lands WFM. Cellular signals in alcohol-induced liver injury: A review. Alcohol Clin Exp Res 1995;19:928-38.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 928-938
    • Lands, W.F.M.1
  • 3
    • 0028220726 scopus 로고
    • Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver disease
    • Nanji A, Khettry U, Sadrzadeh S. Lactobacillus feeding reduces endotoxemia and severity of experimental alcoholic liver disease. Proc Soc Exp Biol 1994;205:243-7.
    • (1994) Proc Soc Exp Biol , vol.205 , pp. 243-247
    • Nanji, A.1    Khettry, U.2    Sadrzadeh, S.3
  • 4
    • 0028796860 scopus 로고
    • Antibiotics prevent liver injury in rats following long-term exposure to ethanol
    • Adachi Y, Moore L, Bradford B, Thurman R. Antibiotics prevent liver injury in rats following long-term exposure to ethanol. Gastroenterology 1995;108:218-24.
    • (1995) Gastroenterology , vol.108 , pp. 218-224
    • Adachi, Y.1    Moore, L.2    Bradford, B.3    Thurman, R.4
  • 5
    • 0028108372 scopus 로고
    • Inactivation of Kupffer cells prevents early alcohol-induced liver injury
    • Adachi Y, Bradford B, Gao W, Thurman R. Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 1994;20:453-60.
    • (1994) Hepatology , vol.20 , pp. 453-460
    • Adachi, Y.1    Bradford, B.2    Gao, W.3    Thurman, R.4
  • 8
    • 0028236896 scopus 로고
    • Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods
    • Nanji AA, Zhao S, Sadrzadeh SM. Use of reverse transcription-polymerase chain reaction to evaluate in vivo cytokine gene expression in rats fed ethanol for long periods. Hepatology 1994;19:1483-7.
    • (1994) Hepatology , vol.19 , pp. 1483-1487
    • Nanji, A.A.1    Zhao, S.2    Sadrzadeh, S.M.3
  • 9
    • 0029121402 scopus 로고
    • Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease
    • Kaminura S, Tsukamoto H. Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease. Hepatology 1995;21:1304-9.
    • (1995) Hepatology , vol.21 , pp. 1304-1309
    • Kaminura, S.1    Tsukamoto, H.2
  • 10
    • 0030716183 scopus 로고    scopus 로고
    • Antibodies to tumor necrosis factor alpha attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
    • Imuro Y, Gallucci R, Luster ML, Kano H, Thurman RG. Antibodies to tumor necrosis factor alpha attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat. Hepatology 1997;26:1530-7.
    • (1997) Hepatology , vol.26 , pp. 1530-1537
    • Imuro, Y.1    Gallucci, R.2    Luster, M.L.3    Kano, H.4    Thurman, R.G.5
  • 11
    • 12944276835 scopus 로고    scopus 로고
    • Development of a new enterai mouse model using knock out technology to study alcohol-induced liver injury: Involvement of TNFα
    • Abst
    • Yin M, Kono H, Bradford BU, Thurman RO. Development of a new enterai mouse model using knock out technology to study alcohol-induced liver injury: involvement of TNFα. Hepatology 1998;28:321. (Abst)
    • (1998) Hepatology , vol.28 , pp. 321
    • Yin, M.1    Kono, H.2    Bradford, B.U.3    Thurman, R.O.4
  • 12
    • 27844509597 scopus 로고    scopus 로고
    • The intracellular signaling network as a target for ethanol
    • Hoek JB, Kholodenko BN. The intracellular signaling network as a target for ethanol. Alcohol Clin Exp Res 1998;22:224S-30S.
    • (1998) Alcohol Clin Exp Res , vol.22
    • Hoek, J.B.1    Kholodenko, B.N.2
  • 13
    • 0031059248 scopus 로고    scopus 로고
    • Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat
    • Nanji AA, Miao L, Thomas P, et al. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat. Gastroenterology 1997;112:943-51.
    • (1997) Gastroenterology , vol.112 , pp. 943-951
    • Nanji, A.A.1    Miao, L.2    Thomas, P.3
  • 14
    • 0031928131 scopus 로고    scopus 로고
    • Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin
    • Enomoto N, Ikejima K, Bradford B, et al. Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin. Gastroenterology 1998;115:443-51.
    • (1998) Gastroenterology , vol.115 , pp. 443-451
    • Enomoto, N.1    Ikejima, K.2    Bradford, B.3
  • 16
    • 12944286303 scopus 로고    scopus 로고
    • Increased acetaldehyde in vivo inhibits NFκB activation through IKBα preservation and ameliorates liver injury in experimental alcoholic liver disease
    • Abst
    • Jokelainen K, Lindros KO, Nanji AA. Increased acetaldehyde in vivo inhibits NFκB activation through IKBα preservation and ameliorates liver injury in experimental alcoholic liver disease. Hepatology 1998;28:499. (Abst)
    • (1998) Hepatology , vol.28 , pp. 499
    • Jokelainen, K.1    Lindros, K.O.2    Nanji, A.A.3
  • 17
    • 0029160569 scopus 로고
    • Experimental liver cirrhosis induced by alcohol and iron
    • Tsukamoto H, Home W, Kamimura S, et al. Experimental liver cirrhosis induced by alcohol and iron. J Clin Invest 1995;96:620-30.
    • (1995) J Clin Invest , vol.96 , pp. 620-630
    • Tsukamoto, H.1    Home, W.2    Kamimura, S.3
  • 18
    • 0029129182 scopus 로고
    • Apoptosis and Bcl-2 protein expression in experimental alcoholic liver disease in the rat
    • Yacoub LK, Fogt F, Geriniuviene B, Nanji AA. Apoptosis and Bcl-2 protein expression in experimental alcoholic liver disease in the rat. Alcohol Clin Exp Res 1995;19:854-9.
    • (1995) Alcohol Clin Exp Res , vol.19 , pp. 854-859
    • Yacoub, L.K.1    Fogt, F.2    Geriniuviene, B.3    Nanji, A.A.4
  • 20
    • 0030782177 scopus 로고    scopus 로고
    • Cytochrome C: Can't live with it - Can't live without it
    • Reed JC. Cytochrome C: Can't live with it - can't live without it. Cell 1997;91:559-62.
    • (1997) Cell , vol.91 , pp. 559-562
    • Reed, J.C.1
  • 21
  • 22
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity
    • Fromenty B, Pessayre D. Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity. Pharmacol Ther 1995;67:101-54.
    • (1995) Pharmacol Ther , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 23
    • 85056568841 scopus 로고    scopus 로고
    • Lipid peroxidation, CYP2E1 and fatty acid metabolism in alcoholic liver disease
    • French SW, Morimoto M, Reitz R, et al. Lipid peroxidation, CYP2E1 and fatty acid metabolism in alcoholic liver disease. J Nutr 1997;127:9075-115.
    • (1997) J Nutr , vol.127 , pp. 9075-9115
    • French, S.W.1    Morimoto, M.2    Reitz, R.3
  • 24
    • 0030045690 scopus 로고    scopus 로고
    • Role of cytochrome P450 2E1-dependent formation of hydroxyethyl free radicals in the development of liver damage in rats intragastrically fed with ethanol
    • Albano E, Clot P, Morimoto M, Tamasi A, Ingelman-Sundberg M, French SW. Role of cytochrome P450 2E1-dependent formation of hydroxyethyl free radicals in the development of liver damage in rats intragastrically fed with ethanol. Hepatology 1996;23:155-63.
    • (1996) Hepatology , vol.23 , pp. 155-163
    • Albano, E.1    Clot, P.2    Morimoto, M.3    Tamasi, A.4    Ingelman-Sundberg, M.5    French, S.W.6
  • 25
    • 12944257081 scopus 로고    scopus 로고
    • Cytochrome P450 2E1, hydroxyethyl free radicals and immune reactions associated to alcoholic liver disease
    • Albano E, French SW, Ingelman-Sundberg M. Cytochrome P450 2E1, hydroxyethyl free radicals and immune reactions associated to alcoholic liver disease. Alcohol Clin Exp Res 1998;22:739-42.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 739-742
    • Albano, E.1    French, S.W.2    Ingelman-Sundberg, M.3
  • 26
    • 0031966327 scopus 로고    scopus 로고
    • P450-dependent metabolism of lauric acid in alcoholic liver disease: Comparison between rat liver and kidney microsomes
    • Amet Y, Lucas D, Zhang-Gouillon ZQ, French SW. P450-dependent metabolism of lauric acid in alcoholic liver disease: comparison between rat liver and kidney microsomes. Alcohol Clin Exp Res 1998;22:455-62.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 455-462
    • Amet, Y.1    Lucas, D.2    Zhang-Gouillon, Z.Q.3    French, S.W.4
  • 27
    • 12944289445 scopus 로고    scopus 로고
    • Alcohol-inducible P450 in rat liver and kidney microsomes. Fatty acid metabolism
    • Amet Y, Berthou F, French SW. Alcohol-inducible P450 in rat liver and kidney microsomes. Fatty acid metabolism. Alcohol Clin Exp Res 1998;22:744-6.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 744-746
    • Amet, Y.1    Berthou, F.2    French, S.W.3
  • 28
    • 0032981322 scopus 로고    scopus 로고
    • Autoantibodies against cytochromes P-4502E1 and P-4503A in alcoholics
    • Lytton SD, Helander A, Zhang-Gouillon ZQ, et al. Autoantibodies against cytochromes P-4502E1 and P-4503A in alcoholics. Mol Pharmacol 1999;55:223-33.
    • (1999) Mol Pharmacol , vol.55 , pp. 223-233
    • Lytton, S.D.1    Helander, A.2    Zhang-Gouillon, Z.Q.3
  • 29
    • 0030988742 scopus 로고    scopus 로고
    • Biochemistry and pathology of radical-mediated protein oxidation
    • Dean RT, Fu S, Stocker R, Davies MJ. Biochemistry and pathology of radical-mediated protein oxidation. Biochem J 1997;324:1-18.
    • (1997) Biochem J , vol.324 , pp. 1-18
    • Dean, R.T.1    Fu, S.2    Stocker, R.3    Davies, M.J.4
  • 30
    • 12944263496 scopus 로고    scopus 로고
    • Effects of DB-cAMP on ubiquitin and CYP2E1 levels in experimental ethanol-induced liver disease
    • Abst
    • Zhang-Gouillon ZQ, Yuan QX, French BA, et al. Effects of DB-cAMP on ubiquitin and CYP2E1 levels in experimental ethanol-induced liver disease. Hepatology 1996;24:442. (Abst)
    • (1996) Hepatology , vol.24 , pp. 442
    • Zhang-Gouillon, Z.Q.1    Yuan, Q.X.2    French, B.A.3
  • 31
    • 17344368193 scopus 로고    scopus 로고
    • Peptidase activities of the multicatalytic protease in rat liver after voluntary and intragastric ethanol administration
    • Donohue TM Jr, Zetterman RK, Zhang-Gouillon ZQ, French SW. Peptidase activities of the multicatalytic protease in rat liver after voluntary and intragastric ethanol administration. Hepatology 1998;28:486-91.
    • (1998) Hepatology , vol.28 , pp. 486-491
    • Donohue Jr., T.M.1    Zetterman, R.K.2    Zhang-Gouillon, Z.Q.3    French, S.W.4
  • 32
    • 0030982143 scopus 로고    scopus 로고
    • Degradation of oxidized proteins in mammalian cells
    • Grune T, Reinheckel T, Davies KJA. Degradation of oxidized proteins in mammalian cells. FASEB J 1997;11:526-34.
    • (1997) FASEB J , vol.11 , pp. 526-534
    • Grune, T.1    Reinheckel, T.2    Davies, K.J.A.3
  • 33
    • 0029093010 scopus 로고
    • Oxidation of mitochondrial proteins and DNA following administration of ethanol
    • Wieland P, Lauterburg BH. Oxidation of mitochondrial proteins and DNA following administration of ethanol. Biochem Biophys Res Commun 1995;213:815-9.
    • (1995) Biochem Biophys Res Commun , vol.213 , pp. 815-819
    • Wieland, P.1    Lauterburg, B.H.2
  • 34
    • 0028836808 scopus 로고
    • Hepatic mitochondrial DNA deletion in alcoholics: Association microvesicular steatosis
    • Fromenty B, Grimbe TS, Mansowie A, et al Hepatic mitochondrial DNA deletion in alcoholics: association microvesicular steatosis. Gastroenterology 1995;108:193-200.
    • (1995) Gastroenterology , vol.108 , pp. 193-200
    • Fromenty, B.1    Grimbe, T.S.2    Mansowie, A.3
  • 35
    • 0030806434 scopus 로고    scopus 로고
    • Multiple hepatic DNA deletions suggest premature oxidative aging in alcoholics
    • Mansowi A, Fromenty B, Berson A, et al. Multiple hepatic DNA deletions suggest premature oxidative aging in alcoholics. J Hepatol 1997;27:96-102.
    • (1997) J Hepatol , vol.27 , pp. 96-102
    • Mansowi, A.1    Fromenty, B.2    Berson, A.3
  • 37
    • 0030989910 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatic fibrosis and principles of therapy
    • Friedman SL. Molecular mechanisms of hepatic fibrosis and principles of therapy. J Gastroenterology 1997;32:424-30.
    • (1997) J Gastroenterology , vol.32 , pp. 424-430
    • Friedman, S.L.1
  • 38
    • 0028596335 scopus 로고
    • Expression of variant fibronectins in wound healing. Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis
    • Janagen WR, Rockey DC, Koteliansk VE, Wang SS, Bissell DM. Expression of variant fibronectins in wound healing. Cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J Cell Biol 1994;127:2037-48.
    • (1994) J Cell Biol , vol.127 , pp. 2037-2048
    • Janagen, W.R.1    Rockey, D.C.2    Koteliansk, V.E.3    Wang, S.S.4    Bissell, D.M.5
  • 39
    • 0030838746 scopus 로고    scopus 로고
    • Deposition of cellular fibronectin increases before stellate activation in rat liver during ethanol feeding
    • Gillis SE, Nagy LE. Deposition of cellular fibronectin increases before stellate activation in rat liver during ethanol feeding. Alcohol Clin Exp 1997;21:857-61.
    • (1997) Alcohol Clin Exp , vol.21 , pp. 857-861
    • Gillis, S.E.1    Nagy, L.E.2
  • 40
    • 0027869670 scopus 로고
    • Studies on capillarization of the hepatic sinusoids in alcoholic liver disease
    • Urashima S, Tsutsumi M, Nakase K, Wang J-S, Takada A. Studies on capillarization of the hepatic sinusoids in alcoholic liver disease. Alcohol Alcohol 1993;28:77-84.
    • (1993) Alcohol Alcohol , vol.28 , pp. 77-84
    • Urashima, S.1    Tsutsumi, M.2    Nakase, K.3    Wang, J.-S.4    Takada, A.5
  • 41
    • 0026333396 scopus 로고
    • Effect of dietary fat on lto cell activation by chronic ethanol intake: A long-term serial morphometric study on alcohol-fed and control rats
    • Takahashi H, Wang K, Jui L, Nanji AA, Mendenhall CS, French SW. Effect of dietary fat on lto cell activation by chronic ethanol intake: A long-term serial morphometric study on alcohol-fed and control rats. Alcohol Clin Exp Res 1991;15:1060-6.
    • (1991) Alcohol Clin Exp Res , vol.15 , pp. 1060-1066
    • Takahashi, H.1    Wang, K.2    Jui, L.3    Nanji, A.A.4    Mendenhall, C.S.5    French, S.W.6
  • 44
    • 12944258529 scopus 로고
    • Ito cell activation induced by chronic ethanol feeding in the presence of different dietary fats
    • French SW, Takahashi H, Wong K, Mendenhall C. Ito cell activation induced by chronic ethanol feeding in the presence of different dietary fats. Alcohol Alcohol 1991;26(Suppl):357-61.
    • (1991) Alcohol Alcohol , vol.26 , Issue.SUPPL. , pp. 357-361
    • French, S.W.1    Takahashi, H.2    Wong, K.3    Mendenhall, C.4
  • 46
    • 0027209329 scopus 로고
    • Hepatic fibrosis-current concepts of pathogenesis and therapy
    • Hogemann B, Domschke W. Hepatic fibrosis-current concepts of pathogenesis and therapy. Gastroenterol Jpn 1993;28:570-9.
    • (1993) Gastroenterol Jpn , vol.28 , pp. 570-579
    • Hogemann, B.1    Domschke, W.2
  • 47
    • 0030934411 scopus 로고    scopus 로고
    • Tissue inhibition of metalloproteinase-1 and 2 RNA expression in rat and human liver fibrosis
    • Herbst H, Wege T, Milani S, et al. Tissue inhibition of metalloproteinase-1 and 2 RNA expression in rat and human liver fibrosis. Am J Pathol 1997;150:1647-59.
    • (1997) Am J Pathol , vol.150 , pp. 1647-1659
    • Herbst, H.1    Wege, T.2    Milani, S.3
  • 48
    • 0029939342 scopus 로고    scopus 로고
    • Elevated plasma levels of hyaluronic acid indicate endothelial dysfunction in the initial stages of alcoholic liver disease in the rat
    • Nanji AA, Tahan SR, Khwaja S, Yacoub LK, Sadrzadeh SMH. Elevated plasma levels of hyaluronic acid indicate endothelial dysfunction in the initial stages of alcoholic liver disease in the rat. J Hepatol 1996;24:368-74.
    • (1996) J Hepatol , vol.24 , pp. 368-374
    • Nanji, A.A.1    Tahan, S.R.2    Khwaja, S.3    Yacoub, L.K.4    Sadrzadeh, S.M.H.5
  • 49
    • 12944260388 scopus 로고    scopus 로고
    • Expression of the hyaluronate receptor CD44 by liver stellate cells: Splice isoforms in wound repair and role in cell migration
    • Abst
    • Bissell DM, Wang FS, Timmons C. Expression of the hyaluronate receptor CD44 by liver stellate cells: Splice isoforms in wound repair and role in cell migration. Mol Biol Cell 1997;8:396. (Abst)
    • (1997) Mol Biol Cell , vol.8 , pp. 396
    • Bissell, D.M.1    Wang, F.S.2    Timmons, C.3
  • 50
    • 0028892827 scopus 로고
    • Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat
    • Bauer M, Paquette NC, Zhang JX, et al. Chronic ethanol consumption increases hepatic sinusoidal contractile response to endothelin-1 in the rat. Hepatology 1995;22:1565-76.
    • (1995) Hepatology , vol.22 , pp. 1565-1576
    • Bauer, M.1    Paquette, N.C.2    Zhang, J.X.3
  • 51
    • 0021170722 scopus 로고
    • Centrilobular liver necrosis induced by hypoxia in chronic ethanol-fed rats
    • French SW, Benson NC, Sun PS. Centrilobular liver necrosis induced by hypoxia in chronic ethanol-fed rats. Hepatology 1984;4:912-7.
    • (1984) Hepatology , vol.4 , pp. 912-917
    • French, S.W.1    Benson, N.C.2    Sun, P.S.3
  • 52
    • 0027413031 scopus 로고
    • The nature of bile duct changes in alcoholic liver disease
    • Ray MB, Mendenhall CL, French SW, Gartside PS. The nature of bile duct changes in alcoholic liver disease. Liver 1993;13:36-45.
    • (1993) Liver , vol.13 , pp. 36-45
    • Ray, M.B.1    Mendenhall, C.L.2    French, S.W.3    Gartside, P.S.4
  • 53
    • 0029819142 scopus 로고    scopus 로고
    • Bile ductule formation in fetal neonatal and infant livers compared with extrahepatic biliary atresia
    • Cocjin J, Rosenthal P, Bulson V, et al. Bile ductule formation in fetal neonatal and infant livers compared with extrahepatic biliary atresia. Hepatology 1996;24:568-74.
    • (1996) Hepatology , vol.24 , pp. 568-574
    • Cocjin, J.1    Rosenthal, P.2    Bulson, V.3
  • 54
    • 0029819783 scopus 로고    scopus 로고
    • Hepatic stem cells in liver regeneration
    • Thorgiersson SS. Hepatic stem cells in liver regeneration. FASEB J 1996;10:1249-56.
    • (1996) FASEB J , vol.10 , pp. 1249-1256
    • Thorgiersson, S.S.1
  • 55
    • 0028276073 scopus 로고
    • Expression of stem cell factor and its receptor c-kit during liver regeneration from putative stem cells in adult rat
    • Fuji K, Evarts RP, Hu Z, Marsden ER, Thorgeirsson SC. Expression of stem cell factor and its receptor c-kit during liver regeneration from putative stem cells in adult rat. Lab Invest 1994;70:511-6.
    • (1994) Lab Invest , vol.70 , pp. 511-516
    • Fuji, K.1    Evarts, R.P.2    Hu, Z.3    Marsden, E.R.4    Thorgeirsson, S.C.5
  • 56
    • 0031916189 scopus 로고    scopus 로고
    • Cellular localization of endothelin-1 and increased production in liver injury in the rat: Potential for autocrine and paracrine effects on stellate cells
    • Rockey DC, Fovassier L, Chung JJ, et al. Cellular localization of endothelin-1 and increased production in liver injury in the rat: Potential for autocrine and paracrine effects on stellate cells. Hepatology 1998;27:472-80.
    • (1998) Hepatology , vol.27 , pp. 472-480
    • Rockey, D.C.1    Fovassier, L.2    Chung, J.J.3
  • 57
    • 0030993653 scopus 로고    scopus 로고
    • Expression of α-fetoprotein and stem cell factor/c-kit system in bile duct ligated young rats
    • Omori M, Evarts RP, Omori N, Hu Z, Marsden ER, Thorgierson SS. Expression of α-fetoprotein and stem cell factor/c-kit system in bile duct ligated young rats. Hepatology 1997;25:1115-22.
    • (1997) Hepatology , vol.25 , pp. 1115-1122
    • Omori, M.1    Evarts, R.P.2    Omori, N.3    Hu, Z.4    Marsden, E.R.5    Thorgierson, S.S.6
  • 58
    • 0027932181 scopus 로고
    • Human biliary epithelial cells secretic and respond to cytokines, and hepatocytic growth factors in vitro: Interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro
    • Matsumoto K, Fuji H, Michalopoulus C, Fung JJ, Demetris AJ. Human biliary epithelial cells secretic and respond to cytokines, and hepatocytic growth factors in vitro: Interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro. Hepatology 1994;20:376-82.
    • (1994) Hepatology , vol.20 , pp. 376-382
    • Matsumoto, K.1    Fuji, H.2    Michalopoulus, C.3    Fung, J.J.4    Demetris, A.J.5
  • 59
    • 0031961925 scopus 로고    scopus 로고
    • Mallory body formation by ethanol feeding in drug-primed mice
    • Zhang-Gouillon ZQ, Yuan QX, Hu B, et al. Mallory body formation by ethanol feeding in drug-primed mice. Hepatology 1998;27:116-22.
    • (1998) Hepatology , vol.27 , pp. 116-122
    • Zhang-Gouillon, Z.Q.1    Yuan, Q.X.2    Hu, B.3
  • 60
    • 0031744134 scopus 로고    scopus 로고
    • Mechanisms of Mallory body formation induced by okadaic acid in drug primed mice
    • Yuan QX, Nagao Y, Gaal K, Hu B, French SW. Mechanisms of Mallory body formation induced by okadaic acid in drug primed mice. Exp Mol Pathol 1998;65:87-103.
    • (1998) Exp Mol Pathol , vol.65 , pp. 87-103
    • Yuan, Q.X.1    Nagao, Y.2    Gaal, K.3    Hu, B.4    French, S.W.5
  • 61
    • 0027815262 scopus 로고
    • Molecular structural changes in Mallory body protein in human and mouse livers. An infrared spectroscopy study
    • Kachi K, Wong PTT, French SW. Molecular structural changes in Mallory body protein in human and mouse livers. An infrared spectroscopy study. Exp Mol Pathol 1993;59:187-210.
    • (1993) Exp Mol Pathol , vol.59 , pp. 187-210
    • Kachi, K.1    Wong, P.T.T.2    French, S.W.3
  • 62
    • 0024239290 scopus 로고
    • Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes
    • Ohta M, Marceau N, Perry C, et al. Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes. Lab Invest 1988;59:848-56.
    • (1988) Lab Invest , vol.59 , pp. 848-856
    • Ohta, M.1    Marceau, N.2    Perry, C.3
  • 63
    • 0025039794 scopus 로고
    • Ethanol-induced phosphorylation of cytokeratin in cultured hepatocytes
    • Kawahara H, Cadrin M, French SW. Ethanol-induced phosphorylation of cytokeratin in cultured hepatocytes. Life Sci 1990;47;859-63.
    • (1990) Life Sci , vol.47 , pp. 859-863
    • Kawahara, H.1    Cadrin, M.2    French, S.W.3
  • 64
    • 0005025765 scopus 로고
    • Cytoskeleton: Intermediate filaments
    • Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter DA, Shafritz DA, eds. New York: Raven Press
    • French SW. Cytoskeleton: Intermediate filaments. In: Arias IM, Boyer JL, Fausto N, Jakoby WB, Schachter DA, Shafritz DA, eds. the Liver: Biology and Pathobiology, 3rd edn. New York: Raven Press, 1994:33-44.
    • (1994) The Liver: Biology and Pathobiology, 3rd Edn. , pp. 33-44
    • French, S.W.1
  • 65
    • 0028978217 scopus 로고
    • Activation of NF kappa b by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites
    • Sun SC, Magqirwar SR, Harhad E. Activation of NF kappa b by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites. J Biol Chem 1995;270:18347-51.
    • (1995) J Biol Chem , vol.270 , pp. 18347-18351
    • Sun, S.C.1    Magqirwar, S.R.2    Harhad, E.3
  • 66
    • 12944258887 scopus 로고    scopus 로고
    • Changes in the phosphorylation of the hepatic keratins 8/18 in human alcoholic hepatitis and in experimentally intoxicated mouse liver
    • Abst
    • Stumptner C, Omary MB, Denk H, Zatloukal K. Changes in the phosphorylation of the hepatic keratins 8/18 in human alcoholic hepatitis and in experimentally intoxicated mouse liver. Hepatology 1998;28:512. (Abst)
    • (1998) Hepatology , vol.28 , pp. 512
    • Stumptner, C.1    Omary, M.B.2    Denk, H.3    Zatloukal, K.4
  • 67
    • 12944284385 scopus 로고    scopus 로고
    • Role of protein kinases and phosphatases in the pathogenesis of liver disease and related animal models
    • Abst
    • Guertl B, Stumptner C, Zatloukal K, Denk H. Role of protein kinases and phosphatases in the pathogenesis of liver disease and related animal models. Hepatology 1998;28:638. (Abst)
    • (1998) Hepatology , vol.28 , pp. 638
    • Guertl, B.1    Stumptner, C.2    Zatloukal, K.3    Denk, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.