Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma

Anticancer Research

Volumn 17, Issue 3 C, 1997, Pages 2241-2247

  Hao, Xingpei ^a   Palazzo, Juan P ^b   Ilyas, Mohammad ^a,c   Tomlinson, Ian ^d   Talbot, Ian C ^a  

^a ST MARK S HOSPITAL   (United Kingdom)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Adenoma carcinoma sequence; Adhesion molecules; Cadherin catenin complex; Colorectum

Indexed keywords

ACTIN; ALPHA CATENIN; BETA CATENIN; CADHERIN; CATENIN; UVOMORULIN;

ARTICLE; COLON ADENOMA; COLORECTAL CARCINOMA; COLORECTAL TUMOR; CYTOSKELETON; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL; RECTUM ADENOMA;

ADENOMA; ALPHA CATENIN; BETA CATENIN; CADHERINS; CARCINOMA; COLORECTAL NEOPLASMS; CYTOSKELETAL PROTEINS; DESMOPLAKINS; DISEASE PROGRESSION; GAMMA CATENIN; GENE EXPRESSION; HUMANS; INTESTINAL MUCOSA; NEOPLASM INVASIVENESS; RETROSPECTIVE STUDIES; TRANS-ACTIVATORS;

EID: 0030800317     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Takeichi M: Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251: 1451-1455, 1991.
2. Kemler R: From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 9: 317-321, 1993.
3. Nagafuchi A and Takeichi M: Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO 7: 3679-3684, 1988.
4. Ozawa M, Baribault H and Kemler R: The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO 8: 1711-1717, 1989.
5. Ozawa M, Ringwald M and Kemler R: Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc Natl Acad Sci USA 87: 4246-4250, 1990.
6. Kintner C: Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell 69: 225-236, 1992.
7. Nagafuchi A, Takeichi M and Tsukita S: The 102 Kd cadherin-associated protein: similarity to vinculin and posttranscriptional regulation of expression. Cell 65: 849-857, 1991.
8. Herrenknecht K, Ozawa M, Eckerskorn C, Lottspeich F, Lenter M and Kemler R: The uvomorulin-anchorage protein alpha catenin is a vinculin homologue. Proc Natl Acad Sci USA. 88: 9156-9160, 1991.
9. Hirano S, Kimoto N, Shimoyama Y, Hirohashi S and Takeichi M: Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organisation. Cell 70: 293-301, 1992.
10. McCrea PD, Turck CW and Gumbiner BM: A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science 254: 1359-1361, 1991.
11. Peifer M, McCrea PD, Green KJ, Wieschaus E and Gumbiner BM: The vertebrate adhesive junction proteins β-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties. J Cell Biol 118: 681-691, 1992.
12. Butz S, Stappert J, Weissig H and Kemler R: Plakoglobin and beta-catenin: distinct but closely related. Science, 257: 1142-1144, 1992.
13. Cowin P, Kapprell HP, Franke WW, Tamkun J and Hynes RO: Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell 46: 1063-1073, 1986.
14. Franke WW, Goldschmidt MD, Zimbelmann R, Mueller HM, Schiller DL and Cowin P: Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein. Proc Natl Acad Sci USA 86: 4027-4031, 1989.
15. Hinck L, Nelson WJ and Papkoff J: Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilising β-catenin binding to the cell adhesion protein cadherin. J Cell Biol 124: 729-741, 1994.
16. Hinck L, Nathke I, Papkoff J and Nelson WJ: Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J Cell Biol 125: 1327-1340, 1994.
17. Pignatelli M, Liu D, Nasim MM, Stamp GWH, Hirano S and Takeichi M: Morphoregulatory activities of E-cadherin and beta-1 integrins in colorectal tumour cells. Br J Cancer 66: 629-634, 1992.
18. Liu D, Nigam AK, Lalani E-N, Stamp GWH and Pignatelli M: Transfection of E-cadherin into a human colon carcinoma cell line induces differentiation and inhibits growth in vitro. Gut 34: S27, 1993.
19. Vermeulen SJ, Bruyneel EA, Bracke ME, De Bruyne GK, Vennekens KM, Vleminckx KL, Berx GJ, van Roy FM and Marcel MM: Transition from the noninvasive to the invasive phenotype and loss of α-catenin in human colon cancer cells. Cancer Res 55: 4722-4728, 1995.
20. Oyama T, Kanai Y, Ochiai A, Akimoto S, Oda T, Yanagihara K, Nagafuchi A, Tsukita S, Shibamoto S, Ito F, Takeichi M, Matsuda H and Hirohashi S: A trunctcd β-catenin disrupts the interaction between E-cadherin and α-catenin: a cause of loss intercellular adhesiveness in human cancer cell lines. Cancer Res 54: 6282-6287, 1994.
21. Kawanishi J, Kato J, Sasaki K, Fujii S, Watanabe N and Niitsu Y: Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the β-catenin gene in a human cancer cell line, HSC-39. Mol Cell Biol 15: 1175-1181, 1995.
22. Van Der Wurff AAM, Kate JT, Van Der Linden PM, Dinjens WNM, Arends JW and Bosnian FT: L-CAM expression in normal premalignant, and malignant colon mucosa. J Pathol 168: 287-291, 1992.
23. Van Aken J, Cuvelier CA, De Wever N, Reels J, Gao J and Mareel MM: Immunohistochemical analysis of E-cadherin expression in human colorectal tumours. Pathol Res Pract 189: 975-978, 1993.
24. Dorudi S, Sheffield JP, Poulsom R, Northover JMA and Hart IR: E-cadherin expression in colorectal cancer: An immunocytochemical and in situ hybridisation study. Am J Pathol 142: 981-986, 1993.
25. Kinsella AR, Green B, Lepts GC, Hill CL, Bowie G and Taylor BA: The rule of the cell-cell adhesion molecule E-cadherin in large bowel tumour cell invasion and metastasis. Br J Cancer 67: 904-909, 1993.
26. Nigam AK, Savage FJ, Boulos PB, Stamp GWH, Liu D and Pignatelli M: Loss of cell-cell and cell-matrix adhesion molecules in colorectal cancer. Br J Cancer 68: 507-514, 1993.
27. Van Der Wurff AAM, Arends JW, Van Der Linden EPM, Kate JT and Bosman FT: L-CAM expression in lymph node and liver metastases of colorectal carcinomas. J Pathol 172: 177-182, 1994.
28. Gagliardi G, Kandemir O, Liu D, Guida M, Benvestito S, Ruers TGM, Benjamin IS, Northover JMA, Stamp GWH, Talbot IC and Pignatelli M: Changes of E-cadherin immunoreactivity in the adenoma-carcinoma sequence of the large bowel. Virchows Archiv 426: 149-154, 1995.
29. Sinicrope F, Ruan SB, Cleary KR, Stephens LC, Lee JJ and Levin B: Bcl-2 and p53 oncoprotein expression during colorectal tumourigenesis. Cancer Res 55: 237-241, 1995.
30. Yasui W, Kuniyasu H, Akama Y, Kitahara K, Nagafuchi A, Ishihara S, Tsukita S and Tahara E: Expression of E-cadherin, α- and β-catenins in human gastric carcinomas: correlation with histology and tumour progression. Oncol Reports 2: 111-117, 1995.
31. Kadowaki T, Shiozaki H, Inoue M, Tamura S, Oka H, Doki Y, Iihara K, Matsui S, Iwazawa T, Nagafuchi A, Tsukita S and Mori T: E-cadherin and α-catenin expression in human esophageal cancer. Cancer Res 55: 291-296, 1994.
32. Hashizume R, Koizumi H, Ihara A, Ohta T and Uchikoshi T: Expression of β-catenin in normal breast tissue and breast carcinoma: a comparative study with epithelial eadherin and α-catenin. Histopathology 29: 139-146, 1996.
33. cas in bladder tumours. Cancer Res 56: 4154-4158, 1996.
34. Oka H, Shiozaki H, Kobayashi J, Inoue M, Tahara H, Kobayashi T, Takatsuka Y, Matsuyoshi N, Hirano S, Takeichi M and Mori T: Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 53:1696-1701, 1993.
35. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, Lochner D and Birchmeier E: E-Cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 113: 173-185, 1991.
36. Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B and Kinzler KW: APC mutations occur early during colorectal tumourigenesis. Nature 359: 235-237, 1992.
37. Behens J, Vakaet L, Friis R, Winterhager E, Van Roy F, Marcel MM and Birchmeier W: Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/β-catenin complex in cells transformed with a temperature-sensitive v-src gene. J Cell Biol 120: 757-766, 1993.
38. Shibamoto S, Hayakawa M, Takeuchi K, Hori T, Oku N, Miyazawa K, Kitamura N, Takeichi M and Ito F: Tyrosine phosphorylation of β-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhesion Commun 1: 295-305, 1994.