Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae

Chemistry and Biology

Volumn 5, Issue 11, 1998, Pages 661-667

  Xue, Yongquan ^a   Wilson, Daniel ^a   Zhao, Lishan ^b   Liu, Hung Wen ^b   Sherman, David H ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b NONE   (United States)

Author keywords

Cytochrome P450; Macrolide antibiotics; Narbomycin; Polyketide synthase; YC 17

Indexed keywords

CARBON; CULTURE MEDIUM; CULTURE TECHNIQUE; CYTOCHROME P450; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE CLUSTER; HIS TAGGED PROTEIN; HYDROXYLATION; MACROLACTONE; METHYMYCIN; MICROBE METABOLISM; NARBOMYCIN; NEOMETHYMYCIN; PIKROMYCIN; SECONDARY METABOLITE;

STREPTOMYCES VENEZUELAE;

EID: 0032213230     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(98)90293-9     Document Type: Article

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