Oxidized-LDL and atherosclerosis role of LOX-1

Annals of the New York Academy of Sciences

Volumn 902, Issue , 2000, Pages 95-102

  Kita, Toru ^a   Kume, Noriaki ^a   Yokode, Masayuki ^a   Ishii, Kenji ^a   Arai, Hidenori ^a   Horiuchi, Hisanori ^a   Moriwaki, Hideaki ^a   Minami, Manabu ^a   Kataoka, Hiroharu ^a   Wakatsuki, Yoshio ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; LYSOPHOSPHATIDYLCHOLINE; OXIDIZED LOW DENSITY LIPOPROTEIN;

ARTERY INTIMA; ATHEROGENESIS; ATHEROSCLEROSIS; CONFERENCE PAPER; DIABETES MELLITUS; HUMAN; HYPERLIPIDEMIA; MACROPHAGE; MONOCYTE; NONHUMAN; RECEPTOR BINDING; T LYMPHOCYTE;

EID: 0034086135     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06304.x     Document Type: Conference Paper

References (45)

1. 1. BROWN, M.S. & J.L. GOLDSTEIN. 1986. A receptor-mediated pathway for cholesterol homeostasis. Science 232: 34-47.
2. 2. RUSSELL, R. 1993. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 362: 801-809.
3. 3. STEINBERG, D. 1997. Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272: 20963-20968.
4. 4. KEIDAR, S., M. KAPLAN, C. SHAPIRA, J.G. BROOK & M. AVIRAM. 1994. Low density lipoprotein isolated from patients with essential hypertension exhibits increased propensity for oxidation and enhanced uptake by macrophages: A possible role for angiotensin II. Atherosclerosis 107: 71-84.
5. 5. ALDERMAN, M.H., S. MADHAVAN, W.L. OOI, H. COHEN, J.E. SEALEY & J.H. LARAGH. 1991. Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension. N. Engl. J. Med. 324: 1098-1104.
6. 6. CHOBANIAN, A.V., C.C. HAUDENSCHILD, C. NICKERSON & S. HOPE. 1992. Trandolapril inhibits atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. Hypertension 20: 473-477.
7. 7. FURUKAWA, Y, A. MATSUMORI, T. HIROZANE & S. SASAYAMA. 1996. Angiotensin II receptor antagonist TVC-116 reduces graft coronary artery disease and preserves graft status in a murine model: a comparative study with captopril. Circulation 93: 333-339.
8. 8. DZAU, V.J., G.H. GIBBONS, H.P. COOKE & N. OMOIGUL. 1993. Vascular biology and medicine in the 1990s: scope, concepts, potentials, and perspectives. Circulation 87: 705-719.
9. 9. ALBERG, G. & P. FERRER. 1990. Effects of captopril on atherosclerosis in cynomolgus monkeys. J. Cardiovasc. Pharmacol. 15(5): S65-S72.
10. 10. Ross, R. 1999. Atherosclerosis - an inflammatory disease. N. Engl. J. Med. 340(2): 115-126.
11. 11. KITA, T., Y. NAGANO, M. YOKODE, K. ISHII, N. KUME, A. OOSIMA et al. 1987. Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc. Natl. Acad. Sci. USA 84: 5928-5931.
12. 12. YLA-HERTTUALA, S. W. PALINSKI, M.E. ROSENFELD, S. PARTHASARATHY, T.E. CAREW, S. BUTLER et al. 1989. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J. Clin. Invest. 84: 1086-1095.
13. 13. QUINN, M.T., S. PARTHASARATHY, L.G. FONG & D. STEINBERG. 1987. Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc. Natl. Acad. Sci. USA 84: 2995-2998.
14. 14. HESSLER, J.R., D.W. MOREL, L.J. LEWIS & G.M. CHISOLM. 1983. Lipoprotein oxidation and lipoprotein-induced cytotoxicity. Arteriosclerosis 3: 215-222.
15. 15. YUI, S., T. SASAKI, A. MIYAZAKI, S. HORIUCHI & M. YAMAZAKI. 1993. Induction of murine macrophage growth by modified LDLs. Arterioscler. Thromb. 13: 331-337.
16. 16. KRIEGER, M. 1997. The other side of scavenger receptors: pattern recognition for host defense. Curr. Opinion Lipidol. 8: 275-280.
17. 17. YLA-HERTTUALA, S. 1998. Is oxidized low-density lipoprotein present in vivo? Curr. Opin. Lipidol. 9: 337-344.
18. 18. SAKAI, M., M. SHINCHIRI, H. HAKAMATA & S. HORIUCHI. 1998. Endocytosed lysophosphatidylcholine, through the scavenger receptor, plays an essential role in oxidized low-density lipoprotein-induced macrophage proliferation. Trends Cardiovasc. Med. 8: 119-124.
19. 19. NAGY, L., P. TONTONOZ, J.G.A. ALVAREZ, H. CHEN & R.M. EVANS. 1998. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ. Cell 93: 229-240.
20. 20. TONTONOZ, P., L. NAGY, J.G.A. ALVAREZ, V.A. THOMAZY & R.M. EVANS. 1998. PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93: 241-252.
21. 21. KUGIYAMA, K., S.A. KEMS, J.D. MORRISETT, R. ROBERTS & P.D. HENRY. 1990. Impairment of endothelium-dependent arterial relaxation isolecithin in modified low-density lipoproteins. Nature 344: 160-162.
22. 22. KUME, N., M.I. CYBULSKY, JR. & M.A. GIMBRONE. 1992. Lysophosphatidyl-choline, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J. Clin. Invest. 90: 1138-1144.
23. 23. KUME, N. & M.A. GIMBRONE, JR. 1994. Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells. J. Clin. Invest. 93: 907-911.
24. 24. OCHI, H., N. KUME, E. NISHI, H. MORIWAKI, M. MASUDA, K. FUJIKAWA & T. KITA. 1998. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 induced by lysophosphatidyl-choline in cultured endothelial cells. Biochem. Biophys. Res. Commun. 243: 862-868.
25. 25. KUME, N., H. ARAI, C. KAWAI & T. KITA. 1991. Receptors for modified low-density lipoproteins on human endothelial cells: different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein. Biochim. Biophys. Acta 1091: 63-67.
26. 26. SAWAMURA, T., N. KUME, T. AOYAMA, H. MORIWAK, H. HOSHIKAWA, Y. ARIBA, T. TANAKA, S. MIWA, Y. KATSURA, T. KITA & T. MASAKI. 1997. An endothelial receptor for oxidized low-density lipoprotein. Nature 386: 73-77.
27. 27. AOYAMA, T., T. SAWAMURA, Y. FURUTANI, R. MATSUOKA, M. YOSHIDA, H. FUJIWARA & T. MASAKI. 1999. Structure and chromosomal assignment of the human lectin-like oxidized low-density lipoprotein receptor-I (Lox-1) gene. Biochem. J. 339: 177-184.
28. 28. KUME, N., T. MURASE, H. MORIWAKI, T. AOYAMA, T. SAWAMURA, T. MASAKI & T. KITA. 1998. Inducible expression of lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ. Res. 83: 322-327.
29. 29. MURASE, T., N. KUME, R. KORENAGA, J. ANDO, T. SAWAMURA, T. MASAKI & T. KITA. 1998. Fluid shear stress transcriptionally induces lectin-like oxidized low density lipoprotein receptor-1 in vascular endothelial cells. Circ. Res. 83: 328-333.
30. 30. KATAOKA, H., N. KUME, S. MIYAMOTO, M. MINAMI, H. MORIWAKI, T. MURASE, T. SAWANMURA, T. MASAKI, N. HASHIMOTO & T. KITA. 1999. Expression of lectin like oxidized LDL receptor-I human atherosclerosis lesions. Circulation 99: 3110-3117.
31. 31. NAGASE, M., S. HIROSE, T. SAWAMURA, T. MASAKI & T. FUJITA. 1997. Enhanced expression of endothelial oxidized low-density lipoprotein receptor (Lox-1) in hypertensive rats. Biochem. Biophys. Res. Commun. 237: 496-498.
32. 32. NAGASE, M., S. HIROSE & T. FUJITA. 1998. Unique repetitive sequence and unexpected regulation of expression of rat endothelial receptor for oxidized low-density lipoprotein. Biochem. J. 330: 1417-1422.
33. 33. NAOASE, M., J. ABE, K. TAKAHASHI, J. ANDO, S. HIROSE & T. FUJITA. 1998. Genomic organization and regulation of expression of the lectin-like oxidized low-density lipoprotein receptor (Lox-1) gene. J. Biol. Chem. 278: 33702-33707.
34. 34. MORIWAKI, H., N. KUME, T. SAWAMURA, T. AOYAMA, H. HOSHIIKAWA, H. OCHI, H. NISHI, E. MASAKI & T. KITA. 1998. Ligand specificity of Lox-1, a novel endothelial receptor for oxidized low density lipoprotein. Arterioscler. Thromb. Vasc. Biol. 18: 1541-1547.
35. 35. YOSHIDA, H., N. KONDRATENKO, S. GREEN, D. STEINBERG & O. QUEHENBERGER. 1998. Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor. Biochem. J. 334: 9-13
36. 36. MORIWAKI, H., N. KUME, H. KATAOKA, T. MURASE, T. SAWAMURA, T. MASAKI & T. KITA. 1998. Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages-upregulated expression by TNF-α. FEBS Lett. 440: 29-32.
37. 37. CAMBIEN, F., O. POIRER, L. LECERF, A. EVENS, J.P. CAMBOU, G. ARVOILER, G. LUC, J.M. BARD, L. BARA & S. RICHARD. 1992. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359: 641-644.
38. 38. PITT, B. 1994. Angiotensin-converting enzyme inhibitors in patients with coronary atherosclerosis. Am. Heart J. 128: 1328-1332.
39. 39. GRIENDLING, K.K., C.A. MINIERI, J.D. OLLERENSHAW & R.W. ALEXANDER. 1994. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 74: 1141-1148.
40. 40. RAJAGOPALAN, S., S. KURZ, T. MUNZEL, M. TARPEY, B.A. GREEMAN, K.K. GRIENDLING & D.G. HARRISON. 1996. Angiotensin II mediated hypertension in the rat increases vascular Superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J. Clin. Invest. 97: 1916-1923.
41. 41. CAPERS, Q.I., R.W. ALEXANDER, P. LOU, H. DE LEON, J.N. WILCOX, N. ISHIZAKA, A.B. HOWARD & V.V.R. TAYLOR. 1997. Monocyte chemoattractant protein-1 expression in aortic tissues of hypertensive rats. Hypertension 30: 1397-1402.
42. 42. CHEN, X.-L., P.E. TUMMALA, M.T, OLBRYCH, R.W. ALEXANDER & R.M. MEDFORD. 1998. Angiotensin II induces monocyte chemoattractant protein-1 gene expression in rat vascular smooth muscle cells. Circ. Res. 83: 952-959.
43. 43. LI, D.Y., Y.C. ZHANG, N.H. PHILLIPS, T. SAWAMURA & J.L. MEHTA. 1999. Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activation. Circ. Res. 84: 1043-1049.
44. 44. RUECKSCHLOSS, U., H. MORAWLETZ, H. HACK, K. HAKIM, H.R. ZERKOWSKI & J. HOLTZ. 1997. The endothelial receptor for oxidized low-density lipoprotein is down-regulated in arteries of patients under therapy with angiotensin converting enzyme inhibitors. Circulation 96(Suppl I): 1-21 (Abstract 115).
45. 45. KITA, T. 1999. Lox-1, a possible clue to the missing link between hypertension and atherogenesis. Circ. Res. 84: 1113-1115.