Thresholds for Genotoxic Carcinogens: DNA Repair: Kinetics and Thresholds

Toxicologic Pathology

Volumn 28, Issue 3, 2000, Pages 375-381

  O'connor, Peter J ^a   Manning, Francis C R ^b,c   Gordon, Anthony T ^b   Billett, Michael A ^b   Cooper, Donald P ^a,d   Elder, Rhoderick H ^a   Margison, Geoffrey P ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^d MICROMASS UK LTD   (United Kingdom)

Author keywords

chromatin DNA; DNA repair mechanisms; DNA repair deficient DNA sequences; O6 alkylguanine DNA alkyltransferase; O6 methylguanine; target cells

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; ALKYLATING AGENT;

CARCINOGENESIS; CELL PROTECTION; DNA ALKYLATION; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; KINETICS; MAXIMUM ALLOWABLE CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; TARGET CELL;

ALKYLATING AGENTS; ANIMALS; CHROMATIN; DNA; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE; HUMANS; TIME FACTORS;

MAMMALIA;

EID: 0034084245     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262330002800304     Document Type: Article

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