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Volumn 113, Issue 5, 2000, Pages 349-361

Disruption of epithelial tight junctions is prevented by cyclic nucleotide-dependent protein kinase inhibitors

Author keywords

Calcium switch; Epithelial cells; Protein kinase A; Tight junction

Indexed keywords

ACTIN; CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC NUCLEOTIDE DEPENDENT PROTEIN KINASE; N (2 GUANIDINOETHYL) 5 ISOQUINOLINESULFONAMIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OCCLUDIN; PROTEIN KINASE INHIBITOR;

EID: 0034081339     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180000143     Document Type: Article
Times cited : (46)

References (66)
  • 1
    • 33750870793 scopus 로고    scopus 로고
    • Micro-vascular permeability and number of tight junctions are modulated by cAMP
    • Adamson RH, Liu B, Fry GN, Rubin LL, Curry FE (1998) Micro-vascular permeability and number of tight junctions are modulated by cAMP. Am J Physiol 43:H1885-H1894
    • (1998) Am J Physiol , vol.43
    • Adamson, R.H.1    Liu, B.2    Fry, G.N.3    Rubin, L.L.4    Curry, F.E.5
  • 5
    • 0029799520 scopus 로고    scopus 로고
    • Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
    • Balda MS, Whitney JA, Flores C, Gonzales S, Cereijido M, Matter K (1996) Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J Cell Biol 134:1031-1049
    • (1996) J Cell Biol , vol.134 , pp. 1031-1049
    • Balda, M.S.1    Whitney, J.A.2    Flores, C.3    Gonzales, S.4    Cereijido, M.5    Matter, K.6
  • 6
    • 0032769698 scopus 로고    scopus 로고
    • A dominant mutant of occludin disrupts tight junction structure and function
    • Bamforth SD, Kniesel U, Wolburg H, Engelhardt B, Risau W (1999) A dominant mutant of occludin disrupts tight junction structure and function. J Cell Sci 112:1879-1888
    • (1999) J Cell Sci , vol.112 , pp. 1879-1888
    • Bamforth, S.D.1    Kniesel, U.2    Wolburg, H.3    Engelhardt, B.4    Risau, W.5
  • 7
    • 0001964701 scopus 로고
    • Evolution of ideas on the tight junction
    • Cereijido M (ed). CRC Press, Boca Raton
    • Cereijido M (1991) Evolution of ideas on the tight junction. In: Cereijido M (ed) Tight junctions. CRC Press, Boca Raton, pp 1-13
    • (1991) Tight Junctions , pp. 1-13
    • Cereijido, M.1
  • 10
    • 0026505270 scopus 로고
    • Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells
    • Citi S (1992) Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells. J Cell Biol 117:169-178
    • (1992) J Cell Biol , vol.117 , pp. 169-178
    • Citi, S.1
  • 12
    • 0028273266 scopus 로고
    • Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7
    • Citi S, Volberg T, Bershadsky AD, Denisenko N, Ceiger B (1994) Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7. J Cell Sci 107: 683-692
    • (1994) J Cell Sci , vol.107 , pp. 683-692
    • Citi, S.1    Volberg, T.2    Bershadsky, A.D.3    Denisenko, N.4    Ceiger, B.5
  • 13
    • 0031809132 scopus 로고    scopus 로고
    • Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia
    • Collares-Buzato CB, Jepson MA, Simmons NL, Hirst BH (1998) Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia. Eur J Cell Biol 76:85-92
    • (1998) Eur J Cell Biol , vol.76 , pp. 85-92
    • Collares-Buzato, C.B.1    Jepson, M.A.2    Simmons, N.L.3    Hirst, B.H.4
  • 15
    • 0028285028 scopus 로고
    • Different effects of protein kinase inhibitors on the localization of junctional proteins at cell-cell contact sites
    • Denisenko N, Burighel P, Citi S (1994) Different effects of protein kinase inhibitors on the localization of junctional proteins at cell-cell contact sites. J Cell Sci 107:969-981
    • (1994) J Cell Sci , vol.107 , pp. 969-981
    • Denisenko, N.1    Burighel, P.2    Citi, S.3
  • 16
    • 0029862538 scopus 로고    scopus 로고
    • Involvement of a heterotrimeric G protein subunit in tight junction biogenesis
    • Denker BM, Saha C, Khawaja S, Nigam SK (1996) Involvement of a heterotrimeric G protein subunit in tight junction biogenesis. J Biol Chem 271:25750-25753
    • (1996) J Biol Chem , vol.271 , pp. 25750-25753
    • Denker, B.M.1    Saha, C.2    Khawaja, S.3    Nigam, S.K.4
  • 17
    • 0032491391 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    • Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM (1998) The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 273:29745-29753
    • (1998) J Biol Chem , vol.273 , pp. 29745-29753
    • Fanning, A.S.1    Jameson, B.J.2    Jesaitis, L.A.3    Anderson, J.M.4
  • 19
    • 0028110309 scopus 로고
    • Direct association between occludin and ZO-1 and its possible involvement in the localization of occludin at tight junctions
    • Furuse M, Itoh M, Hirase T, Nagafuchi F, Yonemura S, Tsukita S (1994) Direct association between occludin and ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol 127:1617-1626
    • (1994) J Cell Biol , vol.127 , pp. 1617-1626
    • Furuse, M.1    Itoh, M.2    Hirase, T.3    Nagafuchi, F.4    Yonemura, S.5    Tsukita, S.6
  • 20
    • 0032547833 scopus 로고    scopus 로고
    • A single gene product claudin-1 or -2 reconstitutes tight junction strands and recruits occludin in fibroblasts
    • Furuse M, Sasaki H, Fujimoto K, Tsukita S (1998) A single gene product claudin-1 or -2 reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 143:391-401
    • (1998) J Cell Biol , vol.143 , pp. 391-401
    • Furuse, M.1    Sasaki, H.2    Fujimoto, K.3    Tsukita, S.4
  • 21
    • 0027194031 scopus 로고
    • Characterization of distinct tethering and intracellular targeting domains in AKAP75 a protein that links cAMP-dependent protein kinase II beta to the cytoskeleton
    • Glantz SB, Li Y, Rubin CS (1993) Characterization of distinct tethering and intracellular targeting domains in AKAP75 a protein that links cAMP-dependent protein kinase II beta to the cytoskeleton. J Biol Chem 268:12796-12804
    • (1993) J Biol Chem , vol.268 , pp. 12796-12804
    • Glantz, S.B.1    Li, Y.2    Rubin, C.S.3
  • 24
    • 0026345292 scopus 로고
    • Identification of 160-kDa polypeptide that binds to the tight junction protein ZO-1
    • Gumbiner B, Lowenkopf T, Apatira D (1991) Identification of 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci USA 88:3460-3464
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3460-3464
    • Gumbiner, B.1    Lowenkopf, T.2    Apatira, D.3
  • 25
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A (1998) Rho GTPases and the actin cytoskeleton. Science 279:509-514
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 26
    • 0032489875 scopus 로고    scopus 로고
    • ZO-3 a novel member of the MAGUK protein family found at the tight junction interacts with ZO-1 and occludin
    • Haskins J, Gu L, Wittchen ES, Hibbard J, Stevenson BR (1998) ZO-3 a novel member of the MAGUK protein family found at the tight junction interacts with ZO-1 and occludin. J Cell Biol 141:199-208
    • (1998) J Cell Biol , vol.141 , pp. 199-208
    • Haskins, J.1    Gu, L.2    Wittchen, E.S.3    Hibbard, J.4    Stevenson, B.R.5
  • 28
    • 0020352825 scopus 로고
    • Interactions between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear
    • Hirokawa N, Tilney LG (1982) Interactions between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear. J Cell Biol 95:249-261
    • (1982) J Cell Biol , vol.95 , pp. 249-261
    • Hirokawa, N.1    Tilney, L.G.2
  • 29
    • 0031974042 scopus 로고    scopus 로고
    • The structure of cell-adhesion molecules
    • Humphries MJ, Newham P (1998) The structure of cell-adhesion molecules. Trends Cell Biol 8:78-83
    • (1998) Trends Cell Biol , vol.8 , pp. 78-83
    • Humphries, M.J.1    Newham, P.2
  • 30
    • 0030983484 scopus 로고    scopus 로고
    • Occludin confers adhesiveness when expressed in fibroblasts
    • Itallie CM van, Anderson JM (1997) Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci 110:1113-1121
    • (1997) J Cell Sci , vol.110 , pp. 1113-1121
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 31
    • 0028287035 scopus 로고
    • Molecular characterization and tissue distribution of ZO-2 a tight junction protein homologous to ZO-1 and the drosophila disc-large tumor suppressor protein
    • Jesaitis LA, Goodenough DA (1994) Molecular characterization and tissue distribution of ZO-2 a tight junction protein homologous to ZO-1 and the drosophila disc-large tumor suppressor protein. J Cell Biol 124:949-961
    • (1994) J Cell Biol , vol.124 , pp. 949-961
    • Jesaitis, L.A.1    Goodenough, D.A.2
  • 32
    • 0032514134 scopus 로고    scopus 로고
    • Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases
    • Jou TS, Schneeberger EE, Nelson WJ (1998) Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol 142:101-115
    • (1998) J Cell Biol , vol.142 , pp. 101-115
    • Jou, T.S.1    Schneeberger, E.E.2    Nelson, W.J.3
  • 34
    • 0030612562 scopus 로고    scopus 로고
    • 2+-sensing receptor (CaR) activates phospholipase C A2 and D in bovine parathyroid and in CaR-transfected human embryonic kidney (HEK293) cells
    • 2+-sensing receptor (CaR) activates phospholipase C A2 and D in bovine parathyroid and in CaR-transfected human embryonic kidney (HEK293) cells. J Bone Miner Res 12:715-725
    • (1997) J Bone Miner Res , vol.12 , pp. 715-725
    • Kifor, O.1    Diaz, R.2    Butters, R.3    Brown, E.M.4
  • 35
    • 0029904265 scopus 로고    scopus 로고
    • A kinase anchor protein 75 targets regulatory (RII) subunits of cAMP-dependent protein kinase II to the cortical actin cytoskeleton in non-neuronal cells
    • Li Y, Ndubuka C, Rubin CS (1996) A kinase anchor protein 75 targets regulatory (RII) subunits of cAMP-dependent protein kinase II to the cortical actin cytoskeleton in non-neuronal cells. J Biol Chem 271:16862-16869
    • (1996) J Biol Chem , vol.271 , pp. 16862-16869
    • Li, Y.1    Ndubuka, C.2    Rubin, C.S.3
  • 36
    • 0028948118 scopus 로고
    • Thyroid hormone regulates stromelysin expression protease secretion and the morphogenic potential of normal polarized mammary epithelial cells
    • Lopez-Barahona M, Fialka I, Gonzalez-Sancho JM, Asuncion M, Gonzalez M, Iglesias T, Bernal J, Beug H, Munoz A (1995) Thyroid hormone regulates stromelysin expression protease secretion and the morphogenic potential of normal polarized mammary epithelial cells. EMBO J 14:1145-1155
    • (1995) EMBO J , vol.14 , pp. 1145-1155
    • Lopez-Barahona, M.1    Fialka, I.2    Gonzalez-Sancho, J.M.3    Asuncion, M.4    Gonzalez, M.5    Iglesias, T.6    Bernal, J.7    Beug, H.8    Munoz, A.9
  • 37
    • 0023176321 scopus 로고
    • Intestinal absorptive cell tight junctions are linked to cytoskeleton
    • Madara JL (1987) Intestinal absorptive cell tight junctions are linked to cytoskeleton. Am J Physiol 253:C171-C175
    • (1987) Am J Physiol , vol.253
    • Madara, J.L.1
  • 38
    • 0031943571 scopus 로고    scopus 로고
    • Regulation of the movement of solutes across tight junctions
    • Madara JL (1998) Regulation of the movement of solutes across tight junctions. Annu Rev Physiol 60:143-159
    • (1998) Annu Rev Physiol , vol.60 , pp. 143-159
    • Madara, J.L.1
  • 39
    • 0023631266 scopus 로고
    • Alteration of tight junction structure and permeability by cytoskeletal contraction
    • Madara JL, Moore R, Carlson S (1987) Alteration of tight junction structure and permeability by cytoskeletal contraction. Am J Physiol 253:C854-C861
    • (1987) Am J Physiol , vol.253
    • Madara, J.L.1    Moore, R.2    Carlson, S.3
  • 40
    • 0023949917 scopus 로고
    • Functional coupling of tight junctions and microfilaments in T84 mono-layers
    • Madara JL, Stafford J, Barenberg D, Carlson S (1988) Functional coupling of tight junctions and microfilaments in T84 mono-layers. Am J Physiol 254:G416-G423
    • (1988) Am J Physiol , vol.254
    • Madara, J.L.1    Stafford, J.2    Barenberg, D.3    Carlson, S.4
  • 42
    • 0022748005 scopus 로고
    • The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral domains of MDCK cells
    • Meer G van, Simons K (1986) The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral domains of MDCK cells EMBO J 5: 1455-1464
    • (1986) EMBO J , vol.5 , pp. 1455-1464
    • Van Meer, G.1    Simons, K.2
  • 43
    • 0033582334 scopus 로고    scopus 로고
    • Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
    • Morita K, Furuse M, Fujimoto K, Tsukita S (1999a) Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci USA 96:511-516
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 511-516
    • Morita, K.1    Furuse, M.2    Fujimoto, K.3    Tsukita, S.4
  • 44
    • 0033523758 scopus 로고    scopus 로고
    • Endothelial claudin: Claudin-5/TMVCF constitutes tight junction strands in endothelial cells
    • Morita K, Sasaki H, Furuse M, Tsukita S (1999b) Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol 147:185-194
    • (1999) J Cell Biol , vol.147 , pp. 185-194
    • Morita, K.1    Sasaki, H.2    Furuse, M.3    Tsukita, S.4
  • 46
    • 0026742367 scopus 로고
    • Changes in intracellular calcium during the development of epithelial polarity and junctions
    • Nigam SK, Rodriguez-Boulan E, Silver RB (1992) Changes in intracellular calcium during the development of epithelial polarity and junctions. Proc Natl Acad Sci USA 89:6162-6166
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6162-6166
    • Nigam, S.K.1    Rodriguez-Boulan, E.2    Silver, R.B.3
  • 48
    • 0033516481 scopus 로고    scopus 로고
    • Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex
    • Pece S, Chiariello M, Murga C, Gutkind JS (1999) Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex. J Biol Chem 274:19347-19351
    • (1999) J Biol Chem , vol.274 , pp. 19347-19351
    • Pece, S.1    Chiariello, M.2    Murga, C.3    Gutkind, J.S.4
  • 49
    • 0024513912 scopus 로고
    • New mammary epithelial and fibroblastic cell clones in coculture form structures competent to differentiate functionally
    • Reichmann E, Ball R, Groner B, Friis RR (1989) New mammary epithelial and fibroblastic cell clones in coculture form structures competent to differentiate functionally. J Cell Biol 108: 1127-1138
    • (1989) J Cell Biol , vol.108 , pp. 1127-1138
    • Reichmann, E.1    Ball, R.2    Groner, B.3    Friis, R.R.4
  • 52
    • 0032555295 scopus 로고    scopus 로고
    • i2 in the maintenance and biogenesis of epithelial cell tight junctions
    • i2 in the maintenance and biogenesis of epithelial cell tight junctions. J Biol Chem 273:21629-21633
    • (1998) J Biol Chem , vol.273 , pp. 21629-21633
    • Saha, C.1    Nigam, S.K.2    Denker, B.M.3
  • 53
    • 0032550221 scopus 로고    scopus 로고
    • Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
    • Saitou M, Fujiimoto K, Doi Y, Itoh M, Fujimoto T, Furuse M, Takano H, Noda T, Tsukita S (1998) Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol 141:397-408
    • (1998) J Cell Biol , vol.141 , pp. 397-408
    • Saitou, M.1    Fujiimoto, K.2    Doi, Y.3    Itoh, M.4    Fujimoto, T.5    Furuse, M.6    Takano, H.7    Noda, T.8    Tsukita, S.9
  • 54
    • 0028931103 scopus 로고
    • Evidence that tyrosine phosphorylation may increase tight junction permeability
    • Staddon JM, Herrenknecht K, Smales C, Rubin LL (1995) Evidence that tyrosine phosphorylation may increase tight junction permeability. J Cell Sci 108:609-619
    • (1995) J Cell Sci , vol.108 , pp. 609-619
    • Staddon, J.M.1    Herrenknecht, K.2    Smales, C.3    Rubin, L.L.4
  • 55
    • 0016140812 scopus 로고
    • Structure and function of intercellular junctions
    • Staehelin LA (1974) Structure and function of intercellular junctions. Int Rev Cytol 39:191-283
    • (1974) Int Rev Cytol , vol.39 , pp. 191-283
    • Staehelin, L.A.1
  • 56
    • 0028289263 scopus 로고
    • Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells
    • Stevenson BR, Begg DA (1994) Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J Cell Sci 107:367-375
    • (1994) J Cell Sci , vol.107 , pp. 367-375
    • Stevenson, B.R.1    Begg, D.A.2
  • 57
    • 0023030826 scopus 로고
    • Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia
    • Stevenson BR, Silicano JD, Mooseker M, Goodenough DA (1986) Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J Cell Biol 103:755-766
    • (1986) J Cell Biol , vol.103 , pp. 755-766
    • Stevenson, B.R.1    Silicano, J.D.2    Mooseker, M.3    Goodenough, D.A.4
  • 58
    • 0029041046 scopus 로고
    • Regulated assembly of tight junctions by protein kinase C
    • Stuart RO, Nigam SK (1995) Regulated assembly of tight junctions by protein kinase C. Proc Natl Acad Sci USA 92: 6072-6076
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6072-6076
    • Stuart, R.O.1    Nigam, S.K.2
  • 60
    • 0029967354 scopus 로고    scopus 로고
    • Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores
    • Stuart RO, Sun A, Bush KT, Nigam SK (1996) Dependence of epithelial intercellular junction biogenesis on thapsigargin-sensitive intracellular calcium stores. J Biol Chem 271: 13636-13641
    • (1996) J Biol Chem , vol.271 , pp. 13636-13641
    • Stuart, R.O.1    Sun, A.2    Bush, K.T.3    Nigam, S.K.4
  • 61
    • 0033004247 scopus 로고    scopus 로고
    • Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins
    • Tsukamoto T, Nigam SK (1999) Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. Am J Physiol 45:F737-F750
    • (1999) Am J Physiol , vol.45
    • Tsukamoto, T.1    Nigam, S.K.2
  • 62
    • 0033168966 scopus 로고    scopus 로고
    • Occludin and claudins in tight-junction strands. Leading or supporting players?
    • Tsukita S, Furuse M (1999) Occludin and claudins in tight-junction strands. Leading or supporting players? Trends Cell Biol 9:268-273
    • (1999) Trends Cell Biol , vol.9 , pp. 268-273
    • Tsukita, S.1    Furuse, M.2
  • 64
    • 0033521140 scopus 로고    scopus 로고
    • Protein interactions at the tight junction. Actin has multiple binding partners and ZO-1 form independent complexes with ZO-2 and ZO-3
    • Wittchen ES, Haskins J, Stevenson BR (1999) Protein interactions at the tight junction. Actin has multiple binding partners and ZO-1 form independent complexes with ZO-2 and ZO-3. J Biol Chem 274:35179-35185
    • (1999) J Biol Chem , vol.274 , pp. 35179-35185
    • Wittchen, E.S.1    Haskins, J.2    Stevenson, B.R.3
  • 65
    • 0028246186 scopus 로고
    • Modulation of tight junction structure in blood-brain-barrier endothelial cells. Effect of tissue culture second messengers and cocultured astrocytes
    • Wolburg H, Neuhaus J, Kniesel U, Krauss B, Schmid EM, Ocalan M, Farrell C, Risau W (1994) Modulation of tight junction structure in blood-brain-barrier endothelial cells. Effect of tissue culture second messengers and cocultured astrocytes. J Cell Sci 107:1347-1357
    • (1994) J Cell Sci , vol.107 , pp. 1347-1357
    • Wolburg, H.1    Neuhaus, J.2    Kniesel, U.3    Krauss, B.4    Schmid, E.M.5    Ocalan, M.6    Farrell, C.7    Risau, W.8
  • 66
    • 0031425958 scopus 로고    scopus 로고
    • Phosphorylation of occludin correlates with occludin localization and function at the tight junction
    • Wong V (1997) Phosphorylation of occludin correlates with occludin localization and function at the tight junction. Am J Physiol 42:C1859-C1867
    • (1997) Am J Physiol , vol.42
    • Wong, V.1


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