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Volumn 21, Issue 5, 2000, Pages 705-715

Antinociceptive and behavioral activation responses elicited by D-Pro2-Endomorphin-2 in the ventrolateral periaqueductal gray are sensitive to sex and gonadectomy differences in rats

Author keywords

Adult gonadectomy; Antinociception; Behavioral activation; D Pro2 Endomorphin 2; Locomotor activity; Morphine; Pain; Sex differences

Indexed keywords

ENDORPHIN DERIVATIVE; MORPHINE;

EID: 0034080095     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(00)00191-1     Document Type: Article
Times cited : (11)

References (66)
  • 1
    • 0024396518 scopus 로고
    • Sex-related differences in the effects of morphine and stress on visceral pain
    • Baamonde A.I., Hidalgo A., Andres-Trelles F. Sex-related differences in the effects of morphine and stress on visceral pain. Neuropharmacology. 28:1989;967-970.
    • (1989) Neuropharmacology , vol.28 , pp. 967-970
    • Baamonde, A.I.1    Hidalgo, A.2    Andres-Trelles, F.3
  • 3
    • 0025855391 scopus 로고
    • Integration of somatic and autonomic reactions within the midbrain periaqueductal gray: Viscerotopic, somatotopic, and functional organization
    • Bandler R., Carrive P., Zhang S.P. Integration of somatic and autonomic reactions within the midbrain periaqueductal gray viscerotopic, somatotopic, and functional organization . Prog Brain Res. 87:1992;269-305.
    • (1992) Prog Brain Res , vol.87 , pp. 269-305
    • Bandler, R.1    Carrive, P.2    Zhang, S.P.3
  • 4
    • 0030741986 scopus 로고    scopus 로고
    • Sex differences in opioid antinociception
    • Bartok R. E, Craft R. M. Sex differences in opioid antinociception. J Pharmacol Exp Ther 1997;282:769-778.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 769-778
    • Bartok, R.E.1    Craft, R.M.2
  • 5
    • 0021857965 scopus 로고
    • The midbrain periaqueductal gray in the rat. I. Nuclear volume, cell number, density, orientation and regional subdivisions
    • Beitz A.J. The midbrain periaqueductal gray in the rat. I. Nuclear volume, cell number, density, orientation and regional subdivisions. J Comp Neurol. 237:1985;445-459.
    • (1985) J Comp Neurol , vol.237 , pp. 445-459
    • Beitz, A.J.1
  • 6
    • 0021880479 scopus 로고
    • The midbrain periaqueductal gray in the rat. II. A Golgi analysis
    • Beitz A.J., Shepard R.D. The midbrain periaqueductal gray in the rat. II. A Golgi analysis. J Comp Neurol. 237:1985;460-475.
    • (1985) J Comp Neurol , vol.237 , pp. 460-475
    • Beitz, A.J.1    Shepard, R.D.2
  • 7
    • 0025737888 scopus 로고
    • Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus: Studies with the partial μ-1 agonist ethylketocyclazocine
    • Bodnar R.J., Paul D., Pasternak G.W. Synergistic analgesic interactions between the periaqueductal gray and the locus coeruleus studies with the partial μ-1 agonist ethylketocyclazocine . Brain Res. 558:1991;224-230.
    • (1991) Brain Res , vol.558 , pp. 224-230
    • Bodnar, R.J.1    Paul, D.2    Pasternak, G.W.3
  • 8
    • 0024161140 scopus 로고
    • Organismic variables and pain-inhibition: Roles of gender and aging
    • Bodnar R.J., Romero M.T., Kramer E. Organismic variables and pain-inhibition roles of gender and aging . Brain Res Bull. 21:1988;947-953.
    • (1988) Brain Res Bull , vol.21 , pp. 947-953
    • Bodnar, R.J.1    Romero, M.T.2    Kramer, E.3
  • 9
    • 0023943833 scopus 로고
    • Role of mu1 opiate receptors in supraspinal opiate analgesia: A microinjection study
    • Bodnar R.J., Williams C.L., Lee S.J., Pasternak G.W. Role of mu1 opiate receptors in supraspinal opiate analgesia a microinjection study . Brain Res. 447:1988;25-34.
    • (1988) Brain Res , vol.447 , pp. 25-34
    • Bodnar, R.J.1    Williams, C.L.2    Lee, S.J.3    Pasternak, G.W.4
  • 10
    • 0032526578 scopus 로고    scopus 로고
    • Microinjection of morphine into the rostralventromedial medulla produces greater antinociception in male compared to female rats
    • Boyer J.S., Morgan M.M., Craft R.M. Microinjection of morphine into the rostralventromedial medulla produces greater antinociception in male compared to female rats. Brain Res. 796:1998;315-318.
    • (1998) Brain Res , vol.796 , pp. 315-318
    • Boyer, J.S.1    Morgan, M.M.2    Craft, R.M.3
  • 11
    • 0019385568 scopus 로고
    • Effects of intraventricular morphine and enkephalins on locomotor activity in nondependent, morphine-dependent and postdependent rats
    • Brady L.S., Holtzman S.J. Effects of intraventricular morphine and enkephalins on locomotor activity in nondependent, morphine-dependent and postdependent rats. J Pharmacol Exp Ther. 218:1981;613-620.
    • (1981) J Pharmacol Exp Ther , vol.218 , pp. 613-620
    • Brady, L.S.1    Holtzman, S.J.2
  • 13
    • 0032810110 scopus 로고    scopus 로고
    • Endomorphin-1 and endomorphin-2, endogenous ligands for the μ-opioid receptor, inhibit electrical activity of rat rostral ventrolateral medulla neurons in vitro
    • Chu X.P., Xu N.S., Li P., Wang J.Q. Endomorphin-1 and endomorphin-2, endogenous ligands for the μ-opioid receptor, inhibit electrical activity of rat rostral ventrolateral medulla neurons in vitro. Neuroscience. 93:1999;681-686.
    • (1999) Neuroscience , vol.93 , pp. 681-686
    • Chu, X.P.1    Xu, N.S.2    Li, P.3    Wang, J.Q.4
  • 14
    • 0030436883 scopus 로고    scopus 로고
    • Gender-related differences in the antinociceptive properties of morphine
    • Cicero T.J., Nock B., Meyer E.R. Gender-related differences in the antinociceptive properties of morphine. J Pharmacol Exp Ther. 279:1996;767-773.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 767-773
    • Cicero, T.J.1    Nock, B.2    Meyer, E.R.3
  • 15
    • 0030802504 scopus 로고    scopus 로고
    • Sex-related differences in morphine's antinociceptive activity: Relationship to serum and brain morphine concentrations
    • Cicero T.J., Nock B., Meyer E.R. Sex-related differences in morphine's antinociceptive activity relationship to serum and brain morphine concentrations . J Pharmacol Exp Ther. 282:1997;939-944.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 939-944
    • Cicero, T.J.1    Nock, B.2    Meyer, E.R.3
  • 16
    • 0023945582 scopus 로고
    • Cytochrome oxidase histochemistry reveals regional subdivisions in the rat periaqueductal gray
    • Conti F., Barbaresi P., Fabri M. Cytochrome oxidase histochemistry reveals regional subdivisions in the rat periaqueductal gray. Neurosci. 24:1988;629-633.
    • (1988) Neurosci , vol.24 , pp. 629-633
    • Conti, F.1    Barbaresi, P.2    Fabri, M.3
  • 17
    • 0032569709 scopus 로고    scopus 로고
    • Sex differences in cocaine- And nicotine-induced antinociception in the rat
    • Craft R.M., Milholland R.B. Sex differences in cocaine- and nicotine-induced antinociception in the rat. Brain Res. 809:1998;137-140.
    • (1998) Brain Res , vol.809 , pp. 137-140
    • Craft, R.M.1    Milholland, R.B.2
  • 19
    • 0017122352 scopus 로고
    • Analgesic effect of vaginal stimulation in rats: Modulation by graded stimulus intensity and hormones
    • Crowley W.R., Jacobs R., Volpe J., Rodriguez-Sierra J.F., Komisaruk B.R. Analgesic effect of vaginal stimulation in rats modulation by graded stimulus intensity and hormones . Physiol Behav. 16:1976;483-488.
    • (1976) Physiol Behav , vol.16 , pp. 483-488
    • Crowley, W.R.1    Jacobs, R.2    Volpe, J.3    Rodriguez-Sierra, J.F.4    Komisaruk, B.R.5
  • 20
    • 0002261078 scopus 로고
    • A method for determining loss of pain sensation
    • D'Amour F.E., Smith D.L. A method for determining loss of pain sensation. J Pharmacol Exp Ther. 72:1941;74-79.
    • (1941) J Pharmacol Exp Ther , vol.72 , pp. 74-79
    • D'Amour, F.E.1    Smith, D.L.2
  • 21
    • 0000534899 scopus 로고
    • A new technique for the investigation of some analgesic drugs on a reflexive behavior in the rat
    • Evans W.O. A new technique for the investigation of some analgesic drugs on a reflexive behavior in the rat. Psychopharmacology. 2:1961;318-325.
    • (1961) Psychopharmacology , vol.2 , pp. 318-325
    • Evans, W.O.1
  • 22
    • 0022501341 scopus 로고
    • Action at the mu receptor is sufficient to explain supraspinal analgesic effect of opiates
    • Fang F.G., Fields H.L., Lee N.M. Action at the mu receptor is sufficient to explain supraspinal analgesic effect of opiates. J Pharmacol Exp Ther. 238:1986;1039-1044.
    • (1986) J Pharmacol Exp Ther , vol.238 , pp. 1039-1044
    • Fang, F.G.1    Fields, H.L.2    Lee, N.M.3
  • 24
    • 0022348355 scopus 로고
    • Locomotor activity of rats after injection of various opioids into the nucleus accumbens and septum mediale
    • Havemann U., Kuschinsky K. Locomotor activity of rats after injection of various opioids into the nucleus accumbens and septum mediale. Naunyn Schmiedebergs Arch Pharmacol. 331:1985;175-180.
    • (1985) Naunyn Schmiedebergs Arch Pharmacol , vol.331 , pp. 175-180
    • Havemann, U.1    Kuschinsky, K.2
  • 25
    • 0027194019 scopus 로고
    • Interactions among aging, gender and gonadectomy effects upon morphine antinociception in rats
    • Islam A.K., Cooper M.L., Bodnar R.J. Interactions among aging, gender and gonadectomy effects upon morphine antinociception in rats. Physiol Behav. 54:1993;45-53.
    • (1993) Physiol Behav , vol.54 , pp. 45-53
    • Islam, A.K.1    Cooper, M.L.2    Bodnar, R.J.3
  • 26
    • 0019523684 scopus 로고
    • Locomotor activity and antinociception after putative mu, kappa, and sigma opioid receptor agonists in the rat: Influence of dopaminergic agonists and antagonists
    • Iwamoto E.T. Locomotor activity and antinociception after putative mu, kappa, and sigma opioid receptor agonists in the rat influence of dopaminergic agonists and antagonists . J Pharmacol Exp Ther. 217:1981;451-460.
    • (1981) J Pharmacol Exp Ther , vol.217 , pp. 451-460
    • Iwamoto, E.T.1
  • 27
    • 0021752408 scopus 로고
    • An assessment of the spontaneous activity of rats administered morphine, phencyclidine, or nicotine using automated and observational methods
    • Iwamoto E.T. An assessment of the spontaneous activity of rats administered morphine, phencyclidine, or nicotine using automated and observational methods. Psychopharmacology. 84:1984;374-378.
    • (1984) Psychopharmacology , vol.84 , pp. 374-378
    • Iwamoto, E.T.1
  • 28
    • 0017230095 scopus 로고
    • Morphine-induced rotation in naive nonlesioned rats
    • Jacquet Y.F., Carol M., Russell I.S. Morphine-induced rotation in naive nonlesioned rats. Science. 192:1976;261-263.
    • (1976) Science , vol.192 , pp. 261-263
    • Jacquet, Y.F.1    Carol, M.2    Russell, I.S.3
  • 29
    • 0016278017 scopus 로고
    • Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat
    • Jacquet Y.F., Lajtha A. Paradoxical effects after microinjection of morphine in the periaqueductal gray matter in the rat. Science. 185:1974;1055-1057.
    • (1974) Science , vol.185 , pp. 1055-1057
    • Jacquet, Y.F.1    Lajtha, A.2
  • 30
    • 0022558916 scopus 로고
    • Comparison of antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial, and paramedial ventral medulla in the rat as studied by the microinjection technique
    • Jensen T.S., Yaksh T.L. III. Comparison of antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal gray matter, medial, and paramedial ventral medulla in the rat as studied by the microinjection technique. Brain Res. 372:1986;301-312.
    • (1986) Brain Res , vol.372 , pp. 301-312
    • Jensen, T.S.1    Yaksh T.L. III2
  • 31
    • 0025276973 scopus 로고
    • Developmental changes in opiate-induced analgesia in deer mice: Sex and population differences
    • Kavaliers M., Innes D.G.L. Developmental changes in opiate-induced analgesia in deer mice sex and population differences . Brain Res. 516:1990;326-331.
    • (1990) Brain Res , vol.516 , pp. 326-331
    • Kavaliers, M.1    Innes, D.G.L.2
  • 32
    • 0027440509 scopus 로고
    • Sex differences in the antinociceptive effects of the enkephalinase inhibitor, SCH34826
    • Kavaliers M., Innes D.G.L. Sex differences in the antinociceptive effects of the enkephalinase inhibitor, SCH34826. Pharmacol Biochem Behav. 46:1993;777-780.
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 777-780
    • Kavaliers, M.1    Innes, D.G.L.2
  • 33
    • 0023196915 scopus 로고
    • Sex and day/night differences in opiate-induced responses of insular wild deer mice, Peromyscus maniculatis triangularis
    • Kavaliers M., Innis D.G.L. Sex and day/night differences in opiate-induced responses of insular wild deer mice, Peromyscus maniculatis triangularis. Pharmacol Biochem Behav. 27:1987;477-482.
    • (1987) Pharmacol Biochem Behav , vol.27 , pp. 477-482
    • Kavaliers, M.1    Innis, D.G.L.2
  • 34
    • 0024316843 scopus 로고
    • Roles of gender, gonadectomy, and estrous phase in the analgesic effects of intracrebroventricular morphine in rats
    • Kepler K.L., Kest B., Kiefel J.M., Cooper M.L., Bodnar R.J. Roles of gender, gonadectomy, and estrous phase in the analgesic effects of intracrebroventricular morphine in rats. Pharmacol Biochem Behav. 34:1989;119-127.
    • (1989) Pharmacol Biochem Behav , vol.34 , pp. 119-127
    • Kepler, K.L.1    Kest, B.2    Kiefel, J.M.3    Cooper, M.L.4    Bodnar, R.J.5
  • 36
    • 0026575114 scopus 로고
    • Roles of gender and gonadectomy in pilocarpine and clonidine analgesia in rats
    • Kiefel J.M., Bodnar R.J. Roles of gender and gonadectomy in pilocarpine and clonidine analgesia in rats. Pharmacol Biochem Behav. 41:1992;153-158.
    • (1992) Pharmacol Biochem Behav , vol.41 , pp. 153-158
    • Kiefel, J.M.1    Bodnar, R.J.2
  • 37
    • 0034737448 scopus 로고    scopus 로고
    • Analysis of sex and gonadectomy differences in β-endorphin antinociception elicited from the ventrolateral periaqueductal gray in rats
    • Krzanowska E, Bodnar RJ. Analysis of sex and gonadectomy differences in β-endorphin antinociception elicited from the ventrolateral periaqueductal gray in rats. Eur J Pharmacol 2000;392:157-61.
    • (2000) Eur J Pharmacol , vol.392 , pp. 157-161
    • Krzanowska, E.1    Bodnar, R.J.2
  • 38
    • 0033528449 scopus 로고    scopus 로고
    • Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats
    • Krzanowska E., Bodnar R.J. Morphine antinociception elicited from the ventrolateral periaqueductal gray is sensitive to sex and gonadectomy differences in rats. Brain Res. 821:1999;224-230.
    • (1999) Brain Res , vol.821 , pp. 224-230
    • Krzanowska, E.1    Bodnar, R.J.2
  • 39
    • 0025362802 scopus 로고
    • Estradiol induction of proenkephalin messenger RNA in hypothalamus: Dose-response and reaction to reproductive behavior in the female rat
    • Lauber A.H., Romano G.J., Mobbs C.V., Howells R.D., Pfaff D.W. Estradiol induction of proenkephalin messenger RNA in hypothalamus dose-response and reaction to reproductive behavior in the female rat . Mol Brain Res. 8:1990;47-54.
    • (1990) Mol Brain Res , vol.8 , pp. 47-54
    • Lauber, A.H.1    Romano, G.J.2    Mobbs, C.V.3    Howells, R.D.4    Pfaff, D.W.5
  • 40
    • 0032420958 scopus 로고    scopus 로고
    • Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers
    • Martin-Schild S., Gerall A.A., Kastin A.J., Zadina J.E. Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers. Peptides. 19:1998;1783-1789.
    • (1998) Peptides , vol.19 , pp. 1783-1789
    • Martin-Schild, S.1    Gerall, A.A.2    Kastin, A.J.3    Zadina, J.E.4
  • 41
    • 0033594144 scopus 로고    scopus 로고
    • Differential distribution of endomorphin-1 and endomorphin-2-like immunoreactivities in the CNS of the rodent
    • Martin-Schild S., Gerall A.A., Kastin A.J., Zadina J.E. Differential distribution of endomorphin-1 and endomorphin-2-like immunoreactivities in the CNS of the rodent. J Comp Neurol. 405:1999;450-471.
    • (1999) J Comp Neurol , vol.405 , pp. 450-471
    • Martin-Schild, S.1    Gerall, A.A.2    Kastin, A.J.3    Zadina, J.E.4
  • 42
    • 0031409080 scopus 로고    scopus 로고
    • Localization of endomorphin-2-like immunoreactivity in the rat medulla and spinal cord
    • Martin-Schild S., Zadina J.E., Gerall A.A., Vigh S., Kastin A.J. Localization of endomorphin-2-like immunoreactivity in the rat medulla and spinal cord. Peptides. 18:1997;1641-1649.
    • (1997) Peptides , vol.18 , pp. 1641-1649
    • Martin-Schild, S.1    Zadina, J.E.2    Gerall, A.A.3    Vigh, S.4    Kastin, A.J.5
  • 43
    • 0028217474 scopus 로고
    • Biphasic effects of intra-accumbens μ-opioid peptide agonist DAMGO on locomotor activities
    • Meyer M.E., McLaurin B.I., Allen M., Meyer M.E. Biphasic effects of intra-accumbens μ-opioid peptide agonist DAMGO on locomotor activities. Pharmacol Biochem Behav. 47:1994;827-831.
    • (1994) Pharmacol Biochem Behav , vol.47 , pp. 827-831
    • Meyer, M.E.1    McLaurin, B.I.2    Allen, M.3    Meyer, M.E.4
  • 44
    • 0027374242 scopus 로고
    • Behavioral effects of mu opioid agonists DAMGO, DALDA, and PL017 on locomotor activities
    • Meyer M.E., Meyer M.E. Behavioral effects of mu opioid agonists DAMGO, DALDA, and PL017 on locomotor activities. Pharmacol Biochem Behav. 46:1993;391-395.
    • (1993) Pharmacol Biochem Behav , vol.46 , pp. 391-395
    • Meyer, M.E.1    Meyer, M.E.2
  • 45
    • 0027229578 scopus 로고
    • Behavioral effects of opioid receptor agonists, DAGO, DPDPE, and DAKLI on locomotor activities
    • Meyer M.E., Meyer M.E. Behavioral effects of opioid receptor agonists, DAGO, DPDPE, and DAKLI on locomotor activities. Pharmacol Biochem Behav. 45:1993;315-320.
    • (1993) Pharmacol Biochem Behav , vol.45 , pp. 315-320
    • Meyer, M.E.1    Meyer, M.E.2
  • 46
    • 0030088064 scopus 로고    scopus 로고
    • Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception: Influence of nociceptive assay
    • Mogil J.S., Kest B., Sadowski B., Belknap J.K. Differential genetic mediation of sensitivity to morphine in genetic models of opiate antinociception influence of nociceptive assay . J Pharmacol Exp Ther. 276:1996;532-544.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 532-544
    • Mogil, J.S.1    Kest, B.2    Sadowski, B.3    Belknap, J.K.4
  • 47
    • 0029916069 scopus 로고    scopus 로고
    • Biochemical and pharmacological characterization of multiple β-endorphinergic antinociceptive systems in the rat periaqueductal gray
    • Monroe P.J., Hawranko A.A., Smith D.L., Smith D.J. Biochemical and pharmacological characterization of multiple β-endorphinergic antinociceptive systems in the rat periaqueductal gray. J Pharmacol Exp Ther. 276:1996;65-93.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 65-93
    • Monroe, P.J.1    Hawranko, A.A.2    Smith, D.L.3    Smith, D.J.4
  • 48
    • 0343617632 scopus 로고    scopus 로고
    • Beta-endorphin dose-dependently activates multiple spinopetal antinociceptive pathways after its microinjection into the rat periaqueductal gray: Comparison with those activated by morphine
    • Monroe P.J., Smith D.L., Smith D.J. Beta-endorphin dose-dependently activates multiple spinopetal antinociceptive pathways after its microinjection into the rat periaqueductal gray comparison with those activated by morphine . Analgesia. 3:1997;21-26.
    • (1997) Analgesia , vol.3 , pp. 21-26
    • Monroe, P.J.1    Smith, D.L.2    Smith, D.J.3
  • 49
    • 0029972504 scopus 로고    scopus 로고
    • Hypothalamic cellular and molecular mechanisms helping to satisfy axiomatic requirements for reproduction
    • Pfaff D.W., Kow L.M., Zhu Y.S., Scott R.E.M., Wu-Peng S.X., Dellovade T. Hypothalamic cellular and molecular mechanisms helping to satisfy axiomatic requirements for reproduction. J Neuroendocrinol. 8:1996;325-336.
    • (1996) J Neuroendocrinol , vol.8 , pp. 325-336
    • Pfaff, D.W.1    Kow, L.M.2    Zhu, Y.S.3    Scott, R.E.M.4    Wu-Peng, S.X.5    Dellovade, T.6
  • 50
    • 0001153851 scopus 로고
    • Cellular mechanisms of female reproductive behaviors
    • E. Knobil, & J. Neill. New York: Raven Press
    • Pfaff D.W., Schwartz-Giblin S. Cellular mechanisms of female reproductive behaviors. Knobil E., Neill J. The physiology of reproduction. 1988;1487-1569 Raven Press, New York.
    • (1988) The Physiology of Reproduction , pp. 1487-1569
    • Pfaff, D.W.1    Schwartz-Giblin, S.2
  • 51
    • 0345391048 scopus 로고    scopus 로고
    • Spinal analgesic action of endomorphins in acute, inflammatory, and neuropathic pain in rats
    • Przewlocka B., Mika J., Labuz D., Toth G., Przewlocki R. Spinal analgesic action of endomorphins in acute, inflammatory, and neuropathic pain in rats. Eur J Pharmacol. 367:1999;189-196.
    • (1999) Eur J Pharmacol , vol.367 , pp. 189-196
    • Przewlocka, B.1    Mika, J.2    Labuz, D.3    Toth, G.4    Przewlocki, R.5
  • 52
    • 0032484257 scopus 로고    scopus 로고
    • Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV (EC3.4.14.5) produces naloxone-reversible analgesia in rats
    • Ronai A.Z., Timar J., Mako E., et al. Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV (EC3.4.14.5) produces naloxone-reversible analgesia in rats. Life Sci. 64:1999;145-152.
    • (1999) Life Sci , vol.64 , pp. 145-152
    • Ronai, A.Z.1    Timar, J.2    Mako, E.3
  • 53
    • 0028047065 scopus 로고
    • Mu and delta opioid synergy between the periaqueductal gray and the rostro-ventral medulla
    • Rossi G.C., Pasternak G.W., Bodnar R.J. Mu and delta opioid synergy between the periaqueductal gray and the rostro-ventral medulla. Brain Res. 665:1994;85-93.
    • (1994) Brain Res , vol.665 , pp. 85-93
    • Rossi, G.C.1    Pasternak, G.W.2    Bodnar, R.J.3
  • 54
    • 0028856752 scopus 로고
    • Differential blockade of morphine and morphine-6B-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats
    • Rossi G.C., Standifer K.M., Pasternak G.W. Differential blockade of morphine and morphine-6B-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats. Neurosci Lett. 198:1995;99-102.
    • (1995) Neurosci Lett , vol.198 , pp. 99-102
    • Rossi, G.C.1    Standifer, K.M.2    Pasternak, G.W.3
  • 55
    • 0032893243 scopus 로고    scopus 로고
    • Differential involvement of μ-opioid receptor subtypes in endomorphin-1 and -2-induced antinociception
    • Sakurada S., Zadina J.E., Kastin A.J., et al. Differential involvement of μ-opioid receptor subtypes in endomorphin-1 and -2-induced antinociception. Eur J Pharmacol. 372:1999;25-30.
    • (1999) Eur J Pharmacol , vol.372 , pp. 25-30
    • Sakurada, S.1    Zadina, J.E.2    Kastin, A.J.3
  • 56
    • 0029552394 scopus 로고
    • In vivo injection of oligodeoxynucleotides to G-α subunits and supraspinal analgesia evoked by mu and delta opioid agonists
    • Sanchez-Blanquez P., Garcia-Espana A., Garzon J. In vivo injection of oligodeoxynucleotides to G-α subunits and supraspinal analgesia evoked by mu and delta opioid agonists. J Pharmacol Exp Ther. 275:1995;1590-1596.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1590-1596
    • Sanchez-Blanquez, P.1    Garcia-Espana, A.2    Garzon, J.3
  • 57
    • 0344069680 scopus 로고    scopus 로고
    • Endomorphin-1 and endomorphin-2 show differences in their activation of mu opioid receptor-regulated G proteins in supraspinal antinociception in mice
    • Sanchez-Blanquez P., Rodriguez-Diaz M., DeAntonio I., Garzon J. Endomorphin-1 and endomorphin-2 show differences in their activation of mu opioid receptor-regulated G proteins in supraspinal antinociception in mice. J Pharmacol Exp Ther. 291:1999;12-18.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 12-18
    • Sanchez-Blanquez, P.1    Rodriguez-Diaz, M.2    Deantonio, I.3    Garzon, J.4
  • 58
    • 0033537291 scopus 로고    scopus 로고
    • Modulation of endomorphin-2-induced analgesia by dipeptidyl peptidase IV
    • Shane R., Wilk S., Bodnar R.J. Modulation of endomorphin-2-induced analgesia by dipeptidyl peptidase IV. Brain Res. 815:1999;278-286.
    • (1999) Brain Res , vol.815 , pp. 278-286
    • Shane, R.1    Wilk, S.2    Bodnar, R.J.3
  • 59
    • 0023792423 scopus 로고
    • The mu receptor is responsible for descending pain inhibition originating in the periaqueductal gray region of the rat brain
    • Smith D.J., Perotti J.M., Crisp T., Cabral M.E.Y., Long J.T., Scalziti J.N. The mu receptor is responsible for descending pain inhibition originating in the periaqueductal gray region of the rat brain. Eur J Pharmacol. 156:1988;47-54.
    • (1988) Eur J Pharmacol , vol.156 , pp. 47-54
    • Smith, D.J.1    Perotti, J.M.2    Crisp, T.3    Cabral, M.E.Y.4    Long, J.T.5    Scalziti, J.N.6
  • 60
    • 0026449020 scopus 로고
    • Antinociception from the administration of β-endorphin into the periaqueductal gray is enhanced whereas that of morphine is inhibited by barbiturate anesthesia
    • Smith D.J., Robertson B., Monroe P.J. Antinociception from the administration of β-endorphin into the periaqueductal gray is enhanced whereas that of morphine is inhibited by barbiturate anesthesia. Neurosci Lett. 146:1992;143-146.
    • (1992) Neurosci Lett , vol.146 , pp. 143-146
    • Smith, D.J.1    Robertson, B.2    Monroe, P.J.3
  • 61
    • 0026445431 scopus 로고
    • Opioid receptors mediating antinociception from β-endorphin and morphine in the periaqueductal gray
    • Smith D.J., Robertson B., Monroe P.J., Leedham J.A., Cabral J.D.Y. Opioid receptors mediating antinociception from β-endorphin and morphine in the periaqueductal gray. Neuropharmacology. 31:1992;1137-1150.
    • (1992) Neuropharmacology , vol.31 , pp. 1137-1150
    • Smith, D.J.1    Robertson, B.2    Monroe, P.J.3    Leedham, J.A.4    Cabral, J.D.Y.5
  • 62
    • 0029837191 scopus 로고    scopus 로고
    • Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits
    • Standifer K.M., Rossi G.C., Pasternak G.W. Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits. Mol Pharmacol. 50:1996;293-298.
    • (1996) Mol Pharmacol , vol.50 , pp. 293-298
    • Standifer, K.M.1    Rossi, G.C.2    Pasternak, G.W.3
  • 63
    • 0030863633 scopus 로고    scopus 로고
    • Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2
    • Stone L.S., Fairbanks C.A., Laughlin T.M., et al. Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2. Neuroreport. 8:1997;3131-3135.
    • (1997) Neuroreport , vol.8 , pp. 3131-3135
    • Stone, L.S.1    Fairbanks, C.A.2    Laughlin, T.M.3
  • 65
    • 0032834128 scopus 로고    scopus 로고
    • Release of endomorphin-2 like substances from the rat spinal cord
    • Williams C.A., Wu S.Y., Dun S.L., Kwok E.H., Dun N.J. Release of endomorphin-2 like substances from the rat spinal cord. Neurosci Lett. 273:1999;25-28.
    • (1999) Neurosci Lett , vol.273 , pp. 25-28
    • Williams, C.A.1    Wu, S.Y.2    Dun, S.L.3    Kwok, E.H.4    Dun, N.J.5
  • 66
    • 0030933655 scopus 로고    scopus 로고
    • A potent and selective endogenous agonist for the μ-opiate receptor
    • Zadina J.E., Hackler L., Ge L.-J., Kastin A.J. A potent and selective endogenous agonist for the μ-opiate receptor. Nature. 386:1997;499-502.
    • (1997) Nature , vol.386 , pp. 499-502
    • Zadina, J.E.1    Hackler, L.2    Ge, L.-J.3    Kastin, A.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.