Activity of hindlimb motor units during locomotion in the conscious rat

Journal of Neurophysiology

Volumn 83, Issue 4, 2000, Pages 2002-2011

  Gorassini, Monica ^a,c   Eken, Torsten ^b   Bennett, David J ^a,c   Kiehn, Ole ^a   Hultborn, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF OSLO   (Norway)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROMYOGRAPHY; FAST MUSCLE; GASTROCNEMIUS MUSCLE; LOCOMOTION; MALE; MOTONEURON; MOTOR NERVE CONDUCTION; MOTOR UNIT; NONHUMAN; PRIORITY JOURNAL; RAT; SLOW MUSCLE; SOLEUS MUSCLE; WALKING;

EID: 0034077940     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.2000.83.4.2002     Document Type: Article

References (37)

1. BENNETT, D. J., HULTBORN, H., FEDIRCHUCK, B., AND GORASSINI, M. Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats. J. Neurophysiol. 80: 2023-2037, 1998.
2. BERTRAND, S. AND CAZALETS, J.-R. Postinhibitory rebound during locomotor-like activity in the neonatal rat. J. Neurophysiol. 79: 342-351, 1998.
3. BINDER, M. D., HECKMAN, C. J., AND POWERS, R. K. The physiological control of motoneuron activity. In: Handbook of Physiology. New York: Oxford Univ. Press., 1996, sect. 12, p. 3-53.
4. BROWNSTONE, R. M., GOSSARD, J.-P., AND HULTBORN, H. Voltage-dependent excitation of motoneurones from spinal locomotor centres in the cat. Exp. Brain Res. 102: 34-44, 1994.
5. BROWNSTONE, R. M., JORDAN, L. M., KRIELLARS, D. J., AND SHEFCHYK, S. J. On the regulation of repetitive firing in lumbar motoneurones during fictive locomotion in the cat. Exp. Brain Res. 90: 441-455, 1992.
6. BURKE, R. E., RUDOMIN, P., AND ZAJAC, F. E. Catch property in single mammalian motor units. Science 168: 122-124, 1970.
7. CHAMBERLAIN, S. AND LEWIS, D. M. Contractile characteristics and innervation ratio of rat soleus motor units. J. Physiol. (Lond.) 412: 1-21, 1989.
8. DERUITER, C. J., DE HAAN, A., AND SARGEANT, A. J. Fast-twitch muscle unit properties in different rat medial gastrocnemius muscle compartments. J. Neurophysiol. 75: 2243-54, 1996.
9. DESERRES, S. J., YANG, J. F., AND PATRICK, S. K. Mechanism for reflex reversal during walking in human tibialis anterior muscle revealed by single motor unit recordings. J. Physiol. (Lond.) 488: 249-58, 1995.
10. EKEN, T. Spontaneous electromyographic activity in adult rat soleus muscle. J. Neurophysiol. 80: 365-376, 1998.
11. ENGLISH, A. W. AND LETBETTER, W. D. Anatomy and innervation patterns of cat lateral gastrocnemius and plantar muscles. Am. J. Anat. 164: 67-77, 1982.
12. FULTON, B. P. AND WALTON, K. Electrophysiological properties of neonatal rat motoneurons studied in vitro. J. Physiol. (Lond.) 370: 651-678, 1986.
13. GILLESPIE, M. J., GORDON, T., AND MURPHY, P. R. Motor units and histochemistry in rat gastrocnemius and soleus muscles: evidence for dissociation of physiological and histochemical properties after re-innervation. J. Neurophysiol. 57: 921-937, 1987.
14. GORASSINI, M., BENNETT, D. J., EKEN, T., KIEHN, O., AND HULTBORN, H. Activation patterns of hindlimb motor units in the awake rat and their relation to motoneuron intrinsic properties. J. Neurophysiol. 82: 709-717, 1999.
15. GORASSINI, M., KIEHN, O., BENNETT, D. J., AND HULTBORN, H. Hindlimb motor unit activity during locomotion in the awake rat. Soc. Neurosci. Abstr. 20: 173.18, 1995.
16. GORASSINI, M., PROCHAZKA, A., HIEBERT, G., AND GAUTHIER, M.J.A. Corrective responses to loss of ground support during walking. I. Intact cats. J. Neurophysiol. 71: 603-610, 1994.
17. GRANIT, R., KERNELL, D., AND SHORTESS, G. K. Quantitative aspects of repetitive firing of mammalian motoneurons, caused by injected currents. J. Physiol. (Lond.) 168: 911-931, 1963a.
18. GRANIT, R., KERNELL, D., AND SMITH, R. S. Delayed depolarization and the repetitive response to intracellular stimulation of mammalian motoneurones. J. Physiol. (Lond.) 168: 890-910, 1963b.
19. GRIMBY, L. Firing properties of single human motor units during locomotion. J. Physiol. (Lond.) 346: 195-202, 1984.
20. GRUNER, J. A., ALTMAN, J., AND SPIVACK, N. Effects of arrested cerebellar development on locomotor function in the rat. Exp. Brain Res. 40: 361-373, 1980.
21. HENNIG, R. AND LØMO, T. Firing patterns of motor units in normal rats. Nature 314: 164-166, 1985.
22. HOCHMAN, S. AND SCHMIDT, B. J. Whole cell recordings of lumbar motoneurons during locomotor-like activity in the in vitro neonatal rat spinal cord. J. Neurophysiol. 79: 743-752, 1998.
23. HOPPER, J. A., SUGANO, N., LOEB, G. E., MARKS, W. B., O'DONOVAN, M. J. AND PRATT, C. A. Cat hindlimb motoneurons during locomotion. II. Normal activity patterns. J. Neurophysiol. 57: 530-553, 1987.
24. JAKOBSSON, F., BORG, K., EDSTROM, L., AND GRIMBY, L. Use of motor units in relation to muscle fiber type and size in man. Muscle Nerve 11: 1211-1218, 1988.
25. KIEHN, O. AND KJAERULFF, O. Distribution of central pattern generators for rhythmic motor outputs in the spinal cord of limbed vertebrates. Ann. NY Acad. Sci. 840: 110-129, 1998.
26. KRAWITZ, S., FEDIRCHUCK, B., DAI, Y., JORDAN, L. M., AND MCCREA, D. A. Locomotion hyperpolarizes the voltage thresholds of cat lumbar motoneurones. Soc. Neurosci. Abstr. 23: 298.4, 1997.
27. LLINÁS, R. AND YAROM, Y. Electrophysiology of mammalian inferior olivary neurons in vitro. Different types of voltage-dependent ionic conductances. J. Physiol. (Lond.) 315: 549-567, 1981.
28. MACLEAN, J. N., SCHMIDT, B. J., AND HOCHMAN, S. NMDA receptor activation triggers voltage oscillations, plateau potentials and bursting in neonatal rat lumbar motoneurons in vivo. Eur. J. Neurosci. 9: 2702-2711, 1997.
29. OGAWA, Y., OKABE, H., YAMAUCHI, H., YONEMOTO, K., AND KURATA, H. Firing rate and recruitment order of single motor units in man during walking on treadmill. In: Neurobiological Basis of Human Locomotion, edited by M. Shimamura, S. Grillner, and V. R. Edgerton. Tokyo, Japan: Japan Scientific Societies Press, 1991, p. 371-378.
30. ORSAL, D., PERRET, C., AND CABELGUEN, J.-M. Evidence of rhythmic inhibitory synaptic influences in hindlimb motoneurons during fictive locomotion in the thalamic cat. Exp. Brain Res. 64: 217-224, 1986.
31. RUSSO, R. E. AND HOUNSGAARD, J. Burst-generating neurons in the dorsal horn in an in vitro preparation of the turtle spinal cord. J. Physiol. (Lond.) 493: 55-66, 1996.
32. SEVERIN, F. V., SHIK, M. L., AND ORLOVSKII, G. N. Work of the muscles and single motor neurones during controlled locomotion. Biofizika 12: 762-772, 1967.
33. STEIN, R. B. AND PARMIGGIANI, F. Optimal motor patterns for activating mammalian muscle. Brain Res. 175: 372-376, 1979.
34. TANSEY, K. E. AND BOTTERMAN, B. R. Activation of type-identified motor units during centrally evoked contractions in the cat medial-gastrocnemius muscle. II. Motoneuron firing rate modulation. J. Neurophysiol. 75: 38-50, 1996.
35. TÖTÖSY DE ZEPETNEK, J., ZUNG, H. V., ERDEBIL, S., AND GORDON, T. Motor-unit categorization based on contractile and histochemical properties: a glycogen depletion analysis of normal and reinnervated rat tibialis anterior muscle. J. Neurophysiol. 67: 1404-1415, 1992.
36. VANDEN NOVEN, S., GARDINER, P. F., AND SEBURN, K. L. Motoneurons innervating two regions of rat medial gastrocnemius muscle with differing contractile and histochemical properties. Acta Anat. 150: 282-293, 1994.
37. ZAJAC, F. E. AND YOUNG, J. L. Discharge properties of hindlimb motoneurons in decerebrate cats during locomotion induced by mesencephalic stimulation. J. Neurophysiol. 43: 1221-1235, 1980.