Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts

Journal of Bone and Mineral Research

Volumn 15, Issue 4, 2000, Pages 650-662

  Woo, Je Tae ^a,b   Kasai, Shinya ^c   Stern, Paula H ^b   Nagai, Kazuo ^c  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b NORTHWESTERN UNIVERSITY   (United States)

^c NONE

Author keywords

Actin ring; Bone resorption; Compactin; Fusion; Osteoclast

Indexed keywords

ACTIN; CASPASE INHIBITOR; COMPACTIN; FARNESYL DIPHOSPHATE; FARNESYL TRANS TRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INTERLEUKIN 1BETA; LACTONE; SQUALENE;

APOPTOSIS; ARTICLE; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL FUSION; CHOLESTEROL SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HEMATOPOIESIS; HUMAN; HUMAN CELL; OSTEOCLAST; OSTEOLYSIS; PRENYLATION;

EID: 0034062795     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2000.15.4.650     Document Type: Article

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