Crystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine protease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 5, 2000, Pages 2235-2240

  Kagawa, Todd F ^a   Cooney, Jakki C ^c   Baker, Heather M ^a   McSweeney, Sean ^d   Liu, Mengyao ^e,f   Gubba, Siddeswar ^e   Musser, James M ^e,f   Baker, Edward N ^a,b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c MASSEY UNIVERSITY   (New Zealand)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^e BAYLOR COLLEGE OF MEDICINE   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CYSTEINE PROTEINASE; ENZYME PRECURSOR; EXOTOXIN; INTEGRIN; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; CRYSTAL STRUCTURE; NECROTIZING FASCIITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN STRUCTURE; STREPTOCOCCUS; STREPTOCOCCUS PYOGENES;

BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; ENZYME PRECURSORS; INTEGRINS; MODELS, MOLECULAR; PROTEIN CONFORMATION; STREPTOCOCCUS PYOGENES;

BACTERIA (MICROORGANISMS); MAMMALIA; STREPTOCOCCUS PYOGENES; STREPTOCOCCUS SP. 'GROUP A';

EID: 0034058370     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040549997     Document Type: Article

References (46)

1. Quinn, R. W. (1989) Rev. Infect. Dis. 11, 928-953.
2. Proft, T., Moffatt, S. L., Berkhan, C. J. & Fraser, J. D. (1999) J. Exp. Med. 189, 89-101.
3. Musser, J. M. (1997) in Superantigens: Molecular Biology, Immunology, and Relevance to Human Disease, eds. Leung, D. Y. M., Huber, B. T. & Schlievert, P. M. (Dekker, New York), pp. 281-310.
4. Musser, J. M., Hauser, A. R., Kim, M., Schlievert, P. M., Nelson, K. & Selander, R. K (1991) Proc. Natl. Acad. Sci. USA 88, 2668-2672.
5. Kapur, V., Topouzis, S., Majesky, M. W., Li, L.-L., Hamrick, M. R., Hamill, R. J., Patti, J. M. & Musser, J. M. (1993) Microb. Pathog. 15, 327-346.
6. Lukomski, S., Sreevatsan, S., Amberg, C., Reichardt, W., Woischnik, M., Podbielski, A. & Musser, J. M. (1997) J. Clin. Invest. 99, 2574-2580.
7. Kapur, V., Majesky, M. W., Li, L.-L., Black, R. A. & Musser, J. M. (1993) Proc. Natl. Acad. Sci. USA 90, 7676-7680.
8. Wolf, B. B., Gibson, C. A., Kapur, V., Hussaini, I. M., Musser, J. M. & Gonias, S. L. (1994) J. Biol. Chem. 269, 30682-30687.
9. Herwald, H., Collin, M., Muller-Esterl, W. & Bjorck, L. (1996) J. Exp. Med. 184, 1-9.
10. Burns, E. H., Jr., Marciel, A. M. & Musser, J. M. (1996) Infect. Immun. 64, 4744-4750.
11. Kellner, A. & Robertson, T. (1954) J. Exp. Med. 99, 495-504.
12. Kuo, C.-F., Wu, J.-J., Tsai, P.-J., Kao, F.-J., Lei, H.-Y., Lin, M. T. & Lin, Y.-S. (1999) Infect. Immun. 67, 126-130.
13. Stockbauer, K. E., Magoun, L., Liu, M., Burns, E. H., Jr., Gubba, S., Renish, S., Pan, X., Bodary, S. C., Baker, E., Coburn, J., et al. (1999) Proc. Natl. Acad. Sci. USA 96, 242-247.
14. Elliott, S. D. (1945) J. Exp. Med. 81, 573-592.
15. Rawlings, N. D. & Barrett, A. J. (1994) Methods Enzymol. 244, 461-486.
16. Tai, J. Y., Kortt, A. A., Liu, T.-Y. & Elliott, S. D. (1976) J. Biol. Chem. 251, 1955-1959.
17. Berti, P. J. & Storer, A. C. (1995) J. Mol. Biol. 246, 273-283.
18. Cygler, M., Sivaraman, J., Grochulski, P., Coulombe, R., Storer, A. C. & Mort, J. S. (1996) Structure (London) 4, 405-416.
19. Sivaraman, J., Lalumiere, M., Menard, R. & Cygler, M. (1999) Protein Sci. 8, 283-290.
20. Coulombe, R., Grochulski, P., Sivaraman, J., Menard, R., Mort, J. S. & Cygler, M. (1996) EMBO J. 15, 5492-5503.
21. Musser, J. M., Stockbauer, K., Kapur, V. & Rudgers, G. W. (1996) Infect. Immun. 64, 1913-1917.
22. Gubba, S., Low, D. E. & Musser, J. M. (1998) Infect. Immun. 66, 765-770.
23. Hendrickson, W. A., Horton, J. R. & LeMaster, D. M. (1990) EMBO J. 9, 1665-1672.
24. Otwinowski, Z. & Minor, W. (1997) Methods Enzymol. 276, 307-326.
25. Collaborative Computational Project Number 4 (1994) Acta Crystallogr. D 50, 760-763.
26. Terwilliger, T. C. & Berendzen, J. (1999) Acta Crystallogr. D 55, 849-861.
27. De La Fortelle, E. & Bricogne, G. (1997) Methods Enzymol. 276, 472-494.
28. Petrakis, A., Morris, R. & Lamzin, V. S. (1999) Nat. Struct. Biol. 6, 458-463.
29. Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119.
30. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, M., Pannu, N. S., et al. (1998) Acta Crystallogr. D 54, 905-921.
31. Brunger, A. T. (1992) Nature (London) 355, 472-475.
32. Engh, R. A. & Huber, R. (1991) Acta Crystallogr. A 47, 392-400.
33. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
34. Merritt, E. A. & Bacon, D. J. (1997) Methods Enzymol. 277, 505-524.
35. Baker, E. N. (1980) J. Mol. Biol. 141, 441-484.
36. Tao, K., Stearns, N. A., Dong, J. & Sahagian, G. G. (1994) Arch. Biochem. Biophys. 311, 19-27.
37. Doran, J. D., Nomizu, M., Takebe, S., Menard, R., Griffith, D. & Ziomek, E. (1999) Eur. J. Biochem. 263, 145-151.
38. Gubba, S., Cipriano, V. & Musser, J. M. (2000) Infect. Immun., in press.
39. Vernet, T., Tessier, D. C., Chatellier, J., Plouffe, C., Lee, T. S., Thomas, D. Y., Storer, A. C. & Menard, R. (1995) J. Biol. Chem. 270, 16645-16652.
40. Guarné, A., Tormo, J., Kirchweger, R., Pfistermueller, D., Fita, I. & Skern, T. (1998) EMBO J. 17, 7469-7479.
41. Odagaki, Y., Hayashi, A., Okada, K., Hirotsu, K., Kabashima, T., Ito, K., Yoshimoto, T., Tsuru, D., Sato, M. & Clardy, J. (1999) Structure (London) 7, 399-411.
42. Wilson, K. P., Black, J.-A. F., Thomson, J. A., Kim, E. E., Griffith, J. P., Navia, M. A., Murcko, M. A., Chambers, S. P., Aldape, R. A., Raybuck, S. A. & Livingston, D. J. (1994) Nature (London) 370, 270-275.
43. Varughese, K. I., Su, Y., Cromwell, D., Hasnain, S. & Xuong, N-H. (1992) Biochemistry 31, 5172-5176.
44. Wickham, T. J., Mathias, P., Cheresh, D. A. & Nemerow, G. R. (1993) Cell 73, 309-319.
45. Bergelson, J. M. & Hemler, M. E. (1995) Curr. Biol. 5, 615-617.
46. Logan, D., Abu-Ghazaleh, R., Blakemore, W., Curry, S., Jackson, T., King, A., Lea, S., Lewis, R., Newman, J., Parry, N., et al. (1993) Nature (London) 362, 566-568.