Structure of the foot-and-mouth disease virus leader protease: A papain-like fold adapted for self-processing and eIF4G recognition

EMBO Journal

Volumn 17, Issue 24, 1998, Pages 7469-7479

  Guarné, Alba ^a   Tormo, José ^a   Kirchweger, Regina ^b,c   Pfistermueller, Doris ^b   Fita, Ignasi ^a   Skern, Tim ^a  

^a CSIC   (Spain)

^b UNIVERSITY OF VIENNA   (Austria)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Crystallography; Cysteine proteases; Picornavirus; RNA viruses; Translational control

Indexed keywords

CELL PROTEIN; CYSTEINE PROTEINASE; INITIATION FACTOR; INITIATION FACTOR 4 G; PAPAIN; PROTEIN; UNCLASSIFIED DRUG; VIRUS ENZYME;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; FOOT AND MOUTH DISEASE; HOST CELL; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; RNA TRANSLATION; RNA VIRUS; STEREOCHEMISTRY; VIRUS REPLICATION;

AMINO ACID SEQUENCE; APHTHOVIRUS; CATALYTIC DOMAIN; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENDOPEPTIDASES; EUKARYOTIC INITIATION FACTOR-4G; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PAPAIN; PEPTIDE INITIATION FACTORS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

EUKARYOTA; FOOT-AND-MOUTH DISEASE VIRUS; PICORNAVIRIDAE; RNA VIRUSES;

EID: 0032534805     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.24.7469     Document Type: Article

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