Increased serum nitrate concentration in cardiac transplant patients: A marker for acute allograft cellular rejection

Transplantation

Volumn 61, Issue 5, 1996, Pages 745-749

  Benvenuti, Christophe ^a,b   Bories, Phuong Nhi ^a   Loisance, Daniel ^b  

^a Hopital Albert Chenevier   (France)

^b HENRI MONDOR HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT; NITRATE; PREDNISONE;

ARTICLE; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY INFILTRATE; MAJOR CLINICAL STUDY; POSTOPERATIVE COMPLICATION; PREDICTION; PRIORITY JOURNAL;

GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 9044246270     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199603150-00013     Document Type: Article

References (21)

1. Langrehr JM, Hoffman RA, Lancaster JR, Simmons RL. Nitric oxide - a new endogenous immunomodulator. Transplantation 1993; 6: 1205.
2. Hibbs JB, Westenfelder C, Taintor R, et al. Evidence for cytokine-inducible nitric oxide synthase from L-Arginine in patients receiving interleukin 2. J Clin Invest 1992; 89: 867.
3. Langrehr JM, Hoffman RA, Billiar TR, Lee KW, Schraut WH, Simmons RL. Nitric oxide synthesis in the in-vivo allograft response: a possible regulatory mechanism. Surgery 1991; 110: 335.
4. Lancaster JR, Hibbs JB. EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages. Proc Natl Acad Sci U S A 1990; 87: 1223.
5. Yang X, Chowdhury N, Cai B, et al. Induction of mitochondrial nitric oxide synthase by cardiac allograft rejection. J Clin Invest 1994; 94: 714.
6. Langrehr JM, Murase N, Markus PM, et al. Nitric oxide production in host-versus-graft and graft-versus-host reactions in the rat. J Clin Invest 1992; 90: 679.
7. Winlaw DS, Schyvens CG, Smythe GA, et al. Urinary nitrate excretion is a non invasive indicator of acute allograft rejection and nitric oxide production in the rat. Transplantation 1994; 58: 1031.
8. The International Society for Heart Transplantation, Billingham ME, Cary RRB, Hammond ME, et al. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: heart rejection study group. J Heart Lung Transplant 1990; 9: 587.
9. Bories PN, Bories C. Nitrate determination in biological fluids by an enzymatic one-step assay with nitrate reductase. Clin Chem 1995; 6: 904.
10. Nathan CF, Hibbs JB. Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol 1991; 3: 65.
11. Winlaw DS, Smythe GA, Keogh AM, Schyvens CG, Spratt PM, MacDonald PS. Increased nitric oxide production in heart failure. Lancet 1994; 344: 373.
12. Lewis NP, Tsao PS, Rickenbacher PR, et al. Induction of inducible nitric oxide synthase (iNOS) mRNA in the human cardiac allograft is associated with impaired left ventricular contractile function. Circulation 1994; 4: 193.
13. Wu CJ, Lovett M, Wong-Lee J, et al. Cytokine gene expression in rejecting cardiac allograft. Transplantation 1992; 54: 326.
14. Lancaster JR, Jan M, Langrehr, et al. EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of heart allograft. J Biol Chem 1992; 267: 10994.
15. Devlin J, Palmer RMJ, Gonde CE, et al. Nitric oxide generation. A predictive marker of acute allograft rejection. Transplantation 1994; 58: 592.
16. Palmer RMJ, Bridge L, Foxwell NA, Moncada S. The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids. Br J Pharmacol 1992; 105: 11.
17. Balligand JL, Ungureanu D, Kelly RA, et al. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage conditioned medium. J Clin Invest 1993; 91: 2314.
18. Pinski DJ, Cai B, Yang X, Rodriguez C, Sciarra RR, Cannon PJ. Nitric oxide-dependent killing of cardiac myocytes by adjacent macrophages. Circulation 1994; 90: 192.
19. Gross WL, Balligand JL, Kelly RA, Smith TW, Ingwall JS. Nitric oxide donor alters cardiac high-energy phosphate metabolism and contractile response. Circulation 1994; 90: 193.
20. Benvenuti C, Aptecar E, Benaïem N, et al. Myocardial high-energy phosphate depletion during allograft rejection after human orthotopic heart transplantation. J Heart Lung Transplant 1994; 13: 857.
21. Wijngaard PLJ, Doorwenaard H, Van der Meulen A, et al. Cytoimmunologic monitoring as an adjunct in monitoring rejection after heart transplantation: results of a 6-year follow-up in heart transplant recipients. J Heart Lung Transplant 1994; 13: 869.