Helicobacter pylori containing only cytoplasmic urease is susceptible to acid

Infection and Immunity

Volumn 66, Issue 11, 1998, Pages 5060-5066

  Krishnamurthy, Partha ^a,b   Parlow, Mary ^b   Zitzer, Jason B ^b   Vakil, Nimish B ^c   Mobley, Harry L T ^d   Levy, Marilyn ^e   Phadnis, Suhas H ^a,b   Dunn, Bruch E ^a,b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; UREASE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ESCHERICHIA COLI; HELICOBACTER PYLORI; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

HELICOBACTER PYLORI;

EID: 0032425626     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.11.5060-5066.1998     Document Type: Article

References (4)

1. Andrutis, K. A., J. G. Fox, D. B. Schauer, R. P. Marini, J. C. Murphy, L. Yan, and J. V. Solnick. 1995. Inability of an isogenic urease-negative mutant strain of Helicobacter mustelae to colonize the ferret stomach. Infect. Immun. 63:3722-3725.
2. Bauerfeind, P., R. Garner, B. E. Dunn, and H. L. T. Mobley. 1997. Synthesis and activity of Helicobacter pylori urease and catalase at low pH. Gut 40:25-30.
3. Bauerfeind, P., R. M. Garner, and H. L. T. Mobley. 1996. Allelic exchange mutagenesis of nixA in Helicobacter pylori results in reduced nickel transport and urease activity. Infect. Immun. 64:2877-2880.
4. Blaser, M. J. 1992. Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation. Gastroenterology 102:720-727.