Gain in functions of mutant Cu,Zn-superoxide dismutases as a causative factor in familial amyotrophic lateral sclerosis: Less reactive oxidant formation but high spontaneous aggregation and precipitation

Free Radical Research

Volumn 33, Issue 1, 2000, Pages 65-73

  Okado Matsumoto, Ayako ^a   Myint, Theingi ^a   Fujii, Junichi ^b   Taniguchi, Naoyuki ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b YAMAGATA UNIVERSITY   (Japan)

Author keywords

Baculovirus; Copper toxicity; Gain of function; Hydroxyl radicals; Protein aggregation

Indexed keywords

COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; HYALIN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; REACTIVE OXYGEN METABOLITE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENZYME ACTIVITY; PATHOGENESIS; PROTEIN AGGREGATION; SITE DIRECTED MUTAGENESIS;

EID: 0034039381     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760000300621     Document Type: Article

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