Multistep phosphorelay proteins transmit oxidative stress signals to the fission yeast stress-activated protein kinase

Molecular Biology of the Cell

Volumn 11, Issue 4, 2000, Pages 1169-1181

  Nguyen, Aaron Ngocky ^a   Lee, Albert ^a   Place, Warren ^a   Shiozaki, Kazuhiro ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; ENZYME ACTIVATION; ENZYME ANALYSIS; GENE EXPRESSION; GENE INDUCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SIGNAL TRANSDUCTION; YEAST;

EUKARYOTA; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 0034036431     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.4.1169     Document Type: Article

References (52)

1. Alfa, C., Fantes, P., Hyams, J., McLeod, M., and Warbrick, E. (1993). Experiments with Fission Yeast: A Laboratory Course Manual, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
2. + gene as a new selectable marker for molecular genetic studies. Curr. Genet. 24, 491-495.
3. Banuett, F. (1998). Signaling in the yeasts: an informational cascade with links to the filamentous fungi. Microbiol. Mol. Biol. Rev. 62, 249-274.
4. Brewster, J.L., de Valoir, T., Dwyer, N.D., Winter, E., and Gustin, M.C. (1993). An osmosensing signal transduction pathway in yeast. Science 259, 1760-1763.
5. Cottarel, G. (1997). Mcs4, a two-component system response regulator homologue, regulates the Schizosaccharomyces pombe cell cycle control. Genetics 147, 1043-1051.
6. Degols, G., and Russell, P. (1997). Discrete roles of the Spc1 kinase and the Atf1 transcription factor in the UV response of Schizosaccharomyces pombe. Mol. Cell. Biol. 17, 3356-3363.
7. Degols, G., Shiozaki, K., and Russell, P. (1996). Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe. Mol. Cell. Biol. 16, 2870-2877.
8. Gupta, S., Campbell, D., Dérijard, B., and Davis, R.J. (1995). Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267, 389-393.
9. Higuchi, R., Krummel, B., and Saiki, R.K. (1988). A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res. 16, 7351-7367.
10. Ho, S.N., Hunt, H.D., Horton, R.M., Pullen, J.K., and Pease, L.R. (1989). Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 51-59.
11. Ip, Y.T., and Davis, R.J. (1998). Signal transduction by the c-Jun N-terminal kinase (JNK): from inflammation to development. Curr. Opin. Cell Biol. 10, 205-219.
12. + encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation. Genes Cells 1, 391-408.
13. Kato, T.J., Okazaki, K., Murakami, H., Stettler, S., Fantes, P.A., and Okayama, H. (1996). Stress signal, mediated by a Hog1-like MAP kinase, controls sexual development in fission yeast. FEBS Lett. 378, 207-212.
14. Kudo, N., Taoka, H., Toda, T., Yoshida, M., and Horinouchi, S. (1999). A novel nuclear export signal sensitive to oxidative stress in the fission yeast transcription factor Pap1. J. Biol. Chem. 274, 15151-15158.
15. Kyriakis, J.M., and Avruch, J. (1996). Sounding the alarm: protein kinase cascades activated by stress and inflammation. J. Biol. Chem. 271, 24313-24316.
16. Livingstone, C., Patel, G., and Jones, N. (1995). ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14, 1785-1797.
17. Loomis, W.F., Shaulsky, G., and Wang, N. (1997). Histidine kinases in signal transduction pathways of eukaryotes. J. Cell Sci. 110, 1141-1145.
18. Maeda, T., Takekawa, M., and Saito, H. (1995). Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 269, 554-558.
19. Maeda, T., Wurgler-Murphy, S.M., and Saito. H. (1994). A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369, 242-245.
20. Maundrell, K. (1990). nmt1 of fission yeast. J. Biol. Chem. 265, 10857-10864.
21. Millar, J.B.A., Buck, V., and Wilkinson, M.G. (1995). Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast. Genes Dev. 9, 2117-2130.
22. Mitchison, J.M. (1970). Physiological and cytological methods for Schizosaccharomyces pombe. Methods Cell Physiol. 4, 131-146.
23. Moradas-Ferreira, P., Costa, V., Piper, P., and Mager, W. (1996). The molecular defenses against reactive oxygen species in yeast. Mol. Microbiol. 19, 651-658.
24. Moreno, S., Klar, A., and Nurse, P. (1991). Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823.
25. Nakagawa, C.W., Mutoh, N., and Hayashi, Y. (1995). Transcriptional regulation of catalase gene in the fission yeast Schizosaccharomyces pombe: molecular cloning of the catalase gene and Northern blot analyses of the transcript. J. Biochem. 118, 109-116.
26. Nguyen, A.N., and Shiozaki, K. (1999). Heat shock-induced activation of stress MAP kinase is regulated by threonine- and tyrosine-specific phosphatases. Genes Dev. 13, 1653-1663.
27. +) that encodes a response regulator implicated in oxidative stress response. J. Biochem. 125, 1061-1066.
28. Ohmiya, R., Yamada, H., Nakashima, K., Aiba, H., and Mizuno, T. (1995). Osmoregulation of fission yeast: cloning of two distinct genes encoding glycerol-3-phosphate dehydrogenase, one of which is responsible for osmotolerance for growth. Mol. Microbiol. 18, 963-973.
29. Pidoux, A.L., Fawell, E.H., and Armstrong, J. (1990). Glyerol-3-phosphate dehydrogenase homologue from Schizosaccharomyces pombe. Nucleic Acids Res. 18, 7145.
30. Posas, F., and Saito, H. (1997). Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276, 1702-1705.
31. Posas, F., and Saito, H. (1998). Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J. 17, 1385-1394.
32. Posas, F., Takekawa, M., and Saito, H. (1998). Signal transduction by MAP kinase cascades in budding yeast. Curr. Opin. Microbiol. 1, 175-182.
33. Posas, F., Wurgler-Murphy, S.M., Maeda, T., Witten, E.A., Thai, T.C., and Saito, H. (1996). Yeast HOG1 MAP kinase cascade is regulated by a multiple phosphorelay mechanism in the SLN1-YPD1-SSK1 'two-component' osmosensor. Cell 86, 865-875.
34. Raingeaud, J., Whitmarsh, A.J., Barrett, T., Dérijard, B., and Davis, R.J. (1996). MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol. 16, 1247-1255.
35. Samejima, I., Mackie, S., and Fantes, P.A. (1997). Multiple modes of activation of the stress-responsive MAP kinase pathway in fission yeast. EMBO J. 16, 6162-6170.
36. + encodes a MAP kinase kinase kinase that phosphorylates and activates Wis1 MAP kinase kinase in response to high osmolarity. Mol. Biol. Cell 9, 2325-2335.
37. Schüller, C., Brewster, J.L., Alexander, M.R., Gustin, M.C., and Ruis, H. (1994). The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene. EMBO J. 13, 4382-4389.
38. Shieh, J.-C., Wilkinson, M.G., Buck, V., Morgan, B.A., Makino, K., and Millar, J.B.A. (1997). The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle. Genes Dev. 11, 1008-1022.
39. Shiozaki, K., and Russell, P. (1995). Cell-cycle control linked to the extracellular environment by MAP kinase pathway in fission yeast. Nature 378, 739-743.
40. Shiozaki, K., and Russell, P. (1996). Conjugation, meiosis and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast. Genes Dev. 10, 2276-2288.
41. Shiozaki, K., and Russell, P. (1997). Stress-activated protein kinase pathway in cell cycle control of fission yeast. Methods Enzymol. 283, 506-520.
42. Shiozaki, K., Shiozaki, M., and Russell, P. (1997). Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade. Mol. Biol. Cell 8, 409-419.
43. Shiozaki, K., Shiozaki, M., and Russell, P. (1998). Heat stress activates fission yeast Spc1/Sty1 MAPK by a MEKK-independent mechanism. Mol. Biol. Cell 9, 1339-1349.
44. + encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J. 14, 6193-6208.
45. Toda, T., Shimanuki, M., Saka, Y., Yamano, H., Adachi, Y., Shirakawa, M., Kyogoku, Y., and Yanagida, M. (1992). Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1. Mol. Cell. Biol. 12, 5474-5484.
46. Toda, T., Shimanuki, M., and Yanagida, M. (1991). Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases. Genes Dev. 5, 60-73.
47. Toone, W.M., Kuge, S., Samuels, M., Morgan, B.A., Toda, T., and Jones, N. (1998). Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev. 12, 1453-1463.
48. van Dam, H., Wilhelm, D., Herr, I., Steffen, A., Herrlich, P., and Angel, P. (1995). ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J. 14, 1798-1811.
49. Waskiewicz, A.J., and Cooper, J.A. (1995). Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr. Opin. Cell Biol. 7, 798-805.
50. Wilkinson, M.G., and Millar, J.B.A. (1998). SAPKs and transcription factors do the nucleocytoplasmic tango. Genes Dev. 12, 1391-1397.
51. Wilkinson, M.G., Samuels, M., Takeda, T., Toone, W.M., Shieh, J.-C., Toda, T., Millar, J.B.A., and Jones, N. (1996). The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast. Genes Dev. 10, 2289-2301.
52. Zhulin, I.B., Taylor, B.L., and Dixon, R. (1997). PAS domain S-boxes in archaea, bacteria and sensors for oxygen and redox. Trends Biochem. Sci. 22, 331-333.