Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade

Molecular Biology of the Cell

Volumn 8, Issue 3, 1997, Pages 409-419

  Shiozaki, Kazuhiro ^a   Shiozaki, Mitsue ^a   Russell, Paul ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTYROSINE; PROTEIN KINASE;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE; CELL CYCLE G2 PHASE; DNA FLANKING REGION; ENZYME PHOSPHORYLATION; EPISTASIS; GENE MUTATION; IMMUNOBLOTTING; MITOSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SCHIZOSACCHAROMYCES POMBE; SIGNAL TRANSDUCTION; STRESS; SUPPRESSOR GENE;

SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 0030968066     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.8.3.409     Document Type: Article

References (50)

1. Alfa, C., Fantes, P., Hyams, J., McLeod, M., and Warbrick, E. (1993). Experiments with Fission Yeast: A Laboratory Course Manual, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
2. Boguslawski, G. (1992). PBS2, a yeast gene encoding a putative protein kinase, interacts with the RAS2 pathway and affects osmotic sensitivity of Saccharomyces cerevisiae. J. Gen. Microbiol. 138, 2425-2432.
3. + protein kinase. EMBO J. 6, 3441-3447.
4. Brewster, J.L., de Valoir, T., Dwyer, N.D., Winter, E., and Gustin, M.C. (1993). An osmosensing signal transduction pathway in yeast. Science 259, 1760-1763.
5. Buck, V., Russell, P., and Millar, J.B. A. (1995). Identification of a cdk-activating kinase in fission yeast. EMBO J. 14, 6173-6183.
6. Cairns, B.R., Ramer, S.W., and Kornberg, R.D. (1992). Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase. Genes Dev. 6, 1305-1318.
7. Coleman, T.R., Tang, Z., and Dunphy, W.G. (1993). Negative regulation of the Wee1 protein kinase by direct action of the Nim1/Cdr1 mitotic inducer. Cell 72, 919-929.
8. Damagnez, V., Mäkelä, T.P., and Cottarel, G. (1995). Schizosaccharomyces pombe Mop1-Mcs2 is related to mammalian CAK. EMBO J. 14, 6164-6172.
9. Degols, G., Shiozaki, K., and Russell, P. (1996). Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe. Mol. Cell. Biol. 16, 2870-2877.
10. Dunphy, W.G. (1994). The decision to enter mitosis. Trends Cell Biol. 4, 202-207.
11. Fantes, P. (1979). Epistatic gene interactions in the control of division in fission yeast. Nature 279, 428-430.
12. Feilotter, H., Nurse, P., and Young, P. (1991). Genetic and molecular analysis of the cdr1/nim1 in Schizosaccharomyces pombe. Genetics 127, 309-318.
13. Grimm, C., Kohli, J., Murray, J., and Maundrell, K. (1988). Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement using the ura4 gene as a selectable marker. Mol. Gen. Genet. 215, 81-86.
14. Han, J., Lee, J.-D., Bibbs, L., and Ulevitch, R.J. (1994). A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265, 808-811.
15. Howe, L.R., Leevers, S.J., Gómez, N., Nakielny, S., Cohen, P., and Marshall, C.J. (1992). Activation of the MAP kinase pathway by the protein kinase raf. Cell 71, 335-342.
16. Kato, T.J., Okazaki, K., Murakami, H., Stettler, S., Fantes, P.A., and Okayama, H. (1996). Stress signal, mediated by a Hog1-like MAP kinase, controls sexual development in fission yeast. FEBS Lett. 378, 207-212.
17. Lee, J.C., Laydon, J.T., McDonnell, P.C., Gallagher, T.F., Kumar, S., Green, D., McNulty, D., Blumenthal, M.J., Heys, J.R., and Landvatter, S.W., Strickler, J.E., McLaughlin, M.M., Siemens, I.R., Fisher, S.M., Livi, G.P., White, J.R., Adams, J.L., and Young, P.R. (1994). A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372, 739-746.
18. Lee, K.S., and Levin, D.E. (1992). Dominant mutations in a gene encoding a putative protein kinase (BCK1) bypass the requirement of a Saccharomyces cerevisine protein kinase C homolog. Mol. Cell. Biol. 12, 172-182.
19. cdc2 on tyrosine-15. J. Biol. Chem. 269, 30530-30537.
20. Lundgren, K., Walworth, N., Booher, R., Dembski, M., Kirschner, M., and Beach, D. (1991). mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64, 1111-1122.
21. Maeda, T., Takekawa, M., and Saito, H. (1995). Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 269, 554-558.
22. Maeda, T., Wurgler-Murphy, S.M., and Saito, H. (1994). A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369, 242-245.
23. Maundrell, K. (1990). nmt1 of fission yeast. J. Biol. Chem. 265, 10857-10864.
24. Millar, J.B.A., Buck, V., and Wilkinson, M.G. (1995). Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast. Genes Dev. 9, 2117-2130.
25. Millar, J.B.A., Russell, P., Dixon, J.E., and Guan, K.L. (1992). Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast. EMBO J. 11, 4943-4952.
26. Mitchison, J.M. (1970). Physiological and cytological methods for Schizosaccharomyces pombe. Methods Cell Physiol. 4, 131-146.
27. Molz, L., and Beach, D. (1993). Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity. EMBO J. 12, 1723-1732.
28. Molz, L., Booher, R., Young, P., and Beach, D. (1989). cdc2 and the regulation of mitosis: six interacting mcs genes. Genetics 122, 773-82.
29. Moreno, S., Klar, A., and Nurse, P. (1991). Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194, 795-823.
30. Ogden, J.E., and Fantes, P.A. (1986). Isolation of a novel type of mutation in the mitotic control of Schizosaccharomyces pombe whose phenotypic expression is dependent on the genetic background and nutritional environment. Curr. Genet. 10, 509-514.
31. Ota, I.M., and Varshavsky, A. (1993). A yeast protein similar to bacterial two-component regulators. Science 262, 566-569.
32. Ottilie, S., Chernoff, J., Hannig, G., Hoffman, C.S., and Erikson, R.L. (1991). A fission yeast gene encoding a protein with features of protein tyrosine phosphatases. Proc. Natl. Acad. Sci. USA 88, 3455-3459.
33. + encode protein tyrosine phosphatases that negatively regulate mitosis. Mol. Cell. Biol. 12, 5571-5580.
34. Parker, L.L., Walter, S.A., Young, P.G., and Piwnica-Worms, H. (1993). Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase. Nature 363, 736-738.
35. Posas, F., Wurgler-Murphy, S.M., Maeda, M., Witten, E.A., Thai, T.C., and Saito, H. (1996). Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor. Cell 86, 865-875.
36. Rouse, J., Cohen, P., Trigon, S., Morange, M.A.-L., A., Zamanillo, D., Hunt, T., and Nebreda, A. (1994). A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78, 1027-1037.
37. + functions as an inducer in the mitotic control of fission yeast. Cell 45, 145-153.
38. + functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis. Cell 49, 569-576.
39. +, a gene encoding a protein kinase homolog. Cell 49, 559-567.
40. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual, Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
41. Schüller, C., Brewster, J.L., Alexander, M.R., Gustin, M.C., and Ruis, H. (1994). The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene. EMBO J. 13, 4382-4389.
42. Shiozaki, K., and Russell, P. (1995a). Cell-cycle control linked to the extracellular environment by MAP kinase pathway in fission yeast. Nature 378, 739-743.
43. Shiozaki, K., and Russell, P. (1995b). Multiple type 2C protein phosphatase genes functioning in fission yeast signal transduction cascades. Adv. Prot. Phosphatases 9, 249-262.
44. Shiozaki, K., and Russell, P. (1996). Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase via Atf1 transcription factor in fission yeast. Genes Dev. 10, 2276-2288.
45. + encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J. 14, 6193-6208.
46. Wang, Y., Xu, H.-P., Riggs, M., Rodgers, L., and Wigler, M. (1991). byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype. Mol. Cell. Biol. 11, 3554-3563.
47. Warbrick, E., and Fantes, P.A. (1991). The wis1 protein is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe. EMBO J. 10, 4291-4299.
48. Warbrick, E., and Fantes, P.A. (1992). Five novel elements involved in the regulation of mitosis in fission yeast. Mol. Gen. Genet. 232, 440-446.
49. Wilkinson, M.G., Samuels, M., Takeda, T., Toone, W.M., Shieh, J.-C., Toda, T., Millar, J.B. A., and Jones, N. (1996). The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast. Genes Dev. 18, 2289-2301.
50. Wu, L., and Russell, P. (1993). Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase. Nature 363, 738-741.