Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 5, 2000, Pages 1065-1073

  Highfield, Jackie A ^a   Mehta, Lina K ^a   Parrick, John ^a   Wardman, Peter ^b  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b MOUNT VERNON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN A2; BLEOMYCIN DERIVATIVE; HISTIDINE DERIVATIVE; HYDROXYL RADICAL; PRODRUG; PYRIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG ACTIVATION; DRUG CONJUGATION; DRUG DNA BINDING; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; HYPOXIA; NONHUMAN; PHYSICAL CHEMISTRY;

ANIMALS; BLEOMYCIN; CELL SURVIVAL; CRICETINAE; CRICETULUS; HYDROXYL RADICAL;

ANIMALIA;

EID: 0034035480     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00042-0     Document Type: Article

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