-
1
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. Ras oncogenes in human cancer: a review. Cancer Res. 1989;49:4682-4689.
-
(1989)
Cancer Res.
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
2
-
-
0021711728
-
Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins
-
Moelling K, Heimann B, Beimling P, Rapp UR, Sander T. Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins. Nature. 1984;312: 558-561.
-
(1984)
Nature
, vol.312
, pp. 558-561
-
-
Moelling, K.1
Heimann, B.2
Beimling, P.3
Rapp, U.R.4
Sander, T.5
-
4
-
-
0028903288
-
14-3-3 proteins on the MAP
-
Aitken A. 14-3-3 proteins on the MAP. Trends Biochem Sci. 1995;20:95-97.
-
(1995)
Trends Biochem Sci.
, vol.20
, pp. 95-97
-
-
Aitken, A.1
-
5
-
-
0029871708
-
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine
-
Muslin AJ, Tanner JW, Allen PM, Shaw AS. Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell. 1996;84:889-897.
-
(1996)
Cell
, vol.84
, pp. 889-897
-
-
Muslin, A.J.1
Tanner, J.W.2
Allen, P.M.3
Shaw, A.S.4
-
6
-
-
0030064432
-
Activated Ras displaces 14-3-3 from the amino terminus of c-Raf-1
-
Rommel C, Radziwill G, Lovric J, et al. Activated Ras displaces 14-3-3 from the amino terminus of c-Raf-1. Oncogene. 1996;12:609-619.
-
(1996)
Oncogene
, vol.12
, pp. 609-619
-
-
Rommel, C.1
Radziwill, G.2
Lovric, J.3
-
7
-
-
0030853961
-
Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo
-
Rommel C, Radziwill G, Moelling K, Hafen E. Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo. Mech Dev. 1997;64:95-105.
-
(1997)
Mech Dev.
, vol.64
, pp. 95-105
-
-
Rommel, C.1
Radziwill, G.2
Moelling, K.3
Hafen, E.4
-
8
-
-
0028175091
-
Raf meets Ras: Completing the framework of a signal transduction pathway
-
Avruch J, Zhang X, Kyriakis JM. Raf meets Ras: completing the framework of a signal transduction pathway Trends Biochem Sci. 1994;19:279-283.
-
(1994)
Trends Biochem Sci.
, vol.19
, pp. 279-283
-
-
Avruch, J.1
Zhang, X.2
Kyriakis, J.M.3
-
9
-
-
0029855237
-
Control of the ERK MAP kinase cascade by Ras and Raf
-
Marais R, Marshall CJ. Control of the ERK MAP kinase cascade by Ras and Raf. Cancer Surv. 1996;27:101-125.
-
(1996)
Cancer Surv.
, vol.27
, pp. 101-125
-
-
Marais, R.1
Marshall, C.J.2
-
10
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R, Krebs EG. The MAPK signaling cascade. FASEB J. 1995;9:726-735.
-
(1995)
FASEB J.
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
11
-
-
0030699253
-
MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src
-
Zimmermann S, Rommel C, Ziogas A, Lovric J, Moelling K, Radziwill G. MEK1 mediates a positive feedback on Raf-1 activity independently of Ras and Src. Oncogene. 1997;15:1503-1511.
-
(1997)
Oncogene
, vol.15
, pp. 1503-1511
-
-
Zimmermann, S.1
Rommel, C.2
Ziogas, A.3
Lovric, J.4
Moelling, K.5
Radziwill, G.6
-
12
-
-
0028950637
-
Insulin-stimulated disassociation of the SOS-Grb2 complex
-
Waters SB, Yamauchi K, Pessin JE. Insulin-stimulated disassociation of the SOS-Grb2 complex. Mol Cell Biol. 1995;15:2791-2799.
-
(1995)
Mol Cell Biol.
, vol.15
, pp. 2791-2799
-
-
Waters, S.B.1
Yamauchi, K.2
Pessin, J.E.3
-
14
-
-
0028237039
-
A biochemical function for ras-at last
-
Hall A. A biochemical function for ras-at last. Science. 1994;264:1413-1414.
-
(1994)
Science
, vol.264
, pp. 1413-1414
-
-
Hall, A.1
-
15
-
-
0028948382
-
Multiple Ras functions can contribute to mammalian cell transformation
-
White MA, Nicolette C, Minden A, et al. Multiple Ras functions can contribute to mammalian cell transformation. Cell 1995;80:533-541.
-
(1995)
Cell
, vol.80
, pp. 533-541
-
-
White, M.A.1
Nicolette, C.2
Minden, A.3
-
16
-
-
0029968827
-
Rho family GTPases: The cytoskeleton and beyond
-
Symsons M. Rho family GTPases: the cytoskeleton and beyond. Trends Biochem Sci. 1996;21:178-181.
-
(1996)
Trends Biochem Sci.
, vol.21
, pp. 178-181
-
-
Symsons, M.1
-
17
-
-
0028533575
-
Suppression of various human tumor cell lines by a dominant negative H-ras mutant
-
Ogiso Y, Sakai N, Watari H, Yokoyama T, Kuzumaki N. Suppression of various human tumor cell lines by a dominant negative H-ras mutant. Gene Ther. 1994;1:403-407.
-
(1994)
Gene Ther.
, vol.1
, pp. 403-407
-
-
Ogiso, Y.1
Sakai, N.2
Watari, H.3
Yokoyama, T.4
Kuzumaki, N.5
-
18
-
-
0026754369
-
Activation of the MAP kinase pathway by the protein kinase raf
-
Howe LR, Leevers SJ, Gomez N, Nakielny S, Cohen P, Marshall C. Activation of the MAP kinase pathway by the protein kinase raf. Cell. 1992;71:335-342.
-
(1992)
Cell
, vol.71
, pp. 335-342
-
-
Howe, L.R.1
Leevers, S.J.2
Gomez, N.3
Nakielny, S.4
Cohen, P.5
Marshall, C.6
-
19
-
-
0025979335
-
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
-
Kolch W, Heidecker G, Lloyd P, Rapp UR. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature. 1991;349:426-428.
-
(1991)
Nature
, vol.349
, pp. 426-428
-
-
Kolch, W.1
Heidecker, G.2
Lloyd, P.3
Rapp, U.R.4
-
20
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligonucleotide targeted against C-raf kinase
-
Monia BP, Johnston JF, Geiger T, Muller M, Fabbro D. Antitumor activity of a phosphorothioate antisense oligonucleotide targeted against C-raf kinase. Nat Med. 1996;2: 668-675.
-
(1996)
Nat Med.
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
21
-
-
0029150669
-
Inhibition of farneyl-transferase induces regression of mammary and salivary carcinomas in ras transgenic mice
-
Kohl NE, Omer CA, Conner MW. Inhibition of farneyl-transferase induces regression of mammary and salivary carcinomas in ras transgenic mice. Nat Med. 1995;1:792-797.
-
(1995)
Nat Med.
, vol.1
, pp. 792-797
-
-
Kohl, N.E.1
Omer, C.A.2
Conner, M.W.3
-
23
-
-
0031043776
-
Signal transduction from multiple Ras effectors
-
Katz ME, McCormick F. Signal transduction from multiple Ras effectors. Curr Opin Genet Dev. 1997;7:75-79.
-
(1997)
Curr Opin Genet Dev.
, vol.7
, pp. 75-79
-
-
Katz, M.E.1
McCormick, F.2
-
24
-
-
0032541613
-
Rho family proteins and Ras transformation: The RHOad less traveled gets congested
-
Zohn IM, Campbell SL, Khosravi-Far R, Rossman KL, Der CJ. Rho family proteins and Ras transformation: the RHOad less traveled gets congested. Oncogene. 1998;17: 1415-1438.
-
(1998)
Oncogene
, vol.17
, pp. 1415-1438
-
-
Zohn, I.M.1
Campbell, S.L.2
Khosravi-Far, R.3
Rossman, K.L.4
Der, C.J.5
-
25
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land H, Parada F, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 1983;304:596-602.
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, F.2
Weinberg, R.A.3
-
26
-
-
0030995824
-
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
-
Leone G, DeGregori J, Sears R, Jakol L, Nevins JR. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature. 1997;87:422-426.
-
(1997)
Nature
, vol.87
, pp. 422-426
-
-
Leone, G.1
DeGregori, J.2
Sears, R.3
Jakol, L.4
Nevins, J.R.5
-
27
-
-
0030950537
-
Cooperating oncogenes converge to regulate cyclin/cdk complexes
-
Lloyd AC, Obermuller F, Staddon S, Barth CF, McMahon M, Land H. Cooperating oncogenes converge to regulate cyclin/cdk complexes. Genes Dev. 1997;11:663-677.
-
(1997)
Genes Dev.
, vol.11
, pp. 663-677
-
-
Lloyd, A.C.1
Obermuller, F.2
Staddon, S.3
Barth, C.F.4
McMahon, M.5
Land, H.6
-
29
-
-
0026788001
-
Dominant negative MYC blocks transformation by ABL oncogenes
-
Sawyers CL, Callahan W, Witte ON. Dominant negative MYC blocks transformation by ABL oncogenes. Cell. 1992;70:901-910.
-
(1992)
Cell
, vol.70
, pp. 901-910
-
-
Sawyers, C.L.1
Callahan, W.2
Witte, O.N.3
-
30
-
-
0027236954
-
Production of high titer helper-free retroviruses by transient transfection
-
Pear WS, Nolan GP, Scott ML, Baltimore D. Production of high titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA. 1993;90:8392-8396.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8392-8396
-
-
Pear, W.S.1
Nolan, G.P.2
Scott, M.L.3
Baltimore, D.4
-
31
-
-
0023871422
-
A safe packaging line for gene transfer: Separating viral genes on two different plasmids
-
Markowitz D, Goff S, Bank A. A safe packaging line for gene transfer: separating viral genes on two different plasmids. J Virol. 1988;62:1120-1124.
-
(1988)
J Virol.
, vol.62
, pp. 1120-1124
-
-
Markowitz, D.1
Goff, S.2
Bank, A.3
-
32
-
-
0026262138
-
Short-term treatment with γ interferon induces stable reversion of ras-transformed mouse fibroblasts
-
Seliger B, Pfizenmaier K, Schaefer R. Short-term treatment with γ interferon induces stable reversion of ras-transformed mouse fibroblasts. J Virol. 1991;65:6307-6311.
-
(1991)
J Virol.
, vol.65
, pp. 6307-6311
-
-
Seliger, B.1
Pfizenmaier, K.2
Schaefer, R.3
-
33
-
-
0028295650
-
Cell cycle-dependent association of Gag-Mil and hsp90
-
Lovric J, Bischof O, Moelling K. Cell cycle-dependent association of Gag-Mil and hsp90. FEBS Lett. 1994;343: 15-21.
-
(1994)
FEBS Lett.
, vol.343
, pp. 15-21
-
-
Lovric, J.1
Bischof, O.2
Moelling, K.3
-
34
-
-
0029043888
-
A novel assay for apoptosis: Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein-labeled annexin V
-
Vermes I, Haanen C, Steffens NH, Reutelingsperger C. A novel assay for apoptosis: flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein-labeled annexin V. J Immunol Methods. 1995;184:39-51.
-
(1995)
J Immunol Methods
, vol.184
, pp. 39-51
-
-
Vermes, I.1
Haanen, C.2
Steffens, N.H.3
Reutelingsperger, C.4
-
35
-
-
1642639128
-
Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct
-
Georges RN, Mukhopadhyay T, Zhang Y, Yen N, Roth JA. Prevention of orthotopic human lung cancer growth by intratracheal instillation of a retroviral antisense K-ras construct. Science. 1993;260:85-88.
-
(1993)
Science
, vol.260
, pp. 85-88
-
-
Georges, R.N.1
Mukhopadhyay, T.2
Zhang, Y.3
Yen, N.4
Roth, J.A.5
-
36
-
-
0028903247
-
An essential role for Rac in Ras transformation
-
Qui RG, Chen J, Kirn D, McCormick F, Symons M. An essential role for Rac in Ras transformation. Nature. 1995;374:457-459.
-
(1995)
Nature
, vol.374
, pp. 457-459
-
-
Qui, R.G.1
Chen, J.2
Kirn, D.3
McCormick, F.4
Symons, M.5
-
37
-
-
0028800305
-
Activation of Rac1, RhoA, and mitogen-activated protein kinase is required for Ras transformation
-
Koshravi-Far R, Solski PA, Clark GJ, Kinch MS, Der C. Activation of Rac1, RhoA, and mitogen-activated protein kinase is required for Ras transformation. Mol Cell Biol. 1995;15:6443-6453.
-
(1995)
Mol Cell Biol.
, vol.15
, pp. 6443-6453
-
-
Koshravi-Far, R.1
Solski, P.A.2
Clark, G.J.3
Kinch, M.S.4
Der, C.5
-
38
-
-
0032541650
-
Increasing complexity of Ras signaling
-
Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ. Increasing complexity of Ras signaling. Oncogene. 1998;17:1395-1413.
-
(1998)
Oncogene
, vol.17
, pp. 1395-1413
-
-
Campbell, S.L.1
Khosravi-Far, R.2
Rossman, K.L.3
Clark, G.J.4
Der, C.J.5
-
39
-
-
0031659602
-
Ras: A versatile cellular switch
-
Rommel C, Hafen E. Ras: a versatile cellular switch. Curr Opin Genet Dev. 1998;8:412-418.
-
(1998)
Curr Opin Genet Dev.
, vol.8
, pp. 412-418
-
-
Rommel, C.1
Hafen, E.2
-
40
-
-
0029866641
-
Peptides containing a consensus Ras binding sequence from Raf-1 and the GTPase-activating protein NF1 inhibit Ras function
-
Clark GJ, Drugan JK, Terrell RS, et al. Peptides containing a consensus Ras binding sequence from Raf-1 and the GTPase-activating protein NF1 inhibit Ras function. Proc Natl Acad Sci USA. 1996;93:1577-1581.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 1577-1581
-
-
Clark, G.J.1
Drugan, J.K.2
Terrell, R.S.3
-
41
-
-
0029901805
-
Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells
-
Plattner R, Anderson MJ, Sato KY, Fasching CL, Der CJ, Stanbridge EJ. Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells. Proc Natl Acad Sci USA. 1996;93:6665-6670.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6665-6670
-
-
Plattner, R.1
Anderson, M.J.2
Sato, K.Y.3
Fasching, C.L.4
Der, C.J.5
Stanbridge, E.J.6
-
42
-
-
0028099742
-
Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant
-
Rapp UR, Troppmair J, Beck T, Birrer MJ. Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant. Oncogene. 1994;9:3493-3498.
-
(1994)
Oncogene
, vol.9
, pp. 3493-3498
-
-
Rapp, U.R.1
Troppmair, J.2
Beck, T.3
Birrer, M.J.4
-
43
-
-
0031041465
-
Characterization of downstream Ras signals that induce alternative protease-dependent invasive phenotypes
-
Silberman S, Janulis M, Schultz RM. Characterization of downstream Ras signals that induce alternative protease-dependent invasive phenotypes. J Biol Chem. 1997;272: 5927-5935.
-
(1997)
J Biol Chem.
, vol.272
, pp. 5927-5935
-
-
Silberman, S.1
Janulis, M.2
Schultz, R.M.3
-
44
-
-
0028879873
-
Myc but not Fos rescue of PDGF signaling block caused by kinase-inactive Src
-
Barone MV, Courtneidge SA. Myc but not Fos rescue of PDGF signaling block caused by kinase-inactive Src. Nature. 1995;378:509-512.
-
(1995)
Nature
, vol.378
, pp. 509-512
-
-
Barone, M.V.1
Courtneidge, S.A.2
|