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Volumn 41, Issue 2, 2000, Pages 117-129

Molecular mechanism of mechanical stress-induced cardiac hypertrophy

Author keywords

Angiotensin II; Cardiac hypertrophy; Integrin; Ion channel; Mechanical stress; Protein kinase

Indexed keywords

ANGIOTENSIN; ENDOTHELIN; INTEGRIN; ION CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE C; RAF PROTEIN;

EID: 0034027291     PISSN: 00214868     EISSN: None     Source Type: Journal    
DOI: 10.1536/jhj.41.117     Document Type: Review
Times cited : (24)

References (61)
  • 1
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study. N Engl J Med 1990; 322: 1561-6.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 2
    • 0024409475 scopus 로고
    • Load regulation of the properties of adult feline cardiocytes: Growth induction by cellular deformation
    • Mann DL, Kent RL, Cooper G. Load regulation of the properties of adult feline cardiocytes: growth induction by cellular deformation. Circ Res 1989: 64: 1079-90.
    • (1989) Circ Res , vol.64 , pp. 1079-1090
    • Mann, D.L.1    Kent, R.L.2    Cooper, G.3
  • 3
    • 0025217676 scopus 로고
    • Stretching cardiac myocytes stimulates proto-oncogene expression
    • Komuro I, Kaida T, Shibasaki Y, et al. Stretching cardiac myocytes stimulates proto-oncogene expression. J Biol Chem 1990; 265: 3595-8.
    • (1990) J Biol Chem , vol.265 , pp. 3595-3598
    • Komuro, I.1    Kaida, T.2    Shibasaki, Y.3
  • 4
    • 0026008492 scopus 로고
    • Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes
    • Komuro I, Katoh Y, Kaida T, et al. Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. J Biol Chem 1991; 266: 1265-8.
    • (1991) J Biol Chem , vol.266 , pp. 1265-1268
    • Komuro, I.1    Katoh, Y.2    Kaida, T.3
  • 5
    • 0027722248 scopus 로고
    • Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
    • Sadoshima J, Xu Y, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993; 95: 977-84.
    • (1993) Cell , vol.95 , pp. 977-984
    • Sadoshima, J.1    Xu, Y.2    Slayter, H.S.3    Izumo, S.4
  • 6
    • 0029117515 scopus 로고
    • Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy
    • Yamazaki T, Komuro I, Kudoh S, et al. Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy. Circ Res 1995; 77: 258-65.
    • (1995) Circ Res , vol.77 , pp. 258-265
    • Yamazaki, T.1    Komuro, I.2    Kudoh, S.3
  • 7
    • 13344287048 scopus 로고    scopus 로고
    • Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy
    • Yamazaki T, Komuro I, Kudoh S, et al. Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem 1996; 271: 3221-8.
    • (1996) J Biol Chem , vol.271 , pp. 3221-3228
    • Yamazaki, T.1    Komuro, I.2    Kudoh, S.3
  • 8
    • 0021399225 scopus 로고
    • Aortic perfusion pressure as a determinant of cardiac-protein synthesis
    • Kira Y, Kochel PJ, Gordon EE, Morgan HE. Aortic perfusion pressure as a determinant of cardiac-protein synthesis. Am J Physiol 1984; 246: C247-58.
    • (1984) Am J Physiol , vol.246
    • Kira, Y.1    Kochel, P.J.2    Gordon, E.E.3    Morgan, H.E.4
  • 9
    • 0027460744 scopus 로고
    • Control of cardiac gene expression by mechanical stress
    • Komuro I, Yazaki Y. Control of cardiac gene expression by mechanical stress. Annu Rev Physiol 1993; 55: 55-75.
    • (1993) Annu Rev Physiol , vol.55 , pp. 55-75
    • Komuro, I.1    Yazaki, Y.2
  • 10
    • 0030969371 scopus 로고    scopus 로고
    • The cellular and molecular response of cardiac myocytes to mechanical stress
    • Sadoshima J, Izumo S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu Rev Physiol 1997; 59: 551-71.
    • (1997) Annu Rev Physiol , vol.59 , pp. 551-571
    • Sadoshima, J.1    Izumo, S.2
  • 11
    • 0026069474 scopus 로고
    • Oncogenes and signal transduction
    • Cantley LC, Auger KR, Carpenter C, et al. Oncogenes and signal transduction. Cell 1991; 64: 281-302.
    • (1991) Cell , vol.64 , pp. 281-302
    • Cantley, L.C.1    Auger, K.R.2    Carpenter, C.3
  • 12
    • 0026056647 scopus 로고
    • Growth-regulated signal transduction by the MAP kinases and RSKs
    • Blenis J. Growth-regulated signal transduction by the MAP kinases and RSKs. Cancer Cells 1991; 3: 445-9.
    • (1991) Cancer Cells , vol.3 , pp. 445-449
    • Blenis, J.1
  • 13
    • 0027410497 scopus 로고
    • The MAP kinase cascade is essential for diverse signal transduction pathways
    • Nishida E, Gotoh Y. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem Sci. 1993; 18: 128-31.
    • (1993) Trends Biochem Sci. , vol.18 , pp. 128-131
    • Nishida, E.1    Gotoh, Y.2
  • 14
    • 0028133410 scopus 로고
    • Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal reorganization associated with cardiac muscle cell hypertrophy
    • Thorburn J, Frost JA, Thorburn J. Mitogen-activated protein kinases mediate changes in gene expression, but not cytoskeletal reorganization associated with cardiac muscle cell hypertrophy. J Cell Biol 1994; 126: 1565-72.
    • (1994) J Cell Biol , vol.126 , pp. 1565-1572
    • Thorburn, J.1    Frost, J.A.2    Thorburn, J.3
  • 15
    • 0029942783 scopus 로고    scopus 로고
    • Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes
    • Post GR, Goldstein D, Thuerauf DJ, Glembotski CC, Brown JH. Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes. J Biol Chem 1996; 271: 8452-7.
    • (1996) J Biol Chem , vol.271 , pp. 8452-8457
    • Post, G.R.1    Goldstein, D.2    Thuerauf, D.J.3    Glembotski, C.C.4    Brown, J.H.5
  • 16
    • 0029948892 scopus 로고    scopus 로고
    • Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes
    • Glennon PE, Kaddoura S, Sale EM, Sale GJ, Fuller SJ, Sugden PH. Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes. Cire Res 1996; 78: 954-61.
    • (1996) Cire Res , vol.78 , pp. 954-961
    • Glennon, P.E.1    Kaddoura, S.2    Sale, E.M.3    Sale, G.J.4    Fuller, S.J.5    Sugden, P.H.6
  • 17
    • 0027521065 scopus 로고
    • Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: Potential involvement of an autocrine / paracrine mechanism
    • Sadoshima J, Izumo S. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine / paracrine mechanism. EMBO J 1993; 12: 1681-92.
    • (1993) EMBO J , vol.12 , pp. 1681-1692
    • Sadoshima, J.1    Izumo, S.2
  • 18
    • 0027298699 scopus 로고
    • Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes
    • Yamazaki T, Tobe K, Hoh E, et al. Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes. J Biol Chem 1993; 268: 12069-76.
    • (1993) J Biol Chem , vol.268 , pp. 12069-12076
    • Yamazaki, T.1    Tobe, K.2    Hoh, E.3
  • 19
    • 0029090205 scopus 로고
    • Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes
    • Yamazaki T, Komuro I, Shiojima I, et al. Mechanical stress activates protein kinase cascade of phosphorylation in neonatal rat cardiac myocytes. J Clin Invest 1995; 96: 438-46.
    • (1995) J Clin Invest , vol.96 , pp. 438-446
    • Yamazaki, T.1    Komuro, I.2    Shiojima, I.3
  • 20
    • 0026647749 scopus 로고
    • Raf-1 activates MAP kinase-kinase
    • Kyriakis JM, App H, Zhang X, et al. Raf-1 activates MAP kinase-kinase. Nature 1992; 358: 417-21.
    • (1992) Nature , vol.358 , pp. 417-421
    • Kyriakis, J.M.1    App, H.2    Zhang, X.3
  • 21
    • 0033525546 scopus 로고    scopus 로고
    • Rho family small G proteins play critical roles in mechanical stress-induced hypertrophie responses in cardiac myocytes
    • Aikawa R, Komuro I, Yamazaki T, et al. Rho family small G proteins play critical roles in mechanical stress-induced hypertrophie responses in cardiac myocytes. Circ Res. 1999; 84: 458-66.
    • (1999) Circ Res. , vol.84 , pp. 458-466
    • Aikawa, R.1    Komuro, I.2    Yamazaki, T.3
  • 22
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-Jun N-terminal kinase (JNK)-from inflammation to development
    • Ip YT, Davis RJ. Signal transduction by the c-Jun N-terminal kinase (JNK)-from inflammation to development. Curr Opin Cell Biol 1998; 10: 205-19.
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 23
    • 0029914655 scopus 로고    scopus 로고
    • Mechanical stretch activates the stress-activated protein kinases in cardiac myocytes
    • Komuro I, Kudoh S, Yamazaki T, Zou Y, Shiojima I, Yazaki Y. Mechanical stretch activates the stress-activated protein kinases in cardiac myocytes. FASEB J 1996; 10: 631-6.
    • (1996) FASEB J , vol.10 , pp. 631-636
    • Komuro, I.1    Kudoh, S.2    Yamazaki, T.3    Zou, Y.4    Shiojima, I.5    Yazaki, Y.6
  • 24
    • 0031015356 scopus 로고    scopus 로고
    • Angiotensin II stimulates c-Jun NH2-terminal kinase in cultured cardiac myocytes of neonatal rats
    • Kudoh S, Komuro I, Mizuno T, et al. Angiotensin II stimulates c-Jun NH2-terminal kinase in cultured cardiac myocytes of neonatal rats. Circ Res 1997; 80: 139-46.
    • (1997) Circ Res , vol.80 , pp. 139-146
    • Kudoh, S.1    Komuro, I.2    Mizuno, T.3
  • 25
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK / JNK and p38 signaling pathways
    • Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK / JNK and p38 signaling pathways. Science 1997; 275: 90-4.
    • (1997) Science , vol.275 , pp. 90-94
    • Ichijo, H.1    Nishida, E.2    Irie, K.3
  • 26
    • 0032489550 scopus 로고    scopus 로고
    • Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells
    • Wang Y, Su B, Sah VP, Brown JH, Han J, Chien KR. Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells. J Biol Chem 1998; 273: 5423-6.
    • (1998) J Biol Chem , vol.273 , pp. 5423-5426
    • Wang, Y.1    Su, B.2    Sah, V.P.3    Brown, J.H.4    Han, J.5    Chien, K.R.6
  • 27
    • 0031844392 scopus 로고    scopus 로고
    • Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy
    • Nemoto S, Sheng Z, Lin A. Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy. Mol Cell Biol 1998; 18: 3518-26.
    • (1998) Mol Cell Biol , vol.18 , pp. 3518-3526
    • Nemoto, S.1    Sheng, Z.2    Lin, A.3
  • 28
    • 0031817208 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway and its biological function
    • New L, Han J. The p38 MAP kinase pathway and its biological function. Trends Cardiovasc Med 1998; 8: 220-8
    • (1998) Trends Cardiovasc Med , vol.8 , pp. 220-228
    • New, L.1    Han, J.2
  • 29
    • 0032515950 scopus 로고    scopus 로고
    • Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats
    • Bozkurt B, Kribbs SB, Clubb FJ, et al. Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats. Circulation 1998; 97: 1382-91.
    • (1998) Circulation , vol.97 , pp. 1382-1391
    • Bozkurt, B.1    Kribbs, S.B.2    Clubb, F.J.3
  • 30
    • 0032571270 scopus 로고    scopus 로고
    • Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases / c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses
    • Clerk A, Fuller SJ, Michael A, Sugden PH. Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases / c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses. J Biol Chem 1998; 273: 7228-34.
    • (1998) J Biol Chem , vol.273 , pp. 7228-7234
    • Clerk, A.1    Fuller, S.J.2    Michael, A.3    Sugden, P.H.4
  • 31
    • 0031939753 scopus 로고    scopus 로고
    • Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family
    • Wang Y, Huang S, Sah VP, et al. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J Biol Chem 1998; 273: 2161-8.
    • (1998) J Biol Chem , vol.273 , pp. 2161-2168
    • Wang, Y.1    Huang, S.2    Sah, V.P.3
  • 32
    • 0029982565 scopus 로고    scopus 로고
    • Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
    • Jiang Y, Chen C, Li Z, et al. Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J Biol Chem 1996; 271: 17920-6.
    • (1996) J Biol Chem , vol.271 , pp. 17920-17926
    • Jiang, Y.1    Chen, C.2    Li, Z.3
  • 33
    • 0025832626 scopus 로고
    • Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6
    • Erikson RL. Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6. J Biol Chem 1990; 266: 6007-10.
    • (1990) J Biol Chem , vol.266 , pp. 6007-6010
    • Erikson, R.L.1
  • 34
    • 0028847159 scopus 로고
    • Rapamycin selectively inhibits angiotensin II-induced increase in protein synthesis in cardiac myocytes in vitro. Potential role of 70-kD s6 kinase in angiotensin II-induced cardiac hypertrophy
    • Sadoshima J, Izumo S. Rapamycin selectively inhibits angiotensin II-induced increase in protein synthesis in cardiac myocytes in vitro. Potential role of 70-kD S6 kinase in angiotensin II-induced cardiac hypertrophy. Circ Res 1995; 77: 1040-52.
    • (1995) Circ Res , vol.77 , pp. 1040-1052
    • Sadoshima, J.1    Izumo, S.2
  • 35
    • 0343892188 scopus 로고
    • Molecular signals for initiating protein synthesis in organ hypertrophy
    • Hammond GL, Wieben E, Market CL. Molecular signals for initiating protein synthesis in organ hypertrophy. Proc Natl Acad Sci USA 1979; 76: 2455-9.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 2455-2459
    • Hammond, G.L.1    Wieben, E.2    Market, C.L.3
  • 36
    • 0026510060 scopus 로고
    • Cardiac actions of angiotensin II: Role of an intracardiac renin-angiotensin system
    • Baker KM, Booz GW, Dostal DE. Cardiac actions of angiotensin II: role of an intracardiac renin-angiotensin system. Annu Rev Physiol 1992; 54: 227-41.
    • (1992) Annu Rev Physiol , vol.54 , pp. 227-241
    • Baker, K.M.1    Booz, G.W.2    Dostal, D.E.3
  • 37
    • 0025688895 scopus 로고
    • Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation
    • Schnkert H, Dzau VJ, Tang SS, Hirsch AT, Apstein CS, Lorell BH. Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation. J Clin Invest 1990; 86: 1913-20.
    • (1990) J Clin Invest , vol.86 , pp. 1913-1920
    • Schnkert, H.1    Dzau, V.J.2    Tang, S.S.3    Hirsch, A.T.4    Apstein, C.S.5    Lorell, B.H.6
  • 38
    • 0024448370 scopus 로고
    • Converting enzyme inhibitor specifically prevents development and induces the regression of cardiac hypertrophy in rats
    • Linz W, Schoelkens BA, Ganten D. Converting enzyme inhibitor specifically prevents development and induces the regression of cardiac hypertrophy in rats. Clin Exp Hypertens. 1989; 11: 1325-50.
    • (1989) Clin Exp Hypertens , vol.11 , pp. 1325-1350
    • Linz, W.1    Schoelkens, B.A.2    Ganten, D.3
  • 39
    • 0025003064 scopus 로고
    • Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats
    • Baker KM, Cherin MI, Wixon SK, Aceto JF. Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats. Am J Physiol 1990; 259: H324-32
    • (1990) Am J Physiol , vol.259
    • Baker, K.M.1    Cherin, M.I.2    Wixon, S.K.3    Aceto, J.F.4
  • 40
    • 0027182438 scopus 로고
    • Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hypetplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype
    • Sadoshima J, Izumo S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hypetplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype. Circ Res 1993; 73: 413-23.
    • (1993) Circ Res , vol.73 , pp. 413-423
    • Sadoshima, J.1    Izumo, S.2
  • 41
    • 0001760220 scopus 로고
    • Angiotensin II induces hypertrophy and oncogene expression in cultured rat heart myocytes
    • abst.
    • Katoh Y, Komuro I, Shibasaki Y, Yamaguchi H, Yazaki Y. Angiotensin II induces hypertrophy and oncogene expression in cultured rat heart myocytes. Circulation 1989; 80: 11-450 [abst].
    • (1989) Circulation , vol.80 , pp. 11-450
    • Katoh, Y.1    Komuro, I.2    Shibasaki, Y.3    Yamaguchi, H.4    Yazaki, Y.5
  • 42
    • 0029670826 scopus 로고    scopus 로고
    • The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-sos pathway in cardiac myocytes
    • Sadoshima J, Izumo S. The heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J 1996; 15: 775-87.
    • (1996) EMBO J , vol.15 , pp. 775-787
    • Sadoshima, J.1    Izumo, S.2
  • 43
    • 0032559587 scopus 로고    scopus 로고
    • Cell type-specific angiotensin II-evoked signal transduction pathways: Critical roles of Gbetagamma subunit. Src family, and Ras in cardiac fibroblasts
    • Zou Y, Komuro I. Yamazaki T, et al. Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of Gbetagamma subunit. Src family, and Ras in cardiac fibroblasts. Circ Res 1998; 82: 337-45.
    • (1998) Circ Res , vol.82 , pp. 337-345
    • Zou, Y.1    Komuro, I.2    Yamazaki, T.3
  • 44
    • 0030449250 scopus 로고    scopus 로고
    • Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin Il-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes
    • Zou Y, Komuro I, Yamazaki T, et al. Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin Il-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes. J Biol Chem 1996; 271: 33592-7.
    • (1996) J Biol Chem , vol.271 , pp. 33592-33597
    • Zou, Y.1    Komuro, I.2    Yamazaki, T.3
  • 45
    • 0027257160 scopus 로고
    • Endothelin-1 is an autocrine / paracrine factor in the mechanism of angiotensin Il-induced hypertrophy in cultured rat cardiomyocytes
    • Ito H, Hirata Y, Adachi S, et al. Endothelin-1 is an autocrine / paracrine factor in the mechanism of angiotensin Il-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993; 92: 398-403.
    • (1993) J Clin Invest , vol.92 , pp. 398-403
    • Ito, H.1    Hirata, Y.2    Adachi, S.3
  • 46
    • 18244425296 scopus 로고    scopus 로고
    • Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: Evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes
    • Harada M, Itoh H, Nakagawa O, et al. Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes. Circulation 1997; 96: 3737-44.
    • (1997) Circulation , vol.96 , pp. 3737-3744
    • Harada, M.1    Itoh, H.2    Nakagawa, O.3
  • 47
    • 0029950405 scopus 로고    scopus 로고
    • Inhibition of myocardial endothelin pathway improves long-term survival in heart failure
    • Sakai S, Miyauchi T, Kobayashi M, Yamaguchi I, Goto K, Sugishita Y. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure. Nature 1996; 384: 353-5.
    • (1996) Nature , vol.384 , pp. 353-355
    • Sakai, S.1    Miyauchi, T.2    Kobayashi, M.3    Yamaguchi, I.4    Goto, K.5    Sugishita, Y.6
  • 48
    • 0032562289 scopus 로고    scopus 로고
    • Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy
    • Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science 1998; 280: 574-7.
    • (1998) Science , vol.280 , pp. 574-577
    • Akhter, S.A.1    Luttrell, L.M.2    Rockman, H.A.3    Iaccarino, G.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 49
    • 0025186789 scopus 로고
    • Mechanosensitive ion channels
    • Morris CE. Mechanosensitive ion channels. J Membra Biol 1990; 113: 93-107
    • (1990) J Membra Biol , vol.113 , pp. 93-107
    • Morris, C.E.1
  • 50
    • 0025827458 scopus 로고
    • Stretch-activated channels in heart cells: Relevance to cardiac hypertrophy
    • Bustamante JO, Ruknudin A, Sachs F. Stretch-activated channels in heart cells: relevance to cardiac hypertrophy. J Cardiovasc Pharmacol 1991; 17: S110-7.
    • (1991) J Cardiovasc Pharmacol , vol.17
    • Bustamante, J.O.1    Ruknudin, A.2    Sachs, F.3
  • 51
    • 0026753554 scopus 로고
    • Calcium imaging of mechanically induced fluxes in tissue-cultured chick heart: Role of stretch-activated ion channels
    • Sigurdson W, Ruknudin A, Sachs F. Calcium imaging of mechanically induced fluxes in tissue-cultured chick heart: role of stretch-activated ion channels. Am J Physiol 1992; 262: H1110-5.
    • (1992) Am J Physiol , vol.262
    • Sigurdson, W.1    Ruknudin, A.2    Sachs, F.3
  • 52
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin JD, Lu J-R, Antos CL, et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 1998; 93: 215-28.
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1    Lu, J.-R.2    Antos, C.L.3
  • 53
    • 0027459771 scopus 로고
    • Signal transduction from the extracellular matrix
    • Juliano RL, Haskill S. Signal transduction from the extracellular matrix. J Cell Biol 1993; 120: 577-85.
    • (1993) J Cell Biol , vol.120 , pp. 577-585
    • Juliano, R.L.1    Haskill, S.2
  • 54
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 55
    • 0029127658 scopus 로고
    • Stretching mesangial cells stimulates tyrosine phosphorylation of focal adhesion kinase pp125FAK
    • Hamasaki K, Mimura T, Furuya H. et al. Stretching mesangial cells stimulates tyrosine phosphorylation of focal adhesion kinase pp125FAK. Biochem Biophys Res Commun 1995; 212: 544-9.
    • (1995) Biochem Biophys Res Commun , vol.212 , pp. 544-549
    • Hamasaki, K.1    Mimura, T.2    Furuya, H.3
  • 57
    • 0030893060 scopus 로고    scopus 로고
    • MAP kinase-and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells
    • Thorburn J, Xu S, Thorburn A. MAP kinase-and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells. EMBO J 1997; 16: 1888-900.
    • (1997) EMBO J , vol.16 , pp. 1888-1900
    • Thorburn, J.1    Xu, S.2    Thorburn, A.3
  • 58
    • 0029658495 scopus 로고    scopus 로고
    • Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways
    • Sah VP, Hoshijima M, Chien KR, Brown JH. Rho is required for Galphaq and alpha1-adrenergic receptor signaling in cardiomyocytes. Dissociation of Ras and Rho pathways. J Biol Chem 1996; 271: 31185-90.
    • (1996) J Biol Chem , vol.271 , pp. 31185-31190
    • Sah, V.P.1    Hoshijima, M.2    Chien, K.R.3    Brown, J.H.4
  • 59
    • 0032489871 scopus 로고    scopus 로고
    • Angiotensin II activates RhoA in cardiac myocytes: A critical role of RhoA in angiotensin Il-induced premyofibril formation
    • Aoki H, Izumo S, Sadoshima J. Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin Il-induced premyofibril formation. Circ Res 1998; 82: 666-76.
    • (1998) Circ Res , vol.82 , pp. 666-676
    • Aoki, H.1    Izumo, S.2    Sadoshima, J.3
  • 61
    • 0025745212 scopus 로고
    • Insoluble fibronectin activates the Na / H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape
    • Schwartz MA, Lechene C, Ingber DE. Insoluble fibronectin activates the Na / H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proc Natl Acad Sci USA 1991; 88: 7849-53.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7849-7853
    • Schwartz, M.A.1    Lechene, C.2    Ingber, D.E.3


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