Metabolic-flux analysis of hybridoma cells under oxidative and reductive stress using mass balances

Cytotechnology

Volumn 32, Issue 2, 2000, Pages 97-107

  Bonarius, Hendrik P J ^a,d   Houtman, José H M ^a,c   Schmid, Georg ^a   De Gooijer, Cornelis D ^b   Tramper, Johannes ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c ZOETIS   (United States)

^d NOVO NORDISK A S   (Denmark)

Author keywords

Artificial electron acceptor; Dehydrogenases; Mammalian cell culture; Metabolic flux; Oxygen limitation

Indexed keywords

AMINO ACID SYNTHESIS; BIOREACTOR; CELL METABOLISM; CULTURE MEDIUM; HYBRIDOMA CELL CULTURE; METABOLIC FLUX; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDATION REDUCTION POTENTIAL; OXIDATION; OXYGEN CONCENTRATION; OXYGEN CONSUMPTION; PHENAZINE METHOSULFATE; PROLINE; REDUCTION; STEADY STATE;

EID: 0034026656     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008142218103     Document Type: Article

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