메뉴 건너뛰기




Volumn 12, Issue 3, 2000, Pages 921-934

Cell death is prevented in thalamic fields but not in injured neocortical areas after permanent focal ischaemia in mice overexpressing the anti-apoptotic protein Bcl-2

Author keywords

Apoptosis; Caspase; MCAO; Penumbra; Thalamus

Indexed keywords

MESSENGER RNA; PROTEIN BCL 2;

EID: 0034024798     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00984.x     Document Type: Article
Times cited : (46)

References (48)
  • 1
    • 0031030729 scopus 로고    scopus 로고
    • Expression of interleukin-1β converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery
    • Asahi, M., Hoshimaru, M., Uemura, Y., Tokime, T., Kojima, M., Ohtsuka, T., Matsuura, N., Aoki, T., Shibahara, K. & Kikuchi, H. (1997) Expression of interleukin-1β converting enzyme gene family and bcl-2 gene family in the rat brain following permanent occlusion of the middle cerebral artery. J. Cereb. Blood Flow Metab., 17, 11-18.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 11-18
    • Asahi, M.1    Hoshimaru, M.2    Uemura, Y.3    Tokime, T.4    Kojima, M.5    Ohtsuka, T.6    Matsuura, N.7    Aoki, T.8    Shibahara, K.9    Kikuchi, H.10
  • 2
    • 0032575694 scopus 로고    scopus 로고
    • Stroke-damaged neurons may commit cellular suicide
    • Barinaga, M. (1998) Stroke-damaged neurons may commit cellular suicide. Science, 281, 1302-1303.
    • (1998) Science , vol.281 , pp. 1302-1303
    • Barinaga, M.1
  • 3
    • 0023943431 scopus 로고
    • Thalamic infarcts: Clinical syndromes, etiology, and prognosis
    • Bogousslavsky, J., Regli, F. & Uske, A. (1988) Thalamic infarcts: clinical syndromes, etiology, and prognosis. Neurology, 38, 837-848.
    • (1988) Neurology , vol.38 , pp. 837-848
    • Bogousslavsky, J.1    Regli, F.2    Uske, A.3
  • 4
    • 0028798574 scopus 로고
    • Bcl-2 is expressed in neurons that survive focal ischemia in the rat
    • Chen, J., Graham, S.H., Chan, P.H., Lan, J., Zhou, R.L. & Simon, R.P. (1995) bcl-2 is expressed in neurons that survive focal ischemia in the rat. Neuroreport, 6, 394-398.
    • (1995) Neuroreport , vol.6 , pp. 394-398
    • Chen, J.1    Graham, S.H.2    Chan, P.H.3    Lan, J.4    Zhou, R.L.5    Simon, R.P.6
  • 5
    • 0030943111 scopus 로고    scopus 로고
    • Early detection of DNA strand breaks in the brain after transient focal ischemia: Implications for the role of DNA damage in apoptosis and neuronal cell death
    • Chen, J., Jin, K., Chen, M., Pei, W., Kawaguchi, K., Greenberg, D.A. & Simon, R.P. (1997) Early detection of DNA strand breaks in the brain after transient focal ischemia: implications for the role of DNA damage in apoptosis and neuronal cell death. J. Neurochem., 69, 232-245.
    • (1997) J. Neurochem. , vol.69 , pp. 232-245
    • Chen, J.1    Jin, K.2    Chen, M.3    Pei, W.4    Kawaguchi, K.5    Greenberg, D.A.6    Simon, R.P.7
  • 6
    • 0032124903 scopus 로고    scopus 로고
    • Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia
    • Chen, J., Nagayama, T., Jin, K., Stetler, R.A., Zhu, R.L., Graham, S.H. & Simon, R.P. (1998) Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci., 18, 4914-4928.
    • (1998) J. Neurosci. , vol.18 , pp. 4914-4928
    • Chen, J.1    Nagayama, T.2    Jin, K.3    Stetler, R.A.4    Zhu, R.L.5    Graham, S.H.6    Simon, R.P.7
  • 7
    • 0029962130 scopus 로고    scopus 로고
    • Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice
    • De Bilbao, F. & Dubois-Dauphin, M. (1996) Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice. Neuroscience, 71, 1111-1119.
    • (1996) Neuroscience , vol.71 , pp. 1111-1119
    • De Bilbao, F.1    Dubois-Dauphin, M.2
  • 8
    • 0033526922 scopus 로고    scopus 로고
    • Postnatal distribution of cpp 32 mRNA in the mouse central nervous system by in situ hybridization
    • De Bilbao, F., Guarin, E., Nef, P., Vallet, P., Giannakopoulos, P. & Dubois-Dauphin, M. (1999) Postnatal distribution of cpp 32 mRNA in the mouse central nervous system by in situ hybridization. J. Comp. Neurol., 409, 339-357.
    • (1999) J. Comp. Neurol. , vol.409 , pp. 339-357
    • De Bilbao, F.1    Guarin, E.2    Nef, P.3    Vallet, P.4    Giannakopoulos, P.5    Dubois-Dauphin, M.6
  • 9
    • 0030245811 scopus 로고    scopus 로고
    • Bax is required for neuronal death after trophic factor deprivation and during development
    • Deckwerth, T.L., Elliott, J.L., Knudson, C.M., Johnson, E.M., Snider, W.D. & Korsmeyer, S.J. (1996) Bax is required for neuronal death after trophic factor deprivation and during development. Neuron, 17, 401-411.
    • (1996) Neuron , vol.17 , pp. 401-411
    • Deckwerth, T.L.1    Elliott, J.L.2    Knudson, C.M.3    Johnson, E.M.4    Snider, W.D.5    Korsmeyer, S.J.6
  • 10
    • 0028343507 scopus 로고
    • Neonatal motoneurons overexpressing the Bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death
    • Dubois-Dauphin, M., Frankowski, H., Tsujimoto, Y., Huarte, J. & Martinou, J.C. (1994) Neonatal motoneurons overexpressing the Bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc. Natl Acad. Sci. USA, 91, 2459-2463.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 2459-2463
    • Dubois-Dauphin, M.1    Frankowski, H.2    Tsujimoto, Y.3    Huarte, J.4    Martinou, J.C.5
  • 12
    • 0025114156 scopus 로고
    • Progressive shrinkage of the thalamus following middle cerebral artery occlusion in rats
    • Fujie, W., Kirino, T., Tomukai, N., Iwasawa, T. & Tamura, A. (1990) Progressive shrinkage of the thalamus following middle cerebral artery occlusion in rats. Stroke, 21, 1485-1488.
    • (1990) Stroke , vol.21 , pp. 1485-1488
    • Fujie, W.1    Kirino, T.2    Tomukai, N.3    Iwasawa, T.4    Tamura, A.5
  • 13
    • 0029119364 scopus 로고
    • Bcl-2 protects murine erythroleukemia cells from p53-dependent and -independent radiation-induced cell death
    • Fukunaga-Johnson, N., Ryan, J.J., Wicha, M., Nunez, G. & Clarke, M.F. (1995) Bcl-2 protects murine erythroleukemia cells from p53-dependent and -independent radiation-induced cell death. Carcinogenesis, 16, 1761-1767.
    • (1995) Carcinogenesis , vol.16 , pp. 1761-1767
    • Fukunaga-Johnson, N.1    Ryan, J.J.2    Wicha, M.3    Nunez, G.4    Clarke, M.F.5
  • 14
    • 0000064578 scopus 로고    scopus 로고
    • Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats
    • Gillardon, F., Lenz, C., Waschke, K.F., Krajewski, S., Reed, J.C., Zimmermann, M. & Kuschinsky, W. (1996) Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats. Mol. Brain Res., 40, 254-260.
    • (1996) Mol. Brain Res. , vol.40 , pp. 254-260
    • Gillardon, F.1    Lenz, C.2    Waschke, K.F.3    Krajewski, S.4    Reed, J.C.5    Zimmermann, M.6    Kuschinsky, W.7
  • 15
    • 0024805137 scopus 로고
    • Rodent models of cerebral ischemia
    • Ginsberg, M.D. & Busto, R. (1989) Rodent models of cerebral ischemia. Stroke, 20, 1627-1642.
    • (1989) Stroke , vol.20 , pp. 1627-1642
    • Ginsberg, M.D.1    Busto, R.2
  • 16
    • 0027171640 scopus 로고
    • Chronological atrophy after transient middle cerebral artery occlusion in rats
    • Hara, H., Harada, K. & Sukamoto, T. (1993) Chronological atrophy after transient middle cerebral artery occlusion in rats. Brain Res., 618, 251-260.
    • (1993) Brain Res. , vol.618 , pp. 251-260
    • Hara, H.1    Harada, K.2    Sukamoto, T.3
  • 17
    • 0029879631 scopus 로고    scopus 로고
    • Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia
    • Hara, A., Iwai, T., Niwa, M., Uematsu, T., Yoshimi, N., Tanaka, T. & Mori, H. (1996) Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia. Brain Res., 711, 249-253.
    • (1996) Brain Res. , vol.711 , pp. 249-253
    • Hara, A.1    Iwai, T.2    Niwa, M.3    Uematsu, T.4    Yoshimi, N.5    Tanaka, T.6    Mori, H.7
  • 18
    • 0025335688 scopus 로고
    • Neural damage in the rat thalamus after cortical infarcts
    • Iizuka, H., Skatini, K. & Young, W. (1990) Neural damage in the rat thalamus after cortical infarcts. Stroke, 21, 790-794.
    • (1990) Stroke , vol.21 , pp. 790-794
    • Iizuka, H.1    Skatini, K.2    Young, W.3
  • 19
    • 0016662278 scopus 로고
    • Corticothalamic neurons and thalamocortical terminal fields: An investigation in rat using horseradish peroxidase and autoradiography
    • Jacobson, S. & Trojanowski, J.Q. (1975) Corticothalamic neurons and thalamocortical terminal fields: an investigation in rat using horseradish peroxidase and autoradiography. Brain Res., 85, 385-401.
    • (1975) Brain Res. , vol.85 , pp. 385-401
    • Jacobson, S.1    Trojanowski, J.Q.2
  • 21
    • 0030756459 scopus 로고    scopus 로고
    • Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic, V., Jackson-Lewis, V., de Bilbao, F., Dubois-Dauphin, M. & Przedborski, S. (1997) Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science, 277, 559-562.
    • (1997) Science , vol.277 , pp. 559-562
    • Kostic, V.1    Jackson-Lewis, V.2    De Bilbao, F.3    Dubois-Dauphin, M.4    Przedborski, S.5
  • 22
    • 0029956641 scopus 로고    scopus 로고
    • Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
    • Kuida, K., Zheng, T.S., Na, S., Kuan, C., Yang, D., Karasuyama, H., Rakic, P. & Flavell, R.A. (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature, 384, 368-372.
    • (1996) Nature , vol.384 , pp. 368-372
    • Kuida, K.1    Zheng, T.S.2    Na, S.3    Kuan, C.4    Yang, D.5    Karasuyama, H.6    Rakic, P.7    Flavell, R.A.8
  • 23
    • 0030025668 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo
    • Lawrence, M.S., Ho, D.Y., Sun, G.H., Steinberg, G.K. & Sapolsky, R.M. (1996) Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo. J. Neurosci., 16, 486-496.
    • (1996) J. Neurosci. , vol.16 , pp. 486-496
    • Lawrence, M.S.1    Ho, D.Y.2    Sun, G.H.3    Steinberg, G.K.4    Sapolsky, R.M.5
  • 24
    • 0027519254 scopus 로고
    • Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats
    • Lin, T.N., He, Y.Y., Wu, G., Khan, M. & Hsu, C.Y. (1993) Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats. Stroke, 24, 117-121.
    • (1993) Stroke , vol.24 , pp. 117-121
    • Lin, T.N.1    He, Y.Y.2    Wu, G.3    Khan, M.4    Hsu, C.Y.5
  • 27
    • 0028981908 scopus 로고
    • Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia
    • Linnik, M.D., Zahos, P., Geschwind, M.D. & Federoff, H.J. (1995a) Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke, 26, 1670-1674.
    • (1995) Stroke , vol.26 , pp. 1670-1674
    • Linnik, M.D.1    Zahos, P.2    Geschwind, M.D.3    Federoff, H.J.4
  • 28
    • 0032125488 scopus 로고    scopus 로고
    • Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis
    • Martin, L.J., Al-Abdulla, N.A., Brambrink, A.M., Kirsch, J.R., Sieber, F.E. & Portera-Cailliau, C. (1998) Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis. Brain Res. Bull., 46, 281-309.
    • (1998) Brain Res. Bull. , vol.46 , pp. 281-309
    • Martin, L.J.1    Al-Abdulla, N.A.2    Brambrink, A.M.3    Kirsch, J.R.4    Sieber, F.E.5    Portera-Cailliau, C.6
  • 30
    • 0026795049 scopus 로고
    • Middle cerebral artery occlusion in rats: A neurological and pathological evaluation of a reproducible model
    • Menzies, S.A., Hoff, J.T. & Betz, A.L. (1992) Middle cerebral artery occlusion in rats: a neurological and pathological evaluation of a reproducible model. Neurosurgery, 31, 100-107.
    • (1992) Neurosurgery , vol.31 , pp. 100-107
    • Menzies, S.A.1    Hoff, J.T.2    Betz, A.L.3
  • 31
    • 0031057656 scopus 로고    scopus 로고
    • BCL-2 gene family in the nervous system
    • Merry, D.E. & Korsmeyer, S.J. (1997) BCL-2 gene family in the nervous system. Annu. Rev. Neurosci., 20, 245-267.
    • (1997) Annu. Rev. Neurosci. , vol.20 , pp. 245-267
    • Merry, D.E.1    Korsmeyer, S.J.2
  • 33
    • 0030901498 scopus 로고    scopus 로고
    • Reperfusion following focal cerebral ischemia alters distribution of neuronal cells with DNA fragmentation in mice
    • Murakami, K., Kondo, T. & Chan, P.H. (1997) Reperfusion following focal cerebral ischemia alters distribution of neuronal cells with DNA fragmentation in mice. Brain Res., 751, 160-164.
    • (1997) Brain Res. , vol.751 , pp. 160-164
    • Murakami, K.1    Kondo, T.2    Chan, P.H.3
  • 35
    • 0029968643 scopus 로고    scopus 로고
    • Olfaction in birds: Differential embryonic expression of nine putative odorant receptors genes in the avian olfactory system
    • Nef, S., Allaman, I., Fiumelli, H., de Castro, E. & Nef, P. (1996) Olfaction in birds: differential embryonic expression of nine putative odorant receptors genes in the avian olfactory system. Mech. Dev., 55, 65-77.
    • (1996) Mech. Dev. , vol.55 , pp. 65-77
    • Nef, S.1    Allaman, I.2    Fiumelli, H.3    De Castro, E.4    Nef, P.5
  • 36
    • 0032520778 scopus 로고    scopus 로고
    • A physiologic role of Bcl-xl induced in activated macrophages
    • Okada, S., Zhang, H., Hatano, M. & Tokuhisa, T. (1998) A physiologic role of Bcl-xl induced in activated macrophages. J. Immunol., 160, 2590-2596.
    • (1998) J. Immunol. , vol.160 , pp. 2590-2596
    • Okada, S.1    Zhang, H.2    Hatano, M.3    Tokuhisa, T.4
  • 38
    • 0023790233 scopus 로고
    • Ischemic cortical lesions after permanent occlusion of individual middle cerebral artery branches in rats
    • Rubino, G.J. & Young, W. (1988) Ischemic cortical lesions after permanent occlusion of individual middle cerebral artery branches in rats. Stroke, 19, 870-877.
    • (1988) Stroke , vol.19 , pp. 870-877
    • Rubino, G.J.1    Young, W.2
  • 39
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen, G.S. & Dixit, V.M. (1997) Caspases: intracellular signaling by proteolysis. Cell, 91, 443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 40
    • 0027963452 scopus 로고
    • Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus
    • Shimazaki, K., Ishida, A. & Kawai, N. (1994) Increase in bcl-2 oncoprotein and the tolerance to ischemia-induced neuronal death in the gerbil hippocampus. Neurosci. Res., 20, 95-99.
    • (1994) Neurosci. Res. , vol.20 , pp. 95-99
    • Shimazaki, K.1    Ishida, A.2    Kawai, N.3
  • 41
    • 0029891535 scopus 로고    scopus 로고
    • Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: Possible involvement of common mediators in apoptotic and necrotic signal transduction
    • Shimizu, S., Eguchi, Y., Kamiike, W., Waguri, S., Uchiyama, Y., Matsuda, H. & Tsujimoto, Y. (1996) Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transduction. Oncogene, 12, 2045-2050.
    • (1996) Oncogene , vol.12 , pp. 2045-2050
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Waguri, S.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimoto, Y.7
  • 42
    • 0029918952 scopus 로고    scopus 로고
    • Apoptosis and c-Jun in the thalamus of the rat following cortical infarction
    • Soriano, M.A., Ferrer, I., Rodriguez-Farré, E. & Planas, A.M. (1996) Apoptosis and c-Jun in the thalamus of the rat following cortical infarction. Neuroreport, 7, 425-428.
    • (1996) Neuroreport , vol.7 , pp. 425-428
    • Soriano, M.A.1    Ferrer, I.2    Rodriguez-Farré, E.3    Planas, A.M.4
  • 43
    • 0029952943 scopus 로고    scopus 로고
    • DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions
    • States, B.A., Honkaniemi, J., Weinstein, P.R. & Sharp, F.R. (1996) DNA fragmentation and HSP70 protein induction in hippocampus and cortex occurs in separate neurons following permanent middle cerebral artery occlusions. J. Cereb. Blood Flow Metab., 16, 1165-1175.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 1165-1175
    • States, B.A.1    Honkaniemi, J.2    Weinstein, P.R.3    Sharp, F.R.4
  • 44
    • 0025838155 scopus 로고
    • Thalamic atrophy following cerebral infarction in the territory of the middle cerebral artery
    • Tamura, A., Tahira, Y., Nagashima, H., Kirino, T., Gotoh, O., Hojo, S. & Sano, K. (1991) Thalamic atrophy following cerebral infarction in the territory of the middle cerebral artery. Stroke, 22, 615-618.
    • (1991) Stroke , vol.22 , pp. 615-618
    • Tamura, A.1    Tahira, Y.2    Nagashima, H.3    Kirino, T.4    Gotoh, O.5    Hojo, S.6    Sano, K.7
  • 45
    • 0032520195 scopus 로고    scopus 로고
    • Widespread elimination of naturally occurring neuronal death in bax-deficient mice
    • White, F.A., Keller-Peck, C.R., Knudson, C.M., Korsmeyer, S.J. & Snider, W.D. (1998) Widespread elimination of naturally occurring neuronal death in bax-deficient mice. J. Neurosci., 18, 1428-1439.
    • (1998) J. Neurosci. , vol.18 , pp. 1428-1439
    • White, F.A.1    Keller-Peck, C.R.2    Knudson, C.M.3    Korsmeyer, S.J.4    Snider, W.D.5
  • 48
    • 0003197018 scopus 로고
    • Vascular disease of the central nervous system
    • Blackwood, W. & Corsellis, J.A.N. (eds). Edward Arnold, London, UK
    • Yates, P.O. (1976) Vascular disease of the central nervous system. In Blackwood, W. & Corsellis, J.A.N. (eds), Greenfield's Neuropathology, 3rd edn. Edward Arnold, London, UK, pp. 86-147.
    • (1976) Greenfield's Neuropathology, 3rd Edn. , pp. 86-147
    • Yates, P.O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.