Inhibition of vascular contraction by intracisternal administration of preproendothelin-1 mRNA antisense oligoDNA in a rat experimental vasospasm model

Journal of Neurosurgery

Volumn 85, Issue 5, 1996, Pages 846-852

  Onoda, Keisuke ^a   Ono, Shigeki ^a   Ogihara, Kotaro ^a   Shiota, Tomomi ^a   Asari, Shoji ^a   Ohmoto, Takashi ^a   Ninomiya, Yoshifumi ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

antisense oligoDNA; gene therapy; preproendothelin 1 mRNA; rat; subarachnoid hemorrhage; vasospasm

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; ENDOTHELIN 1; PROTEIN PRECURSOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BASILAR ARTERY; GENE TECHNOLOGY; MESSENGER RNA SYNTHESIS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SUBARACHNOID HEMORRHAGE; VASOCONSTRICTION; VASOSPASM;

EID: 0029827005     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1996.85.5.0846     Document Type: Article

References (33)

1. Abe J, Zhou W, Taguchi J, et al: Suppression of neointimal smooth muscle cell accumulation in vivo by antisense CDC2 and CDK2 oligonucleotides in rat carotid artery. Biochem Biophys Res Commun 198:16-24, 1994
2. Aoki T, Takenaka K, Suzuki S, et al: The role of hemolysate in the facilitation of oxyhemoglobin-induced contraction in rabbit basilar arteries. J Neurosurg 81:261-266, 1994
3. Barry KJ, Gogjian MA, Stein BM: Small animal model for investigation of subarachnoid hemorrhage and cerebral vasospasm. Stroke 10:538-541, 1979
4. Bennett MR, Anglin S, McEwan JR, et al: Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc antisense oligodeoxynucleotides, J Clin Invest 93:820-828, 1991
5. Clozel M, Watanabe H: BQ-123, a peptidic endothelin ETA receptor antagonist, prevents the early cerebral vasospasm following subarachnoid hemorrhage after intracisternal but not intravenous injection. Life Sci 52:825-834, 1993
6. Cocks TM, Malta E, King SJ, et al: Oxyhaemoglobin increases the production of endothelin-1 by endthelial cells in culture. Eur J Pharmacol 196:177-182, 1991
7. Delgado-Zygmunt TJ, Arbab MAR, Shiokawa Y, et al: A primate model for acute and late cerebral vasospasm: angiographie findings. Acta Neurochir 118:130-136, 1992
8. Edelman ER, Simons M, Sirois MG, et al: c-myc in vasculoproliferative disease. Circ Res 76:176-182, 1995
9. Endo S, Branson PJ, Alksne JF: Experimental model of symptomatic vasospasm in rabbits. Stroke 19:1420-1425, 1988
10. International Committee for Standardization in Haematology of the European Society for Haematology. Recommendations and requirements for haemoglobinometry in human blood. J Clin Pathol 18:353-355, 1965
11. Kamiya K, Kuyama H, Symon L: An experimental study of the acute stage of subarachnoid hemorrhage. J Neurosurg 59: 917-924, 1983
12. Kobayashi M, Nishikibe M, Maruyama H, et al: Localization and alteration of immunoreactive endothelin-1 in canine basilar arteries following subarachnoid hemorrhage. Acta Histochem Cytochem 28:129-136, 1995
13. Kubota T, Handa Y, Tsuchida A, et al: The kinetics of lymphocyte subsets and macrophages in subarachnoid space after subarachnoid hemorrhage in rats. Stroke 24:1993-2001, 1993
14. Kurihara Y, Kurihara H, Suzuki H, et al: Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 368:703-710, 1994
15. Lim CS, Chapman GD, Gammon RS, et al: Direct in vivo gene transfer into the coronary and peripheral vasculatures of the infant dog. Circulation 83:2007-2011, 1990
16. Maniatis T, Fritsch EF, Sambrook J: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1982
17. Mayberg MR, Okada T, Bark DH: The role of hemoglobin in arterial narrowing after subarachnoid hemorrhage. J Neurosurg 72:634-640, 1990
18. Morishita R, Gibbons GH, Ellison KE, et al: Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides. J Clin Invest 93:1458-1464, 1994
19. Morishita R, Gibbons GH, Ellison KE, et al: Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia. Proc Natl Acad Sci USA 90: 8474-8478, 1993
20. Mosmann T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Method 65:55-63, 1983
21. Nabel EG, Plautz G, Nabel GJ: Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 249:1285-1288, 1990
22. Ohlstein EH, Storer BL: Oxyhemoglobin stimulation of endothelin production in cultured endothelial cells. J Neurosurg 77:274-278, 1992
23. Ohno T, Gordon D, San H, et al: Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 265:781-784, 1994
24. Onoue H, Nakamura N, Toda N: Prolonged exposure to oxyhemoglobin modifies the response of isolated dog middle cerebral arteries to vasoactive substances. Stroke 20:657-663, 1989
25. Sakurai T, Yanagisawa M, Inoue A, et al: cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA. Biochem Biophys Res Commun 175:44-47, 1991
26. Simons M, Edelman ER, DeKeyser JL, et al: Antisense c-myb oligonucleotides inhibit intimai arterial smooth muscle cell accumulation in vivo. Nature 359:67-70, 1992
27. Toda N, Kawakami M, Kodama N: Prevention by nicardipine of dog basilar artery spasm caused by oxyhemoglobin in vivo and in vitro. Eur J Pharmacol 195:175-177, 1991
28. Uchida S, Takemoto F, Ogata E, et al: Detection of endothelin-1 mRNA by RT-PCR in isolated rat renal tubules. Biochem Biophys Res Commun 188:108-113, 1992
29. von der Leyen HE, Gibbons GH, Morishita R, et al: Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl Acad Sci USA 92:1137-1141, 1995
30. Wagner RW: Gene inhibition using antisense oligodeoxynucleotides. Nature 372:333-335, 1994
31. Whitesell L, Geselowitz D, Chavany C, et al: Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: implications for therapeutic application within the central nervous system. Proc Natl Acad Sci USA 90:4665-4669, 1993
32. Yamaura I, Tani E, Maeda Y, et al: Endothelin-1 of canine basilar artery in vasospasm. J Neurosurg 76:99-105, 1992
33. Yanagisawa M, Kurihara H, Kimura S: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415, 1988