Vascular biology of endothelin

Journal of Cardiovascular Pharmacology

Volumn 32, Issue SUPPL. 3, 1998, Pages

  Schiffrin, Ernesto L ^a   Touyz, Rhian M ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

Endothelin converting enzyme; Endothelium; ET(A) and ET(B) receptors; Intracellular signaling; Preproendothelin 1; Vascular smooth muscle cells

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN CONVERTING ENZYME; PHOSPHOLIPASE A2; PHOSPHOLIPASE D; PROTEIN KINASE C;

ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CONFERENCE PAPER; ENZYME ACTIVATION; HEART FAILURE; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SECOND MESSENGER; SIGNAL TRANSDUCTION;

EID: 0032418963     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (25)

1. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:411-5.
2. Hahn AWA, Resink TJ, Scott-Burden T, Powell J, Dohi Y, Bühler FR. Stimulation of endothelin mRNA and secretion in rat vascular smooth muscle cells: a novel autocrine function. Cell Regul 1990;1:649-59.
3. Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T. The human endothelin family-3 structurally and pharmacologically distinct isopeptides predicted by 3 separate genes. Proc Natl Acad Sci USA 1989;86:2863-7.
4. Arai H, Hori S, Aramori I, Ohkuba H, Nakanishi S. Cloning and expression of a cDNA encoding an endothelin receptor. Nature 1990;348:730-2.
5. Sakurai T, Yanagisawa M, Takuwa H, Kimura S, Goto K, Masaki T. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 1990;348:732-5.
6. Kurihara Y, Kurihara H, Suzuki H, et al. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 1994;368:703-10.
7. Baynash A, Hosoda K, Giaid A, et al. Interaction of endothelin-3 with endothelin-B receptors is essential for development of epidermal melanocytes and enteric neurons. Cell 1994;79:1277-85.
8. Hosoda K, Hammer R, Richardson J, et al. Targeted and natural (Piebald-Lethal) mutation of endothelin-B receptor gene produces megacolon associated with spotted coat color in mice. Cell 1994;79:1267-76.
9. Puffenberger EG, Hosoda K, Washington SS, et al. A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung disease. Cell 1994;79:1257-66.
10. Schiffrin EL. Endothelin: potential role in hypertension and vascular hypertrophy. Brief review. Hypertension 1995;25:1135-43.
11. Schiffrin EL, Intengan HD, Thibault G, Touyz RM. Clinical significance of endothelin in cardiovascular disease. Curr Opin Cardial 1997;12:354-67.
12. Russell FD, Skepper JN, Davenport AP. Detection of endothelin receptors in human coronary artery vascular smooth muscle cells but not endothelial cells by using electron microscope autoradiography. J Cardiovasc Pharmacol 1997;29:820-6.
13. Haynes WG, Ferro CJ, O'Kane KPJ, Somerville D, Lomax CC, Webb DJ. Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in humans. Circulation 1996;93:1860-70.
14. Ito H, Hirata Y, Adachi S, et al. Endothelin-1 is an autocrine/ paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993;92: 398-403.
15. Larivière R, Deng LY, Day R, Sventek P, Thibault G, Schiffrin EL. Increased endothelin-1 gene expression in the endothelium of coronary arteries and endocardium in the DOCA-salt hypertensive rat. J Mol Cell Cardiol 1995;27:2123-31.
16. Yamazaki T, Komuro I, Kudoh S, et al. Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem 1996;271:3221-8.
17. Ito H, Adachi S, Tamamori M, et al. Mild hypoxia induces hypertrophy of cultured neonatal rat cardiomyocytes: a possible endogenous endothelin-1-mediated mechanism. J Mol Cell Cardiol 1996;28:1271-7.
18. Katwa LC, Guarda E, Weber KT. Endothelin receptors in cultured adult rat cardiac fibroblasts. Cardiovasc Res 1993;27: 2125-9.
19. Fareh J, Touyz RM, Schiffrin EL, Thibault G. Endothelin-1 and angiotensin II receptors in cells from rat hypertrophied heart. Receptor regulation and intracellular Ca2+ modulation. Circ Res 1996;78:302-11.
20. Shubeita HE, McDonough PM, Harris AN, et al. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. J Biol Chem 1990; 265:20555-62.
21. Bogoyevitch MA, Glennon PE, Andersson MB, et al. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy. J Biol Chem 1994; 269:1110-9.
22. Lee ME, Temizer D, Clifford J, Quertermous T. Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells. J Biol Chem 1991;266:16188-92.
23. Kawana M, Lee ME, Quertermous EE, Quertermous T. Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene. Mol Cell Biol 1995;15:4225-31.
24. 2 inhibit ET-1 secretion from endothelial cells by stimulating particulate guanylate cyclase. Am J Physiol 1996;270:H1342-9.
25. Malek AM, Lee IW, Alper SL, Izumo S. Regulation of endothelin-1 gene expression by cell shape and the microfilament network in vascular endothelium. Am J Physiol 1997;273:C1764-74.