Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide

British Journal of Pharmacology

Volumn 130, Issue 2, 2000, Pages 478-484

  McClenaghan, Neville H ^a   Ball, Andrew J ^a   Flatt, Peter R ^a  

^a UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

BTS 67 582; Clonal pancreatic beta cells; Desensitization; Insulin release; Tolbutamide

Indexed keywords

1,1 DIMETHYL 2 (2 MORPHOLINOPHENYL)GUANIDINE FUMARATE; 2 OXOISOCAPROIC ACID; ALANINE; ANTIDIABETIC AGENT; ARGININE; EFAROXAN; FORSKOLIN; GLUCOSE; INSULIN; PHORBOL 12 ACETATE 13 MYRISTATE; POTASSIUM CHLORIDE; TOLBUTAMIDE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DESENSITIZATION; DRUG MECHANISM; INSULIN LIKE ACTIVITY; INSULIN RELEASE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 0034017796     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703306     Document Type: Article

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