Evaluation of BTS 67 582, a novel antidiabetic agent, in normal and diabetic rats

British Journal of Pharmacology

Volumn 120, Issue 6, 1997, Pages 1135-1143

  Jones, R B ^a   Dickinson, K ^a   Anthony, D M ^a   Marita, A R ^b   Kaul, C L ^b   Buckett, W R ^a  

^a ABBOTT LABORATORIES   (United States)

^b Knoll Pharmaceuticals   (India)

Author keywords

BTS 67 582; Plasma glucose; Plasma insulin; Streptozotocin induced diabetes

Indexed keywords

1,1 DIMETHYL 2 (2 MORPHOLINOPHENYL)GUANIDINE FUMARATE; ANTIDIABETIC AGENT; CROMAKALIM; DIAZOXIDE; GLIBENCLAMIDE; GLUCOSE; INSULIN; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA STRIP; ARTERY DILATATION; ARTICLE; BRAIN; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG RECEPTOR BINDING; DRUG SCREENING; GLUCOSE BLOOD LEVEL; GUINEA PIG; HEART VENTRICLE; INSULIN BLOOD LEVEL; INSULINOMA; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

ANIMALS; AORTA, THORACIC; BENZOPYRANS; BLOOD GLUCOSE; BRAIN; CROMAKALIM; DIABETES MELLITUS, EXPERIMENTAL; DIAZOXIDE; GLUCOSE; GLYBURIDE; GUANIDINES; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNEL BLOCKERS; PYRROLES; RATS; RATS, WISTAR; TUMOR CELLS, CULTURED;

EID: 0031002135     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701019     Document Type: Article

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