-
1
-
-
0029943449
-
Mismatch repair in replication fidelity, genetic recombination and cancer biology
-
Modrich, P. and Lahue, R. (1996) Mismatch repair in replication fidelity, genetic recombination and cancer biology. Annu. Rev. Biochem., 65, 101-133.
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 101-133
-
-
Modrich, P.1
Lahue, R.2
-
2
-
-
0027248156
-
Genetics, natural history, tumor spectrum and pathology of hereditary nonpolyposis colorectal cancer: An updated review
-
Lynch, H., Smyrk, T. and Watson, P. (1993) Genetics, natural history, tumor spectrum and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology, 104, 1535-1549.
-
(1993)
Gastroenterology
, vol.104
, pp. 1535-1549
-
-
Lynch, H.1
Smyrk, T.2
Watson, P.3
-
3
-
-
0029833872
-
Hereditary nonpolyposis colorectal cancer (Lynch syndrome): An updated review
-
Lynch, H.T. and Smyrk, T.C. (1996) Hereditary nonpolyposis colorectal cancer (Lynch syndrome): an updated review. Cancer, 78, 1149-1167.
-
(1996)
Cancer
, vol.78
, pp. 1149-1167
-
-
Lynch, H.T.1
Smyrk, T.C.2
-
4
-
-
0342533723
-
Loss or somatic mutations of hMSH2 occur in hereditary nonpolyposis colorectal cancers with hMSH2 germline mutations
-
Lu, S.L., Akiyama, Y., Nagasaki, H., Nomizu, T., Ikeda, E., Baba, S., Ushio, K., Iwama, T., Maruyama, K. and Yuasa, Y. (1996) Loss or somatic mutations of hMSH2 occur in hereditary nonpolyposis colorectal cancers with hMSH2 germline mutations. Jpn. J. Cancer Res., 87, 279-287.
-
(1996)
Jpn. J. Cancer Res.
, vol.87
, pp. 279-287
-
-
Lu, S.L.1
Akiyama, Y.2
Nagasaki, H.3
Nomizu, T.4
Ikeda, E.5
Baba, S.6
Ushio, K.7
Iwama, T.8
Maruyama, K.9
Yuasa, Y.10
-
5
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
Herman, J.G., Umar, A., Polyak, K., Graff, J.R., Ahiya, N., Issa, J.P.J., Markowitz, S., Willson, J.K.V., Hamilton, S.R., Kinzler, K.W., Kane, M.F., Kolodner, R.D., Vogelstein, B., Kunkel, T.A. and Baylin, S.B. (1998) Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl Acad. Sci. USA, 95, 6870-6875.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahiya, N.5
Issa, J.P.J.6
Markowitz, S.7
Willson, J.K.V.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
6
-
-
0032146118
-
Hypermethylation of the hMLH1 promotor in colon cancer with microsatellite instability
-
Cunningham, J.M., Christensen, E.R., Tester, D.J., Kim, C.Y., Roche, P.C., Burgart, L.J. and Thibodeau, S.N. (1998) Hypermethylation of the hMLH1 promotor in colon cancer with microsatellite instability. Cancer Res., 58, 3455-3460.
-
(1998)
Cancer Res.
, vol.58
, pp. 3455-3460
-
-
Cunningham, J.M.1
Christensen, E.R.2
Tester, D.J.3
Kim, C.Y.4
Roche, P.C.5
Burgart, L.J.6
Thibodeau, S.N.7
-
7
-
-
0028152314
-
Loss of the wild-type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
-
Hemminki, A., Peltomaki, P., Mecklin, J.P., Jarvinen, H., Salovaara, R., Nystrom-Lahti, M., de la Chapelle, A. and Aaltonen, L.A. (1994) Loss of the wild-type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nature Genet., 8, 405-410.
-
(1994)
Nature Genet.
, vol.8
, pp. 405-410
-
-
Hemminki, A.1
Peltomaki, P.2
Mecklin, J.P.3
Jarvinen, H.4
Salovaara, R.5
Nystrom-Lahti, M.6
De La Chapelle, A.7
Aaltonen, L.A.8
-
8
-
-
9444271133
-
Spontaneous intestinal carcinomas and skin neoplasmas in MSH2-deficient mice
-
Reitmair, A.H., Redstonm, M., Cai, J.C., Chuang, T.C.Y., Bjerknes, M., Cheng, H., Hay, K., Gallinger, S., Bapat, B. and Mak, T.W. (1996) Spontaneous intestinal carcinomas and skin neoplasmas in MSH2-deficient mice. Cancer Res., 56, 3842-3849.
-
(1996)
Cancer Res.
, vol.56
, pp. 3842-3849
-
-
Reitmair, A.H.1
Redstonm, M.2
Cai, J.C.3
Chuang, T.C.Y.4
Bjerknes, M.5
Cheng, H.6
Hay, K.7
Gallinger, S.8
Bapat, B.9
Mak, T.W.10
-
9
-
-
0031882250
-
Tumor susceptibility and spontaneous mutation in mice deficient in MLH1, PMSI and PMS2 DNA mismatch repair genes
-
Prolla, T.A., Baker, S.M., Harris, A.C., Tsao, J.L., Yao, X., Bronner, C.E., Zhang, B., Gordon, M., Reneker, J., Arnheim, N., Shibata, D., Bradley, A. and Liskay, R.M. (1998) Tumor susceptibility and spontaneous mutation in mice deficient in MLH1, PMSI and PMS2 DNA mismatch repair genes. Nature Genet., 18, 276-279.
-
(1998)
Nature Genet.
, vol.18
, pp. 276-279
-
-
Prolla, T.A.1
Baker, S.M.2
Harris, A.C.3
Tsao, J.L.4
Yao, X.5
Bronner, C.E.6
Zhang, B.7
Gordon, M.8
Reneker, J.9
Arnheim, N.10
Shibata, D.11
Bradley, A.12
Liskay, R.M.13
-
10
-
-
0029099989
-
Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis
-
Baker, S.M., Bronner, C.E., Zhang, L., Plug, A.W., Robatzek, M., Warren, G., Elliott, E.A., Yu, J., Ashley,T., Arnheim, N., Flavell, R.A. and Liskay, R.M. (1995) Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis. Cell, 82, 309-319.
-
(1995)
Cell
, vol.82
, pp. 309-319
-
-
Baker, S.M.1
Bronner, C.E.2
Zhang, L.3
Plug, A.W.4
Robatzek, M.5
Warren, G.6
Elliott, E.A.7
Yu, J.8
Ashley, T.9
Arnheim, N.10
Flavell, R.A.11
Liskay, R.M.12
-
11
-
-
0029101616
-
Inactivation of the mouse MSH2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer
-
De Wind, N., Dekker, M., Berns, A., Radman, M. and te Riele, H. (1995) Inactivation of the mouse MSH2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination and predisposition to cancer. Cell, 82, 321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
De Wind, N.1
Dekker, M.2
Berns, A.3
Radman, M.4
Te Riele, H.5
-
12
-
-
0029111463
-
MSH2 deficient mice are viable and susceptible to lymphoid tumors
-
Reitmair, A.H., Schmits, R., Ewel, A., Bapat, B., Redstonm, M., Mitri, A., Waterhouse, P., Mittrucker, H.W., Wakeman, A., Liu, B., Thomason, A., Griesser, H., Gallinger, S., Ballhausen, W.G., Fishel, R. and Mak, T.W. (1995) MSH2 deficient mice are viable and susceptible to lymphoid tumors. Nature Genet., 11, 64-70.
-
(1995)
Nature Genet.
, vol.11
, pp. 64-70
-
-
Reitmair, A.H.1
Schmits, R.2
Ewel, A.3
Bapat, B.4
Redstonm, M.5
Mitri, A.6
Waterhouse, P.7
Mittrucker, H.W.8
Wakeman, A.9
Liu, B.10
Thomason, A.11
Griesser, H.12
Gallinger, S.13
Ballhausen, W.G.14
Fishel, R.15
Mak, T.W.16
-
13
-
-
0033559202
-
Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice
-
Edelmann, W., Yang, K., Kuraguchi, M., Heyer, J., Lia, M., Kneitz, B., Fan, K., Brown, A.M.C., Lipkin, M. and Kucherlapati, R. (1999) Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice. Cancer Res., 59, 1301-1307.
-
(1999)
Cancer Res.
, vol.59
, pp. 1301-1307
-
-
Edelmann, W.1
Yang, K.2
Kuraguchi, M.3
Heyer, J.4
Lia, M.5
Kneitz, B.6
Fan, K.7
Brown, A.M.C.8
Lipkin, M.9
Kucherlapati, R.10
-
14
-
-
8944262831
-
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis
-
Reitmair, A.H., Cai, J.C., Matthew, B., Redstonm, M., Cheng, H., Pind, M.T.L., Hay, K., Mitri, A., Bapat, B.V., Mak, T.W. and Gallinger, S. (1996) MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis. Cancer Res., 56, 2922-2926.
-
(1996)
Cancer Res.
, vol.56
, pp. 2922-2926
-
-
Reitmair, A.H.1
Cai, J.C.2
Matthew, B.3
Redstonm, M.4
Cheng, H.5
Pind, M.T.L.6
Hay, K.7
Mitri, A.8
Bapat, B.V.9
Mak, T.W.10
Gallinger, S.11
-
15
-
-
0032521201
-
-/-; Min mice
-
-/-; Min mice. Cancer Res., 58, 1087-1089.
-
(1998)
Cancer Res.
, vol.58
, pp. 1087-1089
-
-
Baker, S.M.1
Harris, A.C.2
Tsao, J.L.3
Flath, T.J.4
Bronner, C.E.5
Gordon, M.6
Shibata, D.7
Liskay, R.M.8
-
16
-
-
0031984094
-
Mouse models for hereditary nonpolyposis colorectal cancer
-
De Wind, N., Dekker, M., Van Rossum, A., Van der Valk, M. and te Riele, H. (1998) Mouse models for hereditary nonpolyposis colorectal cancer. Cancer Res., 58, 248-255.
-
(1998)
Cancer Res.
, vol.58
, pp. 248-255
-
-
De Wind, N.1
Dekker, M.2
Van Rossum, A.3
Van Der Valk, M.4
Te Riele, H.5
-
17
-
-
0030820546
-
Intestinal stem cell division and genetic diversity. A computer and experimental analysis
-
Tsao, J.L., Davis, S.D., Baker, S.M., Liskay, R.M. and Shibata, D. (1997) Intestinal stem cell division and genetic diversity. A computer and experimental analysis. Am. J. Pathol., 151, 573-579.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 573-579
-
-
Tsao, J.L.1
Davis, S.D.2
Baker, S.M.3
Liskay, R.M.4
Shibata, D.5
-
18
-
-
0027452417
-
Genomic instability occurs in colorectal carcinomas but not in adenomas
-
Young, J., Leggett, B., Gustafson, C., Ward, M., Searle, J., Thomas, L., Buttenshaw, R. and Chenevix-Trench, G. (1993) Genomic instability occurs in colorectal carcinomas but not in adenomas. Hum. Mutat., 2, 351-354.
-
(1993)
Hum. Mutat.
, vol.2
, pp. 351-354
-
-
Young, J.1
Leggett, B.2
Gustafson, C.3
Ward, M.4
Searle, J.5
Thomas, L.6
Buttenshaw, R.7
Chenevix-Trench, G.8
-
19
-
-
0029078288
-
Genetic instability associated with adenoma to carcinoma progression in hereditary nonpolyposis colon cancer
-
Jacoby, R.F., Marshall, D.J., Kailas, S., Schlack, S., Harms, B. and Love, R. (1995) Genetic instability associated with adenoma to carcinoma progression in hereditary nonpolyposis colon cancer. Gastroenterology, 109, 73-82.
-
(1995)
Gastroenterology
, vol.109
, pp. 73-82
-
-
Jacoby, R.F.1
Marshall, D.J.2
Kailas, S.3
Schlack, S.4
Harms, B.5
Love, R.6
-
20
-
-
0029061638
-
Mismatch repair deficiency in phenotypically normal human cells
-
Parsons, R., Li, G.-M., Longley, M., Modrich, P., Liu, B., Berkk, T., Hamilton, S.R., Kinzler, K.W. and Vogelstein, B. (1995) Mismatch repair deficiency in phenotypically normal human cells. Science, 268, 738-740.
-
(1995)
Science
, vol.268
, pp. 738-740
-
-
Parsons, R.1
Li, G.-M.2
Longley, M.3
Modrich, P.4
Liu, B.5
Berkk, T.6
Hamilton, S.R.7
Kinzler, K.W.8
Vogelstein, B.9
-
21
-
-
0027938331
-
Loss of APC + in intestinal adenomas from Min mice
-
Luongo, C., Moser, A.R., Gledhill, S. and Dove, W.F. (1994) Loss of APC + in intestinal adenomas from Min mice. Cancer Res., 54, 5947-5952.
-
(1994)
Cancer Res.
, vol.54
, pp. 5947-5952
-
-
Luongo, C.1
Moser, A.R.2
Gledhill, S.3
Dove, W.F.4
-
22
-
-
0028051822
-
Inactivation of both APC allele in human and mouse tumors
-
Levy, D.B., Smith, K.J., Beazer-Barclay, Y., Hamilton, S.R., Vogelstein, B. and Kinzler, K.W. (1994) Inactivation of both APC allele in human and mouse tumors. Cancer Res., 54, 5953-5958.
-
(1994)
Cancer Res.
, vol.54
, pp. 5953-5958
-
-
Levy, D.B.1
Smith, K.J.2
Beazer-Barclay, Y.3
Hamilton, S.R.4
Vogelstein, B.5
Kinzler, K.W.6
-
23
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell, S.M., Zilz, N., Beazer-Barclay, Y. Bryan, T.M., Hamilton, S.R., Thibodeau, S.N., Vogelstein, B. and Kinzler, K.W. (1992) APC mutations occur early during colorectal tumorigenesis. Nature, 359, 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
24
-
-
0027452417
-
Genomic instability occurs in colorectal carcinomas but not in adenomas
-
Young, J., Leggett, B., Gustafson, C., Ward, M., Searle J., Thomas, L., Buttenshaw, R. and Chenevix-Trench, G. (1993) Genomic instability occurs in colorectal carcinomas but not in adenomas. Hum. Mutat., 2, 351-354.
-
(1993)
Hum. Mutat.
, vol.2
, pp. 351-354
-
-
Young, J.1
Leggett, B.2
Gustafson, C.3
Ward, M.4
Searle, J.5
Thomas, L.6
Buttenshaw, R.7
Chenevix-Trench, G.8
-
25
-
-
0033615013
-
Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT
-
Qin, X., Liu, L. and Gerson, S.L. (1999) Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT. Oncogene, 18, 4394-4400.
-
(1999)
Oncogene
, vol.18
, pp. 4394-4400
-
-
Qin, X.1
Liu, L.2
Gerson, S.L.3
-
26
-
-
0032863569
-
Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis
-
Qin, X., Zhou, H., Liu, L. and Gerson, S.L. (1999) Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis. Carcinogenesis, 20, 1667-1673.
-
(1999)
Carcinogenesis
, vol.20
, pp. 1667-1673
-
-
Qin, X.1
Zhou, H.2
Liu, L.3
Gerson, S.L.4
-
27
-
-
0343253893
-
PMS2-deficient mice are hypersensitive to GI tumor induction by azoxymethane and protected by MGMT overexpression
-
Qin, X., Zhou, H., Liu, L. and Gerson, S.L. (1999) PMS2-deficient mice are hypersensitive to GI tumor induction by azoxymethane and protected by MGMT overexpression. Proc. Am. Assoc. Cancer Res., 40, 57.
-
(1999)
Proc. Am. Assoc. Cancer Res.
, vol.40
, pp. 57
-
-
Qin, X.1
Zhou, H.2
Liu, L.3
Gerson, S.L.4
-
28
-
-
0025058718
-
DNA adduct formation and unscheduled DNA synthesis in rat esophagus in vivo after treatment with N-methyl-N-nitrosourea
-
Qin, X., Nakatsuru, Y., Kohyama, K. and Ishikawa, T. (1990) DNA adduct formation and unscheduled DNA synthesis in rat esophagus in vivo after treatment with N-methyl-N-nitrosourea. Carcinogenesis, 11, 235-238.
-
(1990)
Carcinogenesis
, vol.11
, pp. 235-238
-
-
Qin, X.1
Nakatsuru, Y.2
Kohyama, K.3
Ishikawa, T.4
-
29
-
-
0028179771
-
DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea
-
Qin, X., Zarkovic, M., Nakatsuru, Y. Arai, M., Oda, H. and Ishikawa, T. (1994) DNA adduct formation and assessment of aberrant crypt foci in vivo in the rat colon mucosa after treatment with N-methyl-N-nitrosourea. Carcinogenesis, 15, 851-855.
-
(1994)
Carcinogenesis
, vol.15
, pp. 851-855
-
-
Qin, X.1
Zarkovic, M.2
Nakatsuru, Y.3
Arai, M.4
Oda, H.5
Ishikawa, T.6
-
30
-
-
0033600130
-
6-methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea
-
6-methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea. Oncogene, 18, 3783-3787.
-
(1999)
Oncogene
, vol.18
, pp. 3783-3787
-
-
Allay, E.1
Veigl, M.2
Gerson, S.L.3
-
33
-
-
0030479125
-
Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
-
Liu, L., Markowitz, S. and Gerson, S.L. (1996) Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res., 56, 5375-5379.
-
(1996)
Cancer Res.
, vol.56
, pp. 5375-5379
-
-
Liu, L.1
Markowitz, S.2
Gerson, S.L.3
-
34
-
-
0031906084
-
The role of DNA mismatch repair in drug resistance
-
Fink, D., Aebi, S. and Howell, S.B. (1998) The role of DNA mismatch repair in drug resistance. Clin. Cancer Res., 4, 1-6.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 1-6
-
-
Fink, D.1
Aebi, S.2
Howell, S.B.3
-
35
-
-
0032477876
-
Tissues of MSH2-deficient mice demonstrate hypermutability on exposure to a DNA methylating agent
-
Andrew, S.E., McKinnon, M., Cheng, B.S., Francis, A., Penney, J., Reitmair, A.H., Mak, T.W. and Jirik, F.R. (1998) Tissues of MSH2-deficient mice demonstrate hypermutability on exposure to a DNA methylating agent. Proc. Natl Acad. Sci. USA, 95, 1126-1130.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 1126-1130
-
-
Andrew, S.E.1
McKinnon, M.2
Cheng, B.S.3
Francis, A.4
Penney, J.5
Reitmair, A.H.6
Mak, T.W.7
Jirik, F.R.8
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