메뉴 건너뛰기




Volumn 30, Issue 4, 2000, Pages 1002-1009

Naive T lymphocytes traffic to inflamed central nervous system, but require antigen recognition for activation

Author keywords

Autoimmune; Bystander; Cytokine; EAE

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CYTOKINE; MYELIN BASIC PROTEIN; OVALBUMIN; T LYMPHOCYTE RECEPTOR;

EID: 0034004454     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(200004)30:4<1002::AID-IMMU1002>3.0.CO;2-2     Document Type: Article
Times cited : (89)

References (53)
  • 2
    • 0028959239 scopus 로고
    • The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis
    • Sriram, S. and Owens, T., The immunology of multiple sclerosis and its animal model, experimental allergic encephalomyelitis. Neurol. Clin. 1995. 13: 51-73.
    • (1995) Neurol. Clin. , vol.13 , pp. 51-73
    • Sriram, S.1    Owens, T.2
  • 3
    • 43949160470 scopus 로고
    • Inflammatory cytokines in the brain: Does the CNS shape immune responses?
    • Owens, T., Renno, R., Taupin, V. and Krakowski, M., Inflammatory cytokines in the brain: does the CNS shape immune responses? Immunol. Today 1994. 15: 566-571.
    • (1994) Immunol. Today , vol.15 , pp. 566-571
    • Owens, T.1    Renno, R.2    Taupin, V.3    Krakowski, M.4
  • 4
    • 0030176121 scopus 로고    scopus 로고
    • Lymphocyte migration into tissue - The paradigm derived from CD4 subsets
    • Bradley, L. M. and Watson, S. R., Lymphocyte migration into tissue - The paradigm derived from CD4 subsets. Curr. Opin. Immunol. 1996. 8: 312-320.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 312-320
    • Bradley, L.M.1    Watson, S.R.2
  • 5
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E. C. and Picker, L. J., Lymphocyte homing and homeostasis. Science 1996. 272: 60-66.
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 6
    • 0025981021 scopus 로고
    • T-lymphocyte entry into the central nervous system
    • Mickey, W., Hsu, B. and Kimura, H., T-lymphocyte entry into the central nervous system. J. Neurosci. Res. 1991. 28: 254-260.
    • (1991) J. Neurosci. Res. , vol.28 , pp. 254-260
    • Mickey, W.1    Hsu, B.2    Kimura, H.3
  • 7
    • 0031689716 scopus 로고    scopus 로고
    • The fate of T cells in the brain: Veni, vidi, vici and veni, mori
    • Lehmann, P. V., The fate of T cells in the brain: veni, vidi, vici and veni, mori. Am. J. Pathol. 1998. 153: 677-680.
    • (1998) Am. J. Pathol. , vol.153 , pp. 677-680
    • Lehmann, P.V.1
  • 8
    • 0029000750 scopus 로고
    • Functional evidence for epitope spreading in the releasing pathology of MS
    • McRae, B. L., Vanderburg, C. L., Dal Canto, M. and Miller, S., Functional evidence for epitope spreading in the releasing pathology of MS. J. Exp. Med. 1995. 182: 75-85.
    • (1995) J. Exp. Med. , vol.182 , pp. 75-85
    • McRae, B.L.1    Vanderburg, C.L.2    Dal Canto, M.3    Miller, S.4
  • 10
    • 0026630032 scopus 로고
    • + T cells that induce experimental allergic encephalomyelitis
    • + T cells that induce experimental allergic encephalomyelitis. J. Neuroimmunol. 1992. 40: 57-69.
    • (1992) J. Neuroimmunol. , vol.40 , pp. 57-69
    • Zeine, R.1    Owens, T.2
  • 11
    • 0021279150 scopus 로고
    • Homing of Lyt-2+ and Lyt-2-T cells subsets and B lymphocytes to the central nervous system of mice with acute experimental allergic encephalomyelitis
    • Trotter, J. and Steinman, A. L., Homing of Lyt-2+ and Lyt-2-T cells subsets and B lymphocytes to the central nervous system of mice with acute experimental allergic encephalomyelitis. J. Immunol. 1984. 132: 2919-2923.
    • (1984) J. Immunol. , vol.132 , pp. 2919-2923
    • Trotter, J.1    Steinman, A.L.2
  • 12
    • 0032209150 scopus 로고    scopus 로고
    • Immune cell entry to CNS - A focus for immunoregulation of EAE
    • Owens, T., Tran, E., Hassan-Zahraee, M. and Krakowski, M., Immune cell entry to CNS - a focus for Immunoregulation of EAE. Res. Immunol. 1998. 149: 781-789.
    • (1998) Res. Immunol. , vol.149 , pp. 781-789
    • Owens, T.1    Tran, E.2    Hassan-Zahraee, M.3    Krakowski, M.4
  • 14
    • 0025771604 scopus 로고
    • Adhesion-related molecules in the central nervous system. Upregulation correlates with inflammatory cell influx during relapsing experimental autoimmune encephalomyelitis
    • Cannella, B., Cross, A. and Raine, C. S., Adhesion-related molecules in the central nervous system. Upregulation correlates with inflammatory cell influx during relapsing experimental autoimmune encephalomyelitis. Lab. Invest. 1991. 65: 23-31.
    • (1991) Lab. Invest. , vol.65 , pp. 23-31
    • Cannella, B.1    Cross, A.2    Raine, C.S.3
  • 15
    • 0027529932 scopus 로고
    • Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma
    • Baron, J., Madri, J., Ruddle, N., Hashim, G. and Janeway, C., Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 1993. 177: 57-68.
    • (1993) J. Exp. Med. , vol.177 , pp. 57-68
    • Baron, J.1    Madri, J.2    Ruddle, N.3    Hashim, G.4    Janeway, C.5
  • 16
    • 0027190748 scopus 로고
    • Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis
    • Hulkower, K., Brosnan, C., Aquino, D., Cammer, W., Kulshrestha, S., Guida, M., Rapoport, D. and Berman, J., Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis. J. Immunol. 1993. 150: 2525-2533.
    • (1993) J. Immunol. , vol.150 , pp. 2525-2533
    • Hulkower, K.1    Brosnan, C.2    Aquino, D.3    Cammer, W.4    Kulshrestha, S.5    Guida, M.6    Rapoport, D.7    Berman, J.8
  • 17
    • 0028803845 scopus 로고
    • An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell mediated autoimmune disease, experimental autoimmune encephalomyelitis
    • Karpus, W. J., Lukacs, N. W., McRae, B. L., Stricter, R. M., Kunkel, S. L. and Miller, S. D., An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell mediated autoimmune disease, experimental autoimmune encephalomyelitis. J. Immunol. 1995. 155: 5003-5010.
    • (1995) J. Immunol. , vol.155 , pp. 5003-5010
    • Karpus, W.J.1    Lukacs, N.W.2    McRae, B.L.3    Stricter, R.M.4    Kunkel, S.L.5    Miller, S.D.6
  • 18
    • 0031033952 scopus 로고    scopus 로고
    • Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis
    • Glabinski, A., Tani, M., Stricter, R., Tuohy, V. and Ransohoff, R., Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am. J. Pathol. 1997. 150: 617-630.
    • (1997) Am. J. Pathol. , vol.150 , pp. 617-630
    • Glabinski, A.1    Tani, M.2    Stricter, R.3    Tuohy, V.4    Ransohoff, R.5
  • 20
    • 0027367157 scopus 로고
    • Homing of T cells to the central nervous system throughout the course of relapsing experimental autoimmune encephalomyelitis in Thy-1 congenic mice
    • Skundric, D. S., Kim, C., Tse, H. Y. and Raine, C. S., Homing of T cells to the central nervous system throughout the course of relapsing experimental autoimmune encephalomyelitis in Thy-1 congenic mice. J. Neuroimmunol. 1993. 46: 113-121.
    • (1993) J. Neuroimmunol. , vol.46 , pp. 113-121
    • Skundric, D.S.1    Kim, C.2    Tse, H.Y.3    Raine, C.S.4
  • 21
    • 0029083243 scopus 로고
    • Influx of nonactivated T lymphocytes into the cerebrospinal fluid during relapse of multiple sclerosis
    • Oksaranta, O., Tarvonen, S., Ilonen, J., Poikonen, K., Reunanen, M., Panelius, M. and Salonen, R., Influx of nonactivated T lymphocytes into the cerebrospinal fluid during relapse of multiple sclerosis. Ann. Neurol. 1994. 38: 456-468.
    • (1994) Ann. Neurol. , vol.38 , pp. 456-468
    • Oksaranta, O.1    Tarvonen, S.2    Ilonen, J.3    Poikonen, K.4    Reunanen, M.5    Panelius, M.6    Salonen, R.7
  • 22
    • 0031874342 scopus 로고    scopus 로고
    • Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry
    • Horwitz, M. S., Bradley, L. M., Harbertson, J., Krahl, T., Lee, J. and Sarvetnick, N., Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry. Nature Medicine 1998. 4: 781-785.
    • (1998) Nature Medicine , vol.4 , pp. 781-785
    • Horwitz, M.S.1    Bradley, L.M.2    Harbertson, J.3    Krahl, T.4    Lee, J.5    Sarvetnick, N.6
  • 23
    • 0032536447 scopus 로고    scopus 로고
    • An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease
    • Segal, B. M., Dwyer, B. K. and Shevach, E. M., An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease. J. Exp. Med. 1998. 187: 537-546.
    • (1998) J. Exp. Med. , vol.187 , pp. 537-546
    • Segal, B.M.1    Dwyer, B.K.2    Shevach, E.M.3
  • 24
    • 0030723360 scopus 로고    scopus 로고
    • + T cells cytokine profile in experimental allergic encephalomyelitis
    • + T cells cytokine profile in experimental allergic encephalomyelitis. Eur. J. Immunol. 1997. 27: 2840-2847.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2840-2847
    • Krakowski, M.L.1    Owens, T.2
  • 25
    • 0027319467 scopus 로고
    • + T cells as a mechanism for remission in experimental allergic encephalomyelitis
    • + T cells as a mechanism for remission in experimental allergic encephalomyelitis. J. Neuroimmunol. 1993. 44: 193-197.
    • (1993) J. Neuroimmunol. , vol.44 , pp. 193-197
    • Zeine, R.1    Owens, T.2
  • 26
    • 0028983573 scopus 로고
    • TNF a production by resident microglial cells and infiltrating leukocytes in experimental allergic encephalomyelitis: Regulation by Th1 cytokines
    • Renno, T., Krakowski, M. C., Piccirillo, Lin, J.-Y. and Owens, T., TNF a production by resident microglial cells and infiltrating leukocytes in experimental allergic encephalomyelitis: regulation by Th1 cytokines. J. Immunol. 1995. 154: 944-953.
    • (1995) J. Immunol. , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.C.2    Piccirillo3    Lin, J.-Y.4    Owens, T.5
  • 27
    • 0027168794 scopus 로고
    • The effect of cyclophosphamide treatment on lymphocyte subsets in the nonobese diabetic mouse: A comparison of various lymphoid organs
    • Zhang, Z. L., Georgiou, H. M. and Mandel, T. E., The effect of cyclophosphamide treatment on lymphocyte subsets in the nonobese diabetic mouse: a comparison of various lymphoid organs. Autoimmunity 1993. 15: 1-10.
    • (1993) Autoimmunity , vol.15 , pp. 1-10
    • Zhang, Z.L.1    Georgiou, H.M.2    Mandel, T.E.3
  • 28
    • 0031887891 scopus 로고    scopus 로고
    • Beyond inflammation: Site-directed immunotherapy
    • Lampson, L., Beyond inflammation: site-directed immunotherapy. Immunol. Today 1998. 19: 17-22.
    • (1998) Immunol. Today , vol.19 , pp. 17-22
    • Lampson, L.1
  • 29
    • 0030035947 scopus 로고    scopus 로고
    • Lymphocyte targeting of the central nervous system: A review of afferent and efferent CNS-immune pathways
    • Weller, R., Engelhardt, B. and Phillips, A. M., Lymphocyte targeting of the central nervous system: a review of afferent and efferent CNS-immune pathways. Brain Path. 1996. 6: 275-288.
    • (1996) Brain Path. , vol.6 , pp. 275-288
    • Weller, R.1    Engelhardt, B.2    Phillips, A.M.3
  • 30
    • 0032516797 scopus 로고    scopus 로고
    • Accumulation of passively transferred primed T cell independently of their antigen specificity following central nervous system trauma
    • Hirschberg, D. L., Moalem, G., He, J., Mor, F., Cohen, I. R. and Schwartz, M., Accumulation of passively transferred primed T cell independently of their antigen specificity following central nervous system trauma. J. Neuroimmunol. 1998. 89: 88-96.
    • (1998) J. Neuroimmunol. , vol.89 , pp. 88-96
    • Hirschberg, D.L.1    Moalem, G.2    He, J.3    Mor, F.4    Cohen, I.R.5    Schwartz, M.6
  • 31
    • 0023413923 scopus 로고
    • Immune reactivity in the nervous system: Modulation of T-lymphocyte activation by glial cells
    • Wekerle, H., Sun, D., Opereza-Wekerle, R. and Meyermann, R., Immune reactivity in the nervous system: modulation of T-lymphocyte activation by glial cells. J. Exp. Biol. 1987. 132: 43-57.
    • (1987) J. Exp. Biol. , vol.132 , pp. 43-57
    • Wekerle, H.1    Sun, D.2    Opereza-Wekerle, R.3    Meyermann, R.4
  • 32
    • 0025127157 scopus 로고
    • Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis
    • Cross, A. H., Cannella, B., Brosnan, C. F. and Raine, C. S., Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis. Lab Invest. 1990. 63: 162-170.
    • (1990) Lab Invest. , vol.63 , pp. 162-170
    • Cross, A.H.1    Cannella, B.2    Brosnan, C.F.3    Raine, C.S.4
  • 33
    • 0032076047 scopus 로고    scopus 로고
    • Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors
    • Sarukhan, A., Garcia, C., Lanoue, A. and von Boehmer, H., Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors. Immunity 1998. 8: 563-570.
    • (1998) Immunity , vol.8 , pp. 563-570
    • Sarukhan, A.1    Garcia, C.2    Lanoue, A.3    Von Boehmer, H.4
  • 34
    • 0032193213 scopus 로고    scopus 로고
    • Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from the blood, are prevented in macrophage-depleted mice
    • Tran, E., Hoekstra, K., van Rooijen, N., Dijkstra, C. and Owens, T., Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from the blood, are prevented in macrophage-depleted mice. J. Immunol. 1998. 161: 3767-3775.
    • (1998) J. Immunol. , vol.161 , pp. 3767-3775
    • Tran, E.1    Hoekstra, K.2    Van Rooijen, N.3    Dijkstra, C.4    Owens, T.5
  • 35
    • 0029848128 scopus 로고    scopus 로고
    • Microglia induce CD4 T lymphocyte final effector function and death
    • Ford, A. L., Foulcher, E., Lemckert, F. A. and Sedgwick, J. D., Microglia induce CD4 T lymphocyte final effector function and death. J. Exp. Med. 1996. 184: 1737-1745.
    • (1996) J. Exp. Med. , vol.184 , pp. 1737-1745
    • Ford, A.L.1    Foulcher, E.2    Lemckert, F.A.3    Sedgwick, J.D.4
  • 36
    • 0031802828 scopus 로고    scopus 로고
    • Tissue-specific up-regulation of B7-1 expression and function during the course of murine relapsing experimental autoimmune encephalomyelitis
    • Karandikar, N. J., Vanderlugt, C. L., Eagar, T., Tan, L., Bluestone, J. A. and Miller, S. D., Tissue-specific up-regulation of B7-1 expression and function during the course of murine relapsing experimental autoimmune encephalomyelitis. J. Immunol. 1998. 161: 192-199.
    • (1998) J. Immunol. , vol.161 , pp. 192-199
    • Karandikar, N.J.1    Vanderlugt, C.L.2    Eagar, T.3    Tan, L.4    Bluestone, J.A.5    Miller, S.D.6
  • 37
    • 0032964119 scopus 로고    scopus 로고
    • Disproportionate recruitment of CD8+ T cells into the central nervous system by professional antigen-presenting cells
    • Carson, M. J., Reilly, C. R., Sutcliffe, J. G. and Lo, D., Disproportionate recruitment of CD8+ T cells into the central nervous system by professional antigen-presenting cells. Am. J. Pathol. 1999. 154: 481-494.
    • (1999) Am. J. Pathol. , vol.154 , pp. 481-494
    • Carson, M.J.1    Reilly, C.R.2    Sutcliffe, J.G.3    Lo, D.4
  • 38
    • 0023194190 scopus 로고
    • In vivo labelling of blood T cells: Rapid traffic into cerbrospinal fluid in multiple sclerosis
    • Hafler, D. and Weiner, H., In vivo labelling of blood T cells: rapid traffic into cerbrospinal fluid in multiple sclerosis. Ann. Neurol. 1987. 22: 89-93.
    • (1987) Ann. Neurol. , vol.22 , pp. 89-93
    • Hafler, D.1    Weiner, H.2
  • 41
    • 0028819138 scopus 로고
    • The subarachnoid space as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis
    • Shin, T., Kojima, T., Tanuma, N., Ishihara, Y. and Matsumoto, Y., The subarachnoid space as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 1995. 56: 171-178.
    • (1995) J. Neuroimmunol. , vol.56 , pp. 171-178
    • Shin, T.1    Kojima, T.2    Tanuma, N.3    Ishihara, Y.4    Matsumoto, Y.5
  • 42
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann, P., Forsthuber, T., Miller, A. and Sercarz, E., Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 1992. 358: 155-157.
    • (1992) Nature , vol.358 , pp. 155-157
    • Lehmann, P.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.4
  • 43
    • 0031179652 scopus 로고    scopus 로고
    • Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis
    • Brabb, T., Goldrath, A. W., von Dassow, P., Paez, A., Liggitt, H. D. and Governman, J., Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis. J. Immunol. 1997. 159: 497-507.
    • (1997) J. Immunol. , vol.159 , pp. 497-507
    • Brabb, T.1    Goldrath, A.W.2    Von Dassow, P.3    Paez, A.4    Liggitt, H.D.5    Governman, J.6
  • 44
    • 0030945996 scopus 로고    scopus 로고
    • Bystander activation of cytotoxic T cells: Studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model
    • Ehl, S., Hombach, J., Aichele, P., Hengartner, H. and Zinkernagel, R., Bystander activation of cytotoxic T cells: studies on the mechanism and evaluation of in vivo significance in a transgenic mouse model. J. Exp. Med. 1997. 185: 1241-1251.
    • (1997) J. Exp. Med. , vol.185 , pp. 1241-1251
    • Ehl, S.1    Hombach, J.2    Aichele, P.3    Hengartner, H.4    Zinkernagel, R.5
  • 45
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and type I interferon in vivo
    • Tough, D., Borrow, P. and Sprent, J., Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 1996. 272: 1947-1950.
    • (1996) Science , vol.272 , pp. 1947-1950
    • Tough, D.1    Borrow, P.2    Sprent, J.3
  • 47
    • 0028839339 scopus 로고
    • Presence of T cells with activated and memory phenotypes in inflammatory spinal cord lesions
    • Barten, D., Clark, R. and Ruddle, N., Presence of T cells with activated and memory phenotypes in inflammatory spinal cord lesions. J. Immunol. 1995. 155: 5409-5418.
    • (1995) J. Immunol. , vol.155 , pp. 5409-5418
    • Barten, D.1    Clark, R.2    Ruddle, N.3
  • 49
    • 0029957071 scopus 로고    scopus 로고
    • Interferon-gamma confers resistance to experimental allergic encephalomyelitis
    • Krakowski, M. and Owens, T., Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur. J. Immunol. 1996. 26: 1641-1646.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1641-1646
    • Krakowski, M.1    Owens, T.2
  • 50
    • 0024968476 scopus 로고
    • Stable cell membrane labelling
    • Horan, P. and Slezak, S., Stable cell membrane labelling. Nature 1989. 340: 167-168.
    • (1989) Nature , vol.340 , pp. 167-168
    • Horan, P.1    Slezak, S.2
  • 51
    • 0020623652 scopus 로고
    • The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody
    • Haskins, K., Kubo, R., White, J., Pigeon, M., Kappler, J. and Marrack, P., The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 1983. 157: 1149-1169.
    • (1983) J. Exp. Med. , vol.157 , pp. 1149-1169
    • Haskins, K.1    Kubo, R.2    White, J.3    Pigeon, M.4    Kappler, J.5    Marrack, P.6
  • 52
    • 0023787404 scopus 로고
    • Purification and partial characterization of a receptor protein for mouse interferon gamma
    • Basu, M. Pace, J., Pinson, D., Hayes, M., Trotta, P. and Russell, A. P., Purification and partial characterization of a receptor protein for mouse interferon gamma. Proc. Natl. Acad. Sci. USA 1988. 85: 6282-6286.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 6282-6286
    • Basu, M.1    Pace, J.2    Pinson, D.3    Hayes, M.4    Trotta, P.5    Russell, A.P.6
  • 53
    • 0024346410 scopus 로고
    • A monoclonal antibody to murine CD45RB distinguishes CD4 T cell populations that produce different cytokines
    • Bottomly, K., Luqman, M., Greenbaum, L., Carding, S., West, J., Pasqualini, T. and Murphy, D., A monoclonal antibody to murine CD45RB distinguishes CD4 T cell populations that produce different cytokines. Eur. J. Immunol. 1989. 19: 617-623.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 617-623
    • Bottomly, K.1    Luqman, M.2    Greenbaum, L.3    Carding, S.4    West, J.5    Pasqualini, T.6    Murphy, D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.