Environmental signaling: A biological context for endocrine disruption

Environmental Health Perspectives

Volumn 106, Issue SUPPL. 1, 1998, Pages 5-10

  Cheek, Ann Oliver ^a   Vonier, Peter M ^a,b   Oberdörster, Eva ^a   Burow, Bridgette Collins ^a,b   McLachlan, John A ^a,b  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TULANE UNIVERSITY   (United States)

Author keywords

Endocrine disruption; Environmental estrogens; Hormone receptors; Hormones; Signaling

Indexed keywords

ESTROGEN; HORMONE RECEPTOR; PHYTOESTROGEN; STEROID; XENOBIOTIC AGENT;

BIOAVAILABILITY; DRUG MECHANISM; DRUG METABOLISM; ENDOCRINE SYSTEM; ENVIRONMENTAL EXPOSURE; HUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0031955841     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.2307/3433910     Document Type: Review

References (90)

1. Peters NK, Forst JW, Long SR. A plant flavone, lutiolin, induces expression of Rhizobium meliloti nodulation genes. Science 233:977-980 (1986).
2. Redmond JW, Batley M, Djordjevic MA, Innes RW, Kuempel PL, Rolfe BG. Flavones induce expression of nodulation genes in Rhizobium. Nature 323:632-635 (1986).
3. Peters NK, Long SR. Alfalfa root exudates and compounds which promote or inhibit induction of Rhizobium meliloti nodulation genes. Plant Physiol 88:396-400 (1988).
4. Firmin JL, Wilson KE, Rossen L, Johnston AWB. Flavonoid activation of nodulation genes in Rhizobium reversed by other compounds present in plants. Nature 324:90-92 (1986).
5. Baker, ME. Evolution of regulation of steroid-mediated intercellular communication in vertebrates: insights from flavonoids, signals that mediate plant-Rhizobia symbiosis. J Steroid Biochem Mol Biol 41:301-308 (1992).
6. Bennets HW, Underwood EJ, Shier FL. A specifie breeding problem of sheep on subterranean clover pastures in Western Australia. Aust Vet J 22:2-12 (1946).
7. Hughes CL Jr. Phytochemical mimicry of reproductive hormones and modulation of herbivore fertility by phytoestrogens. Environ Health Perspect 78:171-175 (1988).
8. Aldercreutz H. Phytoestrogens: epidemiology and a possible role in cancer protection. Estrogens in the Environment, III: Global Health Implications. Environ Health Perspect 103 (SuPPl 7):103-112 (1995).
9. . 9. Wu AH, Ziegler RG, Horn-Ross PL, Nomura AMY, West DW, Kolonel LN, Rosenthal JF, Hoover RN, Pike MC. Tofu and risk of breast cancer in Asian-Americans. Cancer Epidemiol Biomarkers Prev 5:901-906 (1996).
10. Anthony MS, Clarkson TB, Hughes CL, Morgan TM, Burke GL. Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys. J Nutr 126:43-50 (1996).
11. Ingram D, Sanders K, Kolybaba M, Lopez D. Case-control study of phyto-oestrogens and breast cancer. Lancet 350:990-994 (1997).
12. Atkinson S, Atkinson MJ, Detection of estradiol-17β during a mass coral spawn. Coral Reefs 11:33-35 (1992).
13. Waddy S, Aiken D, deKleijn D. Control of growth and : reproduction. In: Biology of the Lobster Homarus americanus (Factor JR, ed). New York:Academic Press, 1995.
14. Baldwin WS, Leblanc G. In vivo biotransformation of testosterone by phase I and II detoxification enzymes and their modulation of 20-hydroxyecdysone in Daphnia magna. Aquat Toxicol 29:103-117 (1994).
15. Feral C, LeGall S. The influence of a pollutant factor (tributyltin) on the neuroendocrine mechanism responsible for the occurrence of a penis in the females of Ocenebra erinacea. In: Molluscan Neuroendocrinology (Lever J, Boer H, eds). Amsterdam:North Holland, 1983;173-175.
16. LeBlanc G. Susceptibility of invertebrates to endocrine-disrupting environmental chemicals. In: Environmental Endocrine Disrupters: An Evolutionary Perspective (Guillette LJ Jr, ed). London:Taylor and Francis, in press.
17. Colborn T, vom Saal FS, Soto AM. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect 101:378-384 (1993).
18. Safe SH, Zacharewski T. Organochlorine exposure and risk for breast cancer. Prog Clin Biol Res 396:133-145 (1997).
19. Sharpe RM, Skakkebaek NE. Are oestrogens involved in falling sperm counts and disorders of the male reporductive tract? Lancet 341:1392-1395 (1993).
20. Herman-Giddens ME, Slora EJ, Wasserman RC, Bourdony CJ, Bhapkar MV, Koch GG, Hasemeier CM. Secondary sexual characteristics and menses in young girls seen in office practice: a study from the pediatric research in office settings network. Pediatrics 99:505-511 (1997).
21. Tanner JM. Trend towards earlier menarche in London, Oslo, Copenhagen, the Netherlands, and Hungary. Nature 243:95-96 (1973).
22. Wolff MS, Toniolo P, Lee E, Rivera M, Dubin N. Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst 85:648-652 (1993).
23. Fry DM, Toone CK. DDT-induced feminization of gull embryos. Science 213:922-924 (1981).
24. Palmiter RD, Mulvhill ER. Estrogenic activity of the insecticide kepone on the chicken oviduct. Science 201:356-358 (1978).
25. Purdom CE, Hardiman PA, Bye VJ, Eno NC, Tyler CR, Sumpter JP. Estrogenic effects of effluent from sewage treatment works. Chem Ecol 8:275-285 (1994).
26. White R, Jobling S, Hoare SA, Sumpter JP, Parker MG. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 135:175-182 (1994).
27. Sumpter JP. IBC conference report, 1997.
28. Klotz DM, McLachlan JA Arnold, SF. Identification of chemicals with estrogenic activity using a combination of in vitro assays. Environ Health Perspect 104:1084-1089 (1996).
29. Coldham NG, Dave M, Sivapathasundaram S, McDonnell DP, Connor C, Sauer MJ. Evaluation of a recombinant yeast cell estrogen screening assay. Environ Health Perspect 105:734-742 (1997).
30. Jennings ML, Percival HF, Woodward AR. Evaluation of alligator hatchling and egg removal from three Florida lakes. Proc Annu Conf Southeast Assoc Fish Wildl Agencies 42:283-294 (1988).
31. Guillette LJ Jr, Pickford DB, Crain DA, Rooney AA, Percival HF. Reduction in penis size and plasma testosterone concentrations in juvenile alligators living in a contaminated environment. Gen Comp Endocrinol 101:32-42 (1996).
32. Guillette LJ Jr, Gross TS, Masson GR, Matter JM, Percival HF, Woodward AR. Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators living in a contaminated environment. Gen Comp Endocrinol 101:32-42 (1996).
33. Bergeron JM, Crews D, McLachlan JA. PCBs as environmental estrogens: turtle sex determination as a biomarker of environmental contamination. Environ Health Perspect 102:780-781 (1994).
34. Bettin C, Oehlmann J, Stroben E. TBT-induced imposex in marine neogastropods is mediated by an increasing androgen level. Helgol Meeresunters 50:299-317 (1996).
35. Ronis MJJ, Mason, AZ. The metabolism of testosterone by the periwinkle (Littorina littorea) in vitro and in vivo: effects of tribuytl tin [sic]. Mar Environ Res 42:161-166 (1996).
36. Oberdörster E, Rittschof D, McClellan-Green P. Testosterone metabolism in imposex and normal Ilyanassa obsoleta: a comparison of field and TBT Cl-induced imposex. Mar Pollut Bull (in press).
37. Evans SM, Leksono T, McKinnell PD. Tributyltin pollution: a diminishing problem following legislation limiting the use of TBT-based anti-fouling paints. Mar Pollut Bull 30:14-21 (1995).
38. Gibbs PE, Bryan GW. Reproductive failure in populations of the dog-whelk, Nucella lapillus, caused by imposex induced by tributyltin from antifouling paints. J Mar Biol Assoc U.K. 66:767-777 (1986).
39. Baldwin WS, Milam DL, LeBlanc GA. Physiological and biochemical perturbations in Daphnia magna following exposure to the model environmental estrogen diethylstilbestrol. Environ Toxicol Chem 14:945-952 (1995).
40. Baldwin W, Graham S, Shea D, LeBlanc G. Metabolic androgenization of female Daphnia magna by the xenoestrogen 4-nonylphenol. Environ Toxicol Chem 16:1905-1911 (1997).
41. Parks L, LeBlanc G. Reductions in steroid hormone biotransformation/elimination as a biomarker of pentachlorophenol chronic toxicity. Aquat Toxicol 34:291-303 (1996).
42. Oberdörster E, LeBlanc G, Rittschof D. Alteration of testosterone metabolism after chronic exposure of Daphnia magna to tributyltin. Aquat Toxicol (in press).
43. Oberdörster E, Rittschof D, McClellan-Green P. Induction of cytochrome P450 3A and heat shock protein by tributyltin in blue crab, Callinectes sapidus. Aquat Toxicol (in press).
44. Lee RF, Noone T. Effect of Reproductive toxicants on lipovitellin in female blue crabs, Callinectes sapidus. Mar Environ Res 39:151-154 (1995).
45. Garreau B, Vallette G, Adlercreutz H, Wahala K, Makela T, Benassaayag C, Nunez EA. Phytoestrogens: new ligands for rat and human α-fetoprotein. Biochim Biophys Acta 1094:339-345 (1991).
46. Sheenan DM, Young M. Diethylstilbestrol and estradiol binding to serum albumin and pregnancy plasma of rat and human. Endocrinology 104:1442-1446 (1979).
47. Swartz SK, Soloff MS, Suriano JR. Binding of estrogens by αfetoprotein in rat amniotic fluid. Biochim Biophys Acta 338:480-486 (1974).
48. McLachlan JA, Korach KS, Metzler M. Bioavailability as a determinant in the transplacental toxicity of diethylstilbstrol. In: Role of Pharmacology in Prenatal and Perinatal Toxicology (Neubert D, Merker H-J, Nau H, Langman J eds). Stuttgart:Georg Thieme, 1978;147-155.
49. vom Saal FS, Nagel SC, Palanza P, Boechler M, Parmigiana S, Welshons WV. Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice. Toxicol Lett 77:343-350 (1995).
50. Stack G, Gorski J. The ontogeny of estrogen responsiveness reexamined: the differential effectiveness of diethylstilbestrol and estradiol on uterine deoxyribonucleic acid synthesis in neonatal rats. Endocrinology 112:2142-2146 (1983).
51. Arnold SF, Robinson MK, Notides AC, Guillette LJ Jr, McLachlan JA. A yeast estrogen screen for examining the relative exposure of cells to natural and xenoestrogens. Environ Health Perspect 104:544-548 (1996).
52. Arnold SF, Collins BM, Robinson MK, Guillette LJ Jr McLachlan JA. Differential interaction of natural and synthetic estrogens with extracellular binding proteins in a yeast estrogen screen. Steroids 61:642-646 (1996).
53. Bain LJ, LeBlanc GA. Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoproten. Toxicol Appl Pharmacol 141:288-298 (1996).
54. Castro AF, Altenberg GA (1996). Inhibition of drug transport by genistein in multi-drug-resistant cells expressing P-glycoprotein. Biochem Pharmacol 53:89-93.
55. Mahe Y, Lemoine Y, Kuchler K. The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo. J Biol Chem 271:25167-25172 (1996).
56. Norman, AW, Litwack G. Hormones. New York:Academic Press, 1987.
57. Klaassen C, Amdiur M, Doull J. Casarett and Doull's Toxicology: The Basic Science of Poisons. New York: McGraw-Hill, 1996.
58. Welch RM, Levin W, Conney AH. Estrogenic activity of DDT and its analogs. Toxicol Appl Pharmacol 14:358-366 (1969).
59. Bitman J, Cecil HC. Estrogenic activity of DDT analogs and polychlorinated biphenyls. J Agr Food Chem 18:1108-1112 (1970).
60. Korach KS, Sarver P, Chae K, McLachlan JA, McKinney JD. Estrogen receptor-binding activity of polychlorinated hydroxy biphenyls: conformational restricted probes. Mol Pharmacol 33:120-126 (1988).
61. Tran DQ, Jin L, Guillette LJ Jr, McLachlan JA Arnold SF. The estrogenic activity of selected polychlorinated biphenyls with estrogen receptor expressed in Saccharomyces cerevisiae. Steroids, (in press).
62. Collins BM, McLachlan, JA Arnold, SF. The estrogenic and antiestrogenic activites of various phytochemicals with the human estrogen receptor expressed in yeast. Steroids 63:364-371 (1997).
63. Martin PM, Horwitz KB, Ryan DS, McGuire WL. Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology 103:1860-1867 (1978).
64. Miksicek RJ Commonly occurring plant flavanoids have estrogenic activity. Mol Pharmacol 44:37-43 (1993).
65. Zava DT, Duwe G. Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro. Nutr Cancer 27:31-40 (1997).
66. Routledge EJ, Sumpter JP. Structural features of alkylphenolic chemicals associated with estrogenic activity. J Biol Chem 272:3280-3288 (1997).
67. Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA. Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 93:5925-5930 (1996).
68. Paech K, Webb P, Kuiper GGJM, Nilsson S, Gustafsson J-A, Kushner PJ, Scanlan TS. Differential ligand activation of estrogen receptors Era and Erβ at API sites. Science 277:1508-1510 (1997).
69. Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138:863-870 (1997).
70. Kelce WR, Stone CR, Laws SC, Gray LE, Kemppainen JA, Wilson EM. Persistent DDT metabolite p,p′-DDE is a potent androgen receptor antagonist. Nature 735:581-585 (1995).
71. Chang CS, Liao SS Topographic recognition of cyclic hydrocarbons and related compounds by receptors for androgens, estrogens, and glucocorticoids. J Steroid Biochem 27:123-31 (1987).
72. Cook JC; Mullin LS; Frame SR; Biegel LB Investigation of a mechanism for Leydig cell tumorigenesis by linuron in rats. Toxicol Appl Pharmacol 119(2): 195-204 (1993)
73. Gray LE, Ostby JS, Kelce WR. Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat. Toxicot Appl Pharmacol 129:46-52 (1994).
74. Klotz DM, Ladlie BL, Vonier PM, McLachlan JA Arnold SF. Inhibition of 17β-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insectides. Life Sci 60:1467-1475 (1997).
75. Vonier PM, Crain AD, Guillette LJ Jr, McLachlan JA Arnold, SF. Interaction chemicals with the estrogen and progesterone receptors from the American alligator. Environ Health Perspect 104:1318-1322 (1996).
76. Klotz DM, Arnold SF, McLachlan JA. Identification and characterization of 0,p′-DDT and its metabolites as inhibitors of progesterone activity in yeast and mammalian cells. Mol Cell Endocrinol 129:63-71 (1997).
77. Harmon MA, Boehm MF, Heyman RA, Mangelsdorf DJ. Activation of mammalian retinoid X receptors by the insect growth regulator methoprene. Proc Natl Acad Sci USA 92:6157-6160 (1995).
78. Repetto R, Baliga SS. Pesticides and the immune system: the public health risks. Executive summary. Cent Eur J Public Health 4:263-265 (1996).
79. Goldey ES, Kehn LS, Lau C, Rehnberg GL, Crofton KM. Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone concentrations and causes hearing deficits in rats. Toxicol Appl Pharmacol 135:77-88 (1995).
80. Schantz SL, Byung-Woun S, Moshtaghian J, Amin S. Developmental exposure to polychlorinated biphenyls or dioxin: do changes in thyroid function mediate effects on spatial learning? Am Zool 37:399-408 (1997).
81. Chen JY-C, Guo Y-L, Hsu C-C, Rogan WJ. Cognitive development of Yu-Cheng ('oil disease') children prenatally exposed to heat degraded PCBs. JAMA 268:3213-3218 (1992).
82. Jacobson JL, Jacobon SW, Humphrey HE. Effects of in utero exposure to polychlorinated biphenyls and related contaminants on cognitive functioning in young children. J Pediatr 116:38-45 (1990).
83. Jacobson JL, Jacobson SW. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. N Engl J Med 335:783-789 (1996).
84. Koopman-Esseboom C, Morse DC, Weisglas-Kuperus N, Lutkeschipholt IJ, Van Der Paauw CG, Tuinstra LGMT, Brouwer A, Sauer PJJ. Effects of dioxins and polychlorinated biphenyls on thyroid hormone status of pregnant women and their infants. Pediatr Res 36:468-473 (1994).
85. Juberg DR, Stuenkel EL, Loch-Caruso R. The chlorinated insecticide l, l-dichloro-2,2-bis(4-chlorophenyl)ethane (p,p′DDD) increases intracellular calcium in rat myometrial smooth muscle cells. Toxicol Appl Pharmacol 135:147-155 (1995).
86. 2+ sequestration in rat cerebellum by polychlorinated diphenyl ether cogners and analogs: structure-activity relationships. Toxicol Appl Pharmacol 138:251-261 (1996).
87. Rokos CL, Ledwith BJ. Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells. J Biol Chem 272:13452-13457 (1997).
88. Shen K, Novak RF. DDT stimulates c-erb2, c-met, and STAT tyrosine phosphorylation, Grb2-Sos association, MAPK phosphorylation, and proliferation of human breast epithelial cells. Biochem Biophys Res Commun 231:17-21 (1997).
89. Steinmetz R, Young PC, Caperell-Grant A, Gize EA, Madhukar BV, Ben-Jonathan N, Bigsby RM. Novel estrogenic action of the pesticide residue β-hexachlorocyclohexane in human breast cancer cells. Cancer Res. 56:5403-5409 (1996).
90. Ignar-Trowbridge DM, Nelson KG, Bidwell MC, Curtis SW, Washburn TF, McLachlan JA, Korach KS. Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor. Proc Natl Acad Sci USA 89:4658-4662 (1992).