Reversible modulation of human factor xa activity with phosphonate esters: Media effects

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 3, 2000, Pages 549-556

  Enyedy, Edith J ^a   Kovach, Ildiko M ^a  

^a CATHOLIC UNIVERSITY OF AMERICA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; BLOOD CLOTTING FACTOR 10A; BUFFER; CALCIUM CHLORIDE; PHOSPHOLIPID; PHOSPHONIC ACID ESTER; SODIUM CHLORIDE;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; ENANTIOMER; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME REACTIVATION; PH; STEREOCHEMISTRY;

BINDING SITES; ENZYME ACTIVATION; ENZYME INHIBITORS; ESTERIFICATION; FACTOR VA; FACTOR XA; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LIGANDS; LIPID BILAYERS; MODELS, CHEMICAL; PHOSPHATIDYLSERINES; PHOSPHOLIPIDS; PHOSPHONIC ACIDS; SERINE; STEREOISOMERISM;

EID: 0033998802     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00321-1     Document Type: Article

References (30)

1. Mann, K. G. In Hemostasis and Thrombosis. Basic Priciples and Clinical Practice; Colman, R. W.; Hirsh, J.; Marder, V. J.; Salzman, E. W., Eds.; J .B. Lippincott:, Philadelphia, 1994; pp 184-199.
2. Kerr M.A., Grahn D.T., Walsh K.A., Neurath H. Biochemistry. 17:1978;2645.
3. Comfurius P., Smeets E.F., Willem G.M., Bevers E.M., Zwaal R.F.A. Biochemistry. 33:1994;10319.
4. Di Scipio R.G., Hermodson M.A., Davie E.W. Biochemistry. 16:1977;5253.
5. Pryzdial E.L., Kessler O.E. J. Biol. Chem. 271:1996;16621.
6. Pryzdial E.L., Kessler G.E. J. Biol. Chem. 271:1996;16614.
7. Patthy L. Methods Enzymol. 222:1993;10.
8. Padmanabhan K., Padmanabhan K.P., Tulinsky A., Park C.H., Bode W., Huber R., Blankenship D.T., Cardin A.D., Kmsiel W. J. Mol. Biol. 232:1993;947.
9. Brandstetter H., Kuhne A., Bode W., Huber R., Von der Saal W., Wirthensohn K., Engh R.A. J. Biol. Chem. 271:1997;29988.
10. Husten E.J., Esmon C.T., Johnson A.E. J. Biol. Chem. 262:1987;12953.
11. Rezaie A.R. J. Biol. Chem. 271:1996;23807.
12. Kamata K., Kwamoto H., Honma T., Iwamata T., Kim S.H. Proc. Natl. Acad. Sci. 95:1998;6630.
13. Mao S.S., Przysiecky C.Y., Krueger J.A., Cooper C.M., Lewis S.D., Joyce J., Lellis C., Garsky V.M., Sardana M., Shafer J.A. J. Biol. Chem. 273:1998;30086.
14. Wong A.G., Gunn A.C., Ku P., Hollenbach S.J., Sinha U. Thromb. Haemost. 77:1997;1143.
15. Lin P.-H., Laibelman A.M., Sinha U. Throm. Res. 88:1997;365.
16. Wolf D.L., Lin P.H., Hollenbach S., Wong A., Phillips D.R., Sinha U. Blood. 86:1995;4153.
17. Zhao Q., Kovach I.M., Bencsura A., Papathanassiu A. Biochemistry. 33:1994;8128.
18. Zhao Q., Kovach I.M. Bioorg. Med. Chem. 4:1996;523.
19. Kovach I.M., McKay L. Bioorg. Med. Chem. Lett. 2:1992;1735.
20. Enyedy E.J., Kovach I.M. Bioorg. Med. Chem. 35:1997;1531.
21. Koppaka V., Wang J., Banerjee M., Lentz B.R. Biochemistry. 35:1996;7482.
22. Krishnaswamy S., Church W.R., Nesheim M.E., Mann K.G. J. Biol. Chem. 262:1987;3291.
23. Krishnaswamy S., Walker R.K. Biochemistry. 36:1997;3319.
24. Kovach I.M., Zhao Q., Keane M., Reyes R. J. Am. Chem. Soc. 115:1993;10471.
25. Lieske C.N., Mejza S.J., Steinberg G.M., Pikulin J.N., Lennox W.J., Ash A.B., Blumbergs P. J. Agric. Food Chem. 17:1969;255.
26. Leatherbarrow, R. J. GraFit; Erithacus Software Ltd. Staines, UK, 1992; pp 1-288.
27. Mayer L.D., Hope M.J., Cullis P.R. Biochim. Biophys. Acta. 858:1986;161.
28. Hope M.J., Bally M.B., Webb G., Cullis P.R. Biochim. Biophys. Acta. 812:1985;55.
29. Sokolovsky M., Riordan J.F., Vallee B.L. Biochemistry. 5:1966;3582.
30. Riordan J.F., Vallee B.L. Methods Enzymol. 25:1972;515.