Modulation of human α-thrombin activity with phosphonate ester inhibitors

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 8, 1997, Pages 1531-1541

  Enyedy, Edith J ^a   Kovach, Ildiko M ^a  

^a CATHOLIC UNIVERSITY OF AMERICA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHONIC ACID ESTER; THROMBIN; THROMBIN INHIBITOR;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG ACTIVITY; ENANTIOMER; ENZYME ACTIVE SITE; ENZYME INACTIVATION; KINETICS; MODULATION; REACTION ANALYSIS; STEREOCHEMISTRY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ESTERS; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; PROTEIN CONFORMATION; STEREOISOMERISM; THROMBIN;

EID: 0030818244     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00099-0     Document Type: Article

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