Promoter region methylation does not account for the frequent loss of expression of the Fas gene in colorectal carcinoma

British Journal of Cancer

Volumn 82, Issue 1, 2000, Pages 131-135

  Butler, L M ^a   Dobrovic, A ^a,b   Bianco, T ^a,b   Cowled, P A ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b QUEEN ELIZABETH HOSPITAL   (Australia)

Author keywords

Apoptosis; Gene silencing; Island; Methylation

Indexed keywords

DNA; FAS ANTIGEN;

ADENOMA; ARTICLE; CLINICAL ARTICLE; COLON MUCOSA; COLORECTAL CARCINOMA; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE SILENCING; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION SITE; SOUTHERN BLOTTING;

EID: 0033988337     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.1999.0889     Document Type: Article

References (31)

1. Ahuja N, Li Q, Mohan AL, Baylin SB and Issa J-PJ (1998) Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 58: 5489-5494
2. Baker SJ, Markowitz S, Fearon ER, Willson JKV and Vogelstein B (1990) Suppression of human colorectal carcinoma cell growth by vvild-type p53. Science 249: 912-915
3. Baylin SB, Herman JG, Graff JR, Vertino PM and Issa J-P (1998) Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res 72: 141-196
4. Behrmann I, Walczak H and Krammer PH (1994) Structure of the human APO-I gene. Eur J Immunol 24: 3057-3062
5. Butler LM, Hewett PJ, Butler WJ and Cowled PA (1998) Down-regulation of Fas gene expression in colon cancer is not a result of allelic loss or gene rearrangement. Br J Cancer 77: 1454-1459
6. Butler LM, Hewett PJ, Fitridge RA and Cowled PA (1999) Deregulation of apoptosis in colorectal cancer: theoretical and therapeutic implications. Aust NZ J Surg 69: 88-94
7. Chan H, Bartos DP and Owen-Schaub LB (1999) Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment. Mol Cell Biol 19: 2098-2108
8. Cheng J, Liu C, Koopman WJ and Mountz JD (1995) Characterization of human Fas gene. J Immunol 154: 1239-1245
9. Frommer M, McDonald LE, Millar DS, Collis CM, Watt F, Grigg GW, Molloy PL and Paul CL (1992) A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci USA 89: 1827-1831
10. Goelz SE, Vogelstein B, Hamilton SR and Feinberg AP (1985) Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 228: 187-190
11. Hall PA, Coates PJ, Ansari B and Hopwood D (1994) Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 107: 3569-3577
12. Hiltunen MO, Alhonen L, Koistinaho J, Myöhänen S, Pääkkönen M, Marin S, Kosma V-M and Jänne J (1997) Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma. Int J Cancer 70: 644-648
13. Iacopetta BJ, Harmon D, Spagnolo DV, House AK and Kay PH (1997) Hypermethylation of the Myf-3 gene in human colorectal cancer. Anticancer Res 17: 429-432
14. Issa J-P, Ottaviano YL, Celano P, Hamilton SR, Davidson NE and Baylin SB (1994) Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 7: 536-540
15. Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, Goldman H, Jessup JM and Kolodner R (1997) Methylation of the hMLHI promoter correlates with lack of expression of hMLHI in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 57: 808-811
16. Kuo MH and Allis CD (1998) Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays 20: 615-626
17. Leithäuser F, Dhein J, Mechtersheimer G, Koretz K, Brüderlein S, Henne C, Schmidt A, Debatin K-M, Krammer PH and Möller P (1993) Constitutive and induced expression of APO-I, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest 69: 415-429
18. Matsumoto Y, Hayakawa A, Tamada Y, Mori H and Ohashi M (1996) Upregulated expression of Fas antigen on cultured human keratinocytes with induction of apoptosis by cisplatin. Arch Dermatol Res 288: 267-269
19. Möller P, Koretz K, Leithauser F, Brüderlein S, Henne C, Quentmeier A and Krammer PH (1994) Expression of APO-I (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium. Int J Cancer 57: 371-377
20. Muller M, Strand S, Hug H, Heinemann E-M, Walczak H, Hofmann WJ, Stremmel W, Krammer PH and Galle PR (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-I/Fas) rcceplor/ligand system and involves activation of wild-type p53. J Clin Invest 99: 403-413
21. Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang W-W, Kruzel E and Radinsky R (1995) Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-I expression. Mol Cell Biol 15: 3032-3040
22. Reap EA, Roof K, Maynor K, Borrero M, Booker J and Cohen PL (1997) Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions. Proc Natl Acad Sci USA 94: 5750-5755
23. Reinke V and Lozano G (1997) The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo. Oncogene 15: 1527-1534
24. Rudert F, Visser E, Forbes L, Lindridge E, Wang Y and Watson J (1995) Identification of a silencer, enhancer, and basal promoter region in the human CD95 (Fas/APO-I) gene. DNA Cell Biol 14: 931-937
25. wild-type cancer cells treated with ionizing radiation. Int J Cancer 73: 757-762
26. Silverman AL, Park J-G, Hamilton SR, Gazdar AF, Luk GD and Baylin SB (1989) Abnormal methylation of the calcitonin gene in human colonic neoplasms. Cancer Res 49: 3468-3473
27. Streeck RE (1980) Single-strand and double-strand cleavage at half-modified and fully modified recognition sites for the restriction nucleases Sau3A and Taql. Gene 12: 267-275
28. Tamura T, Aoyama N, Saya H, Haga H, Futami S, Miyamoto M, Koh T, Ariyasu T, Tachi M, Kasuga M and Takahashi R (1995) Induction of Fas-mediated apoptosis in p53-transfected human colon carcinoma cells. Oncogene 11: 1939-1946
29. Trauth BC, Klas C, Peters AMJ, Matzku S, Möller P, Falk W, Debatin K-M and Krammer PH (1989) Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245: 301-304
30. Vogelstein B, Fearon ER, Kern SE, Hamilton SR, Preisinger AC, Nakamura Y and White R (1989) Allelotype of colorectal carcinomas. Science 244: 207-211
31. Yonehara S, Ishii A and Yonehara M (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-down-regulated with the receptor of tumor necrosis factor. J Exp Med 169: 1747-1756