Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction

European Journal of Immunology

Volumn 30, Issue 1, 2000, Pages 164-173

  Zhou, Naiming ^a   Luo, Zhaowen ^a   Hall, James W ^a   Luo, Jiansong ^a   Han, Xiaobing ^a   Huang, Ziwei ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Chemokine; Chemokine receptor; HIV; Mutagenesis; Signal transduction

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CCR5; GLYCOPROTEIN GP 120; MUTANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR MODEL; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

CHEMOKINES; HIV ENVELOPE PROTEIN GP120; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, CCR5; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033987285     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200001)30:1<164::AID-IMMU164>3.0.CO;2-X     Document Type: Article

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