In Vitro permeability of eight β-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry

Journal of Mass Spectrometry

Volumn 33, Issue 7, 1998, Pages 607-614

  Caldwell, Gary W ^a   Easlick, Scott M ^b   Gunnet, Joseph ^b   Masucci, John A ^b   Demarest, Keith ^b  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

^b NONE

Author keywords

adrenoceptor antagonist drugs; Apparent permeability; Caco 2; Liquid chromatography electrospray ionization mass spectrometry

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ANALYTIC METHOD; ARTICLE; DIFFUSION; DRUG PENETRATION; DRUG TRANSPORT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEASUREMENT; PRIORITY JOURNAL; RADIOACTIVITY;

ACEBUTOLOL; ADRENERGIC BETA-ANTAGONISTS; ALPRENOLOL; ATENOLOL; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHROMATOGRAPHY, LIQUID; EPITHELIAL CELLS; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MASS SPECTROMETRY; METOPROLOL; MOLECULAR STRUCTURE; OXPRENOLOL; PINDOLOL; PROPRANOLOL; RESEARCH DESIGN; TIMOLOL;

EID: 0031830624     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(199807)33:7<607::AID-JMS672>3.0.CO;2-O     Document Type: Article

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