메뉴 건너뛰기




Volumn 278, Issue 1 47-1, 2000, Pages

Effects of chloride channel inhibitors on H2O2-induced renal epithelial cell injury

Author keywords

Chloride channels; LLC PK1 cell; Necrosis; Oxidant stress

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; ADENOSINE TRIPHOSPHATE; CELL DNA; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CHLORIDE ION; EFENAMIC ACID; HYDROGEN PEROXIDE; ISETHIONIC ACID; LACTATE DEHYDROGENASE; NIFLUMIC ACID; TRYPAN BLUE;

EID: 0033967015     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2000.278.1.f83     Document Type: Article
Times cited : (20)

References (46)
  • 2
    • 0025016281 scopus 로고
    • Reactive oxygen molecule-mediated injury in endothelial and renal tubular epithelial cells in vitro
    • Andreoli, S. P., and J. A. McAteer. Reactive oxygen molecule-mediated injury in endothelial and renal tubular epithelial cells in vitro. Kidney Int. 38: 785-794, 1990.
    • (1990) Kidney Int. , vol.38 , pp. 785-794
    • Andreoli, S.P.1    McAteer, J.A.2
  • 5
    • 0029155812 scopus 로고
    • ATP depletion and inactivation of an ATP-sensitive taurine channel by classic ion channel blockers
    • Ballatori, N., A. T. Truong, P. S. Jackson, K. Strange, and J. L. Boyer. ATP depletion and inactivation of an ATP-sensitive taurine channel by classic ion channel blockers. Mol. Pharmacol. 48: 472-476, 1995.
    • (1995) Mol. Pharmacol. , vol.48 , pp. 472-476
    • Ballatori, N.1    Truong, A.T.2    Jackson, P.S.3    Strange, K.4    Boyer, J.L.5
  • 6
    • 0030250416 scopus 로고    scopus 로고
    • Volume-sensitive chloride channels blocked by neuroprotective drugs in human glial cells (U-138MG)
    • Bausch, A. R., and G. Roy. Volume-sensitive chloride channels blocked by neuroprotective drugs in human glial cells (U-138MG). Glia 18: 73-77, 1996.
    • (1996) Glia , vol.18 , pp. 73-77
    • Bausch, A.R.1    Roy, G.2
  • 7
    • 0003079139 scopus 로고
    • Lactic dehydrogenase
    • edited by H. U. Bergmeyer. New York: Academic
    • Bergmeyer, H. U., E. Bernt, and B. Hess. Lactic dehydrogenase. In: Methods of Enzymatic Analysis, edited by H. U. Bergmeyer. New York: Academic, 1963, p. 736-743.
    • (1963) Methods of Enzymatic Analysis , pp. 736-743
    • Bergmeyer, H.U.1    Bernt, E.2    Hess, B.3
  • 8
    • 0019476174 scopus 로고
    • Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation
    • Birnboim, H. C., and J. J. Jevcak. Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation. Canc. Res. 41: 1889-1892, 1981.
    • (1981) Canc. Res. , vol.41 , pp. 1889-1892
    • Birnboim, H.C.1    Jevcak, J.J.2
  • 9
    • 0029084127 scopus 로고
    • Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury
    • Chen, J., J. A. Cohn, and L. J. Mandel. Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury. Proc. Nat. Acad. Sci. USA 92: 7495-7499, 1995.
    • (1995) Proc. Nat. Acad. Sci. USA , vol.92 , pp. 7495-7499
    • Chen, J.1    Cohn, J.A.2    Mandel, L.J.3
  • 10
    • 1342318009 scopus 로고    scopus 로고
    • Reversibility/irreversibility of anoxia-induced plasma membrane permeabilization
    • Chen, J., and L. J. Mandel. Reversibility/irreversibility of anoxia-induced plasma membrane permeabilization (Abstract). J. Am. Soc. Nephrol. 8: 584, 1997.
    • (1997) J. Am. Soc. Nephrol. , vol.8 , pp. 584
    • Chen, J.1    Mandel, L.J.2
  • 11
    • 0030664309 scopus 로고    scopus 로고
    • Role of water and electrolyte influxes in anoxic plasma membrane disruption
    • Chen, J., and L. J. Mandel. Role of water and electrolyte influxes in anoxic plasma membrane disruption. Am. J. Physiol. Cell Physiol. 273: C1341-C1348, 1997.
    • (1997) Am. J. Physiol. Cell Physiol. , vol.273
    • Chen, J.1    Mandel, L.J.2
  • 14
    • 0028355697 scopus 로고
    • Method for recovering ATP content and mitochondrial function after chemical anoxia in renal cell cultures
    • Doctor, R. B., R. Bacallao, and L. J. Mandel. Method for recovering ATP content and mitochondrial function after chemical anoxia in renal cell cultures. Am. J. Physiol. Cell Physiol. 266: C1803-C1811, 1994.
    • (1994) Am. J. Physiol. Cell Physiol. , vol.266
    • Doctor, R.B.1    Bacallao, R.2    Mandel, L.J.3
  • 15
    • 0031779795 scopus 로고    scopus 로고
    • Development of porous defects in plasma membranes of adenosine triphosphate-depleted Madin-Darby canine kidney cells and its inhibition by glycine
    • Dong, Z., Y. Patel, P. Saikumar, J. M. Weinberg, and M. A. Venkatachalam. Development of porous defects in plasma membranes of adenosine triphosphate-depleted Madin-Darby canine kidney cells and its inhibition by glycine. Lab. Invest. 78: 657-668, 1998.
    • (1998) Lab. Invest. , vol.78 , pp. 657-668
    • Dong, Z.1    Patel, Y.2    Saikumar, P.3    Weinberg, J.M.4    Venkatachalam, M.A.5
  • 17
    • 0030011376 scopus 로고    scopus 로고
    • The role of the calcium-dependent enzymes nitric oxide synthase and calpain in hypoxia-induced proximal tubule injury
    • Edelstein, C. L., M. M. Yaqoob, and R. W. Schrier. The role of the calcium-dependent enzymes nitric oxide synthase and calpain in hypoxia-induced proximal tubule injury. Renal Failure 18: 501-511, 1996.
    • (1996) Renal Failure , vol.18 , pp. 501-511
    • Edelstein, C.L.1    Yaqoob, M.M.2    Schrier, R.W.3
  • 18
    • 0028220530 scopus 로고
    • Removal of extracellular sodium prevents anoxia-induced injury in freshly dissociated rat CA1 hippocampal neurons
    • Friedman, J. E., and G. G. Haddad. Removal of extracellular sodium prevents anoxia-induced injury in freshly dissociated rat CA1 hippocampal neurons. Brain Res. 641: 57-64, 1994.
    • (1994) Brain Res. , vol.641 , pp. 57-64
    • Friedman, J.E.1    Haddad, G.G.2
  • 21
    • 0028029012 scopus 로고
    • The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding
    • Jackson, P. S., R. Morrison, and K. Strange. The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding. Am. J. Physiol. Cell Physiol. 267: C1203-C1209, 1994.
    • (1994) Am. J. Physiol. Cell Physiol. , vol.267
    • Jackson, P.S.1    Morrison, R.2    Strange, K.3
  • 22
    • 0030798072 scopus 로고    scopus 로고
    • Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin a
    • Kaushal, G. P., N. Ueda, and S. V. Shah. Role of caspases (ICE/CED 3 proteases) in DNA damage and cell death in response to a mitochondrial inhibitor, antimycin A. Kidney Int. 52: 438-445, 1997.
    • (1997) Kidney Int. , vol.52 , pp. 438-445
    • Kaushal, G.P.1    Ueda, N.2    Shah, S.V.3
  • 23
    • 0015820012 scopus 로고
    • Cell swelling: A factor in ischemic tissue injury
    • Leaf, A. Cell swelling: a factor in ischemic tissue injury. Circulation 48: 455-458, 1973.
    • (1973) Circulation , vol.48 , pp. 455-458
    • Leaf, A.1
  • 24
    • 0019503531 scopus 로고
    • Intracellular electrolyte composition following renal ischemia
    • Mason, J., F. Beck, A. Dorge, R. Rick, and K. Thurau. Intracellular electrolyte composition following renal ischemia. Kidney Int. 20: 61-70, 1981.
    • (1981) Kidney Int. , vol.20 , pp. 61-70
    • Mason, J.1    Beck, F.2    Dorge, A.3    Rick, R.4    Thurau, K.5
  • 25
    • 0027983515 scopus 로고
    • Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion
    • McManus, M., C. Serhan, P. Jackson, and K. Strange. Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. Am. J. Physiol. Cell Physiol. 267: C266-C271, 1994.
    • (1994) Am. J. Physiol. Cell Physiol. , vol.267
    • McManus, M.1    Serhan, C.2    Jackson, P.3    Strange, K.4
  • 26
    • 0028219343 scopus 로고
    • Strychnine and glycine protect renal proximal tubules from various nephrotoxicants and act in the late phase of necrotic cell injury
    • Miller, G. W., E. A. Lock, and R. G. Schnellmann. Strychnine and glycine protect renal proximal tubules from various nephrotoxicants and act in the late phase of necrotic cell injury. Toxicol. Appl. Pharmacol. 125: 192-197, 1994.
    • (1994) Toxicol. Appl. Pharmacol. , vol.125 , pp. 192-197
    • Miller, G.W.1    Lock, E.A.2    Schnellmann, R.G.3
  • 27
    • 0027236187 scopus 로고
    • Cytoprotection by inhibition of chloride channels: The mechanism of action of glycine and strychnine
    • Miller, G. W., and R. G. Schnellmann. Cytoprotection by inhibition of chloride channels: the mechanism of action of glycine and strychnine. Life Sci. 53: 1211-1215, 1993.
    • (1993) Life Sci. , vol.53 , pp. 1211-1215
    • Miller, G.W.1    Schnellmann, R.G.2
  • 28
    • 0028338427 scopus 로고
    • A putative cytoprotective receptor in the kidney: Relation to the neuronal strychnine-sensitive glycine receptor
    • Miller, G. W., and R. G. Schnellmann. A putative cytoprotective receptor in the kidney: relation to the neuronal strychnine-sensitive glycine receptor. Life Sci. 55: 27-34, 1994.
    • (1994) Life Sci. , vol.55 , pp. 27-34
    • Miller, G.W.1    Schnellmann, R.G.2
  • 29
    • 0030815584 scopus 로고    scopus 로고
    • - channel: Fresh start to the molecular identity and volume sensor
    • - channel: fresh start to the molecular identity and volume sensor. Am. J. Physiol. Cell Physiol. 273: C755-C789, 1997.
    • (1997) Am. J. Physiol. Cell Physiol. , vol.273
    • Okada, Y.1
  • 31
    • 0030902041 scopus 로고    scopus 로고
    • Effects of chloride channel blockers on hypoxic injury in rat proximal tubules
    • Reeves, W. B. Effects of chloride channel blockers on hypoxic injury in rat proximal tubules. Kidney Int. 51: 1529-1534, 1997.
    • (1997) Kidney Int. , vol.51 , pp. 1529-1534
    • Reeves, W.B.1
  • 33
    • 0027948091 scopus 로고
    • Activation of potassium channels contributes to hypoxic injury in proximal tubules
    • Reeves, W. B., and S. V. Shah. Activation of potassium channels contributes to hypoxic injury in proximal tubules. J. Clin. Invest. 94: 2289-2294, 1994.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2289-2294
    • Reeves, W.B.1    Shah, S.V.2
  • 34
    • 0028370447 scopus 로고
    • Channels for ions and amino acids in kidney cultured cells (MDCK) during volume regulation
    • Roy, G., and U. Banderali. Channels for ions and amino acids in kidney cultured cells (MDCK) during volume regulation. J. Exp. Zool. 268: 121-126, 1994.
    • (1994) J. Exp. Zool. , vol.268 , pp. 121-126
    • Roy, G.1    Banderali, U.2
  • 35
    • 0026177314 scopus 로고
    • Elemental microanalysis of organelles in proximal tubules. II. Effects of oxygen deprivation
    • Spencer, A. J., A. LeFurgey, P. Ingram, and L. J. Mandel. Elemental microanalysis of organelles in proximal tubules. II. Effects of oxygen deprivation. J. Am. Soc. Nephrol. 1: 1321-1333, 1991.
    • (1991) J. Am. Soc. Nephrol. , vol.1 , pp. 1321-1333
    • Spencer, A.J.1    LeFurgey, A.2    Ingram, P.3    Mandel, L.J.4
  • 36
    • 0029972423 scopus 로고    scopus 로고
    • Cellular and molecular physiology of volume-sensitive anion channels
    • Strange, K., F. Emma, and P. S. Jackson. Cellular and molecular physiology of volume-sensitive anion channels. Am. J. Physiol. Cell Physiol. 270: C711-C730, 1996.
    • (1996) Am. J. Physiol. Cell Physiol. , vol.270
    • Strange, K.1    Emma, F.2    Jackson, P.S.3
  • 37
    • 0029103366 scopus 로고
    • Swelling-activated organic osmolyte efflux: A new role for anion channels
    • Strange, K., and P. S. Jackson. Swelling-activated organic osmolyte efflux: a new role for anion channels. Kidney Int. 48: 994-1003, 1995.
    • (1995) Kidney Int. , vol.48 , pp. 994-1003
    • Strange, K.1    Jackson, P.S.2
  • 38
    • 0027093953 scopus 로고
    • Endonuclease induced DNA damage and cell death in oxidant injury to renal tubular cells
    • Ueda, N., and S. V. Shah. Endonuclease induced DNA damage and cell death in oxidant injury to renal tubular cells. J. Clin. Invest. 90: 2593-2597, 1992.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2593-2597
    • Ueda, N.1    Shah, S.V.2
  • 39
    • 0026712124 scopus 로고
    • Role of intracellular calcium in hydrogen peroxide-induced renal tubular cell injury
    • Ueda, N., and S. V. Shah. Role of intracellular calcium in hydrogen peroxide-induced renal tubular cell injury. Am. J. Physiol. Renal Fluid Electrolyte Physiol. 263: F214-F221, 1992.
    • (1992) Am. J. Physiol. Renal Fluid Electrolyte Physiol. , vol.263
    • Ueda, N.1    Shah, S.V.2
  • 40
    • 0029126059 scopus 로고
    • Activation of a 15-kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis
    • Ueda, N., P. D. Walker, S. Hsu, and S. V. Shah. Activation of a 15-kDa endonuclease in hypoxia/reoxygenation injury without morphologic features of apoptosis. Proc. Nat. Acad. Sci. USA 92: 7202-7206, 1995.
    • (1995) Proc. Nat. Acad. Sci. USA , vol.92 , pp. 7202-7206
    • Ueda, N.1    Walker, P.D.2    Hsu, S.3    Shah, S.V.4
  • 41
    • 0030042591 scopus 로고    scopus 로고
    • Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels
    • Venkatachalam, M. A., J. M. Weinberg, Y. Patel, P. Saikumar, and Z. Dong. Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels. Kidney Int. 49: 449-460, 1996.
    • (1996) Kidney Int. , vol.49 , pp. 449-460
    • Venkatachalam, M.A.1    Weinberg, J.M.2    Patel, Y.3    Saikumar, P.4    Dong, Z.5
  • 43
    • 0030433182 scopus 로고    scopus 로고
    • Extracellular acidosis and chloride channel inhibitors act in the late phase of cellular injury to prevent death
    • Waters, S. L., and R. G. Schnellmann. Extracellular acidosis and chloride channel inhibitors act in the late phase of cellular injury to prevent death. J. Pharm. Exp. Therap. 278: 1-6, 1996.
    • (1996) J. Pharm. Exp. Therap. , vol.278 , pp. 1-6
    • Waters, S.L.1    Schnellmann, R.G.2
  • 44
    • 0023605596 scopus 로고
    • Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules
    • Weinberg, J. M., J. A. Davis, M. Abarzua, and T. Rajan. Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules. J. Clin. Invest. 80: 1446-1454, 1987.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1446-1454
    • Weinberg, J.M.1    Davis, J.A.2    Abarzua, M.3    Rajan, T.4
  • 45
    • 0028708952 scopus 로고
    • Role of intracellular pH during cytoprotection of proximal tubule cells by glycine or acidosis
    • Weinberg, J. M., J. A. Davis, N. F. Roeser, and M. A. Venkatachalam. Role of intracellular pH during cytoprotection of proximal tubule cells by glycine or acidosis. J. Am. Soc. Nephrol. 5: 1314-1323, 1994.
    • (1994) J. Am. Soc. Nephrol. , vol.5 , pp. 1314-1323
    • Weinberg, J.M.1    Davis, J.A.2    Roeser, N.F.3    Venkatachalam, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.