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Volumn 278, Issue 1 47-1, 2000, Pages

Pi3K signaling in the murine kidney inner medullary cell response to urea

Author keywords

Apoptosis; Hypertonicity; mIMCD3 cells; Sodium chloride; Stress

Indexed keywords

CELL PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; S6 KINASE; UREA;

EID: 0033964387     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2000.278.1.f155     Document Type: Article
Times cited : (32)

References (61)
  • 4
    • 0026179832 scopus 로고
    • Distinct mechanisms for the activation of the RSK kinases/MAP2 kinase/pp90rsk and pp70-S6 kinase signaling systems are indicated by inhibition of protein synthesis
    • Blenis, J., J. Chung, E. Erikson, D. A. Alcorta, and R. L. Erikson. Distinct mechanisms for the activation of the RSK kinases/MAP2 kinase/pp90rsk and pp70-S6 kinase signaling systems are indicated by inhibition of protein synthesis. Cell Growth Differ. 2: 279-285, 1991.
    • (1991) Cell Growth Differ. , vol.2 , pp. 279-285
    • Blenis, J.1    Chung, J.2    Erikson, E.3    Alcorta, D.A.4    Erikson, R.L.5
  • 5
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering, B. M. T., and P. J. Coffer. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376: 599-602, 1995.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.T.1    Coffer, P.J.2
  • 7
    • 0029773878 scopus 로고    scopus 로고
    • Urea-inducible Egr-1 transcription in renal inner medullary collecting duct (mIMCD3) cells is mediated by extracellular signal-regulated kinase activation
    • Cohen, D. M. Urea-inducible Egr-1 transcription in renal inner medullary collecting duct (mIMCD3) cells is mediated by extracellular signal-regulated kinase activation. Proc. Natl. Acad. Sci. USA 93: 11242-11247, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11242-11247
    • Cohen, D.M.1
  • 8
    • 0028090540 scopus 로고
    • Hyperosmotic urea increases transcription and synthesis of Egr-1 in murine inner medullary collecting duct (mIMCD3) cells
    • Cohen, D. M., W. W. Chin, and S. R. Gullans. Hyperosmotic urea increases transcription and synthesis of Egr-1 in murine inner medullary collecting duct (mIMCD3) cells. J. Biol. Chem. 269: 25865-25870, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 25865-25870
    • Cohen, D.M.1    Chin, W.W.2    Gullans, S.R.3
  • 12
    • 17544365900 scopus 로고    scopus 로고
    • Urea-inducibility of Egr-1 in murine inner medullary collecting duct cells is mediated by the serum response element and adjacent Ets motifs
    • Cohen, D. M., S. R. Gullans, and W. W. Chin. Urea-inducibility of Egr-1 in murine inner medullary collecting duct cells is mediated by the serum response element and adjacent Ets motifs. J. Biol. Chem. 271: 12903-12908, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12903-12908
    • Cohen, D.M.1    Gullans, S.R.2    Chin, W.W.3
  • 13
    • 0025946371 scopus 로고
    • Immediate early gene and HSP70 expression in hyperosmotic stress in MDCK cells
    • Cohen, D. M., J. C. Wasserman, and S. R. Gullans. Immediate early gene and HSP70 expression in hyperosmotic stress in MDCK cells. Am. J. Physiol. Cell Physiol. 261: C594-C601, 1991.
    • (1991) Am. J. Physiol. Cell Physiol. , vol.261
    • Cohen, D.M.1    Wasserman, J.C.2    Gullans, S.R.3
  • 14
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso, O. A., M. Chiariello, J. C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J. S. Gutkind. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81: 1137-1146, 1995.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 15
    • 0027983480 scopus 로고
    • Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: An alternative route to mitogen-induced gene expression
    • de Groot, R. P., L. M. Ballou, and P. Sassone-Corsi. Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression. Cell 79: 81-91, 1994.
    • (1994) Cell , vol.79 , pp. 81-91
    • De Groot, R.P.1    Ballou, L.M.2    Sassone-Corsi, P.3
  • 16
    • 0029155009 scopus 로고
    • Positive regulation of the nuclear activator CREM by the mitogen-induced p70 S6 kinase
    • de Groot, R. P., L. M. Ballou, and P. Sassone-Corsi. Positive regulation of the nuclear activator CREM by the mitogen-induced p70 S6 kinase. Immunobiology 193: 155-160, 1995.
    • (1995) Immunobiology , vol.193 , pp. 155-160
    • De Groot, R.P.1    Ballou, L.M.2    Sassone-Corsi, P.3
  • 17
    • 0028935974 scopus 로고
    • Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard, B., J. Raingeaud, T. Barrett, I.-H. Wu, J. Han, R. J. Ulevitch, and R. J. Davis. Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267: 682-685, 1995.
    • (1995) Science , vol.267 , pp. 682-685
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.-H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 18
    • 0030669546 scopus 로고    scopus 로고
    • Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis
    • Dove, S. K., F. T. Cooke, M. R. Douglas, L. G. Sayers, P. J. Parker, and R. H. Michell. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390: 187-192, 1997.
    • (1997) Nature , vol.390 , pp. 187-192
    • Dove, S.K.1    Cooke, F.T.2    Douglas, M.R.3    Sayers, L.G.4    Parker, P.J.5    Michell, R.H.6
  • 19
    • 15844391440 scopus 로고    scopus 로고
    • Mechanism of action of the immunosuppressant rapamycin
    • Dumont, F. J., and Q. Su. Mechanism of action of the immunosuppressant rapamycin. Life Sci. 58: 373-395, 1996.
    • (1996) Life Sci. , vol.58 , pp. 373-395
    • Dumont, F.J.1    Su, Q.2
  • 20
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enari, M., R. V. Talanian, W. W. Wong, and S. Nagata. Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380: 723-726, 1996.
    • (1996) Nature , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 21
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKT ion blocks apoptosis
    • Franke, T. F., D. R. Kaplan, and L. C. Cantley. PI3K: downstream AKT ion blocks apoptosis. Cell 88: 435-437, 1997.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 22
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T. F., S. I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81: 727-736, 1995.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 23
    • 0025934347 scopus 로고
    • Renal medullary organic osmolytes
    • Garcia-Perez, A., and M. B. Burg. Renal medullary organic osmolytes. Physiol. Rev. 71: 1081-1115, 1991.
    • (1991) Physiol. Rev. , vol.71 , pp. 1081-1115
    • Garcia-Perez, A.1    Burg, M.B.2
  • 24
    • 0026341902 scopus 로고
    • Acute cell volume changes in anisotonic media affect F-actin content of HL-60 cells
    • Corrigenda. Am. J. Physiol. Cell Physiol. 268: March 1995, following table of contents
    • Hallows, K. R., C. H. Packman, and P. A. Knauf. Acute cell volume changes in anisotonic media affect F-actin content of HL-60 cells. Am. J. Physiol. Cell Physiol. 261: C1154-C1161, 1991. [Corrigenda. Am. J. Physiol. Cell Physiol. 268: March 1995, following table of contents]
    • (1991) Am. J. Physiol. Cell Physiol. , vol.261
    • Hallows, K.R.1    Packman, C.H.2    Knauf, P.A.3
  • 25
    • 0028918408 scopus 로고
    • Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase
    • Hu, Q., A. Klippel, A. J. Muslin, W. J. Fantl, and L. T. Williams. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. Science 268: 100-102, 1995.
    • (1995) Science , vol.268 , pp. 100-102
    • Hu, Q.1    Klippel, A.2    Muslin, A.J.3    Fantl, W.J.4    Williams, L.T.5
  • 26
    • 0029790979 scopus 로고    scopus 로고
    • Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
    • Knebel, A., H. J. Rahmsdorf, A. Ullrich, and P. Herrlich. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J. 15: 5314-5325, 1996.
    • (1996) EMBO J. , vol.15 , pp. 5314-5325
    • Knebel, A.1    Rahmsdorf, H.J.2    Ullrich, A.3    Herrlich, P.4
  • 27
    • 17544366309 scopus 로고
    • S6K
    • edited by G. Hardie and S. Hanks. San Diego, CA: Academic
    • Kozma, S. C., and G. Thomas. S6K. In: The Protein Kinase Facts Book, edited by G. Hardie and S. Hanks. San Diego, CA: Academic, 1995, p. 109-111.
    • (1995) The Protein Kinase Facts Book , pp. 109-111
    • Kozma, S.C.1    Thomas, G.2
  • 28
    • 0029938846 scopus 로고    scopus 로고
    • Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes
    • Krause, U., M. H. Rider, and L. Hue. Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes. J. Biol. Chem. 271: 16668-16673, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16668-16673
    • Krause, U.1    Rider, M.H.2    Hue, L.3
  • 29
    • 0024239087 scopus 로고
    • Clinical and biochemical applications of luciferases and luciferins
    • Kricka, L. J. Clinical and biochemical applications of luciferases and luciferins. Anal. Biochem. 175: 14-21, 1988.
    • (1988) Anal. Biochem. , vol.175 , pp. 14-21
    • Kricka, L.J.1
  • 30
    • 0032246299 scopus 로고    scopus 로고
    • Intracellular signaling in response to osmotic stress
    • edited by F. Lang. Basel: Karger
    • Kultz, D., and M. B. Burg. Intracellular signaling in response to osmotic stress. In: Cell Volume Regulation, edited by F. Lang. Basel: Karger, 1998, p. 94-109.
    • (1998) Cell Volume Regulation , pp. 94-109
    • Kultz, D.1    Burg, M.B.2
  • 32
    • 0030771661 scopus 로고    scopus 로고
    • Signaling elements involved in amino acid transport responses to altered muscle cell volume
    • Low, S. Y., M. J. Rennie, and P. M. Taylor. Signaling elements involved in amino acid transport responses to altered muscle cell volume. FASEB J. 11: 1111-1117, 1997.
    • (1997) FASEB J. , vol.11 , pp. 1111-1117
    • Low, S.Y.1    Rennie, M.J.2    Taylor, P.M.3
  • 33
    • 0029028962 scopus 로고
    • Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor
    • Maeda, T., M. Takekawa, and H. Saito. Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor. Science 269: 554-558, 1995.
    • (1995) Science , vol.269 , pp. 554-558
    • Maeda, T.1    Takekawa, M.2    Saito, H.3
  • 34
    • 0028228109 scopus 로고
    • A two-component system that regulates an osmosensing MAP kinase cascade in yeast
    • Maeda, T., S. M. Wurgler-Murphy, and H. Saito. A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369: 242-245, 1994.
    • (1994) Nature , vol.369 , pp. 242-245
    • Maeda, T.1    Wurgler-Murphy, S.M.2    Saito, H.3
  • 35
    • 0029070887 scopus 로고
    • Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
    • Minden, A., A. Lin, F. X. Claret, A. Abo, and M. Karin. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 81: 1147-1157, 1995.
    • (1995) Cell , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.X.3    Abo, A.4    Karin, M.5
  • 37
    • 0024002556 scopus 로고
    • Luciferase reporter gene vectors for analysis of promoters and enhancers
    • Nordeen, S. K. Luciferase reporter gene vectors for analysis of promoters and enhancers. BioTechniques 6: 454-458, 1988.
    • (1988) BioTechniques , vol.6 , pp. 454-458
    • Nordeen, S.K.1
  • 38
    • 0029101360 scopus 로고
    • An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1
    • Olson, M. F., A. Ashworth, and A. Hall. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 269: 1270-1272, 1995.
    • (1995) Science , vol.269 , pp. 1270-1272
    • Olson, M.F.1    Ashworth, A.2    Hall, A.3
  • 39
    • 0029965695 scopus 로고    scopus 로고
    • Integrin-mediated signalling: Regulation by protein tyrosine kinases and small GTP-binding proteins
    • Parsons, J. T. Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins. Current Opin. Cell Biol. 8: 146-152, 1996.
    • (1996) Current Opin. Cell Biol. , vol.8 , pp. 146-152
    • Parsons, J.T.1
  • 40
    • 0029947181 scopus 로고    scopus 로고
    • Requirement for phosphatidylinositol 3′-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin
    • Rankin, S., R. Hooshmand-Rad, L. Claesson-Welsh, and E. Rozengurt. Requirement for phosphatidylinositol 3′-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin. J. Biol. Chem. 271: 7829-7834, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 7829-7834
    • Rankin, S.1    Hooshmand-Rad, R.2    Claesson-Welsh, L.3    Rozengurt, E.4
  • 41
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Rosette, C., and M. Karin. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274: 1194-1197, 1996.
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 42
    • 10544232283 scopus 로고    scopus 로고
    • Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes
    • Sadoshima, J., Z. H. Qiu, J. P. Morgan, and S. Izumo. Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes. EMBO J. 15: 5535-5546, 1996.
    • (1996) EMBO J. , vol.15 , pp. 5535-5546
    • Sadoshima, J.1    Qiu, Z.H.2    Morgan, J.P.3    Izumo, S.4
  • 45
    • 0028242350 scopus 로고
    • Evidence for a functional role of She proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor
    • Sasaoka, T., D. W. Rose, B. H. Jhun, A. R. Saltiel, B. Draznin, and J. M. Olefsky. Evidence for a functional role of She proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J. Biol. Chem. 269: 13689-13694, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13689-13694
    • Sasaoka, T.1    Rose, D.W.2    Jhun, B.H.3    Saltiel, A.R.4    Draznin, B.5    Olefsky, J.M.6
  • 46
    • 0029074997 scopus 로고
    • Activation of extracellular signal-regulated kinases Erk-1 and Erk-2 by cell swelling in H4IIE hepatoma cells
    • Schliess, F., R. Schreiber, and D. Haussinger. Activation of extracellular signal-regulated kinases Erk-1 and Erk-2 by cell swelling in H4IIE hepatoma cells. Biochem. J. 309: 13-17, 1995.
    • (1995) Biochem. J. , vol.309 , pp. 13-17
    • Schliess, F.1    Schreiber, R.2    Haussinger, D.3
  • 47
    • 0029847581 scopus 로고    scopus 로고
    • Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling
    • Schliess, F., R. Sinning, R. Fischer, C. Schmalenbach, and D. Haussinger. Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling. Biochem. J. 320: 167-171, 1996.
    • (1996) Biochem. J. , vol.320 , pp. 167-171
    • Schliess, F.1    Sinning, R.2    Fischer, R.3    Schmalenbach, C.4    Haussinger, D.5
  • 50
    • 0026802515 scopus 로고
    • Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase
    • Soltoff, S. P., S. L. Rabin, L. C. Cantley, and D. R. Kaplan. Nerve growth factor promotes the activation of phosphatidylinositol 3-kinase and its association with the trk tyrosine kinase. J. Biol. Chem. 267: 17472-17477, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 17472-17477
    • Soltoff, S.P.1    Rabin, S.L.2    Cantley, L.C.3    Kaplan, D.R.4
  • 51
    • 0027987790 scopus 로고
    • The tonicity-sensing element that mediates increased transcription of the betaine transporter gene in response to hyperosmotic stress
    • Takenaka, M., A. S. Preston, H. M. Kwon, and J. S. Handler. The tonicity-sensing element that mediates increased transcription of the betaine transporter gene in response to hyperosmotic stress. J. Biol. Chem. 269: 29379-29381, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 29379-29381
    • Takenaka, M.1    Preston, A.S.2    Kwon, H.M.3    Handler, J.S.4
  • 53
    • 0030992837 scopus 로고    scopus 로고
    • Signalling through the lipid products of phosphoinositide-3-OH kinase
    • Toker, A., and L. C. Cantley. Signalling through the lipid products of phosphoinositide-3-OH kinase. Nature 387: 673-676, 1997.
    • (1997) Nature , vol.387 , pp. 673-676
    • Toker, A.1    Cantley, L.C.2
  • 55
    • 0023791129 scopus 로고
    • 5′Flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene
    • Tsai-Morris, C., X. Cao, and V. P. Sukhatme. 5′Flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene. Nucleic Acids Res. 16: 8835-8846, 1988.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 8835-8846
    • Tsai-Morris, C.1    Cao, X.2    Sukhatme, V.P.3
  • 56
    • 0033013888 scopus 로고    scopus 로고
    • Killing of HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein
    • Vocero-Akbani, A. M., N. V. Heyden, N. A. Lissy, L. Ratner, and S. F. Dowdy. Killing of HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein. Nat. Med. 5: 29-33, 1999.
    • (1999) Nat. Med. , vol.5 , pp. 29-33
    • Vocero-Akbani, A.M.1    Heyden, N.V.2    Lissy, N.A.3    Ratner, L.4    Dowdy, S.F.5
  • 57
    • 0028999052 scopus 로고
    • Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation
    • Weng, Q.-P., K. Andrabi, A. Klippel, M. T. Kozlowski, L. T. Williams, and J. Avruch. Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation. Proc. Natl. Acad. Sci. USA 92: 5744-5748, 1995.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5744-5748
    • Weng, Q.-P.1    Andrabi, K.2    Klippel, A.3    Kozlowski, M.T.4    Williams, L.T.5    Avruch, J.6
  • 58
    • 0010403657 scopus 로고    scopus 로고
    • A dominant role of the juxtamembrane region of the TrkA nerve growth factor receptor during neuronal cell differentiation
    • Yoon, S. O., S. P. Soltoff, and M. V. Chao. A dominant role of the juxtamembrane region of the TrkA nerve growth factor receptor during neuronal cell differentiation. J. Biol. Chem. 272: 23231-23238, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23231-23238
    • Yoon, S.O.1    Soltoff, S.P.2    Chao, M.V.3
  • 59
    • 0031659004 scopus 로고    scopus 로고
    • Urea and NaCl differentially regulate focal adhesion kinase (FAK) and PYK2/ RAFTK
    • Zhang, Z., H. Avraham, and D. M. Cohen. Urea and NaCl differentially regulate focal adhesion kinase (FAK) and PYK2/ RAFTK. Am. J. Physiol. Renal Physiol. 275: F447-F451, 1998.
    • (1998) Am. J. Physiol. Renal Physiol. , vol.275
    • Zhang, Z.1    Avraham, H.2    Cohen, D.M.3
  • 60
    • 0030468690 scopus 로고    scopus 로고
    • NaCl but not urea activates p38 and jun kinase in mIMCD3 murine inner medullary cells
    • Zhang, Z., and D. M. Cohen. NaCl but not urea activates p38 and jun kinase in mIMCD3 murine inner medullary cells. Am. J. Physiol. Renal Fluid Electrolyte Physiol. 271: F1234-F1238, 1996.
    • (1996) Am. J. Physiol. Renal Fluid Electrolyte Physiol. , vol.271
    • Zhang, Z.1    Cohen, D.M.2
  • 61
    • 0031755227 scopus 로고    scopus 로고
    • Hypotonicity activates transcription through ERK-dependent and -independent pathways in renal cells
    • Zhang, Z., X. Y. Yang, and D. M. Cohen. Hypotonicity activates transcription through ERK-dependent and -independent pathways in renal cells. Am. J. Physiol. Cell Physiol. 275: C1104-C1112, 1998.
    • (1998) Am. J. Physiol. Cell Physiol. , vol.275
    • Zhang, Z.1    Yang, X.Y.2    Cohen, D.M.3


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